CN1733141A - New preparation for curing chloasma and acne - Google Patents
New preparation for curing chloasma and acne Download PDFInfo
- Publication number
- CN1733141A CN1733141A CN 200510032022 CN200510032022A CN1733141A CN 1733141 A CN1733141 A CN 1733141A CN 200510032022 CN200510032022 CN 200510032022 CN 200510032022 A CN200510032022 A CN 200510032022A CN 1733141 A CN1733141 A CN 1733141A
- Authority
- CN
- China
- Prior art keywords
- radix
- gained
- adds
- time
- volatile oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 11
- 206010008570 Chloasma Diseases 0.000 title claims abstract description 11
- 208000003351 Melanosis Diseases 0.000 title claims abstract description 11
- 206010000496 acne Diseases 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 title abstract description 3
- 239000008187 granular material Substances 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims abstract description 10
- 239000006187 pill Substances 0.000 claims abstract description 8
- 239000007901 soft capsule Substances 0.000 claims abstract description 7
- 239000000284 extract Substances 0.000 claims description 26
- 239000000843 powder Substances 0.000 claims description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
- 239000000341 volatile oil Substances 0.000 claims description 24
- 238000000605 extraction Methods 0.000 claims description 23
- 239000000203 mixture Substances 0.000 claims description 19
- 235000005956 Cosmos caudatus Nutrition 0.000 claims description 18
- 244000293323 Cosmos caudatus Species 0.000 claims description 18
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 18
- 238000010992 reflux Methods 0.000 claims description 18
- 241000628997 Flos Species 0.000 claims description 16
- 239000009636 Huang Qi Substances 0.000 claims description 16
- 239000003814 drug Substances 0.000 claims description 15
- 239000000243 solution Substances 0.000 claims description 13
- 238000002156 mixing Methods 0.000 claims description 12
- 150000001875 compounds Chemical class 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 10
- 238000009472 formulation Methods 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 8
- 239000007864 aqueous solution Substances 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- 238000001256 steam distillation Methods 0.000 claims description 5
- 229920000858 Cyclodextrin Polymers 0.000 claims description 4
- 239000001116 FEMA 4028 Substances 0.000 claims description 4
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 4
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims description 4
- 229960004853 betadex Drugs 0.000 claims description 4
- 239000003921 oil Substances 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 abstract description 5
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 241001165494 Rhodiola Species 0.000 abstract 1
- 241000208422 Rhododendron Species 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000002775 capsule Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 240000005319 Sedum acre Species 0.000 description 3
- 235000014327 Sedum acre Nutrition 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 235000014666 liquid concentrate Nutrition 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
Disclosed is a novel preparation for curing chloasma and acne, wherein the constituents include (by weight ratio): rhodiola root, Chinese angelica root, azalea each 10-15%, wolferry fruit, astragalus root, processed fleece-flower root each 15-20%, safflower 4-5%, pearl 5-7%, and can be prepared into the dosage forms of granules, pills, soft capsules, and oral liquids.
Description
Technical field:
The present invention relates to a kind of novel formulation that is used for the treatment of chloasma, acne, particularly its function cures mainly and is blood-activating and qi-promoting, treating chloasma and acne.The chloasma, the remedy of acne that are used for caused by energy stagnation and blood stasis; It is that medicine composition and percentage by weight thereof are: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, novel forms such as the granule made of Flos Carthami 4～5%, Margarita 5～7%, pill, soft capsule, oral liquid.
Background technology:
What the present invention selected is some novel forms commonly used, according to the relevant laws and regulations of China's drug control, changes dosage form and manages as new drug research.Former dosage form has the stonecrop spot removal capsule, the national drug standards have been listed in, it is the Chinese medicinal capsule agent that main medicine composition is Radix Rhodiolae, Fructus Lycii, the Radix Astragali, Radix Angelicae Sinensis, Radix Polygoni Multiflori, Flos Carthami, Margarita, Folium Rhododendri Simsii, it is with crushing pearl in the prescription, Radix Rhodiolae, Radix Polygoni Multiflori, Radix Angelicae Sinensis alcohol extraction, Flos Carthami, Folium Rhododendri Simsii are carried volatile oil earlier, medicinal residues and Fructus Lycii, the Radix Astragali merge and decoct with water that extractions, medicinal liquid concentrate, drying, pulverize, add volatile oil, incapsulate, that is, the stonecrop spot removal capsule is used for the treatment of chloasma, acne.
The existing capsular volatile oil ingredient stability of stonecrop spot removal is relatively poor, the production cost height, and storage is inconvenient.Have the shortcoming that influences drug quality based on capsule, we use the modern pharmaceutical technology this product technology are done necessary improvement, make new pharmaceutical dosage form, guarantee the quality of product, improve drug effect, benefit the common people.
Summary of the invention:
The purpose of this invention is to provide a kind of can the assurance better and reduce production costs stability of drug, be beneficial to storage, the novel formulation that is used for the treatment of chloasma, acne, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is the novel formulation after dosage form is improved, and is the novel formulation that is used for the treatment of chloasma, acne, and its preparation method is:
(1) get it filled thing composition and percentage by weight thereof is: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, Flos Carthami 4～5%, Margarita 5～7%;
(2) in the medicine of (1), get the fine powder that Margarita powder was broken into 40～400 mesh sieves, standby, the best fine powder that was broken into 200～400 mesh sieves for superfine powder;
(3) in the medicine of (1), get Radix Rhodiolae, Radix Polygoni Multiflori Preparata, Radix Angelicae Sinensis with 30%～90% alcohol heating reflux extraction 1～5 time, add 3～10 times of amount reflux, extract, each 1～4 hour at every turn; Optimised process extracts 3 times for adding 75% alcohol heating reflux, adds 6 times of amounts for the first time and extracts 3 hours, adds 4 times of amounts for the second time and extracts 2 hours, adds 4 times of amounts for the third time and extracts 1 hour;
(4) extracting solution with multiple extraction gained in (3) merges, and filters, and filtrate recycling ethanol gets solution;
(5) in the medicine of (1), get Flos Carthami, Folium Rhododendri Simsii is used the steam distillation distillating extracting oil, it is standby to collect volatile oil, or volatile oil is standby with beta-cyclodextrin inclusion compound, and aqueous solution device is in addition collected;
(6) above-mentioned (5) gained medicinal residues and Fructus Lycii, the Radix Astragali are merged, decoct with water and extract 1～5 time, add 5～15 times of water gagings at every turn and extracted each 1～4 hour; Optimised process extracts 3 times for decocting with water, and adds 8 times of water gagings the first time and decocts extraction 3 hours, adds 6 times of water gagings for the second time and decocts extraction 2 hours, adds 6 times of water gagings for the third time and decocts extraction 1 hour;
(7) extracting solution with multiple extraction gained in (6) merges, and filters;
(8) aqueous solution with (4), (5), (7) gained merges, and being evaporated to relative density is the thick paste of 1.10～1.40 (40～70 ℃); Best for being concentrated into the thick paste that relative density is 1.30～1.35 (50 ℃);
(9) with above-mentioned (2) gained fine powder, add in the thick paste of (8) gained, mixing adds right amount of auxiliary materials, granulates, and drying adds (5) gained volatile oil or volatile oil clathrate compound, promptly gets granule;
(10), add in the thick paste of (8) gained mixing with above-mentioned (2) gained fine powder, drying is ground into fine powder, adds (5) gained volatile oil or volatile oil clathrate compound, mixing adopts common process, and it can further make novel forms such as pill, soft capsule, oral liquid.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of novel formulation that is used for the treatment of chloasma, acne, it is that medicine composition and percentage by weight thereof are: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, novel forms such as the granule made of Flos Carthami 4～5%, Margarita 5～7%, pill, soft capsule, oral liquid.
