CN100434099C - Medicinal composition for diabete and its making method - Google Patents
Medicinal composition for diabete and its making method Download PDFInfo
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- CN100434099C CN100434099C CNB2005100049729A CN200510004972A CN100434099C CN 100434099 C CN100434099 C CN 100434099C CN B2005100049729 A CNB2005100049729 A CN B2005100049729A CN 200510004972 A CN200510004972 A CN 200510004972A CN 100434099 C CN100434099 C CN 100434099C
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- momordicae charantiae
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Abstract
The present invention relates to a traditional Chinese medicine composition for eliminating a thirst-dispersing symptom and a preparation method thereof. For solving the problems of difficult swallow and long period of treatment for patients, the present invention provides a medicine composition for eliminating a thirst-dispersing symptom, the medicine composition formed by preparing fresh balsam pear with 15 traditional Chinese medicine herbs, such as clematis root, platycodon root, water plantain, pig's pancreas powder, rhizoma, milkvetch root, self-heal, red sage root, notoginseng, ground beeltle, cornel, ginseng, stiff silkorm, winged euonymus twig and lychee seed, has the advantages of benefiting Qi, promoting the production of fluid, promoting blood circulation to remove meridian obstruction and providing convenience for taking, wherein the gross weight of the 15 traditional Chinese medicine herbs and the gross weight of the fresh balsam pear are prepared according to the proportion of 1 to 2.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly a kind of Chinese herbal medicine material that derives from also can be eliminated pharmaceutical composition of diabetes and preparation method thereof.
Background technology
As everyone knows, diabetes is a kind of common frdquently encountered disease of endocrine and metabolic disorders, can occur in all age group, being characterized as of its performance: polydipsia, polyuria, polyphagia and emaciated physique etc., if disease controlling not, the acid poisoning severe chronic pathological changes, the ketoboidies disease of multiple organ can appear.At present, insulinogenic therapeutic method or drug treatment are generally adopted in the treatment of diabetes.Adopt the insulin method, then can produce antibody, reduce health autoimmunity, impel microvascular pathological changes, cause suffering from insulin disease; And the drug treatment of employing Chinese herbal medicine, curative effect is not fairly obvious.On the Chinese patent communique, announced " help producing saliva and slaking thirst traditional Chinse " of a kind of ZL00110486 on October 13rd, 2004, it is powder or the piece agent that is made of the Rhizoma Atractylodis Macrocephalae, Radix Trichosanthis, Rhizoma Anemarrhenae, FRUCTUS LYCII, Radix Rehmanniae, RHIIZOMA DIOSCOREAE frOm Henan of China, Herba Euphorbiae Helioscopiae, RADIX PUERARIAE, Poria, Radix Ginseng, Rhizoma Polygonati, Fructus Corni, Carapax et Plastrum Testudinis, this medicine is a pure natural medical, but swallow the comparison difficulty when patient takes, the course of treatment is long.
Summary of the invention
In order to address the above problem, the purpose of this invention is to provide a kind of can supplementing QI for promoting the production of body fluid, promoting blood circulation to remove obstruction in the collateral, a kind of pharmaceutical composition for the treatment of diabetes of taking convenience, short treating period again.
The object of the present invention is achieved like this: a kind of pharmaceutical composition for the treatment of diabetes, by Radix Clematidis, Radix Platycodonis, Rhizoma Alismatis, Pancreas Sus domestica powder, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Spica Prunellae, Radix Salviae Miltiorrhizae, Radix Notoginseng, Eupolyphaga Seu Steleophaga, Fructus Corni, Radix Ginseng, Bombyx Batryticatus, Ramulus Euonymi, 15 kinds of Chinese crude drugs and bright Fructus Momordicae charantiae that Semen Litchi constitutes are formulated, wherein the weight portion of the weight of 15 kinds of Chinese crude drug total amounts and bright Fructus Momordicae charantiae is prepared according to 1: 2 ratio, and calculate by 100% by the gross weight that 15 kinds of Chinese crude drugs are formed, the percentage by weight of each component is: Radix Clematidis 1.5%-2.5%, Radix Platycodonis 1.5%-2.5%, Rhizoma Alismatis 1.5%-2.5%, Pancreas Sus domestica powder 1.5%-2.5%, Rhizoma Atractylodis Macrocephalae 2.5%-3.5%, Radix Astragali 2.5%-3.5%, Spica Prunellae 3.5%-4.5%, Radix Salviae Miltiorrhizae 3.5%-4.5%, Radix Notoginseng 3.5%-4.5%, Eupolyphaga Seu Steleophaga 3.5%-4.5%, Fructus Corni 5.5%-6.5%, Radix Ginseng 8%-15%, Bombyx Batryticatus 10%-15%, Ramulus Euonymi 15%-25%, Semen Litchi 20%-30%, and the percentage by weight of bright Fructus Momordicae charantiae is 2 times of above-mentioned 15 kinds of Chinese crude drug gross weights.
The optimization formula of preparation medicine of the present invention is:
Radix Clematidis 1.8%-2.2%, Radix Platycodonis 1.8%-2.2%, Rhizoma Alismatis 1.8%-2.2%, Pancreas Sus domestica powder 1.8%-2.2%, Rhizoma Atractylodis Macrocephalae 2.8%-3.2%, Radix Astragali 2.8%-3.2%, Spica Prunellae 3.8%-4.2%, Radix Salviae Miltiorrhizae 3.8%-4.2%, Radix Notoginseng 3.8%-4.2%, Eupolyphaga Seu Steleophaga 3.8%-4.2%, Fructus Corni 5.8%-6.2%, Radix Ginseng 9%-12%, Bombyx Batryticatus 9%-12%, Ramulus Euonymi 18%-22%, Semen Litchi 22%-26%, and the percentage by weight of bright Fructus Momordicae charantiae is 2 times of above-mentioned 15 kinds of Chinese crude drug gross weights.
Preparation process of the present invention is that the several steps according to following order carries out:
1. earlier will above-mentioned 15 kinds of medicines except that bright Fructus Momordicae charantiae weigh by weight clean after, be put into and carry out the coarse grain pulverizing in the container, mistake 20 mesh sieves.
2. more load weighted bright Fructus Momordicae charantiae is cleaned, pushed and squeeze the juice.
3. will cross 15 kinds of mixing coarse powder of 20 mesh sieves and pour in the juice of bright Fructus Momordicae charantiae, fully stir oven dry.
4. after drying 12 hours, be ground into fine powder, cross 80 mesh sieves, mixing.
5. filled capsules is made 1000 particulate Chinese medicinal capsules.
Compared with prior art, the present invention not only has supplementing QI for promoting the production of body fluid, promoting blood circulation to remove obstruction in the collateral, nourishing YIN to lower pathogenic fire, blood sugar lowering and protects the liver, calms the nerves and quench the thirst, and taking convenience, short treating period, be easy to absorb, stability of drug is strong.
Good effect of the present invention is: do not contain the hypoglycemic medicine composition of Western medicine, and formulated by pure natural medical, after the patient takes medicine, just can break away from course of treatment dependence to insulin, effect is remarkable after 2~3 courses of treatment, but drug withdrawal after 5 courses of treatment, does not recur, and need not take medicine all the life.
The invention will be further described below in conjunction with embodiment.
Embodiment 1
Take by weighing medicine according to following proportioning:
Radix Clematidis 10g, Radix Platycodonis 10g, Rhizoma Alismatis 10g, Pancreas Sus domestica powder 10g, Rhizoma Atractylodis Macrocephalae 15g, Radix Astragali 15g, Spica Prunellae 20g, Radix Salviae Miltiorrhizae 20g, Radix Notoginseng 20g, Eupolyphaga Seu Steleophaga 20g, Fructus Corni 30g, Radix Ginseng 50g, Bombyx Batryticatus 50g, Ramulus Euonymi 100g, Semen Litchi 120g, bright Fructus Momordicae charantiae 1000g.
At first above-mentioned 15 kinds of medicines except that bright Fructus Momordicae charantiae are weighed by weight clean after, be put into and carry out coarse grain in the container and pulverize, cross 20 mesh sieves; And after bright Fructus Momordicae charantiae cleans by weight, squeeze the juice.Pour 15 kinds of mixing coarse powder crossing 20 mesh sieves in the bright Fructus Momordicae charantiae squeezeding juice fully stirring, dry.Dry after 12 hours, be ground into fine powder jointly, cross 80 mesh sieves, mixing, filled capsules is made 1000 particulate Chinese medicinal capsules.
Embodiment 2
Take by weighing medicine according to following proportioning:
Radix Clematidis 7.5g, Radix Platycodonis 7.5g, Rhizoma Alismatis 7.5g, Pancreas Sus domestica powder 7.5g, Rhizoma Atractylodis Macrocephalae 12.5g, Radix Astragali 12.5g, Spica Prunellae 17.5g, Radix Salviae Miltiorrhizae 17.5g, Radix Notoginseng 17.5g, Eupolyphaga Seu Steleophaga 17.5g, Fructus Corni 27.5g, Radix Ginseng 40g, Bombyx Batryticatus 40g, Ramulus Euonymi 75g, Semen Litchi 100g get bright Fructus Momordicae charantiae 815g.
At first earlier will above-mentioned 15 kinds of medicines except that bright Fructus Momordicae charantiae weigh by weight clean after, be put into and carry out the coarse grain pulverizing in the container, mistake 20 mesh sieves; And after bright Fructus Momordicae charantiae cleans by weight, squeeze the juice.Pour 15 kinds of mixing coarse powder crossing 20 mesh sieves in the bright Fructus Momordicae charantiae squeezeding juice fully stirring, dry.Dry after 12 hours, be ground into fine powder jointly, cross 80 sieves, mixing, filled capsules is made 800 particulate Chinese medicinal capsules.
Embodiment 3
Take by weighing medicine according to following proportioning:
Radix Clematidis 15g, Radix Platycodonis 15g, Rhizoma Alismatis 15g, Pancreas Sus domestica powder 15g, Rhizoma Atractylodis Macrocephalae 21g, Radix Astragali 21g, Spica Prunellae 27g, Radix Salviae Miltiorrhizae 27g, Radix Notoginseng 27g, Eupolyphaga Seu Steleophaga 27g, Fructus Corni 39g, Radix Ginseng 90g, Bombyx Batryticatus 90g, Ramulus Euonymi 150g, Semen Litchi 180g get bright Fructus Momordicae charantiae 1518g.
At first earlier will above-mentioned 15 kinds of medicines except that bright Fructus Momordicae charantiae weigh by weight clean after, be put in the container and carry out coarse powder, mistake 20 mesh sieves; And after bright Fructus Momordicae charantiae cleans by weight, squeeze the juice.15 kinds of crossing 20 mesh sieves are mixed coarse powder pour bright Fructus Momordicae charantiae into and fully stir in squeezing the juice, dry.Dry after 12 hours, be ground into fine powder jointly, cross 80 mesh sieves, mixing, filled capsules is made 1500 particulate Chinese medicinal capsules.
According to the capsule that the above embodiments are prepared, bottle every bottled 100; Oral, every day 3 times, each 2~10, eliminating cold for resuscitation water send down, and 2 months is a course of treatment.
The present invention determines diabetics through system's clinical observation of thousands of cases according to international diabetes diagnosis standard, and the obvious effective rate before and after taking is 100%, and cure rate is 96%, is applicable to diabetes, diabetes and complication.
Case 1
Zhou Shijing, the man 71 years old, lives Mengjin County, Henan family members institute of Nicotiana tabacum L. office.Suffer from diabetes in October, 2003, " three-hypers " tool height is not following, Light-headedness, numb limbs and tense tendons is also worn the pain symptom, and taking quenches one's thirst invigorates blood circulation behind the capsule, and blood glucose is stabilized in 5~6mmol/L always, the numb limbs and tense tendons shape and wear the pain symptom all feel disappearance, 5 kilograms of weight increase, spirit is as ordinary person.
Case 2
Nie Qiurong, the woman 65 years old, lives Mengjin County, Henan township enterprise administration.Find to suffer from diabetes from 1993, blood glucose is 16mmol/L, takes insoral often, can not have a rest in April, 2004, and body weight die-offs, and drops to 81 jin by original 110 jin, thirsty obviously, walking disorder, 1 li of walking is just had a rest.Beginning to take of the present invention quenching one's thirst from April, 2004 invigorates blood circulation behind the capsule, blood glucose is by 16mmol/L, reduce to 9.8mmol/L, 7.0mmol/L, 6.6mmol/L takes a turn for the better gradually, to in August, 2004 have a meal, have a rest, health has strength, weight increase more than 20 kilogram return to original more than 110 jin again.
Case 3
Xu Ling, the woman lives the Hebei Shijiazhuang City and builds Room 402,120 extra trade buildings, Beijing University street, and the patient goes to a doctor to the hospital of traditional Chinese hospital, Lankao city in March, 2003, this patient's blood glucose 24mmol/L at that time, glucose in urine four "+" number, insulin injection is existing more than a year.March 15 began to take capsule of the present invention, had stopped the injection of insulin after one month fully, and according to every day 3 times, each 2~6, stable disease is good at present, tested sugar and was "~" number, and spirit takes a turn for the better, and insomnia disappears, and defecation is normal.
Case 4
Lu Deming, the man, 67 years old is the cadre of Urumqi City general post office, " three-hypers " is outstanding before going to a doctor, the xerostomia polydipsia, polyuria reaches 12 times/day, and constipation earns a bare living by insulin injection always.In by the end of September, 2003 the hospital of traditional Chinese hospital, Lankao city go to a doctor, take capsule of the present invention certainly after, medication stopped the injection of insulin on the 15th, had alleviated the misery of everyday beating insulin, through the treatment of 2 courses of treatment, glucose in urine is negative, above-mentioned symptom disappears substantially.
