CN1733191A - Capsule for warming uterus and promoting pregnancy and process for preparing the same - Google Patents
Capsule for warming uterus and promoting pregnancy and process for preparing the same Download PDFInfo
- Publication number
- CN1733191A CN1733191A CN 200510031985 CN200510031985A CN1733191A CN 1733191 A CN1733191 A CN 1733191A CN 200510031985 CN200510031985 CN 200510031985 CN 200510031985 A CN200510031985 A CN 200510031985A CN 1733191 A CN1733191 A CN 1733191A
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- Prior art keywords
- radix
- stir
- fry
- capsule
- pregnancy
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- 239000002775 capsule Substances 0.000 title claims abstract description 16
- 238000010792 warming Methods 0.000 title claims abstract description 14
- 230000035935 pregnancy Effects 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title abstract 2
- 210000004291 uterus Anatomy 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title description 2
- 238000002360 preparation method Methods 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 5
- 239000003814 drug Substances 0.000 claims description 20
- 108010052008 colla corii asini Proteins 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 12
- 235000021419 vinegar Nutrition 0.000 claims description 9
- 239000000052 vinegar Substances 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- 201000010099 disease Diseases 0.000 claims description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 2
- 239000000470 constituent Substances 0.000 abstract description 3
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 235000010894 Artemisia argyi Nutrition 0.000 abstract 1
- 241000234653 Cyperus Species 0.000 abstract 1
- 241000123589 Dipsacus Species 0.000 abstract 1
- 241000208688 Eucommia Species 0.000 abstract 1
- 108010010803 Gelatin Proteins 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 244000030166 artemisia Species 0.000 abstract 1
- 229920000159 gelatin Polymers 0.000 abstract 1
- 239000008273 gelatin Substances 0.000 abstract 1
- 235000019322 gelatine Nutrition 0.000 abstract 1
- 235000011852 gelatine desserts Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000002552 dosage form Substances 0.000 description 3
- 239000006187 pill Substances 0.000 description 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a capsule for warming uterus and promoting pregnancy and process for preparation, wherein the constituents include (by weight ratio): prepared rehmannia root 20-25%, nutgrass flatsedge rhizome and eucommia bark each 10-14%, Chinese angelica root, Ligusticum wallichii, Chinese mugwort leafmulberry leaf, dipsacus root each 7-11%, root of herbaceous peony, donkey-hide gelatin and baikal skullcap root each 5-7%. Its preparing process is also disclosed in the invention.
Description
Technical field:
The present invention relates to a kind of Chinese medicinal capsule agent and preparation technology's method thereof, relate in particular to Womb-warming pregnancy-aiding capsule and preparation method thereof.
Background technology:
Capsule is a kind of pharmaceutical dosage form commonly used, according to the relevant laws and regulations of China's drug control, changes dosage form and manages as new drug research.The original dosage form of this product is a pill, has listed the national drug standards in.
Existing Womb-warming pregnancy-aiding ball is that the medicine composition is the medicine pill of Radix Rehmanniae Preparata, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry), Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-fry), Radix Dipsaci, the Radix Paeoniae Alba (wine stir-fry), Colla Corii Asini, Radix Scutellariae, it be with part medical material in the prescription decoct with water extraction, after concentrating thick paste, add in the above-mentioned thick paste after the Colla Corii Asini heating molten, all the other pulverizing medicinal materials become fine powder to add mixing, pill, drying, polishing in the aforementioned thick paste, that is, the Womb-warming pregnancy-aiding ball is used for the treatment of women's disease that fails to be impregnated for a long time.
The production technology and the quality standard of existing Womb-warming pregnancy-aiding ball are simpler, are difficult to effectively control and ensure drug quality, and the disintegrate onset is fast not as capsule.
Summary of the invention:
The purpose of this invention is to provide a kind of can effectively control and ensure drug quality, the disintegrate onset is faster, is used for the treatment of women's Chinese medicine preparation of disease and preparation method thereof that fails to be impregnated for a long time, and overcomes the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of Womb-warming pregnancy-aiding capsule, it is the Chinese patent medicine that a kind of women of treatment fails to be impregnated for a long time disease, it is that the medicine composition is a Radix Rehmanniae Preparata 20～25%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 10～14%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-fry), Radix Dipsaci each 7～11%, the Radix Paeoniae Alba (wine stir-frys), Colla Corii Asini, Radix Scutellariae be capsule of 5～7% respectively.
The optimum weight percentage ratio of medicine constituent is: Radix Rehmanniae Preparata 23.5%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 11.8%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-frys), Radix Dipsaci each 8.8%, the Radix Paeoniae Alba (wine stir-fry), Colla Corii Asini, Radix Scutellariae respectively 5.9%.
The capsular preparation method of Womb-warming pregnancy-aiding:
(1) get it filled thing composition and percentage by weight thereof is: Radix Rehmanniae Preparata 20～25%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 10～14%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-frys), Radix Dipsaci each 7～11%, the Radix Paeoniae Alba (wine stir-fry), Colla Corii Asini, Radix Scutellariae respectively 5～7%;
(2) in the medicine of (1), get the fine powder that Colla Corii Asini, Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Paeoniae Alba were ground into 40～200 mesh sieves; The best was the fine powder of 80～120 mesh sieves, and was standby;
(3) in the medicine of (1), get Radix Rehmanniae Preparata, the Cortex Eucommiae, Rhizoma Cyperi, Radix Dipsaci, Folium Artemisiae Argyi, Radix Scutellariae and decoct with water 1～3 time, add 4～16 times of water gagings at every turn and decocted 1～4 hour; Optimised process adds 10 times of water gagings for the first time and decocted 3 hours for decocting with water 2 times, adds 8 times of water gagings for the second time and decocts 2 hours;
(4) decocting liquid that repeatedly decocts gained in (3) is merged, filter;
(5) with the filtrate of (4) gained, being evaporated to relative density is the thick paste of 1.10～1.40 (60 ℃); Best for being concentrated into the thick paste that relative density is 1.35 (60 ℃);
(6) with the fine powder mixing of (2) gained, add in the thick paste of (5) gained, mixing is granulated, and drying incapsulates, promptly.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of Womb-warming pregnancy-aiding capsule, be the Chinese patent medicine that a kind of women of treatment fails to be impregnated for a long time disease, it is that the medicine composition is the capsule of Radix Rehmanniae Preparata, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry), Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-fry), Radix Dipsaci, the Radix Paeoniae Alba (wine stir-fry), Colla Corii Asini, Radix Scutellariae.
A kind of optimum implementation of Womb-warming pregnancy-aiding capsule preparation method thereof:
(1) get it filled thing constituent and optimum weight percentage ratio thereof is: Radix Rehmanniae Preparata 23.5%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 11.8%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-frys), Radix Dipsaci each 8.8%, the Radix Paeoniae Alba (wine stir-fry), Colla Corii Asini, Radix Scutellariae respectively 5.9%;
(2) in the above medicine, get Radix Rehmanniae Preparata, the Cortex Eucommiae, Rhizoma Cyperi, Radix Dipsaci, Folium Artemisiae Argyi, Radix Scutellariae and decoct with water secondary, add 10 times of water gagings for the first time and decocted 3 hours, add for the second time 8 times of water gagings and decocted 2 hours, collecting decoction filters, filtrate decompression is concentrated into the thick paste that relative density is 1.35 (60 ℃), and is standby; Colla Corii Asini, Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Paeoniae Alba were ground into the fine powder of 80～120 mesh sieves, added in the above-mentioned thick paste, granulated, and drying incapsulates, promptly.
Advantage of the present invention is: Nuangongyunzi Capsule is the new product that improves preparation technology and quality standard after formulation is improved, Be of great importance to guaranteeing and improving the quality of products, the present invention can bring into play the rapid-action spy of disintegration behind the drug administration fully Point is mainly used in treating women's disease that fails to be impregnated for a long time and can satisfies better the clinical treatment needs.
Claims (3)
1, a kind of Womb-warming pregnancy-aiding capsule, it is the Chinese patent medicine that a kind of women of being used for the treatment of fails to be impregnated for a long time disease, it is characterized in that it is that the medicine composition is a Radix Rehmanniae Preparata 20～25%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 10～14%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-fry), Radix Dipsaci each 7～11%, the Radix Paeoniae Alba (wine stir-frys), Colla Corii Asini, Radix Scutellariae be capsule of 5～7% respectively.
2, the capsular preparation method of a kind of Womb-warming pregnancy-aiding is characterized in that:
(1) get it filled thing composition and percentage by weight thereof is: Radix Rehmanniae Preparata 20～25%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 10～14%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-frys), Radix Dipsaci each 7～11%, the Radix Paeoniae Alba (wine stir-fry), Colla Corii Asini, Radix Scutellariae respectively 5～7%;
(2) in the medicine of (1), get the fine powder that Colla Corii Asini, Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Paeoniae Alba were ground into 40～200 mesh sieves; The best was the fine powder of 80～120 mesh sieves, and was standby;
(3) in the medicine of (1), get Radix Rehmanniae Preparata, the Cortex Eucommiae, Rhizoma Cyperi, Radix Dipsaci, Folium Artemisiae Argyi, Radix Scutellariae and decoct with water 1～3 time, add 4～16 times of water gagings at every turn and decocted 1～4 hour; Optimised process adds 10 times of water gagings for the first time and decocted 3 hours for decocting with water 2 times, adds 8 times of water gagings for the second time and decocts 2 hours;
(4) decocting liquid that repeatedly decocts gained in (3) is merged, filter;
(5) with the filtrate of (4) gained, being evaporated to relative density is the thick paste of 1.10～1.40 (60 ℃); Best for being concentrated into the thick paste that relative density is 1.35 (60 ℃);
(6) with the fine powder mixing of (2) gained, add in the thick paste of (5) gained, mixing is granulated, and drying incapsulates, promptly.
3, Womb-warming pregnancy-aiding capsule according to claim 1, the optimum weight percentage ratio that it is characterized in that its medicine composition is Radix Rehmanniae Preparata 23.5%, Rhizoma Cyperi (processed with vinegar), the Cortex Eucommiae (stir-fry) each 11.8%, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Folium Artemisiae Argyi (stir-fry), Radix Dipsaci each 8.8%, the Radix Paeoniae Alba (wine stir-frys), Colla Corii Asini, Radix Scutellariae respectively 5.9%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510031985 CN1733191A (en) | 2005-08-08 | 2005-08-08 | Capsule for warming uterus and promoting pregnancy and process for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510031985 CN1733191A (en) | 2005-08-08 | 2005-08-08 | Capsule for warming uterus and promoting pregnancy and process for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1733191A true CN1733191A (en) | 2006-02-15 |
Family
ID=36075946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510031985 Pending CN1733191A (en) | 2005-08-08 | 2005-08-08 | Capsule for warming uterus and promoting pregnancy and process for preparing the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1733191A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101428106B (en) * | 2008-12-24 | 2011-05-25 | 张铎 | Medicament composition for treating female infertility, and uses thereof |
| CN106139097A (en) * | 2016-08-19 | 2016-11-23 | 林力 | Dispel cold in warm palace, regulating menstruation Traditional Chinese medicine for steeping foot formula |
-
2005
- 2005-08-08 CN CN 200510031985 patent/CN1733191A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101428106B (en) * | 2008-12-24 | 2011-05-25 | 张铎 | Medicament composition for treating female infertility, and uses thereof |
| CN106139097A (en) * | 2016-08-19 | 2016-11-23 | 林力 | Dispel cold in warm palace, regulating menstruation Traditional Chinese medicine for steeping foot formula |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| PB01 | Publication | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20051202 Address after: Xinqiao village, Mawangdui Township, Changsha City, Hunan Applicant after: Shi Yu Address before: No. seven, 20 Mile Road, Chenzhou, Hunan, Chenzhou, Hunan, China Applicant before: Huang Kaiqi |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |