CN1583055A - Chinese medicinal capsules for disinfecting and relieving toxicity and their preparation - Google Patents
Chinese medicinal capsules for disinfecting and relieving toxicity and their preparation Download PDFInfo
- Publication number
- CN1583055A CN1583055A CNA2004100233031A CN200410023303A CN1583055A CN 1583055 A CN1583055 A CN 1583055A CN A2004100233031 A CNA2004100233031 A CN A2004100233031A CN 200410023303 A CN200410023303 A CN 200410023303A CN 1583055 A CN1583055 A CN 1583055A
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- China
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- capsule
- adjuvant
- preparation
- herba andrographis
- radix wikstroemae
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Abstract
A Chinese medicine in the form of capsule for relieving inflammation and detoxication is prepared from green chiretta, Indian stringbush and auxiliary through extracting from green chiretta in alcohol twice, collecting liquid extract, laying aside, filtering, recovering alcohol, concentrating to obtain extract, decocting Indian stringbush, filteing, mixing decoction with said extract, adding auxiliary, granulating, drying, and loading in capsules.
Description
Technical field:
The present invention relates to a kind of Chinese medicinal capsule agent and process for making thereof, relate in particular to a kind of antiinflammatory toxin resolving capsule and preparation method thereof.
Background technology:
Capsule, changes dosage form and manages as new drug research according to the relevant laws and regulations of China's drug control as a kind of pharmaceutical dosage form.The original conventional tablet dosage form of this preparation, and all list the national drug ministry standard in.
The technology features that the eliminating inflammation and expelling toxin tablet is arranged earlier is with after the extraction of prescription Chinese crude drug, being condensed into thick paste, adds suitable adjuvant, granulates dry back tabletting, sugar coating promptly.
Conventional tablet has prolonged disintegration, influences shortcomings such as medicine plays a role rapidly.
Summary of the invention:
The purpose of this invention is to provide Chinese medicinal capsule of a kind of eliminating inflammation and expelling toxin and preparation method thereof, overcome the above-mentioned defective of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of Chinese medicine preparation of eliminating inflammation and expelling toxin, it is characterized in that it is that main component is the capsule of Herba Andrographis, Radix Wikstroemae.
The preparation method of this capsule is:
(1) getting percentage by weight is 30-70% Herba Andrographis, 30-70% Radix Wikstroemae;
(2) Herba Andrographis is ground into coarse powder, adds 85% ethanol hot dipping secondary, each 2 hours (or reflux, extract,, each 1-2 hour), merge extractive liquid, leaves standstill, and filtrate recycling ethanol is condensed into relative density and is the clear paste of 1.20-1.30 (55-60 ℃) to there not being the alcohol flavor, and is standby;
(3) Radix Wikstroemae decocts with water secondary, and each 2-5 hour, collecting decoction filtered filtrate for later use;
(4) (2) and (3) are merged, be condensed into thick paste, or be dried to dried cream, pulverize, standby;
(5) in (4) gained thick paste or dried cream powder, add an amount of adjuvant mix homogeneously, granulate drying;
The granulation adjuvant is one or more a various combination in lactose, calcium sulfate, sucrose, microcrystalline Cellulose, soluble starch, pregelatinized Starch, carboxymethyl starch sodium, xylitol, starch, dextrin, sodium carboxymethyl cellulose, the low-substituted hydroxypropyl cellulose;
(6) granule by (5) gained adds an amount of adjuvant mix homogeneously, encapsulating capsule; Or do not add the direct encapsulating capsule of adjuvant;
To add adjuvant be one or more various combination in Pulvis Talci, magnesium stearate, the micropowder silica gel;
The specific embodiment:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of capsule of eliminating inflammation and expelling toxin is a kind of sterilization antidotal Chinese medicine preparation, and it contains main component and is: Herba Andrographis, Radix Wikstroemae.
To produce 1000 capsules is example, and its preparation method is:
(1) gets Herba Andrographis 1200g, Radix Wikstroemae 800g;
(2) Herba Andrographis is ground into coarse powder, adds 85% ethanol hot dipping secondary, each 2 hours (or reflux, extract,, each 1-2 hour), merge extractive liquid, leaves standstill, filtrate recycling ethanol is condensed into relative density and is the clear paste of 1.20-1.30 (55-60 ℃) to there not being the alcohol flavor, and is standby; Radix Wikstroemae decocts with water secondary, and each 2-5 hour, collecting decoction filtered filtrate for later use;
(3) Herba Andrographis clear paste, Radix Wikstroemae extracting solution are merged, be condensed into thick paste, be dried to dried cream, pulverize;
(4) in (3) gained dried cream powder, add an amount of adjuvant mix homogeneously, granulate drying;
Adjuvant is 10% microcrystalline Cellulose, and its percentage ratio metering radix is the total amount of dried cream powder;
(5) by adding an amount of adjuvant mix homogeneously, encapsulating capsule behind the granule granulate of (4) gained;
Adjuvant is 3% micropowder silica gel, and its percentage ratio metering radix is the total amount of dried cream powder.
Advantage of the present invention is:
This capsule is made up of medicine and filler, is easy to carry, and disintegrate rapidly, little, the taking convenience of dose help improving curative effect.
Claims (3)
1, a kind of Chinese medicinal capsule of eliminating inflammation and expelling toxin is characterized in that it is that main component is the capsule of Herba Andrographis, Radix Wikstroemae.
2, a kind of preparation method of antiinflammatory toxin resolving capsule is characterized in that:
(1) getting percentage by weight is 30-70% Herba Andrographis, 30-70% Radix Wikstroemae;
(2) Herba Andrographis is ground into coarse powder, adds 85% ethanol hot dipping secondary, each 2 hours (or reflux, extract,, each 1-2 hour), merge extractive liquid, leaves standstill, and filtrate recycling ethanol is condensed into relative density and is the clear paste of 1.20-1.30 (55-60 ℃) to there not being the alcohol flavor, and is standby;
(3) Radix Wikstroemae decocts with water secondary, and each 2-5 hour, collecting decoction filtered filtrate for later use;
(4) (2) and (3) are merged, be condensed into thick paste, or be dried to dried cream, pulverize, standby;
(5) in (4) gained thick paste or dried cream powder, add an amount of adjuvant mix homogeneously, granulate drying;
The granulation adjuvant is one or more a various combination in lactose, calcium sulfate, sucrose, microcrystalline Cellulose, soluble starch, pregelatinized Starch, carboxymethyl starch sodium, xylitol, starch, dextrin, sodium carboxymethyl cellulose, the low-substituted hydroxypropyl cellulose;
(6) granule by (5) gained adds an amount of adjuvant mix homogeneously, encapsulating capsule; Or do not add the direct encapsulating capsule of adjuvant;
To add adjuvant be one or more various combination in Pulvis Talci, magnesium stearate, the micropowder silica gel;
3, the preparation method of antiinflammatory toxin resolving capsule according to claim 2 is characterized in that the optimum weight proportioning of its main constituent is:
60% Herba Andrographis, 40% Radix Wikstroemae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100233031A CN100358554C (en) | 2004-06-16 | 2004-06-16 | Chinese medicinal capsules for disinfecting and relieving toxicity and their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100233031A CN100358554C (en) | 2004-06-16 | 2004-06-16 | Chinese medicinal capsules for disinfecting and relieving toxicity and their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1583055A true CN1583055A (en) | 2005-02-23 |
| CN100358554C CN100358554C (en) | 2008-01-02 |
Family
ID=34600774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100233031A Expired - Fee Related CN100358554C (en) | 2004-06-16 | 2004-06-16 | Chinese medicinal capsules for disinfecting and relieving toxicity and their preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100358554C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107929635A (en) * | 2017-12-29 | 2018-04-20 | 广西万德药业有限公司 | Treat Herbal compound capsule of chronic nephritis and preparation method thereof |
| CN113041308A (en) * | 2021-05-19 | 2021-06-29 | 一力制药(罗定)有限公司 | A Chinese medicinal composition with anti-inflammatory and toxic materials clearing away effects, and its preparation method |
| CN117159630A (en) * | 2023-09-04 | 2023-12-05 | 一力制药(罗定)有限公司 | Preparation method of Chuanwang anti-inflammatory capsule |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102755450B (en) * | 2012-07-19 | 2015-04-29 | 江西青春康源制药有限公司 | Preparation method of anti-inflammation detoxifying traditional Chinese medicine composition |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368127A (en) * | 2001-02-02 | 2002-09-11 | 杨孟君 | Nano medicine 'Liandanxiaoyan' and its preparing process |
| CN1215867C (en) * | 2003-03-14 | 2005-08-24 | 周纯喜 | Broad-spectrum anti-inflammatory antiviral Chinese medicine preparation and preparing method thereof |
-
2004
- 2004-06-16 CN CNB2004100233031A patent/CN100358554C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107929635A (en) * | 2017-12-29 | 2018-04-20 | 广西万德药业有限公司 | Treat Herbal compound capsule of chronic nephritis and preparation method thereof |
| CN113041308A (en) * | 2021-05-19 | 2021-06-29 | 一力制药(罗定)有限公司 | A Chinese medicinal composition with anti-inflammatory and toxic materials clearing away effects, and its preparation method |
| CN117159630A (en) * | 2023-09-04 | 2023-12-05 | 一力制药(罗定)有限公司 | Preparation method of Chuanwang anti-inflammatory capsule |
| CN117159630B (en) * | 2023-09-04 | 2024-05-17 | 一力制药(罗定)有限公司 | Preparation method of Chuanwang anti-inflammatory capsule |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100358554C (en) | 2008-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: LI YEHUA Free format text: FORMER OWNER: TAN SIYU Effective date: 20071214 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20071214 Address after: Room 3, building 402, hung Hai garden, 123 slope road, Changsha, Tongzi, Hunan Patentee after: Li Yehua Address before: Room 21, building 602, staff residence, Golden Village village, Changsha University of Science and Technology, Changsha, 9 Ling Lu, Hunan, China Patentee before: Qin Siyu |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080102 Termination date: 20150616 |
|
| EXPY | Termination of patent right or utility model |