CN1103305A - Diabetes powder and its preparing method - Google Patents

Diabetes powder and its preparing method Download PDF

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Publication number
CN1103305A
CN1103305A CN 93115038 CN93115038A CN1103305A CN 1103305 A CN1103305 A CN 1103305A CN 93115038 CN93115038 CN 93115038 CN 93115038 A CN93115038 A CN 93115038A CN 1103305 A CN1103305 A CN 1103305A
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radix
diabetes
powder
rhizoma
medicine
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李南山
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Abstract

The powdered medicine for diabetes mellitus is prepared with 17 Chinese-medicinal herbs such as ginseng, ophiopogon root, schisandra fruit, astragalus root, pollen, etc. through mixing, baking at 60 deg.C for 3 hr, cooling and crashing. It is suitable for weak diabetic with total effective rate of 94.5%.

Description

Diabetes powder and its preparing method
The present invention is the Chinese patent medicine and the compound method thereof of a kind of various diabetess of treatment (diabetes).
Diabetes is that polyphagia is become thin with thirsty polydipsia, and the frequent micturition amount is many, and fatigue and weak is a principal character, and doctor trained in Western medicine is called diabetes.At present, China patient that quenches one's thirst accounts for 0.67% of total population, and the city prevalence is higher than the rural area, and fewer, with regard to the world, the incidence and mortality of diabetes and complication thereof has become the third-largest disease of harm humans health and lives.
Doctor trained in Western medicine just relies on medicine control, can't effect a radical cure, and side effect is many.The Western medicine of treatment diabetes can be divided three classes both at home and abroad at present: the one, and insulin, mainly be applicable to child, teenager insulin dependent diabetes mellitus (IDDM) people, and be lifelong dependence, and easily forming hypoglycemia, rebound hyperglycemia, part patient also can cause side effect such as lipodystrophy; The 2nd, oral sulfonylurea drugs comprises tolbutamide, glyburide, and diamicron, gram sugar is sharp, Gliguidone, diabetes pill (Chinese and Western combination), sulfonylurea drugs easily produces hypoglycemia, sometimes hepatocholangeitis can take place, slight jaundice, liver function is damaged; The 3rd, biguanides comprises insoral, metformin, and these medicines all can only be controlled diabetes, and biguanides easily produces side effect such as hyperlactacidemia, lactic acidosis.The inside and outside medical circle in native land more and more turns to Chinese medicine to attention.
What the TCM treatment of diabetes curative effect was high is decoction, and the cure rate statistics is 20-30%, but decoction is determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, and motility is big, does not have fixed Cheng Fang, patent medicine, takes medicine and inconvenience.
The Chinese patent drugs for treatment diabetes have YUQUAN WAN, JIANGTANGSHU, blood-sugar reducing tablets etc., and the advantage of these medicines is non-evident effects, and effective percentage is 50-85%, but also are by medicine control, do not see the report of radical cure so far, and only are applicable to the stable type patient.For example the YUQUAN WAN prescription is that eight flavor medicines such as Radix Ginseng, Fructus Schisandrae Chinensis, Radix Ophiopogonis, the Radix Astragali, Pachyrhizua angulatus, pollen, the Radix Rehmanniae, Fructus Mume (second filial generation YUQUAN WAN prescription) are formed, it only is applicable to " deficiency of both QI and YIN " type diabetes patient, for " deficiency of YIN is scorching " type, " blood-stasis internal-depression ", " deficiency of both YIN and YANG " type is just inapplicable.
The object of the present invention is to provide the Chinese patent medicine-diabetes powder and the compound method thereof of a kind of treatment diabetes (diabetes), it has not only taking convenience but also curable advantage, but also adapts to the diabetes patient of multiple weak type.
The prescription of diabetes powder of the present invention consists of: Radix Ginseng, and Radix Ophiopogonis, the five tastes, the Radix Astragali, Pachyrhizua angulatus, pollen, Endothelium corneum, Rhizomadioscoreae, Poria, the Radix Rehmanniae, Cortex Moutan, Fructus Corni, Radix Salviae Miltiorrhizae, Radix Notoginseng, Rhizoma Coptidis, Radix Panacis Quinquefolii, Rhizoma Alismatis amounts to 17 kinds.
The compound method of diabetes powder:
1 selects the some jin of the rotten tablet of flavour of a drug giving off a strong fragrance, gloss, free from insect pests and mould circle;
2 mix above-mentioned all medicines by a certain percentage and to mix thoroughly;
3 send the tablet of mixing thoroughly into 60 spends in the drying rooms, takes out cooling after 3 hours;
The pulverizing of 4 usefulness pulverizers.
The 5 powder 5-10g that crush are respectively charged into sealing in the edible book film bag, and the sack of again 90 pouches being packed into is a course of treatment packing.
The part by weight of each medicine prescription of diabetes powder of the present invention can be Radix Ginseng: Radix Ophiopogonis: the five tastes: the Radix Astragali: Pachyrhizua angulatus: pollen: Endothelium corneum: Rhizomadioscoreae: Poria: the Radix Rehmanniae: Cortex Moutan: Fructus Corni: Radix Salviae Miltiorrhizae: Radix Notoginseng: Rhizoma Coptidis: Radix Panacis Quinquefolii: Rhizoma Alismatis=2: 3: 1.6: 6: 3: 4: 2: 6: 2: 4: 2: 2: 4: 1.6: 1.6: 2: 1.2.
A prescription embodiment: Radix Ginseng 10g, Radix Ophiopogonis 15g, five tastes 8g, Radix Astragali 30g, Pachyrhizua angulatus 15g, pollen 20g, Endothelium corneum 10g, Rhizomadioscoreae 30g, Poria 10g, Radix Rehmanniae 20g, Cortex Moutan 10g, Fructus Corni 10g, Radix Salviae Miltiorrhizae 20g, Radix Notoginseng 8g, Rhizoma Coptidis 8g, Radix Panacis Quinquefolii 10g, Rhizoma Alismatis 6g.
Pharmacology analysis:
Radix Ginseng: big tonifying the lung gas, supplementing QI for promoting the production of body fluid and quenching the thirst can blood sugar lowering;
Radix Ophiopogonis: clearing stomach is quenched the thirst, YIN nourishing and the production of body fluid promoting;
The five tastes: the nourishing kidney of astringing the lung, the arresting sweating that promotes the production of body fluid can promote liver glycogen heteroplasia and glycogen to decompose; Radix Ophiopogonis, the auxilliary Radix Ginseng two of the five tastes are rescued gas the moon.
The Radix Astragali: invigorating the spleen and replenishing QI, the hyperglycemia that epinephrine is caused has inhibitory action;
Rhizomadioscoreae: spleen reinforcing controlling nocturnal emission with astringent drugs; The Radix Astragali, Rhizomadioscoreae have obvious urine glucose lowering effect with improving polyphagia polyphagia symptom;
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating and in, blood sugar lowering;
Cortex Moutan: clearing away heat and cooling blood blood circulation promoting and blood stasis dispelling;
The Radix Rehmanniae: clearing away heat and promoting production of body fluid;
Fructus Corni: invigorating the liver and kidney, the controlling nocturnal emission with astringent drugs arresting sweating is restrained empty water and is ended diabetes due to kidney-deficiency, and the assistant Radix Rehmanniae, Cortex Moutan rush down asthenic fire clearly;
Pachyrhizua angulatus: kind control gastric heat thirsty and can elevate a turnable ladder sun clearly;
Pollen: moisturize and promote the production of body fluid and quench the thirst, " medical science main story " claims that pollen is to control the panacea of quenching one's thirst;
Endothelium corneum: tonifying the spleen and stomach, it is long-pending to help digestion, the arresting enursis seminal emission, it is precise and tiny that dissipating fluid-retention is eaten, and the acid of the assistant five tastes is received to reinforce the kidney;
Rhizoma Coptidis: pathogenic fire reducing is scorching to go;
Radix Panacis Quinquefolii: the key medicine of nourishing the stomach to promote the production of body fluid, help all medicine giving young employees remedial-courses in general knowledge and vocational skills gas the moon, strengthen all drug effect power;
Radix Notoginseng: blood circulation promoting and blood stasis dispelling, Cortex Moutan nourshing blood and promoting blood circulation and energy blood stasis dispelling, the same usefulness of two medicines plays blood stasis dispelling
And just do not hinder, with the same usefulness of Qi-tonifying drug, play QI and blood regulating, by reducing diabetes patient's blood viscosity, assist all medicines with blood sugar lowering;
Rhizoma Alismatis: diuretic makes all medicine tonifys without causing stagnation with regulating fluid apssage.
Last 17 flavor medicines are made up of four groups of medicines: the one, and SHENGMAI SAN, SHENGMAI SAN tonifying the lung gas, supplementing QI for promoting the production of body fluid, for controlling deficiency of both QI and YIN, wanting of thirsty polydipsia is square; The 2nd, good wine soup goes the Rhizoma Anemarrhenae to add Radix Panacis Quinquefolii, Rhizoma Coptidis, and in order to the spleen invigorating QI invigorating, elevate a turnable ladder vigour is grown Kidney-Yinly greatly, add Rhizoma Coptidis and fall the heat of heart-fire with the lung heat clearing stomach, then the disease of rapid digestion of food and polyorexia from disappearing thirsty ending; The 3rd, LIUWEI DIHUANG WAN is the name side of the nourishing kidney yin, and the kidney being the origin of congenital constitution, deficiency of kidney-YIN, hyperactivity of deficient fire then, the five internal organs are impaired, so, take the photograph kidney water and make flat then the quenching one's thirst of asthenic fire end " Thorough Knowledge of Medicine " meaning to join sun with the LIUWEI DIHUANG WAN YIN nourishing: " control the method that disappears; do not have the upper, middle and lower of branch; control kidney earlier for anxious, dimension Six-element eight flavor balls are obeyed with card, fall its heart-fire; grow its kidney water, and are then thirsty from ending." especially the three parts share to such an extent that complement each other, bring out the best in each other; The 4th, Radix Salviae Miltiorrhizae and Radix Notoginseng, in order to the nourshing blood and promoting blood circulation blood stasis dispelling, QI and blood regulating, so traditional Chinese medical science older generation professor Liu Shunong thinks before death: " deficiency of YIN is scorching to be the main cause of diabetes blood stasis." it is reported that diabetics blood viscosity and plasma viscosity raise, the erythrocyte aggregation ability strengthens, and deformability reduces.From diabetes patient's common " arthralgia due to stagnation of blood ", apoplectic hemiplegia clinically, all relevant with blood stasis, thus when controlling diabetes, add drug for invigorating blood circulation and eliminating stasis and more can improve curative effect with the replenishing YIN and removing heat medicine, and can complication prevention.
Zoopery.
Diabetes powder of the present invention proves that by the test of alloxan induced mice hyperglycemia pathology model blood sugar lowering this product has remarkable blood sugar reducing function, administration five days, and experimental mice blood glucose matter reduces 90ng% than the matched group blood glucose value, continues medication for two weeks, acts on more obvious.Once oral 2g/kg this product, the hyperglycemia rabbit that the oxidation cortisone is caused has tangible blood sugar reducing function, does not have influence for normal rabbits.Normal my son is pressed per kilogram 1g administration, and experimental group increases by 0.3 kilogram than the matched group weight average after 30 days, proves that this product has the effect that promotes its growth promoter to brood.Proportionately human oral dosage is mixed the my son that food is raised 5 kilograms of body weight for 10 times, observes from the live body to anatomical physiology after 15 days and does not all find toxic and side effects.
Zoopery proof this product has tangible blood sugar reducing function, promotes brood to send out children's effect, has no side effect.
Indication: this product mainly is applicable to non-insulin-dependent diabetes mellitus, and insulin dependent diabetes mellitus (IDDM) is had certain curative effect.
Clinical practice:
The diabetes powder Chinese patent medicine, through the non-insulin-depending type patients clinical being tried out and being visited 459 people, produce effects 186 examples account for total number of persons 40.5% as a result, effective 248 examples account for 54%, and total effective rate is 94.5%, invalid 25 examples account for total number of persons 5.5%, wherein 142 examples not recurrence more than 2 years after this product is treated; Visit teenager insulin-dependent patient 12 examples, the first quarter moon of taking medicine begins effective 7 examples, and produce effects 2 routine total effective rates are 75%.Substantial connection is arranged the therapeutic effect of this product and the state of an illness, the course of disease, the course of treatment.
Side effect: do not see the toxic and side effects reaction during this product is clinical.
Distinct advantages of the present invention:
One medication prescription is more comprehensive, is based on three types of diabetes in like manner, and three dirty closing are controlled, and outstanding nourishing kidney yin is paid attention to the spleen invigorating QI invigorating, and the nourishing the stomach heat clearing away is aided with the lung-yin nourishing of tonifying the lung gas, and assistant makes human body yin-yang balancing with the medicine of nourshing blood and promoting blood circulation blood stasis dispelling, and QI and blood is in harmonious proportion, three types of diabetes spontaneous recovery.
Two this product both were applicable to " deficiency of both QI and YIN " type and " deficiency of YIN is scorching " type, also be applicable to " blood-stasis internal-depression " type, originally add Radix Aconiti Lateralis Preparata (part by weight 1-2), Cortex Cinnamomi (part by weight 1-2), celestial being's spleen (part by weight 2-3) Yang-strengthening drug, also applicable to " deficiency in both YIN and YANG " type.
Three this product are not only applicable to the stable diabetes mellitus people, to teenager insulin dependent diabetes mellitus (IDDM) people, certain curative effect are arranged also.Modern medicine study is thought, the most genus heredity of juvenile diabetes, and the traditional Chinese medical science is called the natural endowment deficiency.The present invention had both paid attention to training and had mended the congenital foundation kidney, did not ignore nourishing the foundation of acquired constitution spleen (stomach) again.
Four this product have the clinical activity of Chinese medicine decoction, add and subtract with card according to determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.For example, dry mouth and throat, thready and rapid pulse person, we add Rhizoma Polygonati Odorati, Herba Dendrobii, Radix Scrophulariae, and each part by weight is 2-3; The excessive thirst polydipsia, polyphagia, the full and rapid pulse person originally can add stone lamb (part by weight 3-6), the Rhizoma Anemarrhenae (part by weight 2-3).
Usage and dosage: oral each 5-10g, the child is cut down according to the circumstance, and every day three times, obey half an hour ante cibum.
Storage: protection against the tide.

Claims (11)

1, the Chinese patent medicine-diabetes powder of a kind of treatment diabetes (diabetes) is characterized in that it by Radix Ginseng, Radix Ophiopogonis, and the five tastes, the Radix Astragali, Pachyrhizua angulatus, pollen, Endothelium corneum, Rhizomadioscoreae, Poria, the Radix Rehmanniae, Cortex Moutan, Fructus Corni, Radix Salviae Miltiorrhizae, Radix Notoginseng, Rhizoma Coptidis, Radix Panacis Quinquefolii, Rhizoma Alismatis amounts to ten seven flavor medicines and forms.
2, diabetes powder as claimed in claim 1 is characterized in that the part by weight of each medicine prescription is: Radix Ginseng: Radix Ophiopogonis: the five tastes: the Radix Astragali: Pachyrhizua angulatus: pollen: Endothelium corneum: Rhizomadioscoreae: Poria: the Radix Rehmanniae: Cortex Moutan: Fructus Corni: Radix Salviae Miltiorrhizae: Radix Notoginseng: Rhizoma Coptidis: Radix Panacis Quinquefolii: Rhizoma Alismatis=2: 3: 1.6: 6: 3: 4: 2: 6: 2: 4: 2: 2: 4: 1.6: 1.6: 2: 1.2.
