CN106309596A - Compound pure natural granule for treating cold and preparation method thereof - Google Patents
Compound pure natural granule for treating cold and preparation method thereof Download PDFInfo
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- CN106309596A CN106309596A CN201610860909.3A CN201610860909A CN106309596A CN 106309596 A CN106309596 A CN 106309596A CN 201610860909 A CN201610860909 A CN 201610860909A CN 106309596 A CN106309596 A CN 106309596A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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Abstract
The invention discloses a compound pure natural granule for treating cold and a preparation method thereof. The compound pure natural granule is prepared from the following major ingredients in parts by weight: 20 to 25 parts of goldenseal extracts, 8 to 10 parts of echinacea extracts, 15 to 20 parts of divaricate saposhnikovia extracts, 15 to 20 parts of schizonepeta extracts, 15 to 20 parts of mulberry leaf extracts, 10 to 15 parts of green olive extracts and 20 to 25 parts of isatis root extracts. The compound pure natural granule for treating cold has the advantages that the goldenseal extracts and the echinacea extracts are added on the basis of relieving exterior syndromes, eliminating heat, clearing away the lung heat and relieving the sore throat of the conventional traditional Chinese medicine; meanwhile, the reinforced effects of inhibiting and killing viruses, cooling the blood, eliminating heat, resisting bacteria and diminishing inflammation can be achieved at the same time; the compound pure natural granule can be used for treating common cold and viral cold at the same time.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of compound pure natural cold electuary and preparation method thereof.
Background technology
Common Cold is multiple, regular incidence, the medicine for the treatment of flu except in, in addition to the mashed up related drugs of Western medicine, pure in
Medicine preparation is a big class, existing simple and clear traditional compatibility in pure Chinese medicinal preparation, and such as: QINGKAILING ZHUSHEJI, three essences are double yellow
Even oral liquid, Qingkailing granule, Radix Isatidis granule, YINQIAO granule, Xiao Chai Hu granules, infusion for treating coryza of wind cold type, FENGRE GANMAO KELI
Electuary, 999 GANMAO QINGRE KELI also have the multi-arch retaining structure of complexity, all from relieving the exterior syndrome with drugs of pungent in flavor and cool in nature heat clearing away, wind and heat dispersing, expelling wind and cold
Starting with, solve to have a headache and fever, the disease such as dry pharynx of coughing, systemic pain, rhinorrhea with clear discharge, Common Cold invades body except wind and cold,
Outside interference body normal energy metabolism, more or influenza virus invades and the disease resistance response of body.Chinese and Western combines not only
Only in terms of medical science, the mutual reference of pharmaceutical field is also the internal motivation promoting Development of Chinese Medicine.
The present invention is induced sweat at Chinese medicine, and heat radiation, lung heat clearing be antipyretic and on the basis of sore-throat relieving, increases the state-promulgated pharmacopoeia such as the U.S., France
The canada yellow-root extract included, this extract has antibacterial and anti-inflammation functions, is widely used in elimination respiratory inflammation in North America；Baphicacanthus cusia
Root bitter in the mouth is cold in nature, enters heart stomach warp, has effect of heat-clearing and toxic substances removing, sore-throat relieving, and root, stem extract are divided by limiting virus and play
The suppression killing action of infected by influenza and various bacteria is also had inhibitory action, and canada yellow-root coordinates, and can play and press down
System kills virus, and removing heat from blood is antipyretic, the invigoration effect of anti-inflammation；Echinacea is the most widely used genuine medicinal plants of the U.S.,
Effective ingredient contained by it can be by increasing leukocyte and T cell activity and the phagocytic activity of macrophage and enhancing body cell
Immunity, is uniquely to have " bone marrow preservation " effect in nature, significantly improves and safeguard the degree of depth immunity thing of autoimmune power
Matter, has exceeded well over existing transfer factor, interferon immune formulation the most, additionally has the effect such as antiviral, antiinflammatory, can
With flu-prevention, shorten Common Cold, alleviate laryngopharynx swelling and pain, mild or moderate infects, catch a cold, cough, influenza and other upper respiratory tract
Malaise symptoms, although it has been proposed that Echinacea can cause allergic reaction, but does not find relevant report clinically, and Xi'an is general
In the relevant extract quality standard of Lai Te biotech firm, explanation short-term is taken and is had safety.Additionally Radix Isatidis has detumescence, anti-
Allergy effect, under the conditions of control Echinacea extract dosage and Radix Isatidis share, the quality of the pharmaceutical preparations has safety, controllability.
Summary of the invention
The present invention provides a kind of compound pure natural cold electuary and preparation method thereof, the compound pure natural cold punching of the present invention
Agent is induced sweat at Chinese medicine, and heat radiation, lung heat clearing be antipyretic and on the basis of sore-throat relieving, increases canada yellow-root extract and Echinacea extract, profit
With Radix Isatidis, canada yellow-root and the synergistic function of Echinacea, can simultaneously work as suppression and kill virus, removing heat from blood is antipyretic, anti-
The invigoration effect of bacterium antiinflammatory, improves immunity of organisms, can treat Common Cold and viral influenza simultaneously.
In order to realize the object of the invention, adopt the following technical scheme that
A kind of compound pure natural cold electuary, the main component of described compound pure natural cold electuary includes by weight: north
U.S. Rhizoma Coptidis extract 20-25 part, Echinacea extract 8-10 part, Radix Saposhnikoviae extract 15-20 part, Herba Schizonepetae extract 15-20
Part, Folium Mori extract 15-20 part, Fructus Canarii extract 10-15 part, Radix Isatidis extract 20-25 part.
The preparation method of described compound pure natural cold electuary, it is characterised in that according to extract mixtures: starch:
Dextrin: each component is mixed by the part by weight of microcrystalline Cellulose=5 252, adds binding agent, correctives protein sugar, wet method system
Grain, after drying, utilizes oscillating granulator to carry out 10 mesh sieve granulate, and last Fresco Bag is packed.
Described binding agent is 3%(W/W) PVP ethanol solution；The addition of described protein sugar is 0.01-0.2%(W/W).
Advantages of the present invention and beneficial effect:
1) present invention is induced sweat at Chinese medicine, and heat radiation, lung heat clearing be antipyretic and on the basis of sore-throat relieving, increases the state-promulgated pharmacopoeia receipts such as the U.S., France
The canada yellow-root extract of record, this extract has antibacterial and anti-inflammation functions, is widely used in elimination respiratory inflammation in North America；Radix Isatidis
Bitter in the mouth is cold in nature, enters heart stomach warp, has effect of heat-clearing and toxic substances removing, sore-throat relieving, root, stem extract divided by limiting virus and play right
The suppression killing action of influenza virus and various bacteria is also had inhibitory action, and canada yellow-root coordinates, and can play suppression
Killing virus, removing heat from blood is antipyretic, the invigoration effect of anti-inflammation, has significant cooperative effect；
2) Echinacea is the most widely used genuine medicinal plants of the U.S., effective ingredient contained by it can by increase leukocyte and
T cell activity and the phagocytic activity of macrophage and enhancing body cellular immunity, be uniquely to have in nature that " bone marrow is protected
Deposit " effect, significantly improve and safeguard the degree of depth immune material of autoimmune power, the most exceeded well over existing transfer because of
Son, interferon immune formulation, additionally have the effect such as antiviral, antiinflammatory, can shorten Common Cold with flu-prevention, alleviate pharynx
Larynx swells and ache, mild or moderate infects, catch a cold, cough, influenza and other upper respiratory tract malaise symptoms；
3) Radix Isatidis has a detumescence, anti-allergic effects, under the conditions of controlling Echinacea extract dosage and Radix Isatidis share, and preparation
Quality has safety, controllability.
Specific embodiment
Below with specific embodiment, and the method describing in further detail with reference to data and the present invention being described, but this
Bright protection domain is not limited to the following example.
Embodiment 1
A kind of compound pure natural cold electuary, the main component of described compound pure natural cold electuary includes by weight: north
U.S. Rhizoma Coptidis extract 20 parts, Echinacea extract 8 parts, Radix Saposhnikoviae extract 15 parts, Herba Schizonepetae extract 15 parts, Folium Mori extract
15 parts, Fructus Canarii extract 10 parts, Radix Isatidis extract 20 parts.
The preparation method of described compound pure natural cold electuary, it is characterised in that according to extract: starch: dextrin: micro-
Each component is mixed by the part by weight of crystalline cellulose=5 252, adds binding agent, correctives protein sugar, wet granulation, is dried
After, utilize oscillating granulator to carry out 10 mesh sieve granulate, last Fresco Bag is packed.
Described binding agent is 3%(W/W) PVP ethanol solution；The addition of described protein sugar is 0.01%(W/W).