Embodiment 1
(1) get it filled thing composition and percentage by weight thereof is: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, Flos Carthami 4～5%, Margarita 5～7%;
(2) above eight flavors, get Margarita powder and be broken into fine powder, Radix Rhodiolae, Radix Polygoni Multiflori, Radix Angelicae Sinensis extracts 3 times with 75% alcohol heating reflux, add for the first time 6 times of amount reflux, extract, 3 hours, add for the second time 4 times of amount reflux, extract, 2 hours, add 4 times of amount reflux, extract, 1 hour for the third time, merge extractive liquid,, filter, get solution, Flos Carthami behind the filtrate recycling ethanol, after Folium Rhododendri Simsii extremely use up with steam distillation collection volatile oil, it was standby with beta-cyclodextrin inclusion compound to get volatile oil, aqueous solution device is in addition collected, medicinal residues and Fructus Lycii, the Radix Astragali merges, and decocts with water to extract three times, adds 8 times of water gagings for the first time and decocts extraction 3 hours, add for the second time 6 times of water gagings and decoct extraction 2 hours, add 6 times of water gagings for the third time and decoct extraction 1 hour, collecting decoction filters, filtrate and above-mentioned solution merge, and being evaporated to relative density is the thick paste of 1.30～1.35 (50 ℃); Add above-mentioned Margarita powder and appropriate amount of auxiliary materials, mixing is granulated, and drying adds above-mentioned volatile oil clathrate compound, and mixing promptly gets granule.
Embodiment 2
(1) get it filled thing composition and percentage by weight thereof is: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, Flos Carthami 4～5%, Margarita 5～7%;
(2) above eight flavors, get Margarita powder and be broken into fine powder, Radix Rhodiolae, Radix Polygoni Multiflori, Radix Angelicae Sinensis extracts 3 times with 75% alcohol heating reflux, add for the first time 6 times of amount reflux, extract, 3 hours, add for the second time 4 times of amount reflux, extract, 2 hours, add 4 times of amount reflux, extract, 1 hour for the third time, merge extractive liquid,, filter, get solution, Flos Carthami behind the filtrate recycling ethanol, after Folium Rhododendri Simsii extremely use up with steam distillation collection volatile oil, volatile oil was standby, aqueous solution device is in addition collected, medicinal residues and Fructus Lycii, the Radix Astragali merges, and decocts with water to extract three times, adds 8 times of water gagings for the first time and decocts extraction 3 hours, add for the second time 6 times of water gagings and decoct extraction 2 hours, add 6 times of water gagings for the third time and decoct extraction 1 hour, collecting decoction filters, filtrate and above-mentioned solution merge, and being evaporated to relative density is the thick paste of 1.30～1.35 (50 ℃); Add above-mentioned Margarita powder, mixing, drying is ground into fine powder, adds right amount of auxiliary materials, granulates, and drying adds above-mentioned volatile oil, and mixing is airtight, and packing promptly gets granule.
Embodiment 3
(1) get it filled thing composition and percentage by weight thereof is: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, Flos Carthami 4～5%, Margarita 5～7%;
(2) above eight flavors, get Margarita powder and be broken into fine powder, Radix Rhodiolae, Radix Polygoni Multiflori, Radix Angelicae Sinensis extracts 3 times with 75% alcohol heating reflux, add for the first time 6 times of amount reflux, extract, 3 hours, add for the second time 4 times of amount reflux, extract, 2 hours, add 4 times of amount reflux, extract, 1 hour for the third time, merge extractive liquid,, filter, get solution, Flos Carthami behind the filtrate recycling ethanol, after Folium Rhododendri Simsii extremely use up with steam distillation collection volatile oil, it was standby with beta-cyclodextrin inclusion compound to get volatile oil, aqueous solution device is in addition collected, medicinal residues and Fructus Lycii, the Radix Astragali merges, and decocts with water to extract three times, adds 8 times of water gagings for the first time and decocts extraction 3 hours, add for the second time 6 times of water gagings and decoct extraction 2 hours, add 6 times of water gagings for the third time and decoct extraction 1 hour, collecting decoction filters, filtrate and above-mentioned solution merge, and being evaporated to relative density is the thick paste of 1.30～1.35 (50 ℃); Add above-mentioned Margarita powder, mixing, drying is ground into fine powder, adds right amount of auxiliary materials and above-mentioned volatile oil clathrate compound, the mixing pill, drying promptly gets pill.
Adopt common process, it can further make novel forms such as soft capsule, oral liquid.
Claims (3)
1, a kind of novel formulation that is used for the treatment of chloasma, acne, it is that medicine composition and percentage by weight thereof are: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, novel forms such as the granule made of Flos Carthami 4～5%, Margarita 5～7%, pill, soft capsule, oral liquid.
2,, it is characterized in that the optimum weight percentage ratio of its medicine composition is according to the novel formulation of claim 1: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 11.90%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 17.86%, Flos Carthami 4.76%, Margarita 5.96%.
3, according to the novel formulation of claim 1, it is characterized in that:
(1) get it filled thing composition and percentage by weight thereof is: Radix Rhodiolae, Radix Angelicae Sinensis, Folium Rhododendri Simsii each 10～15%, Fructus Lycii, the Radix Astragali, Radix Polygoni Multiflori Preparata each 15～20%, Flos Carthami 4～5%, Margarita 5～7%;
(2) in the medicine of (1), get the fine powder that Margarita powder was broken into 40～400 mesh sieves, standby, the best fine powder that was broken into 200～400 mesh sieves for superfine powder;
(3) in the medicine of (1), get Radix Rhodiolae, Radix Polygoni Multiflori Preparata, Radix Angelicae Sinensis with 30%～90% alcohol heating reflux extraction 1～5 time, add 3～10 times of amount reflux, extract, each 1～4 hour at every turn; Optimised process extracts 3 times for adding 75% alcohol heating reflux, adds 6 times of amounts for the first time and extracts 3 hours, adds 4 times of amounts for the second time and extracts 2 hours, adds 4 times of amounts for the third time and extracts 1 hour;
(4) extracting solution with multiple extraction gained in (3) merges, and filters, and filtrate recycling ethanol gets solution;
(5) in the medicine of (1), get Flos Carthami, Folium Rhododendri Simsii is used the steam distillation distillating extracting oil, it is standby to collect volatile oil, or volatile oil is standby with beta-cyclodextrin inclusion compound, and aqueous solution device is in addition collected;
(6) above-mentioned (5) gained medicinal residues and Fructus Lycii, the Radix Astragali are merged, decoct with water and extract 1～5 time, add 5～15 times of water gagings at every turn and extracted each 1～4 hour; Optimised process extracts 3 times for decocting with water, and adds 8 times of water gagings the first time and decocts extraction 3 hours, adds 6 times of water gagings for the second time and decocts extraction 2 hours, adds 6 times of water gagings for the third time and decocts extraction 1 hour;
(7) extracting solution with multiple extraction gained in (6) merges, and filters;
(8) aqueous solution with (4), (5), (7) gained merges, and being evaporated to relative density is the thick paste of 1.10～1.40 (40～70 ℃); Best for being concentrated into the thick paste that relative density is 1.30～1.35 (50 ℃);
(9) with above-mentioned (2) gained fine powder, add in the thick paste of (8) gained, mixing adds right amount of auxiliary materials, granulates, and drying adds (5) gained volatile oil or volatile oil clathrate compound, promptly gets granule;
(10), add in the thick paste of (8) gained mixing with above-mentioned (2) gained fine powder, drying is ground into fine powder, adds (5) gained volatile oil or volatile oil clathrate compound, mixing adopts common process, and it can further make novel forms such as pill, soft capsule, oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510032022 CN1733141A (en) | 2005-08-17 | 2005-08-17 | New preparation for curing chloasma and acne |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510032022 CN1733141A (en) | 2005-08-17 | 2005-08-17 | New preparation for curing chloasma and acne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1733141A true CN1733141A (en) | 2006-02-15 |
Family
ID=36075896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510032022 Pending CN1733141A (en) | 2005-08-17 | 2005-08-17 | New preparation for curing chloasma and acne |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1733141A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689240A (en) * | 2015-03-18 | 2015-06-10 | 王竞鹏 | Medicine for treating Qi-stagnation and blood stasis type chloasma and preparation method thereof |
| CN109303758A (en) * | 2018-11-21 | 2019-02-05 | 青海晶珠藏药高新技术产业股份有限公司 | A kind of preparation method of skin maintenance and cosmetic benefits freckle-diminishing capsule |
| CN112656737A (en) * | 2021-01-28 | 2021-04-16 | 赵如意 | Plant acne-removing composition, preparation and preparation method thereof |
-
2005
- 2005-08-17 CN CN 200510032022 patent/CN1733141A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104689240A (en) * | 2015-03-18 | 2015-06-10 | 王竞鹏 | Medicine for treating Qi-stagnation and blood stasis type chloasma and preparation method thereof |
| CN109303758A (en) * | 2018-11-21 | 2019-02-05 | 青海晶珠藏药高新技术产业股份有限公司 | A kind of preparation method of skin maintenance and cosmetic benefits freckle-diminishing capsule |
| CN114288231A (en) * | 2018-11-21 | 2022-04-08 | 青海晶珠藏药高新技术产业股份有限公司 | Preparation method of capsule for beautifying and removing freckles |
| CN112656737A (en) * | 2021-01-28 | 2021-04-16 | 赵如意 | Plant acne-removing composition, preparation and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1748745A (en) | Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method | |
| CN1762480A (en) | Medicated leaven formulation and its preparation method | |
| CN1733141A (en) | New preparation for curing chloasma and acne | |
| CN1823925A (en) | New preparation for treating constrained liver qi | |
| CN1736449A (en) | Powder for climacteric syndrome and its preparing process | |
| CN1823885A (en) | New preparation used for treating puerperal galactozemia | |
| CN1698708A (en) | Leucorrhea disease treatment capsule and its preparation method | |
| CN1698855A (en) | Powder with ass-hide glue and Chinese angelica root and its preparation method | |
| CN1166397C (en) | Medicine for treating cardiovascular and cerebrovascular system disease, apoplectic sequel | |
| CN1583056A (en) | Gastrodia tuber and fleece-flower root preparation and its preparing method | |
| CN1733206A (en) | Chinese traditional medicine preparation for curing mastoplasia | |
| CN1292272A (en) | Medicine for curing diabetes and its preparation method | |
| CN1823981A (en) | New preparation for treating obesity | |
| CN1593531A (en) | Angelica and herbaceous peony root contained capsule for regulating menstruation and its preparation process | |
| CN1600359A (en) | Capsule for curing high blood fat and preparation method | |
| CN1593603A (en) | Emmeniopathy treating Chinese medicinal capsule and its preparation | |
| CN1733191A (en) | Capsule for warming uterus and promoting pregnancy and process for preparing the same | |
| CN1593606A (en) | Cold treating Chinese medicinal capsule and its preparation | |
| CN1596962A (en) | Capsule for treating hemorrhoid inflammation and its preparation method | |
| CN103623052A (en) | Novel method for preparing danxiang (Chinese character) rhinitis tablet | |
| CN1593604A (en) | Dispersible tablet for treating mammary glands hyperplasia and its preparing method | |
| CN1759867A (en) | Granules of Chinese traditional medicine for treating women's irregular menses | |
| CN1296073C (en) | Method for preparing a gynecopathy treating medicine | |
| CN1709359A (en) | Tablet for treating women's pelvic inflammation and its preparing method | |
| CN1456236A (en) | Preparation of woman effervescent tablets |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| PB01 | Publication | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20051209 Address after: Xinqiao village, Mawangdui Township, Changsha suburbs Applicant after: Shuai Yu Address before: No. seven, 20 Mile Road, Chenzhou, Hunan, Chenzhou, Hunan, China Applicant before: Huang Kaiqi |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |