CN105770136A - Traditional Chinese medicine composition for treating canine parvovirus and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating canine parvovirus and preparation method thereof Download PDFInfo
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Abstract
The invention provides traditional Chinese medicine composition for treating canine parvovirus and a preparation method thereof. The traditional Chinese medicine composition is a decoction, pills or powder prepared by sanguisorba officinalis, cortex phellodendri, rhizoma coptidis, lonicera japonica, fructus forsythia, radix scutellariae, angelica sinensis, rhizoma atractylodis macrocephalae, radix codonopsis, radix astragali, radix pueraiae, longan pulp and prepared radix glycyrrhizae. The traditional Chinese medicine composition can fast cure the canine parvovirus of canid, and drug tolerance of the canid can be avoided due to the fact that the traditional Chinese medicine composition is made of pure traditional Chinese medicine raw materials. Meanwhile, the traditional Chinese medicine composition can effectively prevent the canine parvovirus and increase the resistance of the canid.
Description
Technical field
The invention belongs to application in TCM technical field, particularly relate to a kind of Chinese medicine composition medicament treating Canine Parvovirus and preparation method.
Background technology
Canine Parvovirus is that the Kelly and Canadian Thomson etc. of Australia in 1978 separate from the sick dog feces suffering from enteritis simultaneously and obtain, and from finding this virus so far, all has popular all over the world, is one of topmost deadly infectious disease endangering dog class；It is the dog acute infectious disease caused by canine parvoviral enteritis, and its clinical manifestation has 2 types, i.e. enteritis type and myocarditis type.Enteritis type is comparatively common.Principal character has first vomits, and suffers from diarrhoea afterwards, in yellow or lark at the beginning of feces, then transfers Fructus Lycopersici esculenti juice sample to, and abnormal smells from the patient is smelt as of rotten fish；After present obvious dewatering symptom, weak, become thin, spirit depressed, enophthalmos,enophthalmus, skin elasticity reduce, slack anus, have blood in stool, fall down to the ground stupor；Finally can be dead because of the concurrent acidosis of electrolyte disturbance.Primary disease is mainly in the pup at 5 monthly ages below, and adult dogs is sent out less.At present, Western medicine many employings ribavirin, penicillin, gentamycin, dexamethasone, hemorrhage, vitamin B, vitamin C and symptomatic therapy, but easily develop immunity to drugs, though can quickly induce sweat, but mediation body function aspect does not have effect.So, better therapeutic scheme selects Chinese medicine to treat, and the patent of invention " a kind of compound Chinese medicinal preparation treating canine parvoviral enteritis and preparation method thereof " if application number is CN200910255681.5 discloses the use of the combined traditional Chinese medicine of the Radix Pulsatillae, Herba Portulacae, Rhizoma Coptidis, Cortex Phellodendri, Cortex Fraxini, the Radix Astragali, Rhizoma Dioscoreae, Radix Angelicae Sinensis, the Radix Aucklandiae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) and Radix Sanguisorbae and carries out treatment Canine Parvovirus；Its shortcoming is to take effect slowly.Also have and use the method that Chinese and Western combines to treat；Patent of invention " a kind of Chinese and western medicinal composition treating canine parvovirus disease and preparation method thereof " if application number is CN200910070289.3 discloses the use of Radix Puerariae, Rhizoma Coptidis, Radix Scutellariae 15-30 part, Cortex Phellodendri, Radix Et Rhizoma Rhei, hoary hair, Radix Sanguisorbae, Rhizoma Alismatis, the Radix Paeoniae Alba, the compositions treatment of Fructus Chebulae and ofloxacin；This Chinese and western medicinal composition toxicity is little, can effectively play the preventive and therapeutic action to canine parvovirus disease.
Summary of the invention
For solving above-mentioned technical problem, the invention provides a kind of Chinese medicine composition medicament treating Canine Parvovirus and preparation method.
The present invention is achieved by the following technical programs.
A kind of Chinese medicine composition medicament treating Canine Parvovirus provided by the invention, this Chinese medicine composition medicament includes the raw material of following weight portion: Radix Sanguisorbae 5-20 part, Cortex Phellodendri 5-20 part, Rhizoma Coptidis 5-15 part, Flos Lonicerae 5-20 part, Fructus Forsythiae 5-20 part, Radix Scutellariae 5-20 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Radix Codonopsis 5-15 part, Radix Astragali 5-10 part, Radix Puerariae 5-20 part, Arillus Longan 5-10 part, Radix Glycyrrhizae Preparata 5-20 part.
Further, this Chinese medicine composition medicament includes the raw material of following weight portion: Radix Sanguisorbae 10-15 part, Cortex Phellodendri 10-15 part, Rhizoma Coptidis 8-12 part, Flos Lonicerae 10-15 part, Fructus Forsythiae 10-15 part, Radix Scutellariae 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Codonopsis 8-12 part, Radix Astragali 6-9 part, Radix Puerariae 10-15 part, Arillus Longan 6-9 part, Radix Glycyrrhizae Preparata 10-15 part.
Further, this Chinese medicine composition medicament includes the raw material of following weight portion: Radix Sanguisorbae 14 parts, Cortex Phellodendri 11 parts, Rhizoma Coptidis 9 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 10 parts, Radix Scutellariae 12 parts, Radix Angelicae Sinensis 13 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, Radix Codonopsis 10 parts, the Radix Astragali 7 parts, Radix Puerariae 14 parts, Arillus Longan 8 parts, Radix Glycyrrhizae Preparata 14 parts.
Meanwhile, the preparation method that present invention also offers a kind of Chinese medicine composition medicament treating Canine Parvovirus, comprise the following steps:
1) all raw materials are proportionally mixed, then soak more than 2h；
2) after raw material being picked up, by clean water, then according to weight ratio: raw material: water=1:(3～5) ratio mixing boil, stop when the 80～150% of the volume only remaining raw material weight of water, filter, obtain filtrate for this Chinese medicine composition medicament.
Meanwhile, the preparation method that present invention also offers a kind of Chinese medicine composition medicament treating Canine Parvovirus, comprise the following steps:
1) all raw materials are proportionally mixed, then soak more than 2h；
2), after being picked up by raw material, by clean water, lixiviate is then carried out；Filter after lixiviate, obtain filtrate；Undertaken being condensed into extractum by this filtrate；
3) adjuvant of the 50～150% of addition extractum weight, is fabricated to the pill of 0.1～0.5g.
Further, described lixiviate is flooding, particularly as follows: the water of 5～10 times of meterings of s1, addition raw material weight boils, stops when weight is raw material 2～3 times of water；S2, it is filtrated to get filtrate, then boils again and be condensed into extractum.
Further, described lixiviate is alcohol steep, particularly as follows: the dehydrated alcohol of 3～5 times of meterings of s1, addition raw material weight carries out lixiviate, extraction temperature is 50～65 DEG C, extraction time is more than 20h, s2, add ethanol volume 30～100% water boil, the time is more than 1h, is then filtrated to get filtrate；S3, it is filtrated to get filtrate, then boils again and be condensed into extractum.
Further, described adjuvant is: at least one in Mel, Cera Flava, gelatinized corn starch, rice paste.
Meanwhile, the preparation method that present invention also offers a kind of Chinese medicine composition medicament treating Canine Parvovirus, comprise the following steps: grind into powder after all raw materials are proportionally mixed；Then more than decatize 1h again；Through super-dry, namely obtain this Chinese medicine composition medicament.
The beneficial effects of the present invention is: use Chinese medicine composition medicament provided by the invention can the canine parvovirus of rapid healing Canis animals, use the raw material of pure Chinese medicine simultaneously, Canis animals will not be made to develop immunity to drugs；Simultaneously use Chinese medicine composition medicament can preventing canine parvovirus, improve Canis animals resistance.
Detailed description of the invention
Technical scheme be described further below, but described in the scope claimed is not limited to.
Embodiment one
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 50g, Cortex Phellodendri 50g, Rhizoma Coptidis 50g, Flos Lonicerae 50g, Fructus Forsythiae 50g, Radix Scutellariae 50g, Radix Angelicae Sinensis 50g, Rhizoma Atractylodis Macrocephalae 50g, Radix Codonopsis 50g, Radix Astragali 50g, Radix Puerariae 50g, Arillus Longan 50g, Radix Glycyrrhizae Preparata 50g.Its preparation method is: 1) proportionally mixed by all raw materials, then soaks more than 2h；2) after raw material being picked up, by clean water, then according to weight ratio: raw material: the ratio mixing of water=1:3 is boiled, stop when the 80% of the volume only remaining raw material weight of water, filter, obtain filtrate for this Chinese medicine composition medicament.
This Chinese medicine composition medicament applies to treat the Canis animals of infected dogs parvovirus, three times on the one, gavage this medicament of 10～15ml every time, show through overtesting: use this Chinese medicine composition pharmaceutical treatment Canine Parvovirus, the Canis animals vomiting of more than 97% stopped the same day, 3rd day, the Canis animals of more than 96%, hemafecia lighter；5th day, the Canis animals temperature recovery of more than 99% was normal, stopped diarrhoea.
Embodiment two
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 200g, Cortex Phellodendri 200g, Rhizoma Coptidis 150g, Flos Lonicerae 50-200g, Fructus Forsythiae 200g, Radix Scutellariae 200g, Radix Angelicae Sinensis 150g, Rhizoma Atractylodis Macrocephalae 200g, Radix Codonopsis 150g, Radix Astragali 100g, Radix Puerariae 200g, Arillus Longan 100g, Radix Glycyrrhizae Preparata 200g.Its preparation method is: 1) proportionally mixed by all raw materials, then soaks more than 2h；2) after raw material being picked up, by clean water, then according to weight ratio: raw material: the ratio mixing of water=1:5 is boiled, stop when the 150% of the volume only remaining raw material weight of water, filter, obtain filtrate for this Chinese medicine composition medicament.
This Chinese medicine composition medicament applies to treat the Canis animals of infected dogs parvovirus, three times on the one, gavage this medicament of 10～15ml every time, show through overtesting: use this Chinese medicine composition pharmaceutical treatment Canine Parvovirus, the Canis animals vomiting of more than 97% stopped the same day, 3rd day, the Canis animals of more than 96%, hemafecia lighter；5th day, the Canis animals temperature recovery of more than 99% was normal, stopped diarrhoea.
Embodiment three
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 100g, Cortex Phellodendri 100g, Rhizoma Coptidis 80g, Flos Lonicerae 100g, Fructus Forsythiae 100g, Radix Scutellariae 100g, Radix Angelicae Sinensis 100g, Rhizoma Atractylodis Macrocephalae 100g, Radix Codonopsis 80g, Radix Astragali 60g, Radix Puerariae 100g, Arillus Longan 60g, Radix Glycyrrhizae Preparata 100g.Its preparation method is:.
1) all raw materials are proportionally mixed, then soak more than 2h；
2), after being picked up by raw material, by clean water, lixiviate is then carried out；Filter after lixiviate, obtain filtrate；Undertaken being condensed into extractum by this filtrate；Described lixiviate is flooding, particularly as follows: the water of 5～10 times of meterings of s1, addition raw material weight boils, stops when weight is raw material 2～3 times of water；S2, it is filtrated to get filtrate, then boils again and be condensed into extractum；
3) adjuvant of the 50% of addition extractum weight, is fabricated to the pill of 0.1g, and described adjuvant is: at least one in Mel, Cera Flava, gelatinized corn starch, rice paste.The present embodiment selects the mixture of Mel and gelatinized corn starch equal proportion.
This Chinese medicine composition medicament applies to treat the Canis animals of infected dogs parvovirus, three times on the one, each a piece of pill, show through overtesting: use this Chinese medicine composition pharmaceutical treatment Canine Parvovirus, the Canis animals vomiting of more than 95% stopped the same day, 3rd day, the Canis animals of more than 93%, hemafecia lighter；5th day, the Canis animals temperature recovery of more than 99% was normal, stopped diarrhoea.
Embodiment four
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 150g, Cortex Phellodendri 150g, Rhizoma Coptidis 120g, Flos Lonicerae 150g, Fructus Forsythiae 150g, Radix Scutellariae 150g, Radix Angelicae Sinensis 150g, Rhizoma Atractylodis Macrocephalae 150g, Radix Codonopsis 120g, Radix Astragali 90g, Radix Puerariae 150g, Arillus Longan 90g, Radix Glycyrrhizae Preparata 150g.Its preparation method is:.
1) all raw materials are proportionally mixed, then soak more than 2h；
2), after being picked up by raw material, by clean water, lixiviate is then carried out；Filter after lixiviate, obtain filtrate；Undertaken being condensed into extractum by this filtrate；Described lixiviate is flooding, particularly as follows: the water of 10 times of meterings of s1, addition raw material weight boils, stops when weight is raw material 3 times of water；S2, it is filtrated to get filtrate, then boils again and be condensed into extractum；
3) adjuvant of the 150% of addition extractum weight, is fabricated to the pill of 0.5g, and described adjuvant is: at least one in Mel, Cera Flava, gelatinized corn starch, rice paste；The present embodiment selects Cera Flava to stick with paste the mixture of equal proportion with rice.
This Chinese medicine composition medicament applies to treat the Canis animals of infected dogs parvovirus, three times on the one, each a piece of pill, show through overtesting: use this Chinese medicine composition pharmaceutical treatment Canine Parvovirus, the Canis animals vomiting of more than 98% stopped the same day, 3rd day, the Canis animals of more than 95%, hemafecia lighter；5th day, the Canis animals temperature recovery of more than 99% was normal, stopped diarrhoea.
Embodiment five
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 140g, Cortex Phellodendri 110g, Rhizoma Coptidis 90g, Flos Lonicerae 150g, Fructus Forsythiae 100g, Radix Scutellariae 120g, Radix Angelicae Sinensis 130g, Rhizoma Atractylodis Macrocephalae 110g, Radix Codonopsis 100g, Radix Astragali 70g, Radix Puerariae 140g, Arillus Longan 80g, Radix Glycyrrhizae Preparata 140g.Its preparation method is:.
1) all raw materials are proportionally mixed, then soak more than 2h；
2), after being picked up by raw material, by clean water, lixiviate is then carried out；Filter after lixiviate, obtain filtrate；Undertaken being condensed into extractum by this filtrate；Described lixiviate is flooding, particularly as follows: the water of 5～10 times of meterings of s1, addition raw material weight boils, stops when weight is raw material 2～3 times of water；S2, it is filtrated to get filtrate, then boils again and be condensed into extractum；
3) adjuvant of the 100% of addition extractum weight, is fabricated to the pill of 0.3g, and described adjuvant is: at least one in Mel, Cera Flava, gelatinized corn starch, rice paste, the present embodiment selects the mixture of Cera Flava and gelatinized corn starch equal proportion.
This Chinese medicine composition medicament applies to treat the Canis animals of infected dogs parvovirus, three times on the one, each a piece of pill, show through overtesting: use this Chinese medicine composition pharmaceutical treatment Canine Parvovirus, the Canis animals vomiting of more than 98% stopped the same day, 3rd day, the Canis animals of more than 95%, hemafecia lighter；5th day, the Canis animals temperature recovery of more than 99% was normal, stopped diarrhoea.
Embodiment six
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 140g, Cortex Phellodendri 110g, Rhizoma Coptidis 90g, Flos Lonicerae 150g, Fructus Forsythiae 100g, Radix Scutellariae 120g, Radix Angelicae Sinensis 130g, Rhizoma Atractylodis Macrocephalae 110g, Radix Codonopsis 100g, Radix Astragali 70g, Radix Puerariae 140g, Arillus Longan 80g, Radix Glycyrrhizae Preparata 140g.Its preparation method is:.
1) all raw materials are proportionally mixed, then soak more than 2h；
2), after being picked up by raw material, by clean water, lixiviate is then carried out；Filter after lixiviate, obtain filtrate；Undertaken being condensed into extractum by this filtrate；Described lixiviate is alcohol steep, particularly as follows: the dehydrated alcohol of 3～5 times of meterings of s1, addition raw material weight carries out lixiviate, extraction temperature is 50～65 DEG C, extraction time is more than 20h, s2, add ethanol volume 30～100% water boil, time is more than 1h, is then filtrated to get filtrate；S3, it is filtrated to get filtrate, then boils again and be condensed into extractum；
3) adjuvant of the 100% of addition extractum weight, is fabricated to the pill of 0.3g, and described adjuvant is: at least one in Mel, Cera Flava, gelatinized corn starch, rice paste, the present embodiment selects the mixture of Cera Flava and gelatinized corn starch equal proportion.
This Chinese medicine composition medicament applies to treat the Canis animals of infected dogs parvovirus, three times on the one, each a piece of pill, show through overtesting: use this Chinese medicine composition pharmaceutical treatment Canine Parvovirus, the Canis animals vomiting of more than 98% stopped the same day, 3rd day, the Canis animals of more than 95%, hemafecia lighter；5th day, the Canis animals temperature recovery of more than 99% was normal, stopped diarrhoea.
Embodiment seven
The present embodiment provides a kind of Chinese medicine composition medicament treating Canine Parvovirus, and this Chinese medicine composition medicament includes following raw material: Radix Sanguisorbae 140g, Cortex Phellodendri 110g, Rhizoma Coptidis 90g, Flos Lonicerae 150g, Fructus Forsythiae 100g, Radix Scutellariae 120g, Radix Angelicae Sinensis 130g, Rhizoma Atractylodis Macrocephalae 110g, Radix Codonopsis 100g, Radix Astragali 70g, Radix Puerariae 140g, Arillus Longan 80g, Radix Glycyrrhizae Preparata 140g.Its preparation method is: grind into powder after proportionally being mixed by all raw materials；Then more than decatize 1h again；Through super-dry, namely obtain this Chinese medicine composition medicament.
This Chinese medicine composition medicament applies to the prevention of Canine Parvovirus, specifically used method is, the daily grain of Canis animals adds this Chinese medicine composition medicament of 5～10g, the Canis animals resistance to Canine Parvovirus can be improved, show through overtesting, using the Canis animals of this medicament, it is possible to reduce the infection of Canine Parvovirus, the sickness rate of Canine Parvovirus reduces by more than 60%.
Claims (9)
1. the Chinese medicine composition medicament treating Canine Parvovirus, it is characterised in that: this Chinese medicine composition medicament includes the raw material of following weight portion: Radix Sanguisorbae 5-20 part, Cortex Phellodendri 5-20 part, Rhizoma Coptidis 5-15 part, Flos Lonicerae 5-20 part, Fructus Forsythiae 5-20 part, Radix Scutellariae 5-20 part, Radix Angelicae Sinensis 5-15 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Radix Codonopsis 5-15 part, Radix Astragali 5-10 part, Radix Puerariae 5-20 part, Arillus Longan 5-10 part, Radix Glycyrrhizae Preparata 5-20 part.
2. the Chinese medicine composition medicament treating Canine Parvovirus as claimed in claim 1, it is characterised in that: this Chinese medicine composition medicament includes the raw material of following weight portion: Radix Sanguisorbae 10-15 part, Cortex Phellodendri 10-15 part, Rhizoma Coptidis 8-12 part, Flos Lonicerae 10-15 part, Fructus Forsythiae 10-15 part, Radix Scutellariae 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Radix Codonopsis 8-12 part, Radix Astragali 6-9 part, Radix Puerariae 10-15 part, Arillus Longan 6-9 part, Radix Glycyrrhizae Preparata 10-15 part.
3. the Chinese medicine composition medicament application treating Canine Parvovirus as claimed in claim 1, it is characterised in that: this Chinese medicine composition medicament includes the raw material of following weight portion: Radix Sanguisorbae 14 parts, Cortex Phellodendri 11 parts, Rhizoma Coptidis 9 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 10 parts, Radix Scutellariae 12 parts, Radix Angelicae Sinensis 13 parts, the Rhizoma Atractylodis Macrocephalae 11 parts, Radix Codonopsis 10 parts, the Radix Astragali 7 parts, Radix Puerariae 14 parts, Arillus Longan 8 parts, Radix Glycyrrhizae Preparata 14 parts.
4. the preparation method of the Chinese medicine composition medicament of the treatment Canine Parvovirus as described in claims 1 to 3, it is characterised in that comprise the following steps:
1) all raw materials are proportionally mixed, then soak more than 2h；
2) after raw material being picked up, by clean water, then according to weight ratio: raw material: water=1:(3～5) ratio mixing boil, stop when the 80～150% of the volume only remaining raw material weight of water, filter, obtain filtrate for this Chinese medicine composition medicament.
5. the preparation method of the Chinese medicine composition medicament of the treatment Canine Parvovirus as described in claims 1 to 3, it is characterised in that comprise the following steps:
1) all raw materials are proportionally mixed, then soak more than 2h；
2), after being picked up by raw material, by clean water, lixiviate is then carried out；Filter after lixiviate, obtain filtrate；Undertaken being condensed into extractum by this filtrate；
3) adjuvant of the 50～150% of addition extractum weight, is fabricated to the pill of 0.1～0.5g.
6. the preparation method of the Chinese medicine composition medicament treating Canine Parvovirus as claimed in claim 5, it is characterized in that: described lixiviate is flooding, particularly as follows: the water of 5～10 times of meterings of s1, addition raw material weight boils, stop when weight is raw material 2～3 times of water；S2, it is filtrated to get filtrate, then boils again and be condensed into extractum.
7. the Chinese medicine composition medicament treating Canine Parvovirus as claimed in claim 5 and preparation method, it is characterized in that: described lixiviate is alcohol steep, particularly as follows: the dehydrated alcohol of 3～5 times of meterings of s1, addition raw material weight carries out lixiviate, extraction temperature is 50～65 DEG C, extraction time is more than 20h, s2, add ethanol volume 30～100% water boil, the time is more than 1h, is then filtrated to get filtrate；S3, it is filtrated to get filtrate, then boils again and be condensed into extractum.
8. the Chinese medicine composition medicament treating Canine Parvovirus as claimed in claim 5 and preparation method, it is characterised in that: described adjuvant is: at least one in Mel, Cera Flava, gelatinized corn starch, rice paste.
9. the preparation method of the Chinese medicine composition medicament of the treatment Canine Parvovirus as described in claims 1 to 3, it is characterised in that comprise the following steps: grind into powder after all raw materials are proportionally mixed；Then more than decatize 1h again；Through super-dry, namely obtain this Chinese medicine composition medicament.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108030815A (en) * | 2017-12-08 | 2018-05-15 | 重庆昇顺科技有限公司 | The composition, freeze-dried powder and preparation method of a kind of anti-parvovirus of fowl |
| CN109395041A (en) * | 2018-12-18 | 2019-03-01 | 丹东瑞丰动物药业有限责任公司 | A kind of Chinese medicine and preparation method thereof for treating dog tonsillitis |
| CN113499360A (en) * | 2021-08-28 | 2021-10-15 | 简建设 | Antidiarrheal Chinese herbal medicine composition and preparation method thereof |
| CN113730481A (en) * | 2021-08-24 | 2021-12-03 | 河北锦坤动物药业有限公司 | Traditional Chinese medicine composition for preventing and treating canine parvovirus enteritis, suppository and preparation method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101411762A (en) * | 2007-10-19 | 2009-04-22 | 天津生机集团有限公司 | Chinese medicinal composition for treating Canine parvovirus disease and preparation thereof |
-
2016
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101411762A (en) * | 2007-10-19 | 2009-04-22 | 天津生机集团有限公司 | Chinese medicinal composition for treating Canine parvovirus disease and preparation thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108030815A (en) * | 2017-12-08 | 2018-05-15 | 重庆昇顺科技有限公司 | The composition, freeze-dried powder and preparation method of a kind of anti-parvovirus of fowl |
| CN109395041A (en) * | 2018-12-18 | 2019-03-01 | 丹东瑞丰动物药业有限责任公司 | A kind of Chinese medicine and preparation method thereof for treating dog tonsillitis |
| CN113730481A (en) * | 2021-08-24 | 2021-12-03 | 河北锦坤动物药业有限公司 | Traditional Chinese medicine composition for preventing and treating canine parvovirus enteritis, suppository and preparation method |
| CN113730481B (en) * | 2021-08-24 | 2022-12-20 | 河北锦坤动物药业有限公司 | Traditional Chinese medicine composition for preventing and treating canine parvovirus enteritis, suppository and preparation method |
| CN113499360A (en) * | 2021-08-28 | 2021-10-15 | 简建设 | Antidiarrheal Chinese herbal medicine composition and preparation method thereof |
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