CN1062154C - Method for producing Chinese patent medicine for curing diabetes and its pill - Google Patents

Method for producing Chinese patent medicine for curing diabetes and its pill Download PDF

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CN1062154C
CN1062154C CN96117548A CN96117548A CN1062154C CN 1062154 C CN1062154 C CN 1062154C CN 96117548 A CN96117548 A CN 96117548A CN 96117548 A CN96117548 A CN 96117548A CN 1062154 C CN1062154 C CN 1062154C
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radix
patent medicine
diabetes
pill
chinese patent
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CN1136954A (en
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潘端
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Abstract

The present invention belongs to a method for producing Chinese patent medicines and pills for treating diabetes. The Chinese patent medicine adjusts the medicine ingredients in the formula and a dosage proportion thereof aiming at the pathology characteristics of the diabetes relevant to the lung, the spleen, particularly kidney deficiency on the basis of an old prescription so as to overcome the defects of poor pertinence, deficiencies of nourishing Yin and benefiting Qi, poor treatment effect, etc. of the original prescription. Thus, the present invention has the efficiencies of nourishing Yin, benefiting Qi, invigorating the kidney, clearing heat, moistening the lung, quenching thirst, clearing the stomach, replenishing Yin, etc. The present invention is used for treating different diabetes, and the present invention has the function of improving the secretion and the synthesize of insulins and has the characteristics of rapid sugar reduction and lipid reduction, high treatment effect, no side effect, convenient storage of the prepared pills, quantitative dosage, etc.

Description

Control the production method of diabetes with Chinese patent medicine and pill thereof
The invention belongs to a kind of Chinese patent medicine and production method thereof, particularly a kind of Chinese medicine pill or capsule powder and pill production method that is used for the treatment of diabetes.
Diabetes are a kind of commonly encountered diseases healthy with harm humans, frequently-occurring diseases of having a strong impact on.Though have existed since ancient times (ancient times claims " diabetes ") for this disease, but development along with society, growth in the living standard particularly increases rapidly in the nearly prevalence of diabetes during the last ten years in many cities of developed country and China, is called " city killer's disease " by modern society.This disease is a kind of endocrinopathy, it is characterized in that insulin is relative or absolute not enough, blood glucose, glucose in urine and blood fat height; And be characterized by polydipsia, polyphagia, polyuria and become thin etc.Morbidity back is if can not get timely treatment, promptly can encroach on kidney and concurrent nephropathy etc. cause more serious consequence.Though the glyburide in the Western medicine has better curative effect to diabetes, side effect is bigger, and hypoglycemic reaction easily takes place, and gastrointestinal reaction causes leukopenia etc.; And " Fructus Lycii looses " that be used for the treatment of diabetes (diabetes) in the ancient proved recipe (sees " Chinese medicine dictionary " Shanghai People's Press, 1997 editions P1519, former side comes from Holy Benevolent Prescriptions), its basic prescription is: Fructus Lycii, Radix Ginseng (removing LU), Radix Angelicae Sinensis, Radix Paeoniae Alba each one or two, the Radix Astragali one two halves (file), Cortex Cinnamomi three minutes, smash sieve for loosing every clothes three money.This side's main effect is an enriching yin boost qi; Range of application: control chronic consumptive disease, deficiency of lower-JIAO wound, little thirsty, frequent micturition, and the card of diabetes diabetes due to kidney-deficiency.Though this proved recipe has certain therapeutical effect to diabetes, because its main effect is an enriching yin boost qi only, and the power of its enriching yin boost qi is inadequate for diabetes, therefore exists the specific aim of treatment relatively poor.Defectives such as effect is also undesirable.
The objective of the invention is on the basis of ancient proved recipe " Fructus Lycii looses ", at various pathology of Diabetes Mellitus feature, adjust its prescription, help the human righteousness to reach, strengthen the immune function of cell viability and body, improve the secretion of insulin complex functionality, rapidly purposes such as blood sugar lowering, blood fat reducing, raising treatment of diabetes effect.
Solution of the present invention is to cause because of the body deficiency of YIN, temperament and interest imbalance, labor desire are excessive etc. due to the endocrine disturbance according to diabetes systems.This disease is all relevant with lung, spleen, kidney, and is particularly relevant with deficiency of kidney-QI.Therefore, the present invention keeps Radix Ginseng, strengthens Fructus Lycii and the each dose of the Radix Astragali, and adopt the Rhizoma Dioscoreae with supplementing QI and nourishing YIN, tonifying the lung, spleen, kidney in former prescription; Clearing away heat and cooling blood, the Radix Rehmanniae of YIN nourishing and the production of body fluid promoting; The Radix Puerariae of clearing away heat and promoting production of body fluid; The Radix Scrophulariae of heat-clearing and toxic substances removing, yin nourishing; Promoting the production of body fluid to quench thirst, pathogenic fire reducing, moisturize, evacuation of pus, repercussive Radix Trichosanthis; The Rhizoma Polygonati of lung moistening YIN nourishing, invigorating the lung and benefiting vital QI; The Radix Notoginseng of the Fructus Crataegi of promoting digestion and removing stagnation, promoting blood circulation to remove blood stasis and removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation replaces Radix Angelicae Sinensis, Radix Paeoniae Alba and the Cortex Cinnamomi among the former side.Cause this side's pharmacology and basic effect to change to: benefiting qi and nourishing yin, the kidney invigorating, clearing heat and moistening lung, promoting the production of body fluid to quench thirst, clearing stomach yin nourishing.Render a service adaptability, the raising curative effect that reaches each paradiabetes to strengthen medication.In order to take and to preserve conveniently, the present invention also is made into pill and capsule except that can directly using the powder.Therefore, pill or capsule that patent medicine of the present invention is made up of Fructus Lycii, Radix Ginseng, the Radix Astragali, Rhizoma Dioscoreae, Radix Puerariae, Radix Trichosanthis, the Radix Rehmanniae, Radix Notoginseng, Fructus Crataegi, Radix Scrophulariae and Rhizoma Polygonati, also or powder, but with the above two for well; Weight ratio in the above-mentioned patent medicine between each composition, be respectively radix 1 with Fructus Lycii, the Radix Astragali, Rhizoma Dioscoreae, then Radix Ginseng, Radix Trichosanthis are respectively 0.40~0.46, and Radix Puerariae is 0.65~0.70, the Radix Rehmanniae, Fructus Crataegi, Rhizoma Polygonati are respectively 0.33~0.39, and Radix Notoginseng, Radix Scrophulariae are respectively 0.16~0.23.Radix Ginseng in the above-mentioned patent medicine also can adopt Radix Panacis Quinquefolii to replace, and usage ratio is constant.Because diabetics is avoided sugar, and can not adopt close ball.Thereby the production method of pill is among the present invention:
A. at first all mix in proportion or mix respectively to pulverize with acceptance(check) and through each crude drug of sterilization treatment and be smalls, it is stand-by to sieve;
B. slurrying liquid: in the ratio of Oryza glutinosa and water 1: 20~30, earlier it is boiled into the Oryza glutinosa juice, after filtration, after the cooling,, make serosity, stand-by by the ratio adding glycerol and the mix homogeneously of Oryza glutinosa juice weight 8~15%;
C. after the powder that whole powder that mix pulverizing among the A maybe will be mixed pulverizing respectively weighs up mixing by formula proportion again, add serosity, the rubbing pill as binding agent;
D. at last made pill is carried out dried, promptly make pill of the present invention.
Above-mentioned employing all mix to be pulverized in proportion or mixed the purpose of pulverizing respectively is to contain heavy the pulverizing separately or will be pie when milling as Fructus Lycii of sugar in order to overcome, and can not powdering, influence the patent medicine making of later stage operation; And Radix Rehmanniae Preparata, Radix Scrophulariae quality are soft, also are difficult for grinding or being ground into the disadvantage of smalls separately.
And capsule of the present invention, then be be mixed in proportion after the pulverizing powder directly metering pack in the conventional capsule.
The present invention is owing to strengthened Fructus Lycii and the absolute dosage of the Radix Astragali in prescription exponentially at every turn in prescription and in taking; Adopt Rhizoma Dioscoreae, the Radix Rehmanniae etc. eight flavor medicines to replace Radix Angelicae Sinensis, Radix Paeoniae Alba and Cortex Cinnamomi in the former prescription simultaneously, make it not only have the effect of enriching yin boost qi, but also have effects such as the kidney invigorating, clearing heat and moistening lung, promoting the production of body fluid to quench thirst, clearing stomach yin nourishing, thereby not only can be applicable to the disease of the diabetes due to kidney-deficiency in the diabetes, and applicable to the usefulness of various diabetic therapy.General patient took about a week, and maximum courses of treatment, (30 days) blood glucose, glucose in urine can be reduced to normal value, but just rehabilitation in 3~6 months, and have no side effect.The present invention adopts sticky rice syrup pill or capsule powder charge, both has been convenient to preserve, and is convenient to the patient again and quantitatively takes, and has also overcome because of the patient avoids sugar simultaneously and should not take the inconvenience that honeyed pill brings.Therefore, the present invention has and strengthens human body cell vigor and immunologic function, improves the secretion of insulin complex functionality, and blood sugar lowering, blood fat reducing are rapid, and is high and have no side effect and be convenient to preserve and characteristics such as quantitatively take in order to the curative effect of treatment diabetes.The present invention adopts each crude drug mixing to pulverize, and has also overcome the independent defectives such as pulverizing and increase back operation patent medicine production difficulty that are difficult for such as Fructus Lycii.
Embodiment
Present embodiment is an example to produce pill:
At first will be up to the standards and through each crude drug of sterilization treatment by Fructus Lycii, the Radix Astragali, each 1200g of Rhizoma dioscoreae, Radix Ginseng, each 520g of Radix Trichosanthis, Radix Puerariae 800g, the Radix Rehmanniae, Fructus Crataegi, each 420g of Rhizoma Polygonati, Radix Notoginseng, each 200g mixing of Radix Scrophulariae are sent into pulverizer and are pulverized to stand-by behind the smalls, because pulverizer itself has sieve plate, so reuse has not sieved;
Add water 3kg by the first-class Oryza glutinosa of 100g and be boiled into the Oryza glutinosa juice, after filtration, the cooling after approximately the 2.5kg juice; Add 250g glycerol to this juice again, mix homogeneously, the serosity that is made as binding agent is stand-by;
Pill: above-mentioned powder is packed in the blender, and slowly, will drench as the serosity of binding agent evenly into blender, it is stirred patent medicine mud, drench amount with messenger drug mud smoothly slivering degree of being (pouring also need before going into serosity again row stir evenly), medicine mud after will stirring is again sent blender, the pill of φ 6mm is made in rubbing, after oven drying is handled, can obtain 7 over thousands of gram pills altogether.
This pill is used for the treatment of, each 5~10g, day clothes 3 times; After treatment, each 4~8g, day clothes 3 times serve on 3~6 courses of treatment.

