CN1733140A - New preparation for curing diseases of qi deficiency and blood insufficiency - Google Patents
New preparation for curing diseases of qi deficiency and blood insufficiency Download PDFInfo
- Publication number
- CN1733140A CN1733140A CN 200510032021 CN200510032021A CN1733140A CN 1733140 A CN1733140 A CN 1733140A CN 200510032021 CN200510032021 CN 200510032021 CN 200510032021 A CN200510032021 A CN 200510032021A CN 1733140 A CN1733140 A CN 1733140A
- Authority
- CN
- China
- Prior art keywords
- radix
- fructus lycii
- water
- gained
- corii asini
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008280 blood Substances 0.000 title claims abstract description 11
- 210000004369 blood Anatomy 0.000 title claims abstract description 11
- 230000007812 deficiency Effects 0.000 title claims abstract description 10
- 201000010099 disease Diseases 0.000 title claims abstract description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 8
- 238000002360 preparation method Methods 0.000 title abstract description 4
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 21
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 21
- 235000008434 ginseng Nutrition 0.000 claims abstract description 21
- 239000008187 granular material Substances 0.000 claims abstract description 10
- 239000007788 liquid Substances 0.000 claims abstract description 7
- 239000006187 pill Substances 0.000 claims abstract description 7
- 239000007901 soft capsule Substances 0.000 claims abstract description 7
- 239000006188 syrup Substances 0.000 claims abstract description 7
- 235000020357 syrup Nutrition 0.000 claims abstract description 7
- 239000003826 tablet Substances 0.000 claims abstract description 6
- 241000208340 Araliaceae Species 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 18
- 108010052008 colla corii asini Proteins 0.000 claims description 16
- 241000756943 Codonopsis Species 0.000 claims description 15
- 239000009636 Huang Qi Substances 0.000 claims description 15
- 239000000843 powder Substances 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 238000009472 formulation Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 6
- 239000012567 medical material Substances 0.000 claims description 5
- 230000006837 decompression Effects 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 239000000706 filtrate Substances 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 2
- 238000000605 extraction Methods 0.000 claims description 2
- 108010010803 Gelatin Proteins 0.000 abstract description 3
- 229920000159 gelatin Polymers 0.000 abstract description 3
- 239000008273 gelatin Substances 0.000 abstract description 3
- 235000019322 gelatine Nutrition 0.000 abstract description 3
- 235000011852 gelatine desserts Nutrition 0.000 abstract description 3
- 244000241838 Lycium barbarum Species 0.000 abstract 1
- 235000015459 Lycium barbarum Nutrition 0.000 abstract 1
- 235000015468 Lycium chinense Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000002775 capsule Substances 0.000 description 5
- 239000002552 dosage form Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 3
- 235000021286 stilbenes Nutrition 0.000 description 3
- 206010003549 asthenia Diseases 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000021551 crystal sugar Nutrition 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
Disclosed is a novel medicinal preparation for treating diseases of qi deficiency and blood insufficiency, wherein the constituents include (by weight ratio): root of pilose asiabell 48-52%, wolfberry fruit 28-31%, astragalus root 16-19%, donkey-hide gelatin 2-4%, ginseng 0.1-0.5%. The preparation can be made into granule, tablet, pill, soft capsule, oral liquid and syrup.
Description
Technical field:
The present invention relates to a kind of novel formulation for the treatment of diseases of qi deficiency and blood insufficiency, particularly its function and cure mainly and be QI invigorating, nourish blood.Be used for Qi and blood deficiency, eipathia asthenia; It is that medicine composition and percentage by weight thereof are: granule, tablet, pill, soft capsule, oral liquid, syrup that Radix Codonopsis 48～52%, Fructus Lycii 28～31%, the Radix Astragali 16～19%, Colla Corii Asini 2～4%, Radix Ginseng 0.1～0.5% are made.
Background technology:
What the present invention selected is some novel forms commonly used, according to the relevant laws and regulations of China's drug control, changes dosage form and manages as new drug research.The existing ginseng of former dosage form stilbene Colla Corii Asini capsule, the national drug standards have been listed in, it is the Chinese medicinal capsule agent that main medicine composition is Radix Codonopsis, Fructus Lycii, the Radix Astragali, Radix Ginseng, Colla Corii Asini, it is that Radix Ginseng in the prescription is pulverized, and Radix Codonopsis, Fructus Lycii, the Radix Astragali decoct with water extraction, add the crystal sugar dissolving, add Colla Corii Asini and dissolve, concentrating the back adds aforementioned medical material fine powder mixing, oven dry, pulverizes, incapsulates, that is, ginseng stilbene Colla Corii Asini capsule is used for the treatment of Qi and blood deficiency, eipathia asthenia.
The medicine stability of existing ginseng stilbene Colla Corii Asini capsule is relatively poor, the production cost height, and storage is inconvenient.Have the shortcoming that influences drug quality based on capsule, we use the modern pharmaceutical technology this product technology are done necessary improvement, make new pharmaceutical dosage form, guarantee the quality of product, improve drug effect, benefit the common people.
Summary of the invention:
The purpose of this invention is to provide a kind of can the assurance better and reduce production costs stability of drug, be beneficial to storage, the novel formulation that is used for the treatment of diseases of qi deficiency and blood insufficiency, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is the novel formulation after dosage form is improved, and is the novel formulation that is used for the treatment of diseases of qi deficiency and blood insufficiency, and its preparation method is:
(1) get it filled thing composition and percentage by weight thereof is: Radix Codonopsis 48～52%, Fructus Lycii 28～31%, the Radix Astragali 16～19%, Colla Corii Asini 2～4%, Radix Ginseng 0.1～0.5%;
(2) in the medicine of (1), get the fine powder that the Radix Ginseng powder was broken into 40～200 mesh sieves, standby, the best was the fine powder of 80～120 mesh sieves;
(3) in the medicine of (1), get Radix Codonopsis, Fructus Lycii, the Radix Astragali and decoct with water and extract 1～5 time, add the water of 4～20 times of amounts of medical material at every turn, decoct and extracted each 1～3 hour; Optimised process extracts 3 times for decocting with water, and adds 8 times of water gagings for the first time, and second and third time respectively adds 6 times of water gagings, and each the decoction extracted 2 hours;
(4) extracting solution with multiple extraction gained in (3) merges, and filters;
(5) filtrate decompression with (4) gained is concentrated into the thick paste that relative density is 1.10～1.40 (60～90 ℃); Best for being concentrated into the thick paste that relative density is 1.25～1.35 (60～90 ℃);
(6) with above-mentioned (2) gained fine powder, add in the thick paste of (5) gained, behind the mix homogeneously, add right amount of auxiliary materials, to granulate, drying promptly gets granule, adopts common process, and it can further make tablet, pill, soft capsule, oral liquid, syrup.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
The novel formulation that is used for the treatment of diseases of qi deficiency and blood insufficiency, it is that medicine composition and percentage by weight thereof are: granule, tablet, pill, soft capsule, oral liquid, syrup that Radix Codonopsis 48～52%, Fructus Lycii 28～31%, the Radix Astragali 16～19%, Colla Corii Asini 2～4%, Radix Ginseng 0.1～0.5% are made.
Embodiment 1
Radix Codonopsis 425g Fructus Lycii 250g Radix Astragali 150g Radix Ginseng 3.5g Colla Corii Asini 25g
Above five tastes medical material, Radix Ginseng, Colla Corii Asini pulverize separately become fine powder; Radix Codonopsis, Fructus Lycii, the Radix Astragali decoct with water three times, and each 2 hours, collecting decoction filtered, and filtrate decompression is condensed into the thick paste of 1.28～1.32 (80 ℃), adds Radix Ginseng fine powder, donkey-hide gelatin fine powder and right amount of auxiliary materials, stirs evenly, and makes granule, promptly.
Embodiment 2
Radix Codonopsis 425g Fructus Lycii 250g Radix Astragali 150g Radix Ginseng 3. 5g Colla Corii Asini 25g
Above five tastes medical material, Radix Ginseng, Colla Corii Asini pulverize separately become fine powder; Radix Codonopsis, Fructus Lycii, the Radix Astragali decoct with water three times, and each 2 hours, collecting decoction filtered, and filtrate decompression is condensed into the thick paste of 1.28～1.32 (80 ℃), adds Radix Ginseng fine powder, donkey-hide gelatin fine powder and right amount of auxiliary materials, stirs evenly, and makes granule, tabletting, promptly.
Embodiment 3
Radix Codonopsis 425g Fructus Lycii 250g Radix Astragali 150g Radix Ginseng 3.5g Colla Corii Asini 25g
Adopt said method and common process, it can further make pill, soft capsule, oral liquid, syrup.
Claims (3)
1, a kind of novel formulation for the treatment of diseases of qi deficiency and blood insufficiency, it is that medicine composition and percentage by weight thereof are: granule, tablet, pill, soft capsule, oral liquid, syrup that Radix Codonopsis 48～52%, Fructus Lycii 28～31%, the Radix Astragali 16～19%, Colla Corii Asini 2～4%, Radix Ginseng 0.1～0.5% are made.
2,, it is characterized in that the optimum weight percentage ratio of its medicine composition is: Radix Codonopsis 49.85%, Fructus Lycii 29.33%, the Radix Astragali 17.60%, Colla Corii Asini 2.93%, Radix Ginseng 0.29% according to the novel formulation of claim 1.
3, according to the novel formulation of claim 1, it is characterized in that:
(1) get it filled thing composition and percentage by weight thereof is: Radix Codonopsis 48～52%, Fructus Lycii 28～31%, the Radix Astragali 16～19%, Colla Corii Asini 2～4%, Radix Ginseng 0.1～0.5%;
(2) in the medicine of (1), get the fine powder that the Radix Ginseng powder was broken into 40～200 mesh sieves, standby, the best was the fine powder of 80～120 mesh sieves;
(3) in the medicine of (1), get Radix Codonopsis, Fructus Lycii, the Radix Astragali and decoct with water and extract 1～5 time, add the water of 4～20 times of amounts of medical material at every turn, decoct and extracted each 1～3 hour; Optimised process extracts 3 times for decocting with water, and adds 8 times of water gagings for the first time, and second and third time respectively adds 6 times of water gagings, and each the decoction extracted 2 hours;
(4) extracting solution with multiple extraction gained in (3) merges, and filters;
(5) filtrate decompression with (4) gained is concentrated into the thick paste that relative density is 1.10～1.40 (60～90 ℃); Best for being concentrated into the thick paste that relative density is 1.25～1.35 (60～90 ℃);
(6) with above-mentioned (2) gained fine powder, add in the thick paste of (5) gained, behind the mix homogeneously, add right amount of auxiliary materials, to granulate, drying promptly gets granule, adopts common process, and it can further make tablet, pill, soft capsule, oral liquid, syrup.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510032021 CN1733140A (en) | 2005-08-17 | 2005-08-17 | New preparation for curing diseases of qi deficiency and blood insufficiency |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510032021 CN1733140A (en) | 2005-08-17 | 2005-08-17 | New preparation for curing diseases of qi deficiency and blood insufficiency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1733140A true CN1733140A (en) | 2006-02-15 |
Family
ID=36075895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510032021 Pending CN1733140A (en) | 2005-08-17 | 2005-08-17 | New preparation for curing diseases of qi deficiency and blood insufficiency |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1733140A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107007748A (en) * | 2017-05-24 | 2017-08-04 | 江苏宁康医疗器械有限公司 | Improve Chinese medicine composition, medicine of physically weak symptom and its preparation method and application |
| CN109793831A (en) * | 2017-11-17 | 2019-05-24 | 孙立民 | Ginseng and pilose antler qi and blood nourishing medicinal granules |
-
2005
- 2005-08-17 CN CN 200510032021 patent/CN1733140A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107007748A (en) * | 2017-05-24 | 2017-08-04 | 江苏宁康医疗器械有限公司 | Improve Chinese medicine composition, medicine of physically weak symptom and its preparation method and application |
| CN109793831A (en) * | 2017-11-17 | 2019-05-24 | 孙立民 | Ginseng and pilose antler qi and blood nourishing medicinal granules |
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| C06 | Publication | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| PB01 | Publication | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20051209 Address after: Xinqiao village, Mawangdui Township, Changsha suburbs Applicant after: Shuai Yu Address before: No. seven, 20 Mile Road, Chenzhou, Hunan, Chenzhou, Hunan, China Applicant before: Huang Kaiqi |
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| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |