CN1748745A - Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method - Google Patents
Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method Download PDFInfo
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- CN1748745A CN1748745A CNA2005100316842A CN200510031684A CN1748745A CN 1748745 A CN1748745 A CN 1748745A CN A2005100316842 A CNA2005100316842 A CN A2005100316842A CN 200510031684 A CN200510031684 A CN 200510031684A CN 1748745 A CN1748745 A CN 1748745A
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Abstract
The Chinese medicine granule for tonifying blood, regulating menstruation, arresting bleeding and preventing abortion is prepared with prepared rhizome of rehmannia, Chuanxiong rhizome, moxa leaf, licorice, white peony root, angelica and donkey-hide gelatin in certain weight proportion. The preparation process of the Chinese medicine granule includes the steps of: grinding and sieving donkey-hide gelatin; extracting volatile oil with angelica, moxa leaf and Chuanxiong rhizome; decocting the dregs after volatile oil extraction, white peony root, prepared rhizome of rehmannia and licorice, filtering the decoction, and concentration to obtain extractum; mixing donkey-hide gelatin, the extractum and supplementary material, pelletizing, drying, spraying volatile oil and sealing for 2 hr; and packing.
Description
Technical field:
The present invention relates to a kind of Chinese medicine granules and preparation technology's method thereof, relate in particular to Chinese medicine granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and preparation method thereof.
Background technology:
Granule, changes dosage form and manages as new drug research according to the relevant laws and regulations of China's drug control as a kind of pharmaceutical dosage form.The original dosage form of this product is a mixture, has listed the national drug standards in.
The technology features of existing mixture is after the part medical material is carried volatile oil, and medicinal residues and other recipe quantity medical materials decoct, and decocting liquid is condensed in right amount; The part pulverizing medicinal materials, dissolve back and above-mentioned medicinal liquid and volatile oil mix homogeneously after, add suitable adjuvant, adjust volume after, filter, fill, sterilization is promptly.
There is shortcomings such as carrying, use inconvenience in the herb mixture of existing tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention.
Summary of the invention:
The purpose of this invention is to provide use, a kind of tonifying blood and regulating menstruation easy to carry, Chinese medicine preparation of arresting bleeding and miscarriage prevention and preparation method thereof, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is the Chinese medicine granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention, it is characterized in that it is that main component is the granular preparation of Radix Rehmanniae Preparata, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Folium Artemisiae Argyi, Radix Angelicae Sinensis, Radix Glycyrrhizae, Colla Corii Asini.
Be mainly used in severe loss of blood, shallow complexion, menoxenia, cold and pain in the lower abdomen, vaginal bleeding during pregnancy fetal movement, anal fistula hematochezia.
The preparation method of the Chinese medicine granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention is:
(1) medicine constituent and percentage by weight consumption thereof are got the raw materials ready as follows:
Radix Rehmanniae Preparata 15～30%, Rhizoma Chuanxiong, Folium Artemisiae Argyi, Radix Glycyrrhizae each 5～15%, the Radix Paeoniae Alba 15～25%, Radix Angelicae Sinensis, Colla Corii Asini each 10～20%;
(2) get the Colla Corii Asini in (1) spice, be ground into fine powder, cross 100 mesh sieves, standby;
(3) Radix Angelicae Sinensis, Folium Artemisiae Argyi, the Rhizoma Chuanxiong got in (1) spice extract volatile oil, and it is standby to collect volatile oil; Medicinal residues and water liquid are standby;
(4) get medicinal residues of (3) gained and the Radix Paeoniae Alba, Radix Rehmanniae Preparata, the Radix Glycyrrhizae in water liquid medicinal residues and aqueous solution and (1) spice and decoct with water secondary, 3 hours for the first time, 2 hours for the second time, collecting decoction, left standstill 18～24 hours, get supernatant and filter, filtrate decompression is concentrated into the clear paste that relative density is 1.30 (60 ℃ of surveys), and is standby; Or after clear paste is dried to dried cream, be ground into fine powder, and cross 100 mesh sieves, standby;
(5) after getting (2) gained fine powder and an amount of adjuvant mix homogeneously, add (4) gained clear paste or dried cream powder, mixing adds suitable adhesive system soft material, granulation, drying, and behind the granulate, granule is standby;
The granulation adjuvant is: one or more various combination in lactose, sucrose, dextrin, xylitol, starch, soluble starch, the micropowder silica gel;
(6) get (3) gained volatile oil, spray in (5) gained granule, mixing, airtight placement 2 hours, packing, promptly.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
The Chinese medicine granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention, it is that main component is the granular preparation of Radix Rehmanniae Preparata, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Folium Artemisiae Argyi, Radix Angelicae Sinensis, Radix Glycyrrhizae, Colla Corii Asini.
Chinese medicine granules with preparation 1000g tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention is an example, and preparation method is:
(1) consumption of medicine constituent is as follows:
Radix Rehmanniae Preparata 173g, Rhizoma Chuanxiong 69g, Radix Paeoniae Alba 139g, Folium Artemisiae Argyi 69g, Radix Angelicae Sinensis 104g, Radix Glycyrrhizae 69g, Colla Corii Asini 104g;
(2) get the Colla Corii Asini in (1) spice, be ground into fine powder, cross 100 mesh sieves, standby;
(3) Radix Angelicae Sinensis, Folium Artemisiae Argyi, the Rhizoma Chuanxiong got in (1) spice extract volatile oil, and it is standby to collect volatile oil; Medicinal residues and water liquid are standby;
(4) get medicinal residues of (3) gained and the Radix Paeoniae Alba, Radix Rehmanniae Preparata, the Radix Glycyrrhizae in water liquid medicinal residues and aqueous solution and (1) spice and decoct with water secondary, 3 hours for the first time, 2 hours for the second time, collecting decoction, left standstill 18～24 hours, get supernatant and filter, filtrate decompression is concentrated into the clear paste that relative density is 1.30 (60 ℃ of surveys), and is standby;
(5) after getting (2) gained fine powder and sucrose 500g, dextrin 250g mix homogeneously, add (4) gained clear paste mixing, add 85% suitable ethanol system soft material, granulation, drying, behind the granulate, granule is standby;
(6) get (3) gained volatile oil, spray in (5) gained granule, mixing, airtight placement 2 hours, packing, promptly.
Advantage of the present invention is:
The Chinese herbal granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention is made up of medicine and excipients, and it is with solid-state form Deposit, be conducive to carry with easy to use.
Claims (3)
1, the Chinese medicine granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention is characterized in that it is that main constituent is the granular preparation of Radix Rehmanniae Preparata, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Folium Artemisiae Argyi, Radix Angelicae Sinensis, Radix Glycyrrhizae, Colla Corii Asini.
2, the preparation method of the Chinese medicine granules of a kind of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention is characterized in that:
(1) medicine constituent and percentage by weight consumption thereof are got the raw materials ready as follows:
Radix Rehmanniae Preparata 15～30%, Rhizoma Chuanxiong, Folium Artemisiae Argyi, Radix Glycyrrhizae each 5～15%, the Radix Paeoniae Alba 15～25%, Radix Angelicae Sinensis, Colla Corii Asini each 10～20%;
(2) get the Colla Corii Asini in (1) spice, be ground into fine powder, cross 100 mesh sieves, standby;
(3) Radix Angelicae Sinensis, Folium Artemisiae Argyi, the Rhizoma Chuanxiong got in (1) spice extract volatile oil, and it is standby to collect volatile oil; Medicinal residues and water liquid are standby;
(4) get medicinal residues of (3) gained and the Radix Paeoniae Alba, Radix Rehmanniae Preparata, the Radix Glycyrrhizae in water liquid medicinal residues and aqueous solution and (1) spice and decoct with water secondary, 3 hours for the first time, 2 hours for the second time, collecting decoction, left standstill 18～24 hours, get supernatant and filter, filtrate decompression is concentrated into the clear paste that relative density is 1.30 (60 ℃ of surveys), and is standby; Or after clear paste is dried to dried cream, be ground into fine powder, and cross 100 mesh sieves, standby;
(5) after getting (2) gained fine powder and an amount of adjuvant mix homogeneously, add (4) gained clear paste or dried cream powder, mixing adds suitable adhesive system soft material, granulation, drying, and behind the granulate, granule is standby;
The granulation adjuvant is: one or more various combination in lactose, sucrose, dextrin, xylitol, starch, soluble starch, the micropowder silica gel;
(6) get (3) gained volatile oil, spray in (5) gained granule, mixing, airtight placement 2 hours, packing, promptly.
3, the preparation method of the Chinese medicine granules of a kind of tonifying blood and regulating menstruation according to claim 2, arresting bleeding and miscarriage prevention is characterized in that its main constituent optimum weight percentage ratio is:
Radix Rehmanniae Preparata 23.8%, Rhizoma Chuanxiong, Folium Artemisiae Argyi, Radix Glycyrrhizae each 9.5%, the Radix Paeoniae Alba 19.1%, Radix Angelicae Sinensis, Colla Corii Asini each 14.3%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005100316842A CN1748745A (en) | 2005-06-10 | 2005-06-10 | Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method |
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| CNA2005100316842A CN1748745A (en) | 2005-06-10 | 2005-06-10 | Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method |
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| CN1748745A true CN1748745A (en) | 2006-03-22 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526322A (en) * | 2010-12-15 | 2012-07-04 | 苏州知微堂生物科技有限公司 | Preparation technology and production method of novel integrated Jiaoai decoction dosage form |
| CN102552517A (en) * | 2011-12-28 | 2012-07-11 | 武汉哈瑞医药有限公司 | Gynecological sugar-free gynaecopathia treating particle and preparation method thereof |
| CN103751747A (en) * | 2014-01-16 | 2014-04-30 | 曲洪翠 | Traditional Chinese medicine for treating vaginal bleeding after medical abortion |
| CN104800386A (en) * | 2015-04-17 | 2015-07-29 | 成都市飞龙水处理技术研究所青白江第一分所 | Orally-taken medicine for treating threatened abortion and preparation method of orally-taken medicine |
| CN104997922A (en) * | 2015-08-05 | 2015-10-28 | 南京中医药大学 | Refined traditional Chinese medicine composition extract with hemostasis and miscarriage prevention effect and application thereof |
| CN108175802A (en) * | 2018-01-30 | 2018-06-19 | 重庆芸峰药业有限公司 | A kind of FUKANGBAO KOUFUYE and preparation method thereof |
| CN108272981A (en) * | 2018-03-14 | 2018-07-13 | 江西地康药业有限公司 | Fukangbao koufuye |
| CN115607515A (en) * | 2022-11-04 | 2023-01-17 | 杭州市中医院 | Preparation process of spleen-tonifying miscarriage-preventing granules |
-
2005
- 2005-06-10 CN CNA2005100316842A patent/CN1748745A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526322A (en) * | 2010-12-15 | 2012-07-04 | 苏州知微堂生物科技有限公司 | Preparation technology and production method of novel integrated Jiaoai decoction dosage form |
| CN102552517A (en) * | 2011-12-28 | 2012-07-11 | 武汉哈瑞医药有限公司 | Gynecological sugar-free gynaecopathia treating particle and preparation method thereof |
| CN103751747A (en) * | 2014-01-16 | 2014-04-30 | 曲洪翠 | Traditional Chinese medicine for treating vaginal bleeding after medical abortion |
| CN104800386A (en) * | 2015-04-17 | 2015-07-29 | 成都市飞龙水处理技术研究所青白江第一分所 | Orally-taken medicine for treating threatened abortion and preparation method of orally-taken medicine |
| CN104997922A (en) * | 2015-08-05 | 2015-10-28 | 南京中医药大学 | Refined traditional Chinese medicine composition extract with hemostasis and miscarriage prevention effect and application thereof |
| CN104997922B (en) * | 2015-08-05 | 2017-11-21 | 南京中医药大学 | The refined extract of Chinese medicine composition with arresting bleeding and miscarriage prevention effect and its application |
| CN108175802A (en) * | 2018-01-30 | 2018-06-19 | 重庆芸峰药业有限公司 | A kind of FUKANGBAO KOUFUYE and preparation method thereof |
| CN108272981A (en) * | 2018-03-14 | 2018-07-13 | 江西地康药业有限公司 | Fukangbao koufuye |
| CN115607515A (en) * | 2022-11-04 | 2023-01-17 | 杭州市中医院 | Preparation process of spleen-tonifying miscarriage-preventing granules |
| CN115607515B (en) * | 2022-11-04 | 2024-01-16 | 杭州市中医院 | Preparation process of spleen-strengthening and miscarriage-preventing particles |
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