Claims (3)

1, a kind of diabetes Chinese patent medicine of controlling is characterized in that pill or capsule that this patent medicine is made up of Fructus Lycii, Radix Ginseng, the Radix Astragali, Rhizoma Dioscoreae, Radix Puerariae, Radix Trichosanthis, the Radix Rehmanniae, Radix Notoginseng, Fructus Crataegi, Radix Scrophulariae and Rhizoma Polygonati, also or powder; Weight ratio in the patent medicine between each composition: be respectively radix 1 with Fructus Lycii, the Radix Astragali, Rhizoma Dioscoreae, then Radix Ginseng, Radix Trichosanthis are respectively 0.40~0.46, Radix Puerariae is 0.65~0.70, and the Radix Rehmanniae, Fructus Crataegi, Rhizoma Polygonati are respectively 0.33~0.39, and Radix Notoginseng, Radix Scrophulariae are respectively 0.16~0.23.
2,, it is characterized in that the Radix Ginseng in the patent medicine can adopt Radix Panacis Quinquefolii to replace, and usage ratio is constant by the described diabetes Chinese patent medicine of controlling of claim 1.
3, the pill production method of controlling diabetes usefulness Chinese patent medicine of claim 1 is characterized in that:
A. at first all mix in proportion or mix respectively to pulverize with acceptance(check) and through each crude drug of sterilization treatment and be smalls, it is stand-by to sieve;
B. slurrying liquid: in the ratio of Oryza glutinosa and water 1: 20~30, earlier it is boiled into the Oryza glutinosa juice, after filtration, after the cooling,, make serosity, stand-by by the ratio adding glycerol and the mix homogeneously of Oryza glutinosa juice weight 8~15%;
C. after the powder that whole powder that mix pulverizing among the A maybe will be mixed pulverizing respectively weighs up mixing by formula proportion again, add serosity, the rubbing pill as binding agent;
D. at last made pill is carried out dried.
CN96117548A 1996-05-09 1996-05-09 Method for producing Chinese patent medicine for curing diabetes and its pill Expired - Fee Related CN1062154C (en)

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CN1062154C true CN1062154C (en) 2001-02-21

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100415270C (en) * 2000-10-20 2008-09-03 孙喆 Diabetes treating medicine
CN100428948C (en) * 2004-05-22 2008-10-29 刘贤英 Chinese health-care medicine for reducing blood sugar and preventing from diabete complication and its preparation
CN100444864C (en) * 2004-11-04 2008-12-24 苗毅韧 Chinese medicinal formulation for rehabilitating pancreatic islet function and decreasing blood sugar and preparation process thereof
CN110624068A (en) * 2019-10-31 2019-12-31 邹荣成 Fermented glutinous rice unitary liquid and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103305A (en) * 1993-11-27 1995-06-07 李南山 Diabetes powder and its preparing method
CN1106271A (en) * 1994-02-01 1995-08-09 张树成 Method for prepn. of medicinal introducing bag for treating diabetes mellitus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1103305A (en) * 1993-11-27 1995-06-07 李南山 Diabetes powder and its preparing method
CN1106271A (en) * 1994-02-01 1995-08-09 张树成 Method for prepn. of medicinal introducing bag for treating diabetes mellitus

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《中医研究》9(3) 1996.3.1 闫喜英等,降糖三消冲剂配合中药敷脐治疗II型糖尿病108例临床观察 *
《湖南中医杂志》5(3) 1989.1.1 申健,三消汤治疗糖尿病 *
《湖南中医杂志》5(3) 1989.1.1 申健,三消汤治疗糖尿病;《中医研究》9(3) 1996.3.1 闫喜英等,降糖三消冲剂配合中药敷脐治疗II型糖尿病108例临床观察 *

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