CN101979054A - Traditional Chinese medicine for treating diabetic constipation - Google Patents
Traditional Chinese medicine for treating diabetic constipation Download PDFInfo
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- CN101979054A CN101979054A CN2010105281554A CN201010528155A CN101979054A CN 101979054 A CN101979054 A CN 101979054A CN 2010105281554 A CN2010105281554 A CN 2010105281554A CN 201010528155 A CN201010528155 A CN 201010528155A CN 101979054 A CN101979054 A CN 101979054A
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Abstract
Description
技术领域technical field
本发明属于治疗糖尿病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating diabetes.
背景技术Background technique
糖尿病性便秘是糖尿病常见的并发症之一。这种便秘往往非常顽固,治疗难度大。现有的旨在治疗糖尿病性便秘的中药,存在一些突出的问题:一是效果不够明显,二是见效比较迟缓,以致于糖尿病患者排便困难的问题长期得不到有效解决,大家对此不满意。Diabetic constipation is one of the common complications of diabetes. This type of constipation is often very stubborn and difficult to treat. There are some outstanding problems in the existing traditional Chinese medicine aimed at treating diabetic constipation: first, the effect is not obvious enough; .
针对上述提出的问题,本发明提供一种治疗糖尿病性便秘的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。Aiming at the above-mentioned problems, the present invention provides a Chinese medicine for treating diabetic constipation, which can solve the problem that the effect of traditional Chinese medicines in the past is not obvious enough, and the effect is relatively slow. , the advantage of quicker effect.
发明内容Contents of the invention
本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:
1、一种治疗糖尿病性便秘的中药,采用中药原料制备,配方为(按重量比):1, a kind of Chinese medicine for the treatment of diabetic constipation, adopts Chinese medicine raw material to prepare, and formula is (by weight):
知母5——15份 白芍6——18份 三七3——9份Anemarrhena 5——15 parts Bai Shao 6——18 parts Sanqi 3——9 parts
石斛5——15份 灵芝6——18份 当归6——18份Dendrobium 5—15 parts Ganoderma lucidum 6—18 parts Angelica 6—18 parts
郁李仁5——15份Yu Liren 5 - 15 servings
这种治疗糖尿病性便秘的中药是由下列方法制成的:This traditional Chinese medicine for treating diabetic constipation is made by the following method:
(1)按上述重量比,将灵芝用水提醇沉法提取灵芝多糖,工艺流程如下:将灵芝破碎成颗粒状,过40目筛→用1∶20的热水(95℃)浸提→浸提液减压、浓缩→用3倍体积的95%乙醇混合、静置10-12小时、离心→加75%的乙醇,沉淀多糖→烘干得灵芝多糖提取物细粉;(1) According to the above weight ratio, extract Ganoderma lucidum polysaccharides from Ganoderma lucidum with water extraction and alcohol precipitation method, the process is as follows: crush Ganoderma lucidum into granules, pass through a 40-mesh sieve → leaching with 1:20 hot water (95°C) → leaching Extract the liquid under reduced pressure, concentrate → mix with 3 times the volume of 95% ethanol, let stand for 10-12 hours, centrifuge → add 75% ethanol, precipitate polysaccharide → dry to obtain fine powder of Ganoderma lucidum polysaccharide extract;
(2)按上述重量比,将知母、白芍、石斛、当归、郁李仁经常规水提取工艺提取,制成提取物浸膏细粉;(2) According to the above weight ratio, Anemarrhena, Radix Paeoniae Alba, Dendrobium, Angelica Sinensis, and Yu Liren are extracted through a conventional water extraction process to make extract extract fine powder;
(3)按上述重量比,将三七研成细粉,与上述(1)、(2)两种提取物细粉混合,搅拌均匀,制成中药颗粒剂、胶囊剂、片剂。(3) According to the above weight ratio, grind Radix Notoginseng into a fine powder, mix with the fine powder of the above two kinds of extracts (1) and (2), stir evenly, and make traditional Chinese medicine granules, capsules, and tablets.
本发明根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。我们研究认为,凡糖尿病顽固便秘者都是免疫力严重低下者,正气不足,虚损严重,致阴液亏虚,虚热内生,耗灼津液,造成血液黏稠,肠供血不足,蠕动不力,此为该病的主要病理原因。所以,本发明以增强免疫力为重点,益气养血,活血化瘀,清热润肠通便。实践证实,这是一个治“本”的科学思路。本方之中灵芝、白芍扶正培本,益气养血,养心安神,增强机体免疫力,免疫力的“修复”功能是结肠恢复正常蠕动的关键因素;当归、三七生血养血,活血化瘀;臣以知母清热泻火,滋阴润燥;辅以石斛滋阴润肠,善治大便干燥;郁李仁润肠通便,尤宜治气滞肠燥之便秘。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀,润肠通便之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. According to our research, all diabetics with stubborn constipation are those with severely weakened immunity. Insufficient righteousness, severe deficiency, resulting in deficiency of Yin fluid, internal generation of deficiency heat, consumption of body fluid, resulting in thick blood, insufficient intestinal blood supply, and weak peristalsis. This is the main pathological cause of the disease. Therefore, the present invention focuses on enhancing immunity, replenishing qi and nourishing blood, promoting blood circulation and removing blood stasis, clearing away heat, moistening intestines and laxative. Practice has proved that this is a scientific way of treating the "root". In this prescription, Ganoderma lucidum and Paeoniae Alba strengthen the body, nourish qi and blood, nourish the heart and calm the nerves, enhance the body's immunity, and the "repair" function of immunity is the key factor for the colon to restore normal peristalsis; Angelica and Panax notoginseng produce blood and nourish blood , promote blood circulation and remove blood stasis; I use Zhimu to clear away heat and fire, nourish yin and moisten dryness; supplemented with Dendrobium to nourish yin and moisten the intestines, it is good at treating dry stool; Yu Liren moistens the intestines and laxatives, especially suitable for constipation caused by qi stagnation and intestinal dryness. All the medicines are compatible and complement each other, and they play the functions of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, moistening the intestines and laxative, with good effect and quick effect.
具体实施方式Detailed ways
通过以下实施方式对本发明做具体说明:The present invention is specifically described through the following embodiments:
1、取以下配方(重量按克为单位):1. Take the following formula (weight is in grams):
知母50克 白芍60克 三七30克Anemarrhena 50g Paeoniae Alba 60g Panax notoginseng 30g
石斛50克 灵芝60克 当归60克Dendrobium 50g Ganoderma lucidum 60g Angelica 60g
郁李仁50克Yu Liren 50g
按规定重量,用水提醇沉法将灵芝进行提取;用常规水提取工艺将知母、白芍、石斛、当归、郁李仁提取,共制成提取物细粉66克,将三七研成细粉,与上述提取物细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊342粒,每粒胶囊内含中药细粉及提取物0.28克。According to the specified weight, extract Ganoderma lucidum by water extraction and alcohol precipitation method; use conventional water extraction process to extract Anemarrhena, Radix Paeoniae Alba, Dendrobium, Angelica, and Yu Liren to make a total of 66 grams of extract fine powder, and grind Sanqi into fine powder , mixed with the above-mentioned extract fine powder, stirred evenly, made into fine particles, packed into No. 0 capsules, and made into 342 Chinese medicine capsules, each capsule containing Chinese medicine fine powder and 0.28 grams of extract.
2、取以下配方(重量按克为单位):2. Take the following formula (weight is in grams):
知母100克 白芍120克 三七60克Anemarrhena 100g Paeoniae Alba 120g Panax notoginseng 60g
石斛100克 灵芝120克 当归120克Dendrobium 100g Ganoderma lucidum 120g Angelica 120g
郁李仁100克Yu Liren 100g
按上述同样的方法,制成中药胶囊685粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 685 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.
3、取以下配方(重量按克为单位):3. Take the following formula (the weight is in grams):
知母150克 白芍180克 三七90克Anemarrhena 150g White peony root 180g Sanqi 90g
石斛150克 灵芝180克 当归180克Dendrobium 150g Ganoderma lucidum 180g Angelica 180g
郁李仁150克Yu Liren 150g
按上述同样的方法,制成中药胶囊1028粒,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, 1028 Chinese medicine capsules were made, and each capsule contained Chinese medicine fine powder and 0.28 grams of extract.
4、取以下配方(按重量比):4. Take the following formula (by weight):
知母7份 白芍9份 三七4份Anemarrhena 7 parts White peony root 9 parts Panax notoginseng 4 parts
石斛7份 灵芝9份 当归9份Dendrobium 7 parts Ganoderma lucidum 9 parts Angelica 9 parts
郁李仁7份Yu Liren 7 copies
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
5、取以下配方(按重量比):5. Take the following formula (by weight):
知母14份 白芍17份 三七8份14 parts Anemarrhena 17 parts Baishao 8 parts Panax notoginseng
石斛14份 灵芝17份 当归17份Dendrobium 14 parts Ganoderma lucidum 17 parts Angelica 17 parts
郁李仁14份Yu Liren 14 copies
按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.
临床资料:clinical information:
本发明以中医糖尿病性便秘为例,经8例临床观察。选择中医诊断糖尿病性便秘为标准:糖尿病患者神疲乏力,排便时间延长,解出困难或3日以上排便一次,粪便干燥坚硬。如上症状,即可确诊。在确诊观察的对象中,男性5例,女性3例,无其它严重疾病,年龄为47岁-75岁,平均年龄63.7岁。The present invention takes TCM diabetic constipation as an example, through clinical observation of 8 cases. The criteria for TCM diagnosis of diabetic constipation are: diabetic patients are fatigued, have prolonged defecation time, have difficulty defecating or defecate more than once every 3 days, and the stool is dry and hard. The above symptoms can be diagnosed. Among the objects under confirmed observation, there were 5 males and 3 females, without other serious diseases, aged from 47 to 75 years old, with an average age of 63.7 years.
疗效判定:Judgment of curative effect:
1、显效:体质增强,肢体有力;排便困难明显缓解,大便基本一天一次,便出顺畅。1. Significant effect: Physical fitness is enhanced, limbs are strong; difficulty in defecation is obviously relieved, and the stool is basically once a day, and the stool is smooth.
2、有效:体质增强,排便困难有所缓解。2. Effective: physical fitness is enhanced, and difficulty in defecation is relieved.
3、无效:病症无变化。3. Ineffective: no change in symptoms.
临床实验时,除降糖药照常服用外,停服其它药物和保健营养品。服用本发明中药胶囊,观察3个月为一个疗程。服用方法:每日2次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,1个月后症状即有缓解,服用3个月后,症状明显改善。临床实验的8中,显效4人,有效3人,无效1人,总有效率87.5%。During the clinical trial, except for the hypoglycemic drugs, stop taking other drugs and health nutrition products. Take Chinese medicine capsule of the present invention, observe 3 months and be a course of treatment. Dosing method: 2 times a day, 4 capsules each time, each capsule contains 0.28 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 3 months of taking, Symptoms improved significantly. Among the 8 clinical trials, 4 people were markedly effective, 3 people were effective, and 1 person was ineffective, with a total effective rate of 87.5%.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102380040A (en) * | 2011-07-23 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic constipation |
| CN102631534A (en) * | 2012-04-04 | 2012-08-15 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic constipation |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102380040A (en) * | 2011-07-23 | 2012-03-21 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic constipation |
| CN102631534A (en) * | 2012-04-04 | 2012-08-15 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic constipation |
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Application publication date: 20110223 |