CN101411801A - Method for preparing Chinese medicinal composition for anti-abortion and formulation thereof - Google Patents

Method for preparing Chinese medicinal composition for anti-abortion and formulation thereof Download PDF

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Publication number
CN101411801A
CN101411801A CNA2007100561665A CN200710056166A CN101411801A CN 101411801 A CN101411801 A CN 101411801A CN A2007100561665 A CNA2007100561665 A CN A2007100561665A CN 200710056166 A CN200710056166 A CN 200710056166A CN 101411801 A CN101411801 A CN 101411801A
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weight portions
radix
charred
weight
person adds
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李蓉杰
王天骄
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Abstract

The invention discloses a traditional Chinese medicine for treating habitual abortion. The traditional Chinese medicine is prepared from charred cortex eucommiae, radices dipsaci, yam, angelica, prepared rehmannia root, radix paeoniae alba with vino, rhizoma ligustici wallichi, liquorice and other Chinese herbal medicines; and according to different symptoms, the amounts of the Chinese herbal medicines are added or reduced. The invention also discloses a method for preparing the preparation and belongs to the technical field of traditional Chinese medicine.

Description

A kind of preparation method that is used for antiabortive Chinese medicine composition and preparation thereof
Technical field
The present invention relates to a kind of be used for antiabortive, the drug regimen of treatment frequent fetal movement and habitual abortion, this medicine is formulated by Chinese crude drugs such as charred Cortex Eucommiae, Radix Dipsaci, Rhizoma Dioscoreae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Glycyrrhizaes, according to different diagnosis and treatment diseases, and this prescription or plus-minus is arranged.The invention still further relates to the preparation method of this medicine composition.Belong to the Chinese medicine technical field.
Background technology
Habitual abortion, i.e. modern medicine it " habitual abortion ".After being meant fetal abortion or abortion, becoming pregnant next time and still weigh down as scheduled, or pregnant repeatly bob repeatly, reach person more than three times.Primary disease is clinical more common, and at primary disease, doctor trained in Western medicine does not still have special effective Drug therapy, and the traditional Chinese medical science has unique advantage to the treatment of this disease.
Habitual abortion is mainly indulged in sensual pleasures and is damaged kidney qi because of congenital defect, excess of sexual intercourse, pregnant back, and tire is become homeless and is; Or plain bromhidrosis insufficiency of blood, the serious disease prolonged illness consumption gas of losing blood, tire is become homeless foster; Or plain body interior-heat caused by deficiency of YIN, not solid grade of collaterals of the uterus causes.Common pattern of syndrome has: 1. kidney qi deficiency habitual abortion.Pregnantly repeatly fall repeatly, soreness of the waist and knees, vertigo and tinnitus, spiritlessness and weakness, face have dim speckle, frequent urination at night, light red tongue has indentation, deep and weak pulse.Control the solid tire of suitable the kidney invigorating.2. weak type of qi and blood habitual abortion.Pregnantly repeatly fall repeatly, spiritlessness and weakness, shortness of breath and palpitation, light red tongue, thready and weak pulse without strength is controlled suitable benefiting QI and nourishing blood.3. type of YIN-deficiency and interior-heat habitual abortion.Pregnantly repeatly fall repeatly, hectically flushed cheeks, feverish sensation in the palms and soles, agitation is not peaceful, xerostomia, emaciated physique, red tongue, thready and rapid pulse.Control suitable replenishing YIN and removing heat.
This disease dominant mechanism is the impairment of chong and ren channels, and liability to abortion, or embryo's defective can not be shaped, so pregnantly repeatly fall repeatly.Common typing has kidney qi loss and QI and blood deficiency etc.
One, kidney qi loss
The natural endowment deficiency, kidney qi is not filled, or because of pregnant back intemperate sexual intercourse, fleshliness is hindered, so that kidney qi is thanks to empty, the debility of CHONG and REN meridians, tire is become homeless and is, is habitual abortion then and cause repeatly pregnant falling repeatly.
Two, QI and blood deficiency
Plain body weakness, insufficiency of vital energy and blood, or diet, overstrain impairing the spleen, QI and blood source deficiency, or serious disease prolonged illness, consumption impairment of QI blood all can cause QI and blood deficiency, dashes to appoint not enoughly, can not carry the fetal cultivation tire, is habitual abortion so make repeatly pregnant falling repeatly.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of habitual abortion, frequent fetal movement, and the preparation method of preparation.This drug regimen is made up of the component of following weight portion basically:
Charred Cortex Eucommiae 200~300 Radix Dipsacis 150~250 Rhizoma Dioscoreaes 100~200
Radix Angelicae Sinensis 75~175 Radix Rehmanniae Preparata 75~175 Radix Paeoniae Alba 50~100
Rhizoma Chuanxiong 25~75 Radix Glycyrrhizaes 25~75
The side separates: habitual abortion one card comes from caused by liver and kidney deficiency, the debility of CHONG and REN meridians.Kidney ends smart main reproductive development, and suffering from a deficiency of the kidney, then conception vessel is not solid.Liver hemostasis chong channel is the sea of blood, deficiency of liver-blood, and tire is become homeless foster.So invigorating the liver and kidney is solid appointing and dashes.Nourishing the liver blood is beneficial tire not to be had.Through saying: " the CHONG meridian being the blood pool REN meridian connecting with the uterus and pregnancy dashes wantonly two pulse-phases and grows so son can be arranged ".So we are monarch with the Cortex Eucommiae, get that it is warm in nature sweet, return Liver and kidney, have invigorating the liver and kidney, antiabortive function.Radix Dipsaci, Rhizoma Dioscoreae are minister.The bitter temperature of Radix Dipsaci is returned Liver and kidney, has invigorating the liver and kidney, the effectiveness of bone and muscle strengthening arresting bleeding and miscarriage prevention.Rhizoma Dioscoreae property is sweet flat, goes into the effect that the spleen kidney has tonifying the kidney to consolidate the essence.Three medicines are harmonious, and the efficacy of a drug is abundant, and at main symptom, its power is strong especially.Adjuvant drug reaches based on SIWU TANG (Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Paeoniae Alba, Rhizoma Chuanxiong), and this treating blood disorders originally.Prevent miscarriage and to manage its blood, the prosperous then beneficial feotus vitality of blood.The Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription with for make close play the antiabortive effect of reinforcing the kidney altogether.
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1, heat in blood person adds Radix Scutellariae 25~75 weight portions
2, fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 25~75 weight portions
3, the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 25~75 weight portion of Fructus Amomi
4, damaging fetus hematochezia person adds Colla Corii Asini 25~75 weight portions, charred Folium Artemisiae Argyi 50~100 weight portions, charred Radix Sanguisorbae 50~100 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 50~100 weight portions, charred Petiolus Trachycarpi 50~100 weight portions, Herba Schizonepetae 50~100 weight portions.
The disease of can dispelling the Rhizoma Atractylodis Macrocephalae wets.Radix Scutellariae is clearing away heat from blood then.Fructus Amomi energy activating QI to alleviate the depression also is an adjuvant drug.
This drug regimen preferably is made up of the component of following weight portion:
Charred Cortex Eucommiae 220~280 Radix Dipsacis 170~230 Rhizoma Dioscoreaes 120~180
Radix Angelicae Sinensis 80~160 Radix Rehmanniae Preparata 80~160 Radix Paeoniae Alba 60~90
Rhizoma Chuanxiong 35~65 Radix Glycyrrhizaes 35~65
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1, heat in blood person adds Radix Scutellariae 35~65 weight portions
2, fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 35~65 weight portions
3, the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 35~65 weight portion of Fructus Amomi
4, damaging fetus hematochezia person adds Colla Corii Asini 35~65 weight portions, charred Folium Artemisiae Argyi 60~90 weight portions, charred Radix Sanguisorbae 60~90 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 60~90 weight portions, charred Petiolus Trachycarpi 60~90 weight portions, Herba Schizonepetae 60~90 weight portions.
This drug regimen preferably is made up of the component of following weight portion:
Charred Cortex Eucommiae 250 Radix Dipsacis 200 Rhizoma Dioscoreaes 150
Radix Angelicae Sinensis 125 Radix Rehmanniae Preparata 125 Radix Paeoniae Alba 75
Rhizoma Chuanxiong 50 Radix Glycyrrhizaes 50
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1, heat in blood person adds Radix Scutellariae 50 weight portions
2, fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 50 weight portions
3, the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 50 weight portion of Fructus Amomi
4, damaging fetus hematochezia person adds Colla Corii Asini 50 weight portions, charred Folium Artemisiae Argyi 75 weight portions, charred Radix Sanguisorbae 75 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 75 weight portions, charred Petiolus Trachycarpi 75 weight portions, Herba Schizonepetae 75 weight portions.
Instructions of taking:
Habitual abortion one disease easily betides gestation the 3rd, five, July, therefore must take medicine in advance, to protect it admittedly.Promptly; Begin in two first quarter moons of gestation, took medicine continuously one month, end to three first quarter moons, had a rest one month.Began to take medicine one month in four first quarter moons again, end to five first quarter moons.Had a rest one month.Begin in six first quarter moons again, took medicine one month, end to seven first quarter moons.It is withdrawal.As not miscarrying in gestation the 3rd, five, July, can protect ordinary production on schedule.
Chinese crude drug of the present invention is the kind that Chinese Pharmacopoeia records, and be achieved through the following technical solutions:
Medicinal materials in part by weight described in the prescription is ground into fine powder, makes pill, capsule, oral formulations such as powder by the galenic pharmacy method.
Do not add any adjuvant in the Chinese medicinal composition preparation of the present invention.
Experimental example 1This prescription is prepared into pill
Take by weighing clean medical material by prescription and weight portion, be ground into fine powder with pulverizer, mistake 80~100 eye mesh screens, fine powder stirs with purified water, makes ball and sticks together, and last pellet processing machine is made the watered pill of suitable size.After the packing promptly.
Experimental example 2This prescription is prepared into powder
Take by weighing clean medical material by prescription and weight portion, be ground into fine powder, cross 80~100 eye mesh screens, the fine powder pack with pulverizer.After the packing promptly.
Experimental example 3This prescription is prepared into capsule
Take by weighing clean medical material by prescription and weight portion, be ground into fine powder with pulverizer, cross 80~100 eye mesh screens, fine powder is encapsulated by specification.After the packing promptly.
Experimental example 4The research of this prescription clinical treatment
For summing up we's clinical therapeutic efficacy, the nearly hundred routine patients that treat have been carried out the clinical observation summary, effective percentage reaches 94%.Numerical example is arranged, and hematochezia two days is surplus, adds hemorrhage with this side, and promising result is also received in hemostasis and tire is also pacified.One example being arranged for middle incurable disease, is retention of dead fetus and miscarry two tires of having miscarried without reason after promptly becoming pregnant.Control it with this side, also receive produce effects, give birth to healthy fetus.
The specific embodiment
Embodiment 1The preparation of pill
Take by weighing the clean medical material of prescription according to following prescription:
Charred Cortex Eucommiae 250 Radix Dipsacis 200 Rhizoma Dioscoreaes 150
Radix Angelicae Sinensis 125 Radix Rehmanniae Preparata 125 Radix Paeoniae Alba 75
Rhizoma Chuanxiong 50 Radix Glycyrrhizaes 50
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1, heat in blood person adds Radix Scutellariae 50 weight portions
2, fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 50 weight portions
3, the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 50 weight portion of Fructus Amomi
4, damaging fetus hematochezia person adds Colla Corii Asini 50 weight portions, charred Folium Artemisiae Argyi 75 weight portions, charred Radix Sanguisorbae 75 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 75 weight portions, charred Petiolus Trachycarpi 75 weight portions, Herba Schizonepetae 75 weight portions.
Behind above-mentioned medical material uniform mixing, be ground into fine powder with pulverizer, cross 80~100 eye mesh screens, fine powder stirs with purified water, makes ball and sticks together, and last pellet processing machine is made the watered pill that suitably per 10 balls weigh 2g.After the packing promptly.
Embodiment 2The preparation of powder
Take by weighing the clean medical material of prescription according to following prescription:
Charred Cortex Eucommiae 250 Radix Dipsacis 200 Rhizoma Dioscoreaes 150
Radix Angelicae Sinensis 125 Radix Rehmanniae Preparata 125 Radix Paeoniae Alba 75
Rhizoma Chuanxiong 50 Radix Glycyrrhizaes 50
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1, heat in blood person adds Radix Scutellariae 50 weight portions
2, fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 50 weight portions
3, the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 50 weight portion of Fructus Amomi
4, damaging fetus hematochezia person adds Colla Corii Asini 50 weight portions, charred Folium Artemisiae Argyi 75 weight portions, charred Radix Sanguisorbae 75 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 75 weight portions, charred Petiolus Trachycarpi 75 weight portions, Herba Schizonepetae 75 weight portions.
Behind above-mentioned medical material uniform mixing, be ground into fine powder with pulverizer, cross 80~100 eye mesh screens, fine powder is by the specification pack of every bag of 6g.After the packing promptly.
Embodiment 3The preparation of capsule
Take by weighing the clean medical material of prescription according to following prescription:
Charred Cortex Eucommiae 250 Radix Dipsacis 200 Rhizoma Dioscoreaes 150
Radix Angelicae Sinensis 125 Radix Rehmanniae Preparata 125 Radix Paeoniae Alba 75
Rhizoma Chuanxiong 50 Radix Glycyrrhizaes 50
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1, heat in blood person adds Radix Scutellariae 50 weight portions
2, fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 50 weight portions
3, the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 50 weight portion of Fructus Amomi
4, damaging fetus hematochezia person adds Colla Corii Asini 50 weight portions, charred Folium Artemisiae Argyi 75 weight portions, charred Radix Sanguisorbae 75 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 75 weight portions, charred Petiolus Trachycarpi 75 weight portions, Herba Schizonepetae 75 weight portions.
Behind above-mentioned medical material uniform mixing, be ground into fine powder with pulverizer, cross 80~100 eye mesh screens, fine powder is inserted capsule by the specification of every dress 2g.After the packing promptly.

Claims (4)

1, a kind of have an antiabortive effect, is used for the treatment of the Chinese medicine composition of habitual abortion, frequent fetal movement, it is characterized in that being made up of following components by part by weight:
Charred Cortex Eucommiae 200~300 Radix Dipsacis 150~250 Rhizoma Dioscoreaes 100~200
Radix Angelicae Sinensis 75~175 Radix Rehmanniae Preparata 75~175 Radix Paeoniae Alba 50~100
Rhizoma Chuanxiong 25~75 Radix Glycyrrhizaes 25~75
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1. heat in blood person adds Radix Scutellariae 25~75 weight portions
2. fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 25~75 weight portions
3. the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 25~75 weight portion of Fructus Amomi
4. damaging fetus hematochezia person adds Colla Corii Asini 25~75 weight portions, charred Folium Artemisiae Argyi 50~100 weight portions, charred Radix Sanguisorbae 50~100 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 50~100 weight portions, charred Petiolus Trachycarpi 50~100 weight portions, Herba Schizonepetae 50~100 weight portions.
2, Chinese medicine composition according to claim 1, wherein the weight portion of each component is preferred:
Charred Cortex Eucommiae 220~280 Radix Dipsacis 170~230 Rhizoma Dioscoreaes 120~180
Radix Angelicae Sinensis 80~160 Radix Rehmanniae Preparata 80~160 Radix Paeoniae Alba 60~90
Rhizoma Chuanxiong 35~65 Radix Glycyrrhizaes 35~65
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1. heat in blood person adds Radix Scutellariae 35~65 weight portions
2. fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 35~65 weight portions
3. the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 35~65 weight portion of Fructus Amomi
4. damaging fetus hematochezia person adds Colla Corii Asini 35~65 weight portions, charred Folium Artemisiae Argyi 60~90 weight portions, charred Radix Sanguisorbae 60~90 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 60~90 weight portions, charred Petiolus Trachycarpi 60~90 weight portions, Herba Schizonepetae 60~90 weight portions.
3, Chinese medicine composition according to claim 1, preferably form by the component of following weight portion:
Charred Cortex Eucommiae 250 Radix Dipsacis 200 Rhizoma Dioscoreaes 150
Radix Angelicae Sinensis 125 Radix Rehmanniae Preparata 125 Radix Paeoniae Alba 75
Rhizoma Chuanxiong 50 Radix Glycyrrhizaes 50
According to the card Hou Butong of habitual abortion disease, this compositions can suitably be added and subtracted:
1. heat in blood person adds Radix Scutellariae 50 weight portions
2. fat have the damp-phlegm person add the Rhizoma Atractylodis Macrocephalae 50 weight portions
3. the depression of QI person adds Caulis Perillae, Pericarpium Arecae, Pericarpium Citri Reticulatae, each 50 weight portion of Fructus Amomi
4. damaging fetus hematochezia person adds Colla Corii Asini 50 weight portions, charred Folium Artemisiae Argyi 75 weight portions, charred Radix Sanguisorbae 75 weight portions, Cacumen Platycladi (Cacumen Biotae) charcoal 75 weight portions, charred Petiolus Trachycarpi 75 weight portions, Herba Schizonepetae 75 weight portions.
4, Chinese medicine composition according to claim 1 can be made into solid orally ingestibles such as pill, powder, capsule according to practice of pharmacy.
CNA2007100561665A 2007-10-15 2007-10-15 Method for preparing Chinese medicinal composition for anti-abortion and formulation thereof Pending CN101411801A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912551A (en) * 2010-08-02 2010-12-15 吴清玲 Miscarriage-prevention Chinese medicinal composition
CN102106984B (en) * 2009-12-23 2012-07-25 廖益伦 Medicinal composition for treating pernicious vomiting and fetal irritability
CN103039704A (en) * 2012-12-18 2013-04-17 广州优锐生物科技有限公司 Probiotics Chinese herbal medicine composite biological preparation as well as preparation method and application thereof
CN103536697A (en) * 2013-11-03 2014-01-29 祁阳县高德种养专业合作社 Nutrient solution capable of increasing fertilization rate of artificial poultry insemination

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102106984B (en) * 2009-12-23 2012-07-25 廖益伦 Medicinal composition for treating pernicious vomiting and fetal irritability
CN101912551A (en) * 2010-08-02 2010-12-15 吴清玲 Miscarriage-prevention Chinese medicinal composition
CN103039704A (en) * 2012-12-18 2013-04-17 广州优锐生物科技有限公司 Probiotics Chinese herbal medicine composite biological preparation as well as preparation method and application thereof
CN103039704B (en) * 2012-12-18 2015-01-14 广州优锐生物科技有限公司 Probiotics Chinese herbal medicine composite biological preparation as well as preparation method and application thereof
CN103536697A (en) * 2013-11-03 2014-01-29 祁阳县高德种养专业合作社 Nutrient solution capable of increasing fertilization rate of artificial poultry insemination
CN103536697B (en) * 2013-11-03 2015-02-25 祁阳县高德种养专业合作社 Nutrient solution capable of increasing fertilization rate of artificial poultry insemination

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Open date: 20090422