CN104547190A - Traditional Chinese medicine for treating infantile jaundice - Google Patents

Traditional Chinese medicine for treating infantile jaundice Download PDF

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Publication number
CN104547190A
CN104547190A CN201510025045.9A CN201510025045A CN104547190A CN 104547190 A CN104547190 A CN 104547190A CN 201510025045 A CN201510025045 A CN 201510025045A CN 104547190 A CN104547190 A CN 104547190A
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parts
chinese medicine
cortex
jaundice
traditional chinese
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金思思
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金思思
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree

Abstract

The invention provides a traditional Chinese medicine for treating infantile jaundice. The traditional Chinese medicine is prepared from Tripterygium wilfordii, fructus evodiae, cortex periplocae, magnolia officinalis, semen raphani, tetrapanax papyriferus, melastoma dodecandrum, cortex phellodendri, artichoke, fagopyrum dibotrys, polyporus umbellatus and licorice root. The traditional Chinese medicine can be used for treating infantile jaundice clinically.

Description

A kind of Chinese medicine for the treatment of infantile jaundice
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of infantile jaundice.
Background technology
Infantile jaundice refers to that the abnormal blood mesobilirubin level that causes of bilirubin metabolism raises and occurs the clinical picture of skin, sclera and vigorous film xanthochromia.Jaundice clinically more adopts the comprehensive remedy measures such as the combination of Chinese and Western medicine and phototherapy.Chinese medicine has good effect in the treatment of jaundice, and the Chinese medicine that the present invention prepares to reduce phlegm treatment infantile jaundice with clearing away heat-damp and promoting diuresis, depressed liver-energy dispersing and function of gallbladder promoting, removing toxic substances, achieves good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine to the treatment infantile jaundice of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts Radix Tripterygii Wilfordii, Fructus Evodiae, Cortex Periplocae, Cortex Magnoliae Officinalis, Semen Raphani, Medulla Tetrapanacis, Herba Melastomatis Dodecandri, Cortex Phellodendri, Cynara scolymus L (Cyhara cardunculus.), Rhizoma Fagopyri Dibotryis, Polyporus, Radix Glycyrrhizae is made, according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine of the present invention to be made up of following raw material medicaments: Radix Tripterygii Wilfordii 30-50 part, Fructus Evodiae 20-40 part, Cortex Periplocae 20-40 part, Cortex Magnoliae Officinalis 20-30 part, Semen Raphani 20-30 part, Medulla Tetrapanacis 20-30 part, Herba Melastomatis Dodecandri 20-30 part, Cortex Phellodendri 10-20 part, Cynara scolymus L (Cyhara cardunculus.) 10-20 part, Rhizoma Fagopyri Dibotryis 10-20 part, Polyporus 8-12 part, Radix Glycyrrhizae 8-12 part.
Optimum weight part of raw material of Chinese medicine medicine of the present invention is: Radix Tripterygii Wilfordii 40 parts, Fructus Evodiae 30 parts, Cortex Periplocae 30 parts, Cortex Magnoliae Officinalis 25 parts, Semen Raphani 25 parts, Medulla Tetrapanacis 25 parts, Herba Melastomatis Dodecandri 25 parts, Cortex Phellodendri 15 parts, Cynara scolymus L (Cyhara cardunculus.) 15 parts, Rhizoma Fagopyri Dibotryis 15 parts, Polyporus 10 parts, 10 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Tripterygii Wilfordii: sweet, cold.Return stomach, lung, the heart, wing flesh warp.Cooling blood for hemostasis, clearing away heat and promoting production of body fluid, inducing diuresis for treating stranguria syndrome.Clinical in jaundice, heat in blood is hemorrhage, calentura excessive thirst, gastric heat vomiting, dyspnea and cough due to lung-heat, the puckery pain of dribbling urination, the diseases such as edema.
Fructus Evodiae: bitter, puckery, flat.Return Liver Channel.Astringing to arrest bleeding, regulating menstruation lactogenesis, heat-clearing and toxic substances removing, dampness removing.For spitting of blood, spit blood, discharging fresh blood stool, metrorrhagia, traumatic hemorrhage, newborn woman's agalactia, jaundice, has sore throat, conjunctival congestion and swelling pain, urinary tract infection, and the raw skin ulcer of mouth and nose, carbuncle furuncle and phyma poison waits disease.
Cortex Periplocae: sweet, cold.Return lung, liver, gallbladder meridian.Heat clearing away, dampness removing, laxation, lactogenesis.Clinical in cough due to lung-heat, laryngopharynx swelling and pain, pyretic toxicity dysentery, jaundice due to damp-heat, constipation and anuresis, agalactia, furuncle carbuncle, the diseases such as erysipelas.
Cortex Magnoliae Officinalis: bitter, cold.Return liver, gallbladder, lung meridian.Promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, invigorating blood circulation, it is tired to dispel, expelling phlegm for arresting cough.For jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, carbuncle sore tumefacting virus, venom, cough due to lung-heat etc.
Semen Raphani: bitter, cold.Return stomach, Liver Channel.Expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling.For rheumatic arthralgia, stranguria with turbid discharge, jaundice, rubella convulsion is itched, erysipelas, dental caries, and tooth u such as to swell and ache the disease.
Medulla Tetrapanacis: sweet, light, be slightly cold.Attach to the lung and stomach meridians.Clear wet diuretic, lactogenesis.For the puckery pain of stranguria, dysuria, edema, jaundice, damp-warm diseases, oliguria with reddish urine, puerperal, breast was few, and amenorrhea, is with inferior.
Herba Melastomatis Dodecandri: sweet, puckery, cool.GUIXIN, liver, spleen, lung meridian.Heat-clearing and toxic substances removing, blood circulation promoting and enriching.For high heat, lung abscess, pharyngeal swelling, toothache, dysentery, jaundice, edema, dysmenorrhea, metrorrhagia, leukorrhagia, puerperal abdonimal pain, itch, carbuncle, treats skin ulcer, hemorrhoid, the diseases such as venom.
Cortex Phellodendri: bitter, cold.Return kidney, wing flesh warp.Heat clearing and damp drying, eliminating fire and detoxication.Cure mainly hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever, aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema.
Cynara scolymus L (Cyhara cardunculus.): sweet, flat.Depressed liver-energy dispersing and function of gallbladder promoting, rushes down clearly damp and hot.Clinical in jaundice, two side of body distending pain, the diseases such as damp-heat dysentery.
Rhizoma Fagopyri Dibotryis: sweet, cold, returns liver, stomach warp.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.Skin ulcer, the puckery pain of pyretic stranguria is treated for carbuncle.
Polyporus: sweet, light, flat.Return kidney, wing flesh warp.Promoting diuresis to eliminate damp pathogen.For dysuria, edema, have loose bowels, stranguria with turbid discharge etc.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine.For abundant expectoration cough, pathopyretic ulcer.
Radix Tripterygii Wilfordii cooling blood for hemostasis, inducing diuresis for treating stranguria syndrome in the present invention are monarch drug, and Fructus Evodiae detoxification and promoting urination, Cortex Periplocae clearing away heat-damp and promoting diuresis, Cortex Magnoliae Officinalis promoting the function of the gallbladder to alleviate jaundice are ministerial drug; The wet clearly diuretic of Semen Raphani expelling wind and removing dampness, Medulla Tetrapanacis, Herba Melastomatis Dodecandri heat-clearing and toxic substances removing, promoting blood circulation and hemostasis, Cortex Phellodendri heat clearing and damp drying, Cynara scolymus L (Cyhara cardunculus.) depressed liver-energy dispersing and function of gallbladder promoting, Rhizoma Fagopyri Dibotryis heat-clearing and toxic substances removing, Polyporus promoting diuresis to eliminate damp pathogen, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.The common compatibility of above medicine, plays clearing away heat-damp and promoting diuresis, effect that depressed liver-energy dispersing and function of gallbladder promoting, removing toxic substances are invigorated blood circulation altogether, reaches the object for the treatment of infantile jaundice disease.
Chinese medicine of the present invention is used in 2006 to 2011 the routine patients of clinical observation infantile jaundice disease 200, and clinical report is as follows:
1, physical data
In 200 routine patients, women 102 example, male 98 example, at minimum 4 months of age, maximum 5 years old, the course of disease was many at 2 days to 15 days, 2.6 years old mean age.
2, diagnostic criteria
Appearance yellowing of the skin, yellow distinct, shape is as Pericarpium Citri tangerinae, and agitation is cryed, hesitating to suck, yellowish or reddish urine, constipation, red tongue, yellow and greasy fur and the symptom such as thick.
3, Therapeutic Method
3. 1 prescription: Radix Tripterygii Wilfordii 40g, Fructus Evodiae 30g, Cortex Periplocae 30g, Cortex Magnoliae Officinalis 25g, Semen Raphani 25g, Medulla Tetrapanacis 25g, Herba Melastomatis Dodecandri 25g, Cortex Phellodendri 15g, Cynara scolymus L (Cyhara cardunculus.) 15g, Rhizoma Fagopyri Dibotryis 15g, Polyporus lOg, Radix Glycyrrhizae 10g.
3.2 preparation methoies: said medicine routinely technique makes decoction.
3.3 instructions of taking: each 1 dose, every day 2 times 3 days was 1 course for the treatment of.
4, therapeutic outcome:
4. 1 with reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: binocular and whole skin xanthochromia disappear, and spirit is good, diet recovers normal, and defecation is as usual, and medication checked liver function after 3 months, and every index is normal, follows up a case by regular visits to without recurrence after 1 year;
Effective: binocular and whole skin xanthochromia disappear, spirit, and diet is not good;
Do not heal: binocular and whole skin xanthochromia disappear not obvious, spirit, diet are not good.
4.2 results: in 200 routine patients, cure 150 examples (75%), effective 40 examples (20%), and do not heal 10 examples (5%), and total effective rate is 95%.
5, model case
5. 1 Liu, female, 3 years old, binocular and whole skin jaundice, oliguria yellow skin, as dark brown, was felt sick, vomiting, icteric index 24.Take the Chinese medicine that the present invention treats infantile jaundice to treat, after treating 1 course for the treatment of, this youngster's body temperature is normal, and spirit takes a turn for the better, oneself is logical for stool, and abdominal distention disappears, and diet increases, and binocular and whole skin xanthochromia obviously disappear, urine volume polychrome is yellowish, and tongue fur BOHUANG is slightly greasy, rolling pulse string.Continue to take 1 course for the treatment of, all diseases all disappear, and recovery from illness, follows up a case by regular visits to after 1 year, again do not show effect.Dye, jaundice number is that cellulitis index is normal.
5.2 tall certain, man, 2 years old, skin and binocular xanthochromia, large dry stool, urine was deep yellow, whole skin and sclera severe Huang 22.Take the Chinese medicine that the present invention treats infantile jaundice to treat, after treating 2 courses for the treatment of, all diseases disappear, and it is good to follow up a case by regular visits to development in children after Huang.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine for the treatment of infantile jaundice, it is made up of following raw material medicaments: Radix Tripterygii Wilfordii 30g, Fructus Evodiae 20g, Cortex Periplocae 20g, Cortex Magnoliae Officinalis 20g, Semen Raphani 20g, Medulla Tetrapanacis 20g, Herba Melastomatis Dodecandri 20g, Cortex Phellodendri lOg, Cynara scolymus L (Cyhara cardunculus.) lOg, Rhizoma Fagopyri Dibotryis 10g, Polyporus 8g, Radix Glycyrrhizae 8g.
Embodiment 2, a kind of Chinese medicine for the treatment of infantile jaundice, it is made up of following raw material medicaments: Radix Tripterygii Wilfordii 40g, Fructus Evodiae 30g, Cortex Periplocae 30g, Cortex Magnoliae Officinalis 25g, Semen Raphani 25g, Medulla Tetrapanacis 25g, Herba Melastomatis Dodecandri 25g, Cortex Phellodendri 15g, Cynara scolymus L (Cyhara cardunculus.) 15g, Rhizoma Fagopyri Dibotryis 15g, Polyporus lOg, Radix Glycyrrhizae 10g.
Embodiment 3, a kind of Chinese medicine for the treatment of infantile jaundice, it is made up of following raw material medicaments: Radix Tripterygii Wilfordii 50g, Fructus Evodiae 40g, Cortex Periplocae 40g, Cortex Magnoliae Officinalis 30g, Semen Raphani 30g, Medulla Tetrapanacis 30g, Herba Melastomatis Dodecandri 30g, Cortex Phellodendri 20g, Cynara scolymus L (Cyhara cardunculus.) 20g, Rhizoma Fagopyri Dibotryis 20g, Polyporus 12g, Radix Glycyrrhizae 12g.

Claims (2)

1. treat a Chinese medicine for the yellow cellulitis of children's, it is characterized in that being made up of following crude drug: Radix Tripterygii Wilfordii 30-50 part, Fructus Evodiae 20-40 part, Cortex Periplocae 20-40 part, Cortex Magnoliae Officinalis 20-30 part, Semen Raphani 20-30 part, Medulla Tetrapanacis 20-30 part, Herba Melastomatis Dodecandri 20-30 part, Cortex Phellodendri 10-20 part, Cynara scolymus L (Cyhara cardunculus.) 10-20 part, Rhizoma Fagopyri Dibotryis 10-20 part, Polyporus 8-12 part, Radix Glycyrrhizae 8-12 part.
2. Chinese medicine according to claim 1, is characterized in that being made up of following crude drug: Radix Tripterygii Wilfordii 40 parts, Fructus Evodiae 30 parts, Cortex Periplocae 30 parts, Cortex Magnoliae Officinalis 25 parts, Semen Raphani 25 parts, Medulla Tetrapanacis 25 parts, Herba Melastomatis Dodecandri 25 parts, Cortex Phellodendri 15 parts, Cynara scolymus L (Cyhara cardunculus.) 15 parts, Rhizoma Fagopyri Dibotryis 15 parts, Polyporus 10 parts, 10 parts, Radix Glycyrrhizae.
CN201510025045.9A 2015-01-19 2015-01-19 Traditional Chinese medicine for treating infantile jaundice Pending CN104547190A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924265A (en) * 2017-03-15 2017-07-07 中国科学院昆明植物研究所 Application of the Celastrol in the medicine for preparing treatment cholestatic liver disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
祝东友: "通利法治急重症四则", 《中国中医急症》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924265A (en) * 2017-03-15 2017-07-07 中国科学院昆明植物研究所 Application of the Celastrol in the medicine for preparing treatment cholestatic liver disease
CN106924265B (en) * 2017-03-15 2020-10-27 中国科学院昆明植物研究所 Application of tripterine in preparation of medicine for treating cholestatic liver disease

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Application publication date: 20150429