CN101352483B - Medicine for treating diabetes - Google Patents
Medicine for treating diabetes Download PDFInfo
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- CN101352483B CN101352483B CN2008101405071A CN200810140507A CN101352483B CN 101352483 B CN101352483 B CN 101352483B CN 2008101405071 A CN2008101405071 A CN 2008101405071A CN 200810140507 A CN200810140507 A CN 200810140507A CN 101352483 B CN101352483 B CN 101352483B
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Abstract
The invention discloses a compound Chinese patent medicine which is prepared by combining Chinese medicines and western medicines, in particular to a medicine used for treating diabetes mellitus. The medicine takes the western medicines with the function of lowering blood sugar and the Chinese medicines used for preventing and treating chronic complicating disease as the main ingredients, and the ingredients particularly include: 14-18g of radix astragali paste, 16-20g of radix puerariae powder, 10-14g of angelica paste, 0.1-1g of salvia miltiorrhiza paste, 1-4g of rhizoma atractylodis paste, 0.05-0.5g of glibenclamide powder and 1.25-3.75g of phenformin powder; the preparation method is as follows: high-quality medicinal materials of radix astragali, angelica, salvia miltiorrhiza and rhizoma atractylodis are selected and decocted with water for 2 times, one hour per time; the dreg is removed, and the juice is taken and stands still for 8-12 hours; after being clarified, supernatant fluid is taken and is decocted into paste; radix puerariae is pulverized and sieved by a 120 meshes fine screen to remove fibers and prepare powder; then radix astragali paste and angelica paste as well as radix puerariae powder, salvia miltiorrhiza paste and glibenclamide powder, rhizoma atractylodis paste and phenformin powder are evenly stirred respectively and prepared into dried granules which are loaded into capsules after being evenly blended. By adopting a traditional processing technique, the product of the invention contains a variety of medicine ingredients for reducing blood sugar and preventing and treating various complicating diseases, has precise prescription, long lasting drug effect, remarkable curative effect and safe and reliable performance.
Description
Technical field:
The present invention relates to a kind of compound Chinese patent medicine that combines and prepare with Chinese and western drugs, specifically is a kind of medicine for the treatment of diabetes.
Background technology:
Along with the significantly raising of people's living standard, the sickness rate of diabetes also raises year by year, and the hazardness of various complication, particularly chronic vascular complication becomes increasingly conspicuous, and has become " the 3rd killer " of serious threat human health.Only take at present blood sugar control and prevent and treat the complex treatment measure that complication is laid equal stress on, could reduce its hazardness.Western medicine has reliable blood sugar reducing function, greatly reduces the hazardness of acute complications, but has quite a few chronic complicating diseases to can not get effective control; Chinese medicine can effectively improve symptom, and the control chronic complicating diseases but often can not be with glycemic control to desirable level, and its effect that improves symptom, control chronic complicating diseases also is difficult to demonstrate fully, so that is difficult to find the Chinese medicine figure in " Chinese diabetes control guide ".The many pathogenesis prescriptions according to diabetes of present Chinese medicine and western medicine compound preparation add single Western medicine, and Chinese medicine lays particular emphasis on blood sugar lowering in the side, fail to demonstrate fully the advantage that it prevents and treats complication, and single Western medicine blood sugar reducing function is limited, and the scope of application also is subjected to significant limitation.Though phenformin has good blood sugar reducing function, the risk because of lactic acidosis is brought out in existence almost suffers exit.
Summary of the invention:
Purpose of the present invention has just provided utilizes Western medicine blood sugar lowering, Chinese herb prevention chronic complicating diseases, and a kind of medicine for the treatment of diabetes that the medicine source is wide, cost is low, duration of efficacy is long, evident in efficacy.The technical scheme that the present invention solves is based on motherland's medical science to diabetes and pathogenetic understanding of chronic complicating diseases and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland's medical treasure-house, filter out Chinese and western drugs, press the theory of medicine prescription, skim the cream off milk, reach the effect that development takes place control of diabetes.Described medicine is main prescription with Western medicine blood sugar lowering, Chinese herb prevention chronic complicating diseases, and concrete prescription is Radix Astragali cream 14-18g, powder of Radix Puerariae 16-20g, Radix Angelicae Sinensis cream 10-14g, danshen cream 0.1-1g, Rhizoma Atractylodis cream 1-4g, glibenclamide powder 0.05-0.5g and phenformin powder 1.25-3.75g; Preparation method decocts with water respectively 2 times for selecting the fine Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae and Rhizoma Atractylodis medical material, each 1 hour, gets supernatant after the extracting juice that removes slag leaves standstill and clarified in 8-12 hour and endures cream; Radix Puerariae is pulverized laggard row 120 order fine-structure meshes and is sieved and remove fiber powder process; Then Radix Astragali cream and Radix Angelicae Sinensis cream and powder of Radix Puerariae, danshen cream and glibenclamide powder, Rhizoma Atractylodis cream and phenformin powder are mixed thoroughly respectively make dried particles after mixing incapsulate.The present invention is owing to adopted several Chinese crude drugs and conventional machining process, its goods to include multiple blood sugar lowering and prevented and treated the ingredient of multiple complications, and prescription is rigorous, duration of efficacy is long and evident in efficacy, safe and reliable, have the effect for the treatment of multiple diabetes, removed patient's misery.
Pharmacology theory of the present invention is thought, the effect that the Chinese medicine astragalus in this prescription has QI invigorating, regulates immunity; Radix Angelicae Sinensis has the effect of enriching blood, invigorating blood circulation; Radix Salviae Miltiorrhizae has the effect of invigorating blood circulation; Radix Puerariae has microcirculation improvement, hypoglycemic effect.More than four the flavor 5 usefulness, can realize enriches blood invigorates blood circulation, microcirculation improvement is prevented and treated the chronic vascular complication that diabetes cause; Regulate immunologic function,, reduce glibenclamide secondary failure rate to stop carrying out property of beta Cell of islet apoptosis.The Western medicine glibenclamide then has the function that stimulates the beta Cell of islet excreting insulin; Phenformin has the effect that glycogen was exported, delayed the intestinal absorption glucose, strengthens insulin sensitivity that suppresses.The two coupling can enlarge the scope of application from the collaborative blood sugar reducing function of different link performances.Add Rhizoma Atractylodis, can improve gastrointestinal function, alleviate the untoward reaction of phenformin.The clinical more than ten years, do not find obvious toxic-side effects, safe and reliable.We respectively get its long, complementary its short principle prescription according to Chinese medicine and western medicine, give full play to the blood sugar lowering effect of Western medicine, the advantage of Chinese herb prevention chronic complicating diseases, take into account the gastrointestinal reaction that alleviates Western medicine with Chinese medicine, stop the glibenclamide secondary failure, adopt traditional method to make quick-acting, efficient, permanent Jiangtang capsule of imitating.It is good that the patient obeys aftersensation, and taking convenience, and moderate cost has improved the compliance of patient to treatment, share separately or with insulin, is applicable to and counts diabeticss extremely greatly.
The specific embodiment:
Described medicine is main prescription with Western medicine blood sugar lowering, Chinese herb prevention chronic complicating diseases, and concrete prescription is Radix Astragali cream 14-18g, powder of Radix Puerariae 16-20g, Radix Angelicae Sinensis cream 10-14g, danshen cream 0.1-1g, Rhizoma Atractylodis cream 1-4g, glibenclamide powder 0.05-0.5g and phenformin powder 1.25-3.75g; Preparation method decocts with water respectively 2 times for selecting the fine Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae and Rhizoma Atractylodis medical material, each 1 hour, gets supernatant after the extracting juice that removes slag leaves standstill and clarified in 8-12 hour and endures cream; Radix Puerariae is pulverized laggard row 120 order fine-structure meshes and is sieved and remove fiber powder process; Then Radix Astragali cream and Radix Angelicae Sinensis cream and powder of Radix Puerariae, danshen cream and glibenclamide powder, Rhizoma Atractylodis cream and phenformin powder are mixed thoroughly respectively make dried particles after mixing incapsulate.
Described medicine is main prescription with Western medicine blood sugar lowering, Chinese herb prevention chronic complicating diseases, and concrete prescription is Radix Astragali cream 15g, powder of Radix Puerariae 20g, Radix Angelicae Sinensis cream 12g, danshen cream 1g, Rhizoma Atractylodis cream 2.5g, glibenclamide powder 0.5g and phenformin powder 2.5g; Preparation method decocts with water respectively 2 times for selecting the fine Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae and Rhizoma Atractylodis medical material, each 1 hour, gets supernatant after the extracting juice that removes slag leaves standstill and clarified in 8-12 hour and endures cream; Radix Puerariae is pulverized laggard row 120 order fine-structure meshes and is sieved and remove fiber powder process; Then Radix Astragali cream and Radix Angelicae Sinensis cream and powder of Radix Puerariae, danshen cream and glibenclamide powder, Rhizoma Atractylodis cream and phenformin powder are mixed thoroughly respectively make dried particles after mixing incapsulate.
The preparation method of medicine of the present invention can suitably be adjusted the ratio of ointment and medicated powder according to indoor humidity, under the prerequisite that can make dried particles, increases the ointment proportion as far as possible; Also can adopt corresponding Chinese medicinal granule formulated in the proper ratio.
The capsule explosive payload of medicine of the present invention is 0.5 gram.
Embodiment 1: Li Yuhai, and the man, 61 years old, diabetes were suffered from more than 20 year by retired employees of crane coal group, beat insulin and ate all instabilities of other antidiabetic drug blood glucose, and curative effect is bad.Begin to take this medicine glucostasis so far in 2000, blood glucose phenomenon fluctuated do not occur, do not have other side effect.
Embodiment 2: Malaysian is rich, and 54 years old, Hebi City development zone cadre since 90 years suffer from diabetes, had treated in provincial hospital and the People's Hospital, Hebi, but had little effect, and has influenced work.From took in 96 years return the stilbene Jiangtang capsule since, existing glucostasis does not develop complications yet, work and life have recovered normal.
Embodiment 3: Fu Chunzheng, and the man, 64 years old, diabetes were suffered from 5 years by Hebi City First People's Hospital retired employees, and blood glucose 30 multiple spots during beginning are beaten insulin in hospital and are not all controlled to normally.The physician-in-charge says my obesity, and islets of langerhans is have resistance.I just leave hospital, and go outpatient service to look for doctor Li to make up a prescription, and blood glucose controls to normally very soon, do not have uncomfortable sensation.I only take a medicine now every day, and very convenient, the Fructus Cucumis flexuosi pear and date-printing blocks often eats, and blood glucose is not high yet, and spirit is very good, and the medicine that doctor Li joins is very effective.
Claims (2)
1. medicine for the treatment of diabetes, it is characterized in that this medicine is main prescription with Western medicine blood sugar lowering, Chinese herb prevention chronic complicating diseases, concrete prescription is Radix Astragali cream 14-18g, powder of Radix Puerariae 16-20g, Radix Angelicae Sinensis cream 10-14g, danshen cream 0.1-1g, Rhizoma Atractylodis cream 1-4g, glibenclamide powder 0.05-0.5g and phenformin powder 1.25-3.75g; Preparation method decocts with water respectively 2 times for selecting the fine Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae and Rhizoma Atractylodis medical material, each 1 hour, gets supernatant after the extracting juice that removes slag leaves standstill and clarified in 8-12 hour and endures cream; Radix Puerariae is pulverized laggard row 120 order fine-structure meshes and is sieved and remove fiber powder process; Then Radix Astragali cream and Radix Angelicae Sinensis cream and powder of Radix Puerariae, danshen cream and glibenclamide powder, Rhizoma Atractylodis cream and phenformin powder are mixed thoroughly respectively and made dried particles, will incapsulate behind above-mentioned three kinds of granule mixings again.
2. a kind of medicine for the treatment of diabetes according to claim 1, it is characterized in that this medicine is main prescription with Western medicine blood sugar lowering, Chinese herb prevention chronic complicating diseases, concrete prescription is Radix Astragali cream 15g, powder of Radix Puerariae 20g, Radix Angelicae Sinensis cream 12g, danshen cream 1g, Rhizoma Atractylodis cream 2.5g, glibenclamide powder 0.5g and phenformin powder 2.5g; Preparation method decocts with water respectively 2 times for selecting the fine Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae and Rhizoma Atractylodis medical material, each 1 hour, gets supernatant after the extracting juice that removes slag leaves standstill and clarified in 8-12 hour and endures cream; Radix Puerariae is pulverized laggard row 120 order fine-structure meshes and is sieved and remove fiber powder process; Then Radix Astragali cream and Radix Angelicae Sinensis cream and powder of Radix Puerariae, danshen cream and glibenclamide powder, Rhizoma Atractylodis cream and phenformin powder are mixed thoroughly respectively and made dried particles, will incapsulate behind above-mentioned three kinds of granule mixings again.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101405071A CN101352483B (en) | 2008-06-30 | 2008-06-30 | Medicine for treating diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101405071A CN101352483B (en) | 2008-06-30 | 2008-06-30 | Medicine for treating diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101352483A CN101352483A (en) | 2009-01-28 |
| CN101352483B true CN101352483B (en) | 2011-03-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101405071A Expired - Fee Related CN101352483B (en) | 2008-06-30 | 2008-06-30 | Medicine for treating diabetes |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104758414A (en) * | 2015-04-16 | 2015-07-08 | 叶宁 | Thirst-relieving traditional Chinese medicine preparation for treating diabetes |
| CN106727969A (en) * | 2016-11-08 | 2017-05-31 | 赖珅 | It is a kind of to treat antibiotic composition of diabetes and preparation method and application |
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2008
- 2008-06-30 CN CN2008101405071A patent/CN101352483B/en not_active Expired - Fee Related
Non-Patent Citations (5)
| Title |
|---|
| 刘华宝.加味降糖六味汤治疗糖尿病末梢神经病变42例.《陕西中医》.2005,第26卷(第12期),1320-1322. * |
| 朱炳辉 等.固相萃取/高效液相色谱法对中成药和保健品中7种降糖化学药物的测定.《分析测试学报》.2008,第27卷(第5期),534-537. |
| 朱炳辉等.固相萃取/高效液相色谱法对中成药和保健品中7种降糖化学药物的测定.《分析测试学报》.2008,第27卷(第5期),534-537. * |
| 李冰 等.中药降糖制剂非法掺入成分盐酸二甲双胍、盐酸苯乙双胍、格列齐特和格列本脲鉴别.《山东省药学会第一届学术年会论文集（上）》.2005,103-106. |
| 李冰等.中药降糖制剂非法掺入成分盐酸二甲双胍、盐酸苯乙双胍、格列齐特和格列本脲鉴别.《山东省药学会第一届学术年会论文集(上)》.2005,103-106. * |
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| CN101352483A (en) | 2009-01-28 |
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