Embodiment 2
A kind of compound pure natural cold electuary, the main component of described compound pure natural cold electuary includes by weight: north
U.S. Rhizoma Coptidis extract 22 parts, Echinacea extract 9 parts, Radix Saposhnikoviae extract 18 parts, Herba Schizonepetae extract 17 parts, Folium Mori extract
17 parts, Fructus Canarii extract 12 parts, Radix Isatidis extract 22 parts.
The preparation method of described compound pure natural cold electuary, it is characterised in that according to extract: starch: dextrin: micro-
Each component is mixed by the part by weight of crystalline cellulose=5 252, adds binding agent, correctives protein sugar, wet granulation, is dried
After, utilize oscillating granulator to carry out 10 mesh sieve granulate, last Fresco Bag is packed.
Described binding agent is 3%(W/W) PVP ethanol solution；The addition of described protein sugar is 0.1%(W/W).
Embodiment 3
A kind of compound pure natural cold electuary, the main component of described compound pure natural cold electuary includes by weight: north
U.S. Rhizoma Coptidis extract 25 parts, Echinacea extract 10 parts, Radix Saposhnikoviae extract 20 parts, Herba Schizonepetae extract 20 parts, Folium Mori extract
20 parts, Fructus Canarii extract 15 parts, Radix Isatidis extract 25 parts.
The preparation method of described compound pure natural cold electuary, it is characterised in that according to extract: starch: dextrin: micro-
Each component is mixed by the part by weight of crystalline cellulose=5 252, adds binding agent, correctives protein sugar, wet granulation, is dried
After, utilize oscillating granulator to carry out 10 mesh sieve granulate, last Fresco Bag is packed.
Described binding agent is 3%(W/W) PVP ethanol solution；The addition of described protein sugar is 0.2%(W/W).
Modeling mice take medicine after in 2-3 days, can effectively slow down cold symptoms, stop stream thin nasal discharge, temperature is without on significance
Rising, energy i (in vivo) recovers, and without anaphylactic reaction, total effective rate is more than 90%；For the cure rate of viral influenza be 95% with
On.
Above are only presently preferred embodiments of the present invention, but the design of the present invention is not limited thereto with design.Fan Yibenfa
Equalization change and the modification that bright claim is done, comes under the behavior invading scope.
Claims (3)
1. a compound pure natural cold electuary, it is characterised in that the main component of described compound pure natural cold electuary is by weight
Amount part meter includes: canada yellow-root extract 20-25 part, Echinacea extract 8-10 part, Radix Saposhnikoviae extract 15-20 part, chaste tree
Mustard extract 15-20 part, Folium Mori extract 15-20 part, Fructus Canarii extract 10-15 part, Radix Isatidis extract 20-25
Part.
2. the preparation method of a compound pure natural cold electuary as claimed in claim 1, it is characterised in that according to extract
Mixture: starch: dextrin: each component is mixed by the part by weight of microcrystalline Cellulose=5 252, adds binding agent, correctives egg
White sugar, wet granulation, after drying, utilize oscillating granulator to carry out 10 mesh sieve granulate, last Fresco Bag is packed.
The preparation method of compound pure natural cold electuary the most according to claim 2, it is characterised in that described binding agent is
3%(W/W) PVP ethanol solution；The addition of described protein sugar is 0.01-0.2%(W/W).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610860909.3A CN106309596A (en) | 2016-09-29 | 2016-09-29 | Compound pure natural granule for treating cold and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610860909.3A CN106309596A (en) | 2016-09-29 | 2016-09-29 | Compound pure natural granule for treating cold and preparation method thereof |
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| Publication Number | Publication Date |
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| CN106309596A true CN106309596A (en) | 2017-01-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610860909.3A Pending CN106309596A (en) | 2016-09-29 | 2016-09-29 | Compound pure natural granule for treating cold and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021259441A1 (en) * | 2020-06-21 | 2021-12-30 | Khalil Ibrahim Taha Ibrahim | A new and safe pharmaceutical preparation for prophylaxis and treatment of respiratory viral infections, especially corona viruses |
-
2016
- 2016-09-29 CN CN201610860909.3A patent/CN106309596A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021259441A1 (en) * | 2020-06-21 | 2021-12-30 | Khalil Ibrahim Taha Ibrahim | A new and safe pharmaceutical preparation for prophylaxis and treatment of respiratory viral infections, especially corona viruses |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170111 |
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