3, as claim 1,2 described diabetes powders, it is characterized in that, add Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, celestial being's spleen " deficiency in both YIN and YANG " type patient.
4, as claim 1,2 described diabetes powders, it is characterized in that the thready and rapid pulse person is added Rhizoma Polygonati Odorati, Herba Dendrobii, Radix Scrophulariae, the full and rapid pulse person is added stone lamb, the Rhizoma Anemarrhenae.
5, diabetes powder as claimed in claim 3 is characterized in that Radix Aconiti Lateralis Preparata component 1-2, Cortex Cinnamomi component 1-2, celestial being's spleen component 2-3.
6, diabetes powder as claimed in claim 4 is characterized in that the component of Rhizoma Polygonati Odorati, Herba Dendrobii, Radix Scrophulariae is 2-3.
7, the compound method of diabetes powder according to claim 1 is characterized in that:
1) selects the some jin of the rotten tablet of flavour of a drug giving off a strong fragrance, gloss, free from insect pests and mould circle;
2) above-mentioned all medicines are mixed by a certain percentage mix thoroughly;
3) tablet of mixing thoroughly is sent in the 60 degree drying rooms, taken out cooling after 3 hours;
4) pulverize with pulverizer.
8, as the compound method of diabetes powder as described in the claim 7, the blended part by weight of medicine that it is characterized in that respectively distinguishing the flavor of is: Radix Ginseng: Radix Ophiopogonis: the five tastes: the Radix Astragali: Pachyrhizua angulatus: pollen: Endothelium corneum: Rhizomadioscoreae: Poria: the Radix Rehmanniae: Cortex Moutan: Fructus Corni: Radix Salviae Miltiorrhizae: Radix Notoginseng: Rhizoma Coptidis: Radix Panacis Quinquefolii: Rhizoma Alismatis=2: 3: 1.6: 6: 3: 4: 2: 6: 2: 4: 2: 2: 4: 1.6: 1.6: 2: 1.2.
9, as the compound method of diabetes powder as described in the claim 7, the blended part by weight of medicine that it is characterized in that respectively distinguishing the flavor of is: Radix Ginseng: Radix Ophiopogonis: the five tastes: the Radix Astragali: Pachyrhizua angulatus: pollen: Endothelium corneum: Rhizomadioscoreae: Poria: the Radix Rehmanniae: Cortex Moutan: Fructus Corni: Radix Salviae Miltiorrhizae: Radix Notoginseng: Rhizoma Coptidis: Radix Panacis Quinquefolii: Rhizoma Alismatis: Radix Aconiti Lateralis Preparata: Cortex Cinnamomi: celestial being's spleen=2: 3: 1.6: 6: 3: 4: 2: 6: 2: 4: 2: 2: 4: 1.6: 1.6: 2: 1.2: 1-2: 1-2: 1-2: 2-3.
10, as the compound method of diabetes powder as described in the claim 8,9, it is characterized in that the part by weight of Rhizoma Polygonati Odorati, Herba Dendrobii, Radix Scrophulariae is 1-2.
11, as the compound method of diabetes powder as described in the claim 8,9, the part by weight that it is characterized in that stone lamb, the Rhizoma Anemarrhenae is stone lamb 3-6, Rhizoma Anemarrhenae 2-3.
CN 93115038 1993-11-27 1993-11-27 Diabetes powder and its preparing method Pending CN1103305A (en)

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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062154C (en) * 1996-05-09 2001-02-21 潘端 Method for producing Chinese patent medicine for curing diabetes and its pill
CN1098049C (en) * 2000-04-29 2003-01-08 广州立帜实业有限公司 Method for storage of pueraria root specially adapted for producing starch
CN100350940C (en) * 2005-10-19 2007-11-28 暨南大学 Medicine for treating diabetes and its complications and its preparing process
CN100434099C (en) * 2005-01-31 2008-11-19 张培轩 Medicinal composition for diabete and its making method
CN102755530A (en) * 2012-07-15 2012-10-31 王俊茹 Traditional Chinese medicine composition for treating diabetic foot and application thereof
CN102861201A (en) * 2011-07-05 2013-01-09 北京中医药大学 Medicine composition for treating diabetes and preparation method thereof
CN101708302B (en) * 2009-12-08 2013-01-09 张为举 Chinese medicinal preparation for treating diabetes and preparation method thereof
CN103505630A (en) * 2013-09-30 2014-01-15 周复礼 Medicine for treating diabetes and preparation method thereof
CN103751519A (en) * 2014-01-21 2014-04-30 四川绿禾药业有限公司 Traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN104367912A (en) * 2014-10-27 2015-02-25 宋秀香 Traditional Chinese medicine for preventing and treating diabetes mellitus and preparation method of traditional Chinese medicine tablet
CN105194342A (en) * 2015-10-26 2015-12-30 冯天宁 Traditional Chinese medicinal composition for treating diabetes
CN108114228A (en) * 2017-08-15 2018-06-05 黄冈市中医医院 A kind of Chinese medicine composition for treating diabete and preparation method thereof
CN108324852A (en) * 2018-04-19 2018-07-27 合肥市风达农业有限责任公司 A kind of Chinese medicine composition for treating diabetes
CN111195326A (en) * 2018-11-19 2020-05-26 安顺玉龙医院 Preparation method of blood sugar-reducing and thirst-quenching powder
CN113082182A (en) * 2021-04-12 2021-07-09 刘淑娥 Traditional Chinese medicine for treating diabetes

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062154C (en) * 1996-05-09 2001-02-21 潘端 Method for producing Chinese patent medicine for curing diabetes and its pill
CN1098049C (en) * 2000-04-29 2003-01-08 广州立帜实业有限公司 Method for storage of pueraria root specially adapted for producing starch
CN100434099C (en) * 2005-01-31 2008-11-19 张培轩 Medicinal composition for diabete and its making method
CN100350940C (en) * 2005-10-19 2007-11-28 暨南大学 Medicine for treating diabetes and its complications and its preparing process
CN101708302B (en) * 2009-12-08 2013-01-09 张为举 Chinese medicinal preparation for treating diabetes and preparation method thereof
CN102861201B (en) * 2011-07-05 2015-04-15 北京中医药大学 Medicine composition for treating diabetes and preparation method thereof
CN102861201A (en) * 2011-07-05 2013-01-09 北京中医药大学 Medicine composition for treating diabetes and preparation method thereof
CN102755530A (en) * 2012-07-15 2012-10-31 王俊茹 Traditional Chinese medicine composition for treating diabetic foot and application thereof
CN103505630A (en) * 2013-09-30 2014-01-15 周复礼 Medicine for treating diabetes and preparation method thereof
CN103505630B (en) * 2013-09-30 2015-10-21 周复礼 A kind of medicine for the treatment of diabetes and preparation method thereof
CN103751519A (en) * 2014-01-21 2014-04-30 四川绿禾药业有限公司 Traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN104367912A (en) * 2014-10-27 2015-02-25 宋秀香 Traditional Chinese medicine for preventing and treating diabetes mellitus and preparation method of traditional Chinese medicine tablet
CN105194342A (en) * 2015-10-26 2015-12-30 冯天宁 Traditional Chinese medicinal composition for treating diabetes
CN105194342B (en) * 2015-10-26 2018-10-23 冯天宁 It is a kind of to treat Chinese medicine for treating diabetes composition
CN108114228A (en) * 2017-08-15 2018-06-05 黄冈市中医医院 A kind of Chinese medicine composition for treating diabete and preparation method thereof
CN108324852A (en) * 2018-04-19 2018-07-27 合肥市风达农业有限责任公司 A kind of Chinese medicine composition for treating diabetes
CN111195326A (en) * 2018-11-19 2020-05-26 安顺玉龙医院 Preparation method of blood sugar-reducing and thirst-quenching powder
CN113082182A (en) * 2021-04-12 2021-07-09 刘淑娥 Traditional Chinese medicine for treating diabetes

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