Claims (3)
1, a kind of pharmaceutical composition for the treatment of diabetes, by Radix Clematidis, Radix Platycodonis, Rhizoma Alismatis, Pancreas Sus domestica powder, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Spica Prunellae, Radix Salviae Miltiorrhizae, Radix Notoginseng, Eupolyphaga Seu Steleophaga, Fructus Corni, Radix Ginseng, Bombyx Batryticatus, Ramulus Euonymi, 15 kinds of Chinese crude drugs of Semen Litchi and bright Fructus Momordicae charantiae are formed, it is characterized in that: in described 15 kinds of Chinese crude drug gross weights is 100%, the percentage by weight of 15 kinds of Chinese crude drugs is respectively: Radix Clematidis 1.5%-2.5%, Radix Platycodonis 1.5%-2.5%, Rhizoma Alismatis 1.5%-2.5%, Pancreas Sus domestica powder 1.5%-2.5%, Rhizoma Atractylodis Macrocephalae 2.5%-3.5%, Radix Astragali 2.5%-3.5%, Spica Prunellae 3.5%-4.5%, Radix Salviae Miltiorrhizae 3.5%-4.5%, Radix Notoginseng 3.5%-4.5%, Eupolyphaga Seu Steleophaga 3.5%-4.5%, Fructus Corni 5.5%-6.5%, Radix Ginseng 8%-15%, Bombyx Batryticatus 10%-15%, Ramulus Euonymi 15%-25%, Semen Litchi 20%-30%, the weight of bright Fructus Momordicae charantiae is 2 times of above-mentioned 15 kinds of Chinese crude drug gross weights.
2, a kind of pharmaceutical composition for the treatment of diabetes, by Radix Clematidis, Radix Platycodonis, Rhizoma Alismatis, Pancreas Sus domestica powder, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Spica Prunellae, Radix Salviae Miltiorrhizae, Radix Notoginseng, Eupolyphaga Seu Steleophaga, Fructus Corni, Radix Ginseng, Bombyx Batryticatus, Ramulus Euonymi, 15 kinds of Chinese crude drugs of Semen Litchi and bright Fructus Momordicae charantiae are formed, it is characterized in that: in described 15 kinds of Chinese crude drug gross weights is 100%, the percentage by weight of 15 kinds of Chinese crude drugs is respectively: Radix Clematidis 1.5%-2.5%, Radix Platycodonis 1.5%-2.5%, Rhizoma Alismatis 1.5%-2.5%, Pancreas Sus domestica powder 1.5%-2.5%, Rhizoma Atractylodis Macrocephalae 2.5%-3.5%, Radix Astragali 2.5%-3.5%, Spica Prunellae 3.5%-4.5%, Radix Salviae Miltiorrhizae 3.5%-4.5%, Radix Notoginseng 3.5%-4.5%, Eupolyphaga Seu Steleophaga 3.5%-4.5%, Fructus Corni 5.5%-6.5%, Radix Ginseng 8%-15%, Bombyx Batryticatus 9%-12%, Ramulus Euonymi 15%-25%, Semen Litchi 20%-30%, the weight of bright Fructus Momordicae charantiae is 2 times of above-mentioned 15 kinds of Chinese crude drug gross weights.
3, the method for preparing the described pharmaceutical composition of claim 1 is characterized in that this method is made up of following steps:
1. earlier will above-mentioned 15 kinds of Chinese crude drugs except that bright Fructus Momordicae charantiae weigh by weight clean after, be put into and carry out the coarse grain pulverizing in the container, mistake 20 mesh sieves,
2. more load weighted bright Fructus Momordicae charantiae is cleaned, is pushed and squeeze the juice,
3. 15 kinds of Chinese crude drug mixings coarse powder step being crossed 20 mesh sieves in are 1. poured in the juice of the bright Fructus Momordicae charantiae that 2. step make, and fully stir, dry,
4. after drying 12 hours, be ground into fine powder, cross 80 mesh sieves, mixing,
5. fill, make capsule.
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Citations (1)
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CN1103305A (en) * | 1993-11-27 | 1995-06-07 | 李南山 | Diabetes powder and its preparing method |
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CN1103305A (en) * | 1993-11-27 | 1995-06-07 | 李南山 | Diabetes powder and its preparing method |
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Granted publication date: 20081119 Termination date: 20170131 |