CN1593534A - Blood sugar lowering capsules and preparation thereof - Google Patents
Blood sugar lowering capsules and preparation thereof Download PDFInfo
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- CN1593534A CN1593534A CN 200410023400 CN200410023400A CN1593534A CN 1593534 A CN1593534 A CN 1593534A CN 200410023400 CN200410023400 CN 200410023400 CN 200410023400 A CN200410023400 A CN 200410023400A CN 1593534 A CN1593534 A CN 1593534A
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- rhizoma dioscoreae
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- ginseng rubra
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Abstract
The invention discloses a traditional Chinese medicament for treating diabetes, whose main compositions (by weight ratio) include percik 45-56%, Siberian solomonseal rhizome 10-20%, Stevia rebaudiana 2-3%, mulberry, rhizoma dioscoreae, root of Chinese trichosannthes each 8-12%, red ginseng 2-4%.
Description
Technical field:
The present invention relates to a kind of Chinese patent medicine capsule and preparation technology's method thereof, relate in particular to XIAOKE JIANGTANG JIAONANG and preparation method thereof.
Background technology:
Capsule is a kind of pharmaceutical dosage form commonly used, according to the relevant laws and regulations of China's drug control, changes dosage form and manages as new drug research.The original dosage form of this product is a tablet, has listed Drug Standard of Ministry of Public Health of the Peoples Republic of China in.
The technology features of former tablet is that part pulverizing medicinal materials in the prescription is standby, and mix with above-mentioned medical material fine powder all the other medicinal material extract, precipitate with ethanol, concentrated back, granulation, drying, and tabletting, promptly.
There is difficult disintegrate in existing blood-sugar reducing tablets, and onset is slow, and medicine stability is poor, the drawback that quality standard control is not tight.
Summary of the invention:
The purpose of this invention is to provide the rapid disintegrate onset of a kind of energy.Be used for the treatment of Chinese patent medicine preparation of diabetes and preparation method thereof, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of XIAOKE JIANGTANG JIAONANG, is a kind of Chinese patent medicine for the treatment of diabetes, it is characterized in that it is is the capsule of Saccharum sinensis Roxb, Rhizoma Polygonati (system), Folium Stevlae Rebaudianae, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis, Radix Ginseng Rubra by main constituent.
The preparation method of XIAOKE JIANGTANG JIAONANG is:
(1) getting main medicine constituent and percentage by weight thereof is:
Saccharum sinensis Roxb 45～55%, Rhizoma Polygonati (system) 10～20%, Folium Stevlae Rebaudianae 2～3%, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis each 8～12%, Radix Ginseng Rubra 2～4%;
(2) in the said medicine, get Folium Stevlae Rebaudianae, day SHANFEN, Radix Ginseng Rubra, Rhizoma Dioscoreae powder and be broken into fine powder, cross 80～160 mesh sieves; The best was 100 mesh sieves, and was standby;
(3) three flavors such as all the other Saccharum sinensis Roxb in the said medicine decoct with water 2～3 times, and amount of water is 6～14 times of amounts of medication amount for the first time, and second and third time amount of water is 4～12 times of amounts of medication amount, each 1～3 hour; Best for decocting with water 2 times, the 1st time 2 hours, the 2nd time 1 hour; Medicinal liquid merges, and filters;
(4) above-mentioned (3) gained medicinal liquid being concentrated into relative density is 1.10～1.40 (60～80 ℃), adds ethanol and makes that to contain alcohol amount be 50～70%, leaves standstill 24～48 hours; Best for being 60% for containing the alcohol amount, left standstill 24 hours;
(5) supernatant concentration to the relative density with gained behind above-mentioned (4) precipitate with ethanol is 1.20～1.35 (70 ℃); The best is the clear paste of 1.26～1.28 (70 ℃) for relative density;
(6) with fine powder of above-mentioned (2) gained and the clear paste mixing of (5) gained, granulate, drying, fill becomes capsule, promptly.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of XIAOKE JIANGTANG JIAONANG, its main constituent is: Saccharum sinensis Roxb, Rhizoma Polygonati (system), Folium Stevlae Rebaudianae, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis, Radix Ginseng Rubra.
A kind of optimum implementation of XIAOKE JIANGTANG JIAONANG preparation method:
(1) get main constituent and optimum weight percentage ratio is: Saccharum sinensis Roxb 49.16%, Rhizoma Polygonati (system) 15.97%, Folium Stevlae Rebaudianae 2.46%, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis each 9.82%, Radix Ginseng Rubra 2.95%;
(2) in the said medicine, Folium Stevlae Rebaudianae, day SHANFEN, Radix Ginseng Rubra, Rhizoma Dioscoreae powder are broken into fine powder, sieving for standby, three flavor extracting in waters such as all the other Saccharum sinensis Roxb 2 times, the 1st time 2 hours, the 2nd time 1 hour, merge extractive liquid, filters, and filtrate concentrates, add ethanol and make that to contain alcohol amount be 60%, left standstill 24 hours, get the clear paste that supernatant concentration to relative density is 1.26～1.28 (70 ℃), add above-mentioned fine powder mixing, granulate drying, fill becomes 1000 capsules, and packing promptly.
Advantage of the present invention is:
Capsule for lowering blood sugar and preventing thirst is easy to carry, and disintegration is fast, and is rapid-action, and medicine stability is good, is conducive to storage and improves treatment Effect can satisfy the treatment needs better.
Claims (3)
1, a kind of XIAOKE JIANGTANG JIAONANG is a kind of Chinese patent medicine for the treatment of diabetes, it is characterized in that it is that main constituent is the capsule of Saccharum sinensis Roxb, Rhizoma Polygonati (system), Folium Stevlae Rebaudianae, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis, Radix Ginseng Rubra.
2, a kind of preparation method of XIAOKE JIANGTANG JIAONANG is characterized in that:
(1) getting main medicine constituent and percentage by weight thereof is:
Saccharum sinensis Roxb 45～55%, Rhizoma Polygonati (system) 10～20%, Folium Stevlae Rebaudianae 2～3%, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis each 8～12%, Radix Ginseng Rubra 2～4%;
(2) in the said medicine, get Folium Stevlae Rebaudianae, day SHANFEN, Radix Ginseng Rubra, Rhizoma Dioscoreae powder and be broken into fine powder, cross 80～160 mesh sieves; The best was 100 mesh sieves, and was standby;
(3) three flavors such as all the other Saccharum sinensis Roxb in the said medicine decoct with water and extract 2～3 times, and amount of water is 6～14 times of amounts of medication amount for the first time, and second and third time amount of water is 4～12 times of amounts of medication amount, each 1～3 hour; Best for decocting with water extraction 2 times, the 1st time 2 hours, the 2nd time 1 hour; Medicinal liquid merges, and filters;
(4) above-mentioned (3) gained medicinal liquid being concentrated into relative density is 1.10～1.40 (60～80 ℃), adds ethanol and makes that to contain alcohol amount be 50～70%, leaves standstill 24～48 hours; Best is 60% for containing the alcohol amount, leaves standstill 24 hours;
(5) supernatant concentration to the relative density of getting behind above-mentioned (4) gained precipitate with ethanol is 1.20～1.35 (70 ℃), and best relative density is the clear paste of 1.26～1.28 (70 ℃);
(6) with the clear paste mixing of above-mentioned (2) gained fine powder, granulate with (5) gained, drying, fill becomes capsule, promptly.
3, the preparation method of XIAOKE JIANGTANG JIAONANG according to claim 2 is characterized in that the optimum weight percentage ratio of its main constituent is:
Saccharum sinensis Roxb 49.16%, Rhizoma Polygonati (system) 15.97%, Folium Stevlae Rebaudianae 2.46%, Fructus Mori, Rhizoma Dioscoreae, Radix Trichosanthis each 9.82%, Radix Ginseng Rubra 2.95%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410023400 CN1593534A (en) | 2004-07-06 | 2004-07-06 | Blood sugar lowering capsules and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410023400 CN1593534A (en) | 2004-07-06 | 2004-07-06 | Blood sugar lowering capsules and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1593534A true CN1593534A (en) | 2005-03-16 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410023400 Pending CN1593534A (en) | 2004-07-06 | 2004-07-06 | Blood sugar lowering capsules and preparation thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN1593534A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237067A (en) * | 2016-08-30 | 2016-12-21 | 山东百维药业有限公司 | A kind of XIAOKE JIANGTANG JIAONANG and preparation method thereof |
| CN108743769A (en) * | 2018-05-10 | 2018-11-06 | 湖南康尔佳制药股份有限公司 | A kind of capsule for lowering blood sugar and preventing thirst and preparation method thereof |
-
2004
- 2004-07-06 CN CN 200410023400 patent/CN1593534A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237067A (en) * | 2016-08-30 | 2016-12-21 | 山东百维药业有限公司 | A kind of XIAOKE JIANGTANG JIAONANG and preparation method thereof |
| CN108743769A (en) * | 2018-05-10 | 2018-11-06 | 湖南康尔佳制药股份有限公司 | A kind of capsule for lowering blood sugar and preventing thirst and preparation method thereof |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |