CN1269514C - Kidney supplementing life prolonging preparation and its making method - Google Patents

Kidney supplementing life prolonging preparation and its making method Download PDF

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Publication number
CN1269514C
CN1269514C CNB2004100466169A CN200410046616A CN1269514C CN 1269514 C CN1269514 C CN 1269514C CN B2004100466169 A CNB2004100466169 A CN B2004100466169A CN 200410046616 A CN200410046616 A CN 200410046616A CN 1269514 C CN1269514 C CN 1269514C
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China
Prior art keywords
radix
tablet
fine powder
ganoderma
prolonging life
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Expired - Lifetime
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CNB2004100466169A
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CN1596971A (en
Inventor
李叶华
江岩
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Kamp Pharmaceuticals Co Ltd
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YIXIAOTANG (HUNAN) PHARM Manufacturing CO Ltd
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Publication of CN1269514C publication Critical patent/CN1269514C/en
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Abstract

The present invention relates to a tablet for invigorating the kidney and prolonging life, particularly to a Chinese medical combination preparation. The tablet comprises the following main ingredients, in weight percentage: 2% to 5% of red ginseng, 0.1% to 1% of pearl, 5% to 15% of ganoderma lucidum, 15% to 25% of prepared fleeceflower root, 15% to 25% of barbary wolfberry fruit, 20% to 35% of epimedium herb, 5% to 15% of red sage root, 2% to 5% of radix glycyrrhiza, 5% to 15% of solomonseal rhizome and an amount of auxiliary materials. The preparation method comprises: the red ginseng and the pearl are pulverized into fine powder; the rest seven ingredients (comprising the ganoderma lucidum, etc.) are decocted with water twice; decoction liquids are mixed and filtered; the supernatant fluid is taken and concentrated into thick paste; an amount of starch is added in the thick paste; the thick paste with the starch is uniformly mixed, dried at low temperature and pulverized into fine powder; the fine powder is uniformly mixed with the powder of the red ginseng and the pearl and the auxiliary materials; the mixed powder is granulated and dried and then is pressed into a tablet by adding an amount of lubricant agent; and the tablet is coated with a film coat or not coated. The tablet for invigorating the kidney and prolonging life is prepared from medicaments and additives and has the advantages of good humidity resistance, convenient carrying, quick disintegration and small dosage.

Description

A kind of tonifying kidney and prolonging life preparation and preparation method thereof
Technical field:
The present invention relates to a kind of Chinese medicinal tablet and process for making thereof, relate in particular to tonifying kidney and prolonging life sheet and preparation method thereof.
Background technology:
Tablet, changes dosage form and manages as new drug research according to the relevant laws and regulations of China's drug control as a kind of pharmaceutical dosage form.Contain and the existing capsule of the essentially identical tonifying kidney and prolonging life preparation of this patent prescription drug, listed the national drug ministry standard in, but in the national standard and the concrete proportioning content of unexposed square medicine everywhere.
The technology features of existing capsule is after the recipe quantity medical material is partly pulverized, and remainder decocts, and filtrate is condensed into thick paste, adds suitable adjuvant and mixes, and granulation, drying promptly get capsule.
There is the relatively poor and easy shortcoming such as sticking esophagus of capsule when taking of humidity resistance in existing BUSHEN YISHOU JIAONANG.
Summary of the invention:
The purpose of this invention is to provide good tonifying kidney and prolonging life preparation of a kind of rapid disintegrate of energy, humidity resistance with good tonifying kidney and prolonging life function and preparation method thereof, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of tonifying kidney and prolonging life preparation, is a kind of Chinese medicine composition preparation, it is characterized in that it is that main component is the tablet of Radix Ginseng Rubra, Margarita, Ganoderma, Radix Polygoni Multiflori Preparata, Fructus Lycii, Herba Epimedii, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Rhizoma Polygonati.
The preparation method of tonifying kidney and prolonging life sheet is:
(1) main constituent and percentage by weight thereof are:
Radix Ginseng Rubra, each 2-5% of Radix Glycyrrhizae, Margarita 0.1-1%, Ganoderma, Radix Salviae Miltiorrhizae, each 5-15% of Rhizoma Polygonati, Radix Polygoni Multiflori Preparata, each 15-25% of Fructus Lycii, Herba Epimedii 20-35%;
(2) Radix Ginseng Rubra, Margarita powder are broken into fine powder, standby;
(3) seven flavors such as remaining Ganoderma are decocted with water secondary, collecting decoction filters, and gets supernatant concentration and becomes thick paste, adds appropriate amount of starch, mixing, and cold drying is ground into fine powder, and is standby;
(4) with (2) and the fine powder of (3) and an amount of adjuvant mix homogeneously, granulate, drying, standby;
Adjuvant is one or more a various combination in lactose, calcium sulfate, xylitol, microcrystalline Cellulose, polyvinylpolypyrrolidone, starch, dextrin, micropowder silica gel, low-substituted hydroxypropyl cellulose, the carboxymethyl starch sodium;
(5) will add suitable lubricant in (4) gained granule, compacting is in blocks, and plain sheet is coating or bag film-coat not;
Lubricant is one or more a various combination in magnesium stearate, Pulvis Talci, the micropowder silica gel.
In the above-mentioned preparation method, the optimum weight percentage ratio of main constituent is: Radix Ginseng Rubra, Radix Glycyrrhizae each 3.70%, Margarita 0.13%, Ganoderma, Radix Salviae Miltiorrhizae, Rhizoma Polygonati each 9.25%, Radix Polygoni Multiflori Preparata, Fructus Lycii each 18.49%, Herba Epimedii 27.74%;
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of tonifying kidney and prolonging life preparation is a kind of Chinese medicine composition preparation, and it is that a kind of main component is the tablet of Radix Ginseng Rubra, Margarita, Ganoderma, Radix Polygoni Multiflori Preparata, Fructus Lycii, Herba Epimedii, Radix Salviae Miltiorrhizae, Radix Glycyrrhizae, Rhizoma Polygonati.
To prepare 1000 tonifying kidney and prolonging life sheets is example, and preparation method is:
(1) consumption of getting the raw materials ready of main constituent is:
Radix Ginseng Rubra, each 126g of Radix Glycyrrhizae, Margarita 4.7g, Ganoderma, Radix Salviae Miltiorrhizae, each 315g of Rhizoma Polygonati, Radix Polygoni Multiflori Preparata, each 630g of Fructus Lycii, Herba Epimedii 945g;
(2) Radix Ginseng Rubra, Margarita powder are broken into fine powder, standby;
(3) seven flavors such as remaining Ganoderma are decocted with water secondary, collecting decoction filters, and gets supernatant concentration and becomes thick paste, adds appropriate amount of starch, mixing, and cold drying is ground into fine powder, and is standby;
(4) with (2) and the fine powder of (3) and an amount of adjuvant mix homogeneously, granulate, drying, standby;
Adjuvant is 5% starch, 5% microcrystalline Cellulose, 2% low-substituted hydroxypropyl cellulose, and its metering radix is the gross weight of fine powder.
(5) will add suitable lubricant in (4) gained granule, compacting is used coating premix mixture coating, promptly in flakes;
Lubricant is 1% micropowder silica gel, and its metering radix is the granule gross weight;
Advantage of the present invention is:
Product of the present invention has good tonifying kidney and prolonging life effect, and the tonifying kidney and prolonging life sheet is by medicine and filling Agent forms, and humidity resistance is good, is easy to carry, and rapidly disintegration, dose are little.

Claims (4)

1, a kind of tonifying kidney and prolonging life tablet, it is characterized in that making: Radix Ginseng Rubra, each 2-5% of Radix Glycyrrhizae, Margarita 0.1-1%, Ganoderma, Radix Salviae Miltiorrhizae, each 5-15% of Rhizoma Polygonati by following raw material medicines in percentage by weight, Radix Polygoni Multiflori Preparata, each 15-25% of Fructus Lycii, Herba Epimedii 20-35%.
2, a kind of tonifying kidney and prolonging life method for preparing tablet thereof is characterized in that:
(1) the crude drug percentage by weight is:
Radix Ginseng Rubra, each 2-5% of Radix Glycyrrhizae, Margarita 0.1-1%, Ganoderma, Radix Salviae Miltiorrhizae, each 5-15% of Rhizoma Polygonati, Radix Polygoni Multiflori Preparata, each 15-25% of Fructus Lycii, Herba Epimedii 20-35%;
(2) Radix Ginseng Rubra, Margarita powder are broken into fine powder, standby;
(3) seven flavors such as remaining Ganoderma are decocted with water secondary, collecting decoction filters, and gets supernatant concentration and becomes thick paste, adds appropriate amount of starch, mixing, and cold drying is ground into fine powder, and is standby;
(4) with (2) and the fine powder of (3) and an amount of adjuvant mix homogeneously, granulate, drying, standby;
Adjuvant is one or more a various combination in lactose, calcium sulfate, microcrystalline Cellulose, xylitol, polyvinylpolypyrrolidone, starch, dextrin, micropowder silica gel, low-substituted hydroxypropyl cellulose, the carboxymethyl starch sodium;
(5) will add suitable lubricant in (4) gained granule, compacting is in blocks, and plain sheet is coating or bag film-coat not;
Lubricant is one or more a various combination in magnesium stearate, Pulvis Talci, the micropowder silica gel.
3, tonifying kidney and prolonging life tablet according to claim 1 is characterized in that the percentage by weight of each crude drug is:
Radix Ginseng Rubra, Radix Glycyrrhizae each 3.70%, Margarita 0.13%, Ganoderma, Radix Salviae Miltiorrhizae, Rhizoma Polygonati each 9.25%, Radix Polygoni Multiflori Preparata, Fructus Lycii each 18.49%, Herba Epimedii 27.74%.
4, tonifying kidney and prolonging life method for preparing tablet thereof as claimed in claim 2 is characterized in that, the crude drug percentage by weight is: Radix Ginseng Rubra, Radix Glycyrrhizae each 3.70%, Margarita 0.13%, Ganoderma, Radix Salviae Miltiorrhizae, Rhizoma Polygonati each 9.25%, Radix Polygoni Multiflori Preparata, Fructus Lycii each 18.49%, Herba Epimedii 27.74%.
CNB2004100466169A 2004-07-30 2004-07-30 Kidney supplementing life prolonging preparation and its making method Expired - Lifetime CN1269514C (en)

Priority Applications (1)

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CN1269514C true CN1269514C (en) 2006-08-16

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102228505B (en) * 2007-12-14 2012-10-31 北京亚东生物制药有限公司 Chinese medicinal composition with effects of nourishing heart and tranquilizing mind and preparation method and detection method thereof

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105521277A (en) * 2014-09-30 2016-04-27 康普药业股份有限公司 Kidney tonifying and life prolonging dispersible tablet and preparation method thereof
CN106109921A (en) * 2016-08-28 2016-11-16 福州海王金象中药制药有限公司 Tonifying kidney and prolonging life sheet preparation technