CN104288426A - Traditional Chinese medicine lotion for treating senile cutaneous pruritus and preparation method thereof - Google Patents
Traditional Chinese medicine lotion for treating senile cutaneous pruritus and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/06—Fungi, e.g. yeasts
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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Abstract
The invention relates to traditional Chinese medicine lotion for treating senile cutaneous pruritus and a preparation method thereof. The traditional Chinese medicine lotion comprises the following traditional Chinese medicine raw materials in parts by weight: 10-20 parts of astragalus, 10-15 parts of angelica, 6-12 parts of radix paeoniae alba, 6-12 parts of radix paeoniae rubra, 6-9 parts of rhizoma chuanxiong, 6-9 parts of safflower, 6-9 parts of radix scrophulariae, 6-9 parts of schizonepeta, 6-9 parts of tribulus terrestris, 10-15 parts of sophora flavescens, 20-30 parts of radix rehmanniae, 9-12 parts of salviae miltiorrhizae, 9-15 parts of cortex dictamni, 9-15 parts of rhizoma alismatis, 10-15 parts of poria cocos, 10-15 parts of common yam rhizome, 10-15 parts of pulp of dogwood fruit, 6-9 parts of frostbitten mulberry leaf, 10-15 parts of fructus kochiae and 6-9 parts of raw licorice; the traditional Chinese medicine raw materials are prepared into lotion, the lotion is used for scrubbing itchy skin parts by using a towel, and the traditional Chinese medicine lotion has the functions of benefiting qi and nourishing blood, nourishing Yin and moistening dryness, cooling blood and calming endogenous wind, and dispelling wind and arresting itching. The traditional Chinese medicine lotion for treating senile cutaneous pruritus and the preparation method thereof provided by the invention are easy to obtain the raw materials, low in cost, convenient to use, exact in curative effect and free of toxic side effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, in particular to a kind of Chinese medicine side of washing can effectively treated because of the relevant senile skin pruritus (as diabetes, hepatopathy, nephropathy etc.) of some disease and the not bright senile skin pruritus of some causes of disease, particularly relate to a kind of Chinese medicine for the treatment of senile skin pruritus and preparation method thereof.
Background technology
Along with socioeconomic develop rapidly, aged tendency of population becomes increasingly conspicuous in China; Due to the change of dietary structure, spectrum of disease is also changing, the sickness rate of diabetes, hepatopathy, nephropathy increases year by year, and the senile skin pruritus sickness rate caused thus is increasing, definite etiology unknown, and western medicine many employings antiallergic, glucocorticoid class medicine, therapeutic effect is general, recurrent exerbation, can not eradicate, and side effect is large etc.Although senile skin pruritus is not anxious, critical illness, Symptoms weight, entire patient's skin pruritus, scratch, notably lie awake all night, and has a strong impact on the quality of life of patient.And the Sui Dynasty of motherland's traditional medicine before more than 1000 years is just on the books, Sui's " General Treatise on the Cause and Symptoms of Diseases " claims " pruritus caused by wind pathogen ", and Chang Yin scratches broken skin skin, and blood stain is innumerable, also known as " itching eruption due to wind-heat in blood ".What have is confined to a place, as places such as scrotum, cysthus, anuses, also known as " cloudy scabies ".Old people's gastrointestinal is weak, and the gastrointestinal side effects such as oral traditional Chinese medicine decoction easily causes nausea, vomit, suffer from abdominal pain, diarrhoea, acupuncture should not operate.For above factor, we select the method for washout, draw recipe in ancient times, proved recipe, in conjunction with modern doctor's experience and modern pharmacological research, then in conjunction with clinical experience, utilize Chinese medicine preparation, regulate whole body QI and blood, reach equilibrium between yin and yang, make its level of getting well, carry out a lot of research and trial, develop the side of washing for the treatment of senile skin pruritus.
Summary of the invention
The object of the invention is to overcome that above-mentioned deficiency of the prior art provides that a kind of raw material is easy to get, inexpensive, easy to use, determined curative effect, the Chinese medicine side of washing for the treatment of senile skin pruritus that has no side effect and preparation method thereof.
Technical scheme of the present invention is achieved in that a kind of Chinese medicine side of washing for the treatment of senile skin pruritus, it is characterized in that: the described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 15 parts, the Radix Paeoniae Alba 6 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Rhizoma Chuanxiong 6 ~ 9 parts, 6 ~ 9 parts, Flos Carthami, Radix Scrophulariae 6 ~ 9 parts, Herba Schizonepetae 6 ~ 9 parts, Fructus Tribuli 6 ~ 9 parts, Radix Sophorae Flavescentis 10 ~ 15 parts, 20 ~ 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 ~ 12 parts, Cortex Dictamni 9 ~ 15 parts, Rhizoma Alismatis 9 ~ 15 parts, 10 ~ 15 parts, Poria, Rhizoma dioscoreae 10 ~ 15 parts, Fructus Corni 10 ~ 15 parts, Folium Mori 6 ~ 9 parts, the Fructus Kochiae 10 ~ 15 parts, Radix Glycyrrhizae 6 ~ 9 parts.
The described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 10 parts, Radix Angelicae Sinensis 10 parts, the Radix Paeoniae Alba 6 parts, Radix Paeoniae Rubra 6 parts, Rhizoma Chuanxiong 6 parts, 6 parts, Flos Carthami, Radix Scrophulariae 6 parts, Herba Schizonepetae 6 parts, Fructus Tribuli 6 parts, Radix Sophorae Flavescentis 10 parts, 20 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 parts, Cortex Dictamni 9 parts, Rhizoma Alismatis 9 parts, 10 parts, Poria, Rhizoma dioscoreae 10 parts, Fructus Corni 10 parts, Folium Mori 6 parts, the Fructus Kochiae 10 parts, Radix Glycyrrhizae 6 parts.
The described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 15 parts, Radix Angelicae Sinensis 13 parts, the Radix Paeoniae Alba 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Chuanxiong 7.5 parts, 7.5 parts, Flos Carthami, Radix Scrophulariae 7.5 parts, Herba Schizonepetae 7.5 parts, Fructus Tribuli 7.5 parts, Radix Sophorae Flavescentis 13 parts, 25 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 10.5 parts, Cortex Dictamni 12 parts, Rhizoma Alismatis 12 parts, 13 parts, Poria, Rhizoma dioscoreae 13 parts, Fructus Corni 13 parts, Folium Mori 7.5 parts, the Fructus Kochiae 13 parts, Radix Glycyrrhizae 7.5 parts.
The described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 20 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 12 parts, Radix Paeoniae Rubra 12 parts, Rhizoma Chuanxiong 9 parts, 9 parts, Flos Carthami, Radix Scrophulariae 9 parts, Herba Schizonepetae 9 parts, Fructus Tribuli 9 parts, Radix Sophorae Flavescentis 15 parts, 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 12 parts, Cortex Dictamni 15 parts, Rhizoma Alismatis 15 parts, 15 parts, Poria, Rhizoma dioscoreae 15 parts, Fructus Corni 15 parts, Folium Mori 9 parts, the Fructus Kochiae 15 parts, Radix Glycyrrhizae 9 parts.
The described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 15 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Chuanxiong 6 parts, 9 parts, Flos Carthami, Radix Scrophulariae 9 parts, Herba Schizonepetae 9 parts, Fructus Tribuli 9 parts, Radix Sophorae Flavescentis 12 parts, 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 parts, Cortex Dictamni 12 parts, Rhizoma Alismatis 12 parts, 12 parts, Poria, Rhizoma dioscoreae 13 parts, Fructus Corni 13 parts, Folium Mori 6 parts, the Fructus Kochiae 12 parts, Radix Glycyrrhizae 9 parts.
A kind of Chinese medicine side of washing preparation method for the treatment of senile skin pruritus, the method comprises: the raw material of Chinese medicine following parts by weight: the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 15 parts, the Radix Paeoniae Alba 6 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Rhizoma Chuanxiong 6 ~ 9 parts, 6 ~ 9 parts, Flos Carthami, Radix Scrophulariae 6 ~ 9 parts, Herba Schizonepetae 6 ~ 9 parts, Fructus Tribuli 6 ~ 9 parts, Radix Sophorae Flavescentis 10 ~ 15 parts, 20 ~ 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 ~ 12 parts, Cortex Dictamni 9 ~ 15 parts, Rhizoma Alismatis 9 ~ 15 parts, 10 ~ 15 parts, Poria, Rhizoma dioscoreae 10 ~ 15 parts, Fructus Corni 10 ~ 15 parts, Folium Mori 6 ~ 9 parts, the Fructus Kochiae 10 ~ 15 parts and Radix Glycyrrhizae 6 ~ 9 parts put into decocting medicine pot, add the water of 800 parts by weight, after first soaking half an hour, intense fire decocts 30 minutes, 10 minutes at a simmer afterwards, medicinal liquid is poured in bathtub and cool to 40 ~ 50 DEG C.
The pharmacological property of various raw material of Chinese medicine is as follows:
The side of washing of this patent is made up of Radix Paeoniae Rubra, the Radix Paeoniae Alba the recipe such as Radix Angelicae Sinensis decoction for tonifying blood, SIWU TANG, LIUWEI DIHUANG WAN, kuh-seng soup, chaste tree be anti-scattered and medicine.
The Radix Astragali, Radix Angelicae Sinensis in the side of washing, composition Radix Angelicae Sinensis decoction for tonifying blood, the sweet temperature of the Radix Astragali, the gas strengthened the spleen and stomach, qi promoting blood production, because tangible blood can not be spontaneous, is born in invisible gas.Radix Angelicae Sinensis Xin Ganwen, replenishing blood and nourishing liver, two medicine compatibilities, benefiting qi and nourishing blood.
Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, the Radix Rehmanniae in the side of washing, composition SIWU TANG.SIWU TANG is the basic prescription of enriching blood, and is also the main formula of enriching blood.The Radix Rehmanniae in the side of washing, sweet in the mouth cold in nature and succulence, join the army, blood system, has the feature of " cold and do not coagulate, profit and oiliness ", the special clearing away heat and cooling blood of merit, YIN nourishing and the production of body fluid promoting.Zhang Jiegu cloud: " Radix Rehmanniae raw then Great Cold and removing heat from blood, heat in blood person must use it." " pearl sac " cloud Radix Rehmanniae: " the kidney invigorating water is Kidney-Yin for removing heat from blood, hemopoietic." Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver and battalion, Rhizoma Chuanxiong blood-activating and qi-promoting, harmonizing the functional activities of vital QI, wherein the Radix Rehmanniae, the Radix Paeoniae Alba are cloudy soft product, compatible with pungent using warming therapy Radix Angelicae Sinensis, Rhizoma Chuanxiong, then enrich blood and not stagnant blood, and blood and non-blood trouble.Four things match, and function nourishes blood and blood, and nutrient blood can be made to be in harmonious proportion.
The Radix Rehmanniae, Rhizoma Dioscoreae, Fructus Corni, Poria, Rhizoma Alismatis in the side of washing, namely LIUWEI DIHUANG WAN removes Cortex Moutan, Radix Rehmanniae changes the Radix Rehmanniae into.LIUWEI DIHUANG WAN system Song Qian Yicong " Medical Treasures of the Golden Chamber " shenqi pill deducts Cortex Cinnamomi, Radix Aconiti Lateralis Preparata forms, with controlling the timid all cards of kidney.Radix Rehmanniae changes the Radix Rehmanniae into, and theoretical according to " yi and Kui are derived from the same origin ", The liver and the kidney have a common source, and the kidney invigorating and tonifying liver, stress enriching yin and nourishing kidney; Fructus Corni takes a tonic or nourishing food to build up one's health Liver and kidney, and energy arresting seminal emission; Rhizoma Dioscoreae takes a tonic or nourishing food to build up one's health spleen the moon, also can controlling nocturnal emission with astringent drugs, and three medicines match, and nourishes liver spleen kidney.Compatibility Rhizoma Alismatis dampness removing is let out turbid, and the taste of the anti-sweet cool Radix Rehmanniae is greasy; The light spleen that oozes of Poria wets, and helps the strong fortune of Rhizoma Dioscoreae, and five medicines share, reinforcing and reducing concurrently.
Radix Sophorae Flavescentis in the side of washing, i.e. kuh-seng soup, this side is derived from Chinese Zhang Zhongjing " Medical Treasures of the Golden Chamber Bulbus Lilii oral-anal-genital ulcer syndrome YIN YANG toxin syndrome abnormal pulse card controls the 3rd ", recording: " ulceration at external genitals is dry pharynx then, and kuh-seng soup washes it ", is treatment hu huo syndrome, Symptoms is: the front erosion of the vulva is rotten, dry laryngopharynx, pruritus vulvae.Affected part, kuh-seng soup fumigation and wash method external genitalia, parasite killing removing toxic substances removing dampness is antipruritic.And its Symptoms is similar to senile skin pruritus, therefore, coordinate all medicine washouts, there is effect that removing toxic substances removing dampness is antipruritic.
Herba Schizonepetae, Radix Saposhnikoviae in the side of washing, composition chaste tree is anti-scattered, essentials of Matea Medica cloud: " Herba Schizonepetae, merit originally controls blood, and the double person that controls blood, enters viscus attriguted to wind and wood with it again, be namely the ground of store blood also.Radix Saposhnikoviae abnormal smells from the patient all rises, warm in nature and moisten, and is apt to away the part of the body cavity above the diaphragm housing the heart and lungs, and walks Yu Shangxuan and reach relieving the exterior syndrome, and the power of expelling wind and dampness increases." two medicine compatibility dispelling wind for relieving itching.
Radix Paeoniae Rubra, the Radix Paeoniae Alba in the side of washing, namely famous for medicine, Radix Paeoniae Rubra is bitter and be slightly cold, and property is fallen apart, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, pain relieving, with rush down for.Shennong's Herbal speech Radix Paeoniae Rubra " main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, cold and heat hernia abdominal mass, pain relieving, diuresis ", Radix Paeoniae Alba picric acid is sweet cold, and property is fallen apart, and nourishes blood, easing the affected liver to relieve pain, yin fluid astringing, with mend for." book on Chinese herbal medicine is looked for the truth " cloud: " Radix Paeoniae Rubra and Radix Paeoniae Alba cure mainly slightly same, but then have the power of yin fluid astringing benefit battalion in vain, red, only have the meaning of loose strange blood; Bai Zeneng rushes down wood in soil, red then can live in blood stagnant." two medicines share, one loose one holds back, and one mends one rushes down, and plays clearing away heat and cooling blood altogether, blood circulation promoting and blood stasis dispelling, the merit nourishing blood and seek.
The Fructus Kochiae in the side of washing, arduous gas is trembled with fear, and walks off-balancesheet and to fall apart the wind of skin and antipruritic, enters inner interior clearing away damp-heat and diuresis.
The pungent loose hardship of Fructus Tribuli is let out, and Chhnang is evacuated, and can declare loose exterior multiplication wind heat, dispelling wind for relieving itching, again can be soothing the liver; Cortex Dictamni, bitter salty-cold, heat clearing and damp drying, dispelling wind for relieving itching, removing toxic substances.
Flos Carthami, acrid in the mouth, warm in nature, pungent loose temperature is led to, and has promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.The many stasis of bloods of prolonged illness, the easy stasis of blood of QI and blood is stagnant, and therefore, Flos Carthami and Rhizoma Chuanxiong, Radix Paeoniae Rubra are compatible, promoting blood circulation to restore menstrual flow, QI and blood regulating.
Folium Mori: Folium Mori are the leaf of moraceae plants Mulberry, the leaf beaten through frost of gathering after gathering 10-11 Frost's Descent in month, removing withe and impurity, dry and be Folium Mori, have dispelling wind liver heat removing, the effect that removing heat from blood is moisturized.Modern pharmacological research shows, fresh mulberry leaf water decoction experiment in vitro, all has stronger antibacterial action to staphylococcus aureus, beta hemolytic streptococcus, diphtheria corynebacterium and anthrax bacillus; Folium Mori water decoction high concentration has anti-leptospira effect in vitro, therefore, decocts soup washout, has the effect of sterilization antiinflammatory.
Radix Glycyrrhizae, sweet in the mouth is put down, and decocts soup washout and has eliminating fire and detoxication, the effect of removing heat from blood skin moistening.Tool modern pharmacological research, Radix Glycyrrhizae has nonspecific immunostimulant and the effect of similar mineralocorticoid desoxycortone.Therefore, decoct soup washout, there is antiinflammatory, reduce and ooze out, the effects such as antiallergic.
In a word, Chinese medicine, all medicine compatibilities, decoct soup washout, reach benefiting qi and nourishing blood, and nourshing Yin and drynsessmoistening prescription, removing heat from blood relieves dizziness, high fever, infantile convulsions, epilepsy, etc., effect of dispelling wind for relieving itching.
The good effect that technical scheme of the present invention produces is as follows: prescription of the present invention is rigorous, and preparation technology is simple, easily grasps, easy to operate, washout has no side effect, economical and practical, is suitable for the patient of most of old people's skin pruritus, skin pruritus for the old people that there is following symptom has obvious curative effects: xerosis cutis, pruritus, blood stain spreads all over, lusterless complexion or see dizziness, nervous, insomnia, stringy and thready pulse, light red tongue, uncoated tongue surface like a mirror etc.; This Chinese medicine side of washing has benefiting qi and nourishing blood, and nourshing Yin and drynsessmoistening prescription, removing heat from blood relieves dizziness, high fever, infantile convulsions, epilepsy, etc., effect of dispelling wind for relieving itching.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is further elaborated.
Embodiment one
A kind of Chinese medicine side of washing for the treatment of senile skin pruritus, comprising: Radix Astragali 10g, Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 6g, Radix Paeoniae Rubra 6g, Rhizoma Chuanxiong 6g, Flos Carthami 6g, Radix Scrophulariae 6g, Herba Schizonepetae 6g, Fructus Tribuli 6g, Radix Sophorae Flavescentis 10g, Radix Rehmanniae 20g, Radix Salviae Miltiorrhizae 9g, Cortex Dictamni 9g, Rhizoma Alismatis 9g, Poria 10g, Rhizoma dioscoreae 10g, Fructus Corni 10g, Folium Mori 6g, Fructus Kochiae 10g, Radix Glycyrrhizae 6g.
The preparation method of this Chinese medicine side of washing is as follows: added by the raw material of Chinese medicine of above-mentioned weight in decocting medicine pot (marmite is optimum), add 800ml water, after first soaking half an hour, intense fire decocts 30 minutes, 10 minutes at a simmer afterwards, take medicinal liquid and be about 500ml, pour in bathtub, wait for that fluid temperature is down to 50 DEG C and (or is soundd out with hands, conscious non-scald on hand, actual temp instrument individual tolerate and determine), in order to avoid skin ambustion, especially the old man of the diseases such as diabetes is suffered from, to the paraesthesia of temperature, washout should be assisted by household, towel off and wash skin pruritus position, remaining medicinal residues can be reused, save medical material.
Embodiment two
A kind of Chinese medicine side of washing for the treatment of senile skin pruritus, comprising: Radix Astragali 15g, Radix Angelicae Sinensis 13g, Radix Paeoniae Alba 9g, Radix Paeoniae Rubra 9g, Rhizoma Chuanxiong 7.5g, Flos Carthami 7.5g, Radix Scrophulariae 7.5g, Herba Schizonepetae 7.5g, Fructus Tribuli 7.5g, Radix Sophorae Flavescentis 13g, Radix Rehmanniae 25g, Radix Salviae Miltiorrhizae 10.5g, Cortex Dictamni 12g, Rhizoma Alismatis 12g, Poria 13g, Rhizoma dioscoreae 13g, Fructus Corni 13g, Folium Mori 7.5g, Fructus Kochiae 13g, Radix Glycyrrhizae 7.5g.
The preparation method of this Chinese medicine side of washing is as follows: added by the raw material of Chinese medicine of above-mentioned weight in decocting medicine pot (marmite is optimum), add 800ml water, after first soaking half an hour, intense fire decocts 30 minutes, 10 minutes at a simmer afterwards, take medicinal liquid and be about 500ml, pour in bathtub, wait for that fluid temperature is down to 50 DEG C and (or is soundd out with hands, conscious non-scald on hand, actual temp instrument individual tolerate and determine), in order to avoid skin ambustion, especially the old man of the diseases such as diabetes is suffered from, to the paraesthesia of temperature, washout should be assisted by household, towel off and wash skin pruritus position, remaining medicinal residues can be reused, save medical material.
Embodiment three
A kind of Chinese medicine side of washing for the treatment of senile skin pruritus, comprising: Radix Astragali 20g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 12g, Radix Paeoniae Rubra 12g, Rhizoma Chuanxiong 9g, Flos Carthami 9g, Radix Scrophulariae 9g, Herba Schizonepetae 9g, Fructus Tribuli 9g, Radix Sophorae Flavescentis 15g, Radix Rehmanniae 30g, Radix Salviae Miltiorrhizae 12g, Cortex Dictamni 15g, Rhizoma Alismatis 15g, Poria 15g, Rhizoma dioscoreae 15g, Fructus Corni 15g, Folium Mori 9g, Fructus Kochiae 15g, Radix Glycyrrhizae 9g.
The preparation method of this Chinese medicine side of washing is as follows: added by the raw material of Chinese medicine of above-mentioned weight in decocting medicine pot (marmite is optimum), add 800ml water, after first soaking half an hour, intense fire decocts 30 minutes, 10 minutes at a simmer afterwards, take medicinal liquid and be about 500ml, pour in bathtub, wait for that fluid temperature is down to 50 DEG C and (or is soundd out with hands, conscious non-scald on hand, actual temp instrument individual tolerate and determine), in order to avoid skin ambustion, especially the old man of the diseases such as diabetes is suffered from, to the paraesthesia of temperature, washout should be assisted by household, towel off and wash skin pruritus position, remaining medicinal residues can be reused, save medical material.
Embodiment four
A kind of Chinese medicine side of washing for the treatment of senile skin pruritus, comprising: Radix Astragali 15g, Radix Angelicae Sinensis 12g, Radix Paeoniae Alba 9g, Radix Paeoniae Rubra 9g, Rhizoma Chuanxiong 6g, Flos Carthami 9g, Radix Scrophulariae 9g, Herba Schizonepetae 9g, Fructus Tribuli 9g, Radix Sophorae Flavescentis 12g, Radix Rehmanniae 30g, Radix Salviae Miltiorrhizae 9g, Cortex Dictamni 12g, Rhizoma Alismatis 12g, Poria 12g, Rhizoma dioscoreae 13g, Fructus Corni 13g, Folium Mori 6g, Fructus Kochiae 12g, Radix Glycyrrhizae 9g.
The preparation method of this Chinese medicine side of washing is as follows: added by the raw material of Chinese medicine of above-mentioned weight in decocting medicine pot (marmite is optimum), add 800ml water, after first soaking half an hour, intense fire decocts 30 minutes, 10 minutes at a simmer afterwards, take medicinal liquid and be about 500ml, pour in bathtub, wait for that fluid temperature is down to 50 DEG C and (or is soundd out with hands, conscious non-scald on hand, actual temp instrument individual tolerate and determine), in order to avoid skin ambustion, especially the old man of the diseases such as diabetes is suffered from, to the paraesthesia of temperature, washout should be assisted by household, towel off and wash skin pruritus position, remaining medicinal residues can be reused, save medical material.
Therapeutic effect is analyzed:
One, physical data and method
1, physical data
The senile skin pruritus patient agreeing to participate in this research is chosen the senile pruritus patient gone to a doctor at my Out-patient Department from April, 2012 ~ 2014 year February.Inclusion criteria: allly meet senile skin pruritus diagnostic criteria; Age was at >=60 years old; Onset or recurrence, with the passing of time the course of disease delays, recurrent exerbation; Can be followed the doctor's advice medication and periodic treatments person.And exclusion standard: be associated with the serious primary disease person such as Cardial or cerebral vascular diseases, liver, kidney and hemopoietic system, psychotic, the medicine of 2 weeks these medicines of interior application treatment and glucocorticoid treatment person.Those selected is totally 110 examples, male 82 example (74.5%); Women 28 example (25.5%), 60 ~ 85 years old age, 71.2 ± 5.3 years old mean age.
2, method
Two groups are divided at random, treatment group 56 example, matched group 54 example, the aspect comparing difference not statistically significants (p > 0.05) such as two groups of Genders, age, courses of disease by medical order.
2.1, treatment group
The patient for the treatment of group uses the Chinese medicine side of washing that in above-described embodiment one to four, any one embodiment is obtained, and towel off for twice on the one and wash skin pruritus position, remaining medicinal residues can be reused, and saves medical material.
2.2, matched group
Matched group patient oral hydrochloride cetirizine dispersible tablet (kind peaceful) the accurate word H20040308 of traditional Chinese medicines (Yichang Changjiang Pharmaceutical Co., Ltd.'s production) 10mg/ sheet, sleeps first 1 at every turn.
3, points for attention
Two groups of patients note keeping skin clean at treatments period; Avoid the soap contacting highly basic; Underwear is advisable with the cotton goods of softness; Avoid pungent food, the smell of urine send out food; Do not drink; Keep sufficient sleep.
Two, clinical observation
Two groups was all a course for the treatment of with one month, and the changes such as continuous use observed skin area after 7 days, pruritus degree, carry out efficacy evaluation.Relapse rate is observed after 2 courses for the treatment of.
1, observation index and standards of grading
1.1, subjective symptoms: (pruritus degree) 0 is divided into without pruritus; 1 is divided into slight pruritus, can control not grab; 2 are divided into moderate pruritus, on daily life without impact; 3 are divided into obvious pruritus, but still can stand; 4 are divided into severe pruritus, are impatient at, and impact sleep.
1.2, skin lesion area: it is 4 points that erythra area accounts for body surface area > 75%, 51% ~ 75% is 3 points, and 26% ~ 50% is 2 points, < 25% point 1 point.
1.3, change of skin: 0 point: skin is moist, without squama, without scratch and blood crusts, without erythra; 1 point: slightly dry, without uncomfortable, see white bran shape fines after grabbing, scratch, blood crusts < body surface area 1/3, be dispersed in syringe needle to the large Semen Phaseoli rash of Semen phaseoli radiati, account for 1/3 of body surface area; 3 points: obviously dry, obvious tight sense, and see that skin has trickle slight crack, little shape sheet squama, scratch, blood crusts accounts for 1/3 ~ 2/3 of body surface area, and pimple accounts for 1/3 ~ 2/3 of body surface area, and partial fusion is in blocks; 4 points: extremely dry, have the trace that obviously breaks, companion's mild pain, 2/3 of obvious desquamation, scratch, blood crusts > body surface area, erythra exceedes 2/3 of body surface area, most fusion, lichenization.
Total mark=subjective symptoms integration+skin lesion area integral+skin lesion integration.
3, assessment method
3.1, skin lesion is disappeared=front total mark of (treatment before total mark-treatment after total mark) × 100%/treatment
3.2, Outcome measure: point recovery from illness, effective, effective, invalid level Four, disappears by skin lesion and judges.Recovery from illness: skin lesion disappears more than 95%; Effective: skin lesion disappears 70% ~ 95%; Effective: skin lesion disappears 50 ~ 70%; Invalid: skin lesion is disappeared < 50%.
4, statistical procedures
Data acquisition SPSS18.0 software carries out statistical analysis, thus measurement data data with mean+standard deviation (
) represent, measurement data t checks, enumeration data x
2inspection.
5, result
Matched group total effective rate 72.2%, treatment group total effective rate 89.3%, 2 groups of comparing differences have statistical significance (p < 0.05), and treatment group clinical efficacy is better than matched group (see table 1).Two groups of relapse rate treatment groups are 8.9%, and matched group is that 22.2%, 2 groups of comparing differences have statistical significance (p < 0.05), and treatment group clinical efficacy is better than matched group (see table 2).
Table 1 liang group Clinical efficacy comparison table [example (%)]
Can learn from table 1, treatment group total effective rate is obviously better than matched group (p < 0.05).
Table 2 liang group Clinical efficacy comparison table [example (%)]
Can learn from table 2, treatment group relapse rate is starkly lower than matched group (p < 0.05).
Claims (6)
1. treat the Chinese medicine side of washing of senile skin pruritus for one kind, it is characterized in that: the described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 15 parts, the Radix Paeoniae Alba 6 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Rhizoma Chuanxiong 6 ~ 9 parts, 6 ~ 9 parts, Flos Carthami, Radix Scrophulariae 6 ~ 9 parts, Herba Schizonepetae 6 ~ 9 parts, Fructus Tribuli 6 ~ 9 parts, Radix Sophorae Flavescentis 10 ~ 15 parts, 20 ~ 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 ~ 12 parts, Cortex Dictamni 9 ~ 15 parts, Rhizoma Alismatis 9 ~ 15 parts, 10 ~ 15 parts, Poria, Rhizoma dioscoreae 10 ~ 15 parts, Fructus Corni 10 ~ 15 parts, Folium Mori 6 ~ 9 parts, the Fructus Kochiae 10 ~ 15 parts, Radix Glycyrrhizae 6 ~ 9 parts.
2. a kind of Chinese medicine side of washing for the treatment of senile skin pruritus as claimed in claim 1, is characterized in that: the described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 10 parts, Radix Angelicae Sinensis 10 parts, the Radix Paeoniae Alba 6 parts, Radix Paeoniae Rubra 6 parts, Rhizoma Chuanxiong 6 parts, 6 parts, Flos Carthami, Radix Scrophulariae 6 parts, Herba Schizonepetae 6 parts, Fructus Tribuli 6 parts, Radix Sophorae Flavescentis 10 parts, 20 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 parts, Cortex Dictamni 9 parts, Rhizoma Alismatis 9 parts, 10 parts, Poria, Rhizoma dioscoreae 10 parts, Fructus Corni 10 parts, Folium Mori 6 parts, the Fructus Kochiae 10 parts, Radix Glycyrrhizae 6 parts.
3. a kind of Chinese medicine side of washing for the treatment of senile skin pruritus as claimed in claim 1, is characterized in that: the described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 15 parts, Radix Angelicae Sinensis 13 parts, the Radix Paeoniae Alba 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Chuanxiong 7.5 parts, 7.5 parts, Flos Carthami, Radix Scrophulariae 7.5 parts, Herba Schizonepetae 7.5 parts, Fructus Tribuli 7.5 parts, Radix Sophorae Flavescentis 13 parts, 25 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 10.5 parts, Cortex Dictamni 12 parts, Rhizoma Alismatis 12 parts, 13 parts, Poria, Rhizoma dioscoreae 13 parts, Fructus Corni 13 parts, Folium Mori 7.5 parts, the Fructus Kochiae 13 parts, Radix Glycyrrhizae 7.5 parts.
4. a kind of Chinese medicine side of washing for the treatment of senile skin pruritus as claimed in claim 1, is characterized in that: the described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 20 parts, Radix Angelicae Sinensis 15 parts, the Radix Paeoniae Alba 12 parts, Radix Paeoniae Rubra 12 parts, Rhizoma Chuanxiong 9 parts, 9 parts, Flos Carthami, Radix Scrophulariae 9 parts, Herba Schizonepetae 9 parts, Fructus Tribuli 9 parts, Radix Sophorae Flavescentis 15 parts, 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 12 parts, Cortex Dictamni 15 parts, Rhizoma Alismatis 15 parts, 15 parts, Poria, Rhizoma dioscoreae 15 parts, Fructus Corni 15 parts, Folium Mori 9 parts, the Fructus Kochiae 15 parts, Radix Glycyrrhizae 9 parts.
5. a kind of Chinese medicine side of washing for the treatment of senile skin pruritus as claimed in claim 1, is characterized in that: the described Chinese medicine side of washing comprises the raw material of Chinese medicine of following parts by weight: the Radix Astragali 15 parts, Radix Angelicae Sinensis 12 parts, the Radix Paeoniae Alba 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Chuanxiong 6 parts, 9 parts, Flos Carthami, Radix Scrophulariae 9 parts, Herba Schizonepetae 9 parts, Fructus Tribuli 9 parts, Radix Sophorae Flavescentis 12 parts, 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 parts, Cortex Dictamni 12 parts, Rhizoma Alismatis 12 parts, 12 parts, Poria, Rhizoma dioscoreae 13 parts, Fructus Corni 13 parts, Folium Mori 6 parts, the Fructus Kochiae 12 parts, Radix Glycyrrhizae 9 parts.
6. treat the Chinese medicine side of the washing preparation method of senile skin pruritus for one kind, it is characterized in that: the method comprises: the raw material of Chinese medicine following parts by weight: the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 15 parts, the Radix Paeoniae Alba 6 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Rhizoma Chuanxiong 6 ~ 9 parts, 6 ~ 9 parts, Flos Carthami, Radix Scrophulariae 6 ~ 9 parts, Herba Schizonepetae 6 ~ 9 parts, Fructus Tribuli 6 ~ 9 parts, Radix Sophorae Flavescentis 10 ~ 15 parts, 20 ~ 30 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 9 ~ 12 parts, Cortex Dictamni 9 ~ 15 parts, Rhizoma Alismatis 9 ~ 15 parts, 10 ~ 15 parts, Poria, Rhizoma dioscoreae 10 ~ 15 parts, Fructus Corni 10 ~ 15 parts, Folium Mori 6 ~ 9 parts, the Fructus Kochiae 10 ~ 15 parts and Radix Glycyrrhizae 6 ~ 9 parts put into decocting medicine pot, add the water of 800 parts by weight, after first soaking half an hour, intense fire decocts 30 minutes, 10 minutes at a simmer afterwards, medicinal liquid is poured in bathtub and cool to 40 ~ 50 DEG C.
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CN104771675A (en) * | 2015-04-25 | 2015-07-15 | 奉化科创科技服务有限公司 | Medicine for treating skin itch |
CN104784346A (en) * | 2015-03-03 | 2015-07-22 | 纪书蒙 | Pruritus treating traditional Chinese medicine lotion preparation method |
CN105395447A (en) * | 2015-11-30 | 2016-03-16 | 黄春美 | Liquid shampoo with anti-dandruff function |
CN105902655A (en) * | 2016-06-28 | 2016-08-31 | 孙明香 | Traditional Chinese medicine fuming-washing liquid for treating scalp itch and preparation method of traditional Chinese medicine fuming-washing liquid |
CN106798807A (en) * | 2017-02-16 | 2017-06-06 | 成都富豪斯生物科技有限公司 | A kind of Wash-out medicine and preparation method for treating senile skin pruritus |
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CN104771675A (en) * | 2015-04-25 | 2015-07-15 | 奉化科创科技服务有限公司 | Medicine for treating skin itch |
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