CN105935423A - Zhuang drug for treating dementia - Google Patents

Zhuang drug for treating dementia Download PDF

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Publication number
CN105935423A
CN105935423A CN201610477978.6A CN201610477978A CN105935423A CN 105935423 A CN105935423 A CN 105935423A CN 201610477978 A CN201610477978 A CN 201610477978A CN 105935423 A CN105935423 A CN 105935423A
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CN
China
Prior art keywords
parts
functions
radix
drug
treatment
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Pending
Application number
CN201610477978.6A
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Chinese (zh)
Inventor
陈炜
吴林
胡跃强
蒋凌飞
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Guangxi University of Chinese Medicine
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Guangxi University of Chinese Medicine
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Priority to CN201610477978.6A priority Critical patent/CN105935423A/en
Publication of CN105935423A publication Critical patent/CN105935423A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9062Alpinia, e.g. red ginger or galangal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a Zhuang drug for treating dementia. The Zhuang drug comprises the following raw materials: radix fici simplicissimae, talinum paniculatum, sharpleaf galangal fruit, acorus calamus, blumea balsamifera, cassia twig, and rheum officinale. Radix fici simplicissimae has the functions of invigorating the spleen and stomach, and dredging the fluid passages. Talinum paniculatum has the functions of moistening the lung, stopping coughing, invigorating the spleen, and tonifying deficiency. Sharpleaf galangal fruit has the functions of warming the kidney, arresting polyuria, and securing essence. Acorus calamus has the functions of refreshing and improving the intelligence. Blumea balsamifera can dispel the wind evil and free collaterals and plays as an auxiliary drug. Cassia twig has the functions of warming and freeing channels, reinforcing yang, and removing gas. Rheum officinale can cool the blood and remove toxin and is the main component. The components mentioned above are used together to generate functions of resolving phlegm, eliminating stasis, inducing resuscitation, and freeing the collaterals. The clinic results show that the provided Zhuang drug has the functions of resolving phlegm, eliminating stasis, inducing resuscitation, and freeing the collaterals, is capable of prominently improving the symptoms of dementia, can promote the recovery of normal functions of patients, and has the advantages of definite, rapid, and stable curative effect, and no side or toxic effect.

Description

The strong medicine that treatment is dull-witted
Technical field
The invention belongs to national medicine field, particularly relate to a kind of strong medicine treating dementia.
Background technology
Dementia is a kind of common disease of old people, with hypomnesis, abstract thinking ability decline, Blunting, forget, Learning capacity decline, aphasia, Cognitive deficiency etc. mainly show for Major Clinical.Primary disease is equivalent to the " kind of the traditional Chinese medical science Forget ", also known as " dementia ", alzheimer disease and vascular dementia of belonging to doctor trained in Western medicine etc..Strong doctor thinks within primary disease because main, Due to internal injury caused by excess of seven emotions, prolonged illness is not multiple, and lack of proper care in body deficiency due to old age Deng Zhi tri-road, insufficiency of vital energy and blood, deficiency of kidney-essence, expectorant stasis blocking numbness, gradually Skilful depressed place is made to lose foster, hollow.Its basic pathogenesis is that marrow subtracts brain and disappears, god's machine apraxia, dragon roadlock plug.Its sick position is in skilful depressed place, with miaow In mind, the functional disorder such as miaow alms bowl, miaow waist is closely related.Its Characteristics of Syndromes is with QI and blood, deficiency of kidney-essence for basis, the stasis of blood turbid with expectorant The excess pathogen of blood is mark, the card of clinical common simulataneous insufficiency and excessive.In terms for the treatment of infirmities of age, strong medicine has the treatment of uniqueness always Effect.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of strong medicine treating dementia, and it has reduces phlegm, removing blood stasis, has one's ideas straightened out, logical The merit on dragon road, and curative effect is reliable.
For solving above-mentioned technical problem, the present invention by the following technical solutions: the strong medicine that treatment is dull-witted, including following crude drug Material: Herba Fici Simplicissimae, Radix Talini Paniculati, Fructus Alpiniae Oxyphyllae, Rhizoma Acori Calami, Herba Blumeae Balsamiferae, Ramulus Cinnamomi and Radix Et Rhizoma Rhei.
The dull-witted strong medicine of above-mentioned treatment is made up of the raw medicinal material of following weight portion: Herba Fici Simplicissimae 10~25 parts, Radix Talini Paniculati 30~ 50 parts, Fructus Alpiniae Oxyphyllae 20~40 parts, Rhizoma Acori Calami 20~40 parts, Herba Blumeae Balsamiferae 20~40 parts, Ramulus Cinnamomi 3~9 parts, Radix Et Rhizoma Rhei 3~ 9 parts.
The strong medicine of above-mentioned treatment dementia is made up of the raw medicinal material of following weight portion: Herba Fici Simplicissimae 15 parts, Radix Talini Paniculati 40 parts, Fructus Alpiniae Oxyphyllae 30 parts, Rhizoma Acori Calami 30 parts, Herba Blumeae Balsamiferae 30 parts, Ramulus Cinnamomi 6 parts, Radix Et Rhizoma Rhei 6 parts.
The strong medicine of above-mentioned treatment dementia is decoction.
The strong medicine that above-mentioned treatment is dull-witted, is prepared as follows: after cleaning raw medicinal material the most respectively, adds water logging together Steeping 0.5~1 hour, then intense fire decocts to medicinal liquid and seethes with excitement, then uses slow fire boiling 20~25 minutes instead, is leached by medicine juice, Obtain.
Inventor gives full play to strong medicine advantage, develops the strong medicine that a kind for the treatment of shown unique characteristics is dull-witted, including following raw material Medical material: Herba Fici Simplicissimae, Radix Talini Paniculati, Fructus Alpiniae Oxyphyllae, Rhizoma Acori Calami, Herba Blumeae Balsamiferae, Ramulus Cinnamomi and Radix Et Rhizoma Rhei.Wherein,
Herba Fici Simplicissimae: strong entitled Go ' ujgyazbizdoj, for moraceae plants ficus simplicissima Ficus simplicissima Lour. Root;Property acrid, sweet, warm;Effect: strengthening the spleen and stomach, waterway, stimulating milk secretion;Cure mainly: edema, leucorrhea, puerperal asthenia agalactia.
Radix Talini Paniculati: strong entitled Gosinhdoj, for portulacaceous plant smoke tree orchid Talinum paniculatum (Jacq) Gaertn Root;Property sweet, flat;Effect: nourishing the lung to arrest cough, spleen invigorating qi-restoratives, heat clearing away arresting sweating, adjusting meridian and stopping leukorrhea.Cure mainly: pulmonary tuberculosis, scorching Cough, insufficiency of the spleen overstrain, discharge belly, dizziness, hectic fever, night sweating, hyperhidrosis, menoxenia, leucorrhea is many.
Fructus Alpiniae Oxyphyllae: strong entitled pluck son, for zingiberaceous plant Fructus Alpiniae Oxyphyllae Alpinia oxyphylla Miq, fruit;Property is pungent, Temperature;Effect: spleen antidiarrheal takes the photograph saliva;Warming the kidney reducing urination controlling nocturnal emission with astringent drugs;Cure mainly: vomiting;Have loose bowels;Cold in abdomen educate;The many salivas of mouth;Suffer from a deficiency of the kidney The enuresis;Frequent micturition;Seminal emission;Nebulousurine.
Rhizoma Acori Calami: strong entitled Gosizcanghbuz, for acorus gramineus araceae plant Acorus gramineus Soland.ex Ait. rhizome;Property pungent, temperature;Effect: waking up the patient from unconsciousness by dissipating phlegm, removing dampness to restore normal function of the stomach, refreshment Fructus Alpiniae Oxyphyllae;Cure mainly: damp-phlegm covers key, mind Unclear, humidity hysteresis feeling of fullness, the insufficiency of the spleen belly that discharges, forgetful, traumatic injury, carbuncle, eczema.
Herba Blumeae Balsamiferae: strong entitled Go ' ngaihlaux, for the Herb of feverfew Herba Blumeae Balsamiferae Blumea balsamifera DC.; Property pungent, bitter, temperature, slightly poisonous;Effect: dispelling wind evil, dehumidifying poison, Tong Longlu, repercussive swells, and relieve the pain pain, dissipating blood stasis blood;Main Control: rheumatic ostalgia, puerperal osteodynia, wind syndrome of head pain, traumatic injury, dysmenorrhea, menoxenia, eczema, ulcer of the lower limb.
Ramulus Cinnamomi: for the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl;Property acrid, sweet, warm;Effect: Diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins;Cure mainly: anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, close Joint arthralgia pain, phlegm retention, edema, cardiopalmus, renal mass.
Radix Et Rhizoma Rhei: for polygonum rheum palmatum Rheum palmatum L, Rheum tanguticum Rheum tanguticum Maxim Ex Balf, or the dry root and rhizome of Rheum officinale Rheum officinale Baill.Property bitter, cold.Effect: purge heat Logical intestinal, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation;Curing mainly: excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood is told Nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire;Upper digestive tract Hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.
Fang Xi;Herba Fici Simplicissimae strengthening the spleen and stomach, waterway, Radix Talini Paniculati's nourishing the lung to arrest cough, spleen invigorating qi-restoratives, Fructus Alpiniae Oxyphyllae warming the kidney reducing urination controlling nocturnal emission with astringent drugs Principal agent;Rhizoma Acori Calami waking up the patient from unconsciousness by dissipating phlegm, refreshment Fructus Alpiniae Oxyphyllae adjusts skilful depressed place;Herba Blumeae Balsamiferae: dispelling wind evil, Tong Longlu is side medicine;Ramulus Cinnamomi temperature is led to Passages through which vital energy circulates, supporing yang activating QI;Radix Et Rhizoma Rhei removing pathogenic heat from blood and toxic substance from the body is female medicine, and the main mother of side in full side share, and plays altogether and reduces phlegm, removing blood stasis, has one's ideas straightened out, logical dragon Road.
Clinical practice shows, the present invention treats the strong medical instrument of dementia to be had and reduce phlegm, removing blood stasis, have one's ideas straightened out, and Tong Longlu effect can be substantially Improve dementia symptom, promote the recovery of viability, and determined curative effect, rapidly, stable, have no side effect.
Detailed description of the invention
Embodiment 1
Formula: Herba Fici Simplicissimae 15 grams, Radix Talini Paniculati 30 grams, Fructus Alpiniae Oxyphyllae 20 grams, Rhizoma Acori Calami 20 grams, Herba Blumeae Balsamiferae 20 grams, Ramulus Cinnamomi 3 Gram, Radix Et Rhizoma Rhei 3 grams.
Preparation method: after cleaning raw medicinal material the most respectively, soaks 0.5 hour together, and then intense fire decocts to medicinal liquid boiling, Use slow fire boiling again instead 20 minutes, medicine juice is leached, to obtain final product.
Embodiment 2
Formula: Herba Fici Simplicissimae 15 grams, Radix Talini Paniculati 40 grams, Fructus Alpiniae Oxyphyllae 30 grams, Rhizoma Acori Calami 30 grams, Herba Blumeae Balsamiferae 30 grams, Ramulus Cinnamomi 6 Gram, Radix Et Rhizoma Rhei 6 grams.
Preparation method: after cleaning raw medicinal material the most respectively, soaks 1 hour together, and then intense fire decocts to medicinal liquid boiling, then Use slow fire boiling instead 25 minutes, medicine juice is leached, to obtain final product.
Embodiment 3
Formula: Herba Fici Simplicissimae 25 grams, Radix Talini Paniculati 50 grams, Fructus Alpiniae Oxyphyllae 40 grams, Rhizoma Acori Calami 40 grams, Herba Blumeae Balsamiferae 40 grams, Ramulus Cinnamomi 9 Gram, Radix Et Rhizoma Rhei 9 grams.
Preparation method: after cleaning raw medicinal material the most respectively, soaks 0.75 hour together, and then intense fire decocts to medicinal liquid boiling, Use slow fire boiling again instead 22 minutes, medicine juice is leached, to obtain final product.
The present invention treats the strong medicine administrated method of dementia: the patient being diagnosed as dementia takes above-mentioned decoction, 3 times/1 day, 15 It is 1 course for the treatment of, 3 courses for the treatment of of treatment, drug withdrawal continuously.
Clinical case
Huang, man, 68 years old, suffer from senile dementia February, mainly show as inattentive, hypomnesis, dimly pale tongue, thin fur In vain, deep-thready pulse, it is practiced inattentive improvement after 5 courses for the treatment of of Drug therapy of example 1, memory function takes an evident turn for the better.
Wei, female, 65 years old, suffer from senile dementia 1 year, mainly show as intelligence and decline, hypomnesis, dimly pale tongue, White and thin fur, thready pulse, it is practiced inattentive improvement after 8 courses for the treatment of of Drug therapy of example 2, intelligence and memory function have the biggest Improve.
Chen, female, 70 years old, suffers from senile dementia October, mainly shows as intelligence decline, hypomnesis, hallucination, tongue Matter is dim, white and thin fur, thready and hesitant pulse, and after being practiced 6 courses for the treatment of of Drug therapy of example 3, intelligence and memory function take a favorable turn, Hallucination disappears.

Claims (5)

1. the strong medicine treating dementia, it is characterised in that include following raw medicinal material: Herba Fici Simplicissimae, Radix Talini Paniculati, Fructus Alpiniae Oxyphyllae, Rhizoma Acori Calami, Herba Blumeae Balsamiferae, Ramulus Cinnamomi and Radix Et Rhizoma Rhei.
The strong medicine that treatment the most according to claim 1 is dull-witted, it is characterised in that be made up of the raw medicinal material of following weight portion: Herba Fici Simplicissimae 10~25 parts, Radix Talini Paniculati 30~50 parts, Fructus Alpiniae Oxyphyllae 20~40 parts, Rhizoma Acori Calami 20~40 parts, Ai Na Fragrant 20~40 parts, Ramulus Cinnamomi 3~9 parts, Radix Et Rhizoma Rhei 3~9 parts.
The strong medicine that treatment the most according to claim 2 is dull-witted, it is characterised in that be made up of the raw medicinal material of following weight portion: Herba Fici Simplicissimae 15 parts, Radix Talini Paniculati 40 parts, Fructus Alpiniae Oxyphyllae 30 parts, Rhizoma Acori Calami 30 parts, Herba Blumeae Balsamiferae 30 parts, Ramulus Cinnamomi 6 parts, Radix Et Rhizoma Rhei 6 parts.
The strong medicine that treatment the most according to claim 1 is dull-witted, it is characterised in that for decoction.
The strong medicine that treatment the most according to claim 4 is dull-witted, it is characterised in that be prepared as follows: distinguish by weight After cleaning raw medicinal material, soaking together 0.5~1 hour, then intense fire decocts to medicinal liquid boiling, then uses slow fire instead Decoct 20~25 minutes, medicine juice is leached, to obtain final product.
CN201610477978.6A 2016-06-24 2016-06-24 Zhuang drug for treating dementia Pending CN105935423A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109646573A (en) * 2019-01-23 2019-04-19 广西中医药大学 A kind of enrich blood supports the strong drug composition and preparation method thereof of essence

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CN101637590A (en) * 2009-08-31 2010-02-03 武汉朗琪生物科技有限公司 Traditional Chinese medicine for curing senile dementia
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109646573A (en) * 2019-01-23 2019-04-19 广西中医药大学 A kind of enrich blood supports the strong drug composition and preparation method thereof of essence

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