CN101513492A - Chinese medicament for treating diabetes - Google Patents

Chinese medicament for treating diabetes Download PDF

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Publication number
CN101513492A
CN101513492A CNA2008100579748A CN200810057974A CN101513492A CN 101513492 A CN101513492 A CN 101513492A CN A2008100579748 A CNA2008100579748 A CN A2008100579748A CN 200810057974 A CN200810057974 A CN 200810057974A CN 101513492 A CN101513492 A CN 101513492A
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China
Prior art keywords
radix
parts
chinese medicine
diabetes
roots
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Pending
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CNA2008100579748A
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Chinese (zh)
Inventor
王丽娟
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BEIJING TIANKE RENXIANG MEDICAL SCI-TECH Co Ltd
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BEIJING TIANKE RENXIANG MEDICAL SCI-TECH Co Ltd
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Priority to CNA2008100579748A priority Critical patent/CN101513492A/en
Publication of CN101513492A publication Critical patent/CN101513492A/en
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Abstract

The invention discloses a Chinese medicament for treating diabetes. The Chinese medicament is prepared from twelve Chinese medicinal materials, namely codonopsis pilosula, red sage roots, figwort roots, astragalus roots, kudzuvine roots, achyranthes roots, ophiopogon roots, Chinese yams, hemlock parsley, medlar, cistanche salsa and hawthorn. The twelve Chinese medicinal materials are extracted, processed and prepared into power, granules, capsules, tablets and pills through grinding, mixing, water decoction, filtration, concentration, drying and other processes. The Chinese medicament has the efficacies in reinforcing stomach, promoting the production of body fluid, nourishing Yin, nourishing kidney, relieving restlessness and quenching thirst, is used for treating the diabetes, and has the advantages of rapidly recovering glucose metabolism, decreasing blood lipid, promoting insulin secretion and keeping blood glucose stable, along with good therapeutic effects and remarkable action.

Description

A kind of Chinese medicine for the treatment of diabetes
Technical field
The invention belongs to the Chinese medicine preparation technical field, be specifically related to a kind of Chinese medicine for the treatment of diabetes, and the formula combination and the preparation method of this Chinese medicine have been done correlational study.
Technical background
Diabetes are ancient disease.China the earliest the medical book Plain Questions of Huangdi's Internal Classic and Miraculous Pivot in just put down in writing " diabete " this name of disease.The piece of writing of quenching one's thirst of Han dynasty well-known doctor's Zhang Zhongjing " gold is deficient " is on the books to " more than three " symptom.Diabetes are because the h and E factor interaction, cause that absolute or relative hyposecretion of insulin and target tissue cell reduce insulin sensitivity, causing a series of metabolism disorder syndromes such as protein, fat, power and water Xie Zhi, wherein is outstanding feature with the hyperglycemia.Performance such as polyuria, polydipsia, polyphagia can appear in clinical model case, become thin, i.e. " three-many-one-little " symptom.
Diabetes are one of modal chronic diseases, with hypertension, coronary heart disease and tumor and claim four big Chronic Non-Communicable Diseasess of current threat human health.Along with the raising of people's living standard, the increase of aged tendency of population and fat incidence rate, the sickness rate of diabetes is ascendant trend year by year.Diabetes reach 2% at the sickness rate of China.According to statistics, the diabetics made a definite diagnosis of China reaches 4,000 ten thousand, and with annual 1000000 speed increase.Wherein, type 1 diabetes patient accounts for 10%, and the type 2 diabetes mellitus patient accounts for 90%.The appearance of chronic complicating diseases is seldom arranged in type 1 diabetes patient 5 years after making a definite diagnosis, and on the contrary, the type 2 diabetes mellitus patient had just had chronic complicating diseases to take place before making a definite diagnosis.According to statistics, there is the 50% new type 2 diabetes mellitus patient who diagnoses to have one or more chronic complicating diseases.Because the diabetes early symptom is not obvious, often can not cause patient's attention and delay treatment.
Diabetics shows polyuria, and thirsty polydipsia, and losing of saccharide makes people's polyorexia, weight loss.The heavier diabetes patient of the state of an illness since losing in a large number of nutrient substance show as and become thin, muscle weakness, the infection of respiratory tract, urinary tract and skin easily takes place in immunologic function degression, and restive, as merging foot ulcers, Chang Jingjiu is not healed, even the amputation of having to.Main harm is that then blood sugar concentration raises, and makes hyperlipidemia, and the time has been grown trunk and the microangiopathies that causes whole body.The macroangiopathy that diabetes merge mainly contains coronary heart disease and cerebrovascular, and the myocardial infarction of Fa Shenging, cerebral infarction and cerebral hemorrhage are to cause the diabetic main causes of death thus.The microangiopathies that diabetes merge mainly contains retinopathy and nephropathy and neuropathy, and acra symmetry numb pain, blurred vision, edema of lower limbs, albuminuria can appear in clinical manifestation, and serious causing lost one's sight and renal failure.
Diabetes are a kind of may command, but need metabolic disease long-term or that control throughout one's life.Oneself can be better up to standard for making by treatment, make blood glucose be able to strict control, prevent various acute and chronic complication, so, it is very necessary carrying out self-monitoring.The meaning of self-monitoring is to obtain blood glucose and for information about, and as adjusting medicine, the foundation of diet and activity is to improve more comprehensively to effective control of the state of an illness with to the regulating power of quality of life.
The method of treatment diabetes mainly contains Diet Therapy, oral antidiabetic drug and insulin etc. at present.Chinese medicine provided by the invention, remarkable, effective to the treatment diabetes curative effect, can recover function carbohydrate metabolism rapidly, blood fat reducing promotes insulin secretion, keeps glucostasis.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine for the treatment of diabetes, comprises its formula combination and preparation method.
Be achieved through the following technical solutions order of the present invention:
1, the present invention is the Chinese medicine of being made by the following weight proportion raw material:
Radix Codonopsis 20-200 part Radix Salviae Miltiorrhizae 20-200 part Radix Scrophulariae 20-200 part
Radix Astragali 50-250 part Radix Puerariae 30-150 part Radix Achyranthis Bidentatae 30-150 part
Radix Ophiopogonis 20-200 part Rhizoma Dioscoreae 20-200 part Rhizoma Chuanxiong 30-150 part
Fructus Lycii 50-250 part Herba Cistanches 30-150 part Fructus Crataegi 20-200 part
2, the present invention is the Chinese medicine of being made by following preferred weight proportion raw material:
Radix Codonopsis 30-120 part Radix Salviae Miltiorrhizae 30-120 part Radix Scrophulariae 30-120 part
Radix Astragali 80-200 part Radix Puerariae 50-100 part Radix Achyranthis Bidentatae 50-100 part
Radix Ophiopogonis 30-120 part Rhizoma Dioscoreae 30-120 part Rhizoma Chuanxiong 50-100 part
Fructus Lycii 80-200 part Herba Cistanches 50-100 part Fructus Crataegi 30-120 part
3, best each the raw material weight proportioning of prescription of the present invention is:
80 parts of 80 portions of Radix Scrophulariaes of 80 parts of Radix Salviae Miltiorrhizaes of Radix Codonopsis
65 parts of 65 parts of Radix Achyranthis Bidentataes of 120 parts of Radix Puerariaes of the Radix Astragali
65 parts of 80 parts of Rhizoma Chuanxiongs of 80 portions of Rhizoma Dioscoreaes Radix Ophiopogonis
80 parts of 65 portions of Fructus Crataegis of 120 parts of Herba Cistanches of Fructus Lycii
4, preparation method: be to get above pulverizing medicinal materials to become coarse powder, mix, the decocting that adds 6~12 times of medical material amounts boils 2~4 times, each 1~2 hour, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.35~1.42 thick paste, cold drying is pulverized, add an amount of starch or dextrin or lactose or the above adjuvant mixture under certain proportioning, make powder, granule, capsule, tablet or pill, packing, promptly.
The present invention is to be raw material with the Chinese medicine material, takes the formula combination that suits, through pulverizing, mixing, decocting, filtration, concentrate, technology such as drying extracts powder, granule, capsule, tablet or the pill of being processed into.Having reinforcing stomach reg fluid, YIN nourishing and support the effect that kidney, relieving restlessness quench the thirst, is to be used for the treatment of diabetes, good effect, and effect significantly can recover function carbohydrate metabolism rapidly, and blood fat reducing promotes insulin secretion, keeps glucostasis.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1
Prescription is formed:
Radix Codonopsis 80g Radix Salviae Miltiorrhizae 80g Radix Scrophulariae 80g
Radix Astragali 120g Radix Puerariae 65g Radix Achyranthis Bidentatae 65g
Radix Ophiopogonis 80g Rhizoma Dioscoreae 80g Rhizoma Chuanxiong 65g
Fructus Lycii 120g Herba Cistanches 65g Fructus Crataegi 80g
Preparation method: be to get above pulverizing medicinal materials to become coarse powder, mix that the decocting that adds 10 times of medical material amounts boils 3 times, each 1 hour, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.39 thick paste, cold drying is pulverized, and adds the about 110g of mixture of starch and dextrin (ratio is 3: 1), use 90% alcohol granulation, sieve, dry, granulate are made granule 360g, pack (every packed 6g) promptly gets granule.
Embodiment 2
Prescription is formed:
30 parts of 30 portions of Radix Scrophulariaes of 30 parts of Radix Salviae Miltiorrhizaes of Radix Codonopsis
50 parts of 50 parts of Radix Achyranthis Bidentataes of 80 parts of Radix Puerariaes of the Radix Astragali
50 parts of 30 parts of Rhizoma Chuanxiongs of 30 portions of Rhizoma Dioscoreaes Radix Ophiopogonis
30 parts of 50 portions of Fructus Crataegis of 80 parts of Herba Cistanches of Fructus Lycii
Preparation method: be to get above pulverizing medicinal materials to become coarse powder, mix that the decocting that adds 6 times of medical material amounts boils 2 times, each 1 hour, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.40 thick paste, cold drying is pulverized, cross 80~100 mesh sieves, packing promptly gets powder.
Embodiment 3
Prescription is formed:
50 parts of 50 portions of Radix Scrophulariaes of 50 parts of Radix Salviae Miltiorrhizaes of Radix Codonopsis
70 parts of 70 parts of Radix Achyranthis Bidentataes of 100 parts of Radix Puerariaes of the Radix Astragali
70 parts of 50 parts of Rhizoma Chuanxiongs of 50 portions of Rhizoma Dioscoreaes Radix Ophiopogonis
50 parts of 70 portions of Fructus Crataegis of 100 parts of Herba Cistanches of Fructus Lycii
Preparation method: be to get above pulverizing medicinal materials to become coarse powder, mix that the decocting that adds 8 times of medical material amounts boils 2 times, each 1.5 hours, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.39 thick paste, cold drying, pulverize, add the about 85g of mixture of dextrin and lactose (ratio is 1: 4), use 85% alcohol granulation, sieve, granulate in No. 0~No. 3 capsulae vacuuses of packing into, promptly gets capsule.
Embodiment 4:
Prescription is formed:
120 parts of 120 portions of Radix Scrophulariaes of 120 parts of Radix Salviae Miltiorrhizaes of Radix Codonopsis
100 parts of 100 parts of Radix Achyranthis Bidentataes of 200 parts of Radix Puerariaes of the Radix Astragali
100 parts of 120 parts of Rhizoma Chuanxiongs of 120 portions of Rhizoma Dioscoreaes Radix Ophiopogonis
120 parts of 100 portions of Fructus Crataegis of 200 parts of Herba Cistanches of Fructus Lycii
Preparation method: be to get above pulverizing medicinal materials to become coarse powder, mix that the decocting that adds 12 times of medical material amounts boils 4 times, each 1 hour, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.42 thick paste, cold drying, pulverize, sieve mixing, use water pill, drying, polishing promptly gets pill.

Claims (3)

1, a kind of Chinese medicine for the treatment of diabetes is characterized in that it is to be made by the raw material of part by following weight:
Radix Codonopsis 20-200 part Radix Salviae Miltiorrhizae 20-200 part Radix Scrophulariae 20-200 part
Radix Astragali 50-250 part Radix Puerariae 30-150 part Radix Achyranthis Bidentatae 30-150 part
Radix Ophiopogonis 20-200 part Rhizoma Dioscoreae 20-200 part Rhizoma Chuanxiong 30-150 part
Fructus Lycii 50-250 part Herba Cistanches 30-150 part Fructus Crataegi 20-200 part
This Chinese medicine is to get above medical material, mixes, and decocts with water, and filters, and merges decocting liquid and is condensed into thick paste, and drying is pulverized the Chinese medicine preparation of making.
2, a kind of Chinese medicine for the treatment of diabetes as claimed in claim 1 is characterized in that it is made by following preferred weight proportion raw material:
Radix Codonopsis 30-120 part Radix Salviae Miltiorrhizae 30-120 part Radix Scrophulariae 30-120 part
Radix Astragali 80-200 part Radix Puerariae 50-100 part Radix Achyranthis Bidentatae 50-100 part
Radix Ophiopogonis 30-120 part Rhizoma Dioscoreae 30-120 part Rhizoma Chuanxiong 50-100 part
Fructus Lycii 80-200 part Herba Cistanches 50-100 part Fructus Crataegi 30-120 part
This Chinese medicine is to get above pulverizing medicinal materials to become coarse powder, mix, the decocting that adds 6~12 times of medical material amounts boils 2~4 times, each 1~2 hour, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.35~1.42 thick paste, cold drying, pulverize, add the Chinese medicine preparation that suitable adjuvant is made suitable dosage forms.
3,, it is characterized in that it is made by following optimum weight proportion raw material as claim 1 and 2 described a kind of Chinese medicines for the treatment of diabetes:
80 parts of 80 portions of Radix Scrophulariaes of 80 parts of Radix Salviae Miltiorrhizaes of Radix Codonopsis
65 parts of 65 parts of Radix Achyranthis Bidentataes of 120 parts of Radix Puerariaes of the Radix Astragali
65 parts of 80 parts of Rhizoma Chuanxiongs of 80 portions of Rhizoma Dioscoreaes Radix Ophiopogonis
80 parts of 65 portions of Fructus Crataegis of 120 parts of Herba Cistanches of Fructus Lycii
This Chinese medicine is to get above medicinal material coarse powder, mix, the decocting that adds 10 times of medical material amounts boils 3 times, each 1 hour, filter respectively, merge decocting liquid and be condensed into 75 ℃ of heat that to survey relative densities be 1.39 thick paste, cold drying is pulverized, add an amount of starch or dextrin or lactose or the above adjuvant mixture under certain proportioning, make the arbitrary dosage form in powder, granule, capsule, tablet and the pill, packing, the Chinese medicine that promptly gets.
CNA2008100579748A 2008-02-22 2008-02-22 Chinese medicament for treating diabetes Pending CN101513492A (en)

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Application Number Priority Date Filing Date Title
CNA2008100579748A CN101513492A (en) 2008-02-22 2008-02-22 Chinese medicament for treating diabetes

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CN101513492A true CN101513492A (en) 2009-08-26

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912484A (en) * 2010-08-02 2010-12-15 魏青山 Chinese medicinal composition for treating hypertension, hyperlipidemia and hyperglycemia
CN102150779A (en) * 2011-03-24 2011-08-17 岑卫华 Health food for regulating and stabilizing blood sugar and preparation method thereof
CN103816345A (en) * 2012-11-19 2014-05-28 董根荣 Medicament for treating traumatic injury and preparation method thereof
CN104398687A (en) * 2014-12-10 2015-03-11 无锡瑞年实业有限公司 Capsule assisted for reducing blood fat
CN104398689A (en) * 2014-12-10 2015-03-11 无锡瑞年实业有限公司 Soft capsule used for helping blood fat reduction
CN104435433A (en) * 2014-12-10 2015-03-25 无锡瑞年实业有限公司 Composition for assisting reduction of blood fat

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912484A (en) * 2010-08-02 2010-12-15 魏青山 Chinese medicinal composition for treating hypertension, hyperlipidemia and hyperglycemia
CN102150779A (en) * 2011-03-24 2011-08-17 岑卫华 Health food for regulating and stabilizing blood sugar and preparation method thereof
CN102150779B (en) * 2011-03-24 2012-11-21 岑卫华 Health food for regulating and stabilizing blood sugar and preparation method thereof
CN103816345A (en) * 2012-11-19 2014-05-28 董根荣 Medicament for treating traumatic injury and preparation method thereof
CN104398687A (en) * 2014-12-10 2015-03-11 无锡瑞年实业有限公司 Capsule assisted for reducing blood fat
CN104398689A (en) * 2014-12-10 2015-03-11 无锡瑞年实业有限公司 Soft capsule used for helping blood fat reduction
CN104435433A (en) * 2014-12-10 2015-03-25 无锡瑞年实业有限公司 Composition for assisting reduction of blood fat

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20090826