CN103623052A - Novel method for preparing danxiang (Chinese character) rhinitis tablet - Google Patents
Novel method for preparing danxiang (Chinese character) rhinitis tablet Download PDFInfo
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- CN103623052A CN103623052A CN201310469964.6A CN201310469964A CN103623052A CN 103623052 A CN103623052 A CN 103623052A CN 201310469964 A CN201310469964 A CN 201310469964A CN 103623052 A CN103623052 A CN 103623052A
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- mentholum
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Abstract
The invention provides a novel method for preparing a danxiang (Chinese character) rhinitis tablet. Essential oil is extracted from pogostemon cablin and centipeda minima in the traditional prescription by virtue of a steam distillation method, and the residue is subjected to ethanol extraction. By adopting the novel technology, alcohol-soluble active ingredients are reserved, extracted volatile active ingredients are increased, loss of the effective ingredients is reduced, and the curative effect of the product is improved.
Description
Technical field
The present invention relates to Chinese medicine formulation art, is a kind of new technology of preparing Chinese medicine.
Background technology
The fragrant rhinitis tablet of gallbladder is the product that Jilin ten thousand logical Pharmaceutical Mei He Pharmaceutical limited company produces, and has antiinflammatory heat clearing away, expelling wind and cold, the effect of understand things pain-stopping.What its method for making adopted is that the 4th standard No. of recording of ministry standard is: the standard of WS3-B-0795-91.Original prescription and method for making are as follows:
[prescription]
Porcine bile paste 15g Herba Pogostemonis 560g Radix Angelicae Dahuricae 560g
Fructus Xanthii 450g Herba Centipedae 375g Herba Schizonepetae 250g
Flos Lonicerae 250g Flos Chrysanthemi Indici 2 59g Mentholum 1.5g
[method for making]
Above nine tastes; except Mentholum, porcine bile paste; get Herba Centipedae 50g and be ground into fine powder, sieve, residue Herba Centipedae and all the other each medicines are according to percolation (17 pages of appendix) under fluid extract and extractum item; with 65% ethanol, be that solvent carries out percolation; the collection liquid of filtering, reclaims ethanol, filters; filtrate is condensed into thick paste; merge with porcine bile paste, dry, add Herba Centipedae powder and right amount of auxiliary materials; granulation; dry, Mentholum porphyrize and above-mentioned granule are mixed, be pressed into 1000; sugar coating, obtains.
Wherein, Herba Pogostemonis is the dry aerial parts of labiate Herba Pogostemonis Pogostemon cablin (Blanco) Benth., returns spleen, stomach, lung meridian, there is eliminating turbid pathogen with aromatics, appetizing preventing or arresting vomiting, delivers the effect of expelling summer-heat, for turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, heat-damp in summer asthenia, uncomfortable in chest easypro, cold-damp is closed summer-heat, stomachache is vomited and diarrhoea, nasosinusitis headache.Herba Pogostemonis mainly contains the volatile oil components such as α-patchoulene, β-patchoulene, Pogostone.By modern study, show, an effective constituent for Herba Pogostemonis is volatile oil and part alcohol extract.
Herba Centipedae is the dry herb of feverfew Herba Centipedae Centipeda minima (L.) A.Br.et Aschers., the effect with " dispersing wind-cold; clearing the nasal passage; cough-relieving; removing toxic substances ", Herba Centipedae mainly contains taraxasteryl palmitate, taraxasteryl acetate, Quercetin-3-methyl ester etc. and volatile oil.Wherein, volatile oil and ethanol extract partly have cough-relieving, eliminate the phlegm, antiasthmatic effect.
Summary of the invention
The invention provides a kind of new method of preparing the fragrant rhinitis tablet of gallbladder, the phase, positive beneficial effect was, the one, increased the proposition of Herba Pogostemonis and Herba Centipedae volatile effective component, and the 2nd, retained Herba Pogostemonis and Herba Centipedae alcohol dissolubility effective ingredient.The proposition amount that has increased on the whole the fragrant rhinitis tablet effective ingredient of gallbladder, has strengthened product curative effect.
[prescription]
Porcine bile paste 15g Herba Pogostemonis 560g Radix Angelicae Dahuricae 560g
Fructus Xanthii 450g Herba Centipedae 375g Herba Schizonepetae 250g
Flos Lonicerae 250g Flos Chrysanthemi Indici 2 59g Mentholum 1.5g
[method for making]
Above nine tastes, except Mentholum, porcine bile paste, get Herba Pogostemonis and Herba Centipedae and put respectively Multifunctional pot for extracting Chinese medicine employing extraction by steam distillation volatile oil, and volatile oil beta-cyclodextrin inclusion compound is standby; Medicinal residues and all the other medical materials, according to percolation under fluid extract and extractum item, are that solvent carries out percolation with 65% ethanol, collect the liquid of filtering; reclaim ethanol, filter, filtrate is condensed into thick paste; merge with porcine bile paste, dry, add two kinds of Benexate Hydrochlorides and right amount of auxiliary materials; granulation; dry, Mentholum porphyrize and above-mentioned granule are mixed, be pressed into 1000; coating, obtains.
Preparation of the present invention, comprises various types of pills, granule, capsule and suitable other dosage forms clinically.
Technique comparative illustration before and after improving:
In former technique, Herba Pogostemonis and Herba Centipedae are to be used as medicine after alcohol extraction, after improving, are steam distillation, extract volatile oil, residue alcohol extraction.Volatile oil is used as medicine after beta-cyclodextrin inclusion compound.
After above-mentioned improvement, not only increase the volatile oil component in medical material, also retained Alcohol soluble composition; In addition, volatile oil is used as medicine after enclose, has reduced the loss in preparation process, has improved generally the paste-forming rate of product, has increased curative effect of medication.
Claims (1)
1. a method of preparing the fragrant rhinitis tablet of gallbladder, its raw material medicament preparation method is as follows:
[prescription]
Porcine bile paste 15g Herba Pogostemonis 560g Radix Angelicae Dahuricae 560g
Fructus Xanthii 450g Herba Centipedae 375g Herba Schizonepetae 250g
Flos Lonicerae 250g Flos Chrysanthemi Indici 2 59g Mentholum 1.5g
[method for making]
Above nine tastes, except Mentholum, porcine bile paste, get Herba Pogostemonis and Herba Centipedae and put respectively Multifunctional pot for extracting Chinese medicine employing extraction by steam distillation volatile oil, and volatile oil beta-cyclodextrin inclusion compound is standby; Medicinal residues and all the other medical materials, according to percolation under fluid extract and extractum item, are that solvent carries out percolation with 65% ethanol, collect the liquid of filtering; reclaim ethanol, filter, filtrate is condensed into thick paste; merge with porcine bile paste, dry, add two kinds of Benexate Hydrochlorides and right amount of auxiliary materials; granulation; dry, Mentholum porphyrize and above-mentioned granule are mixed, be pressed into 1000; coating, obtains.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310469964.6A CN103623052A (en) | 2013-09-30 | 2013-09-30 | Novel method for preparing danxiang (Chinese character) rhinitis tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310469964.6A CN103623052A (en) | 2013-09-30 | 2013-09-30 | Novel method for preparing danxiang (Chinese character) rhinitis tablet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103623052A true CN103623052A (en) | 2014-03-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310469964.6A Pending CN103623052A (en) | 2013-09-30 | 2013-09-30 | Novel method for preparing danxiang (Chinese character) rhinitis tablet |
Country Status (1)
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| CN (1) | CN103623052A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906056A (en) * | 2015-05-15 | 2015-09-16 | 南方医科大学 | Rhinitis treating dispersible tablet and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1460492A (en) * | 2003-06-03 | 2003-12-10 | 广西亿康药业股份有限公司 | Chinese medicine preparation for curing acute and chronic rhinitis and its production method |
| CN102988480A (en) * | 2012-10-08 | 2013-03-27 | 卞毓平 | Method for preparing bile and patchouli rhinitis tablets and application |
-
2013
- 2013-09-30 CN CN201310469964.6A patent/CN103623052A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1460492A (en) * | 2003-06-03 | 2003-12-10 | 广西亿康药业股份有限公司 | Chinese medicine preparation for curing acute and chronic rhinitis and its production method |
| CN102988480A (en) * | 2012-10-08 | 2013-03-27 | 卞毓平 | Method for preparing bile and patchouli rhinitis tablets and application |
Non-Patent Citations (1)
| Title |
|---|
| 未知: "《http://wenku.baidu.com/link?url=pao4il--aupHJg4e9yxStqDvi4shdIaeXOr7dFiIvhNbc2w82J1gld1-BWv4IYNHdwYXxEIergBCTYnHnK30ZMznDPrT7dL4-iAcvKkf7lS》", 29 May 2013 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906056A (en) * | 2015-05-15 | 2015-09-16 | 南方医科大学 | Rhinitis treating dispersible tablet and preparation method thereof |
| CN104906056B (en) * | 2015-05-15 | 2018-06-05 | 南方医科大学 | It is a kind of to be used to treat dispersible tablet of rhinitis and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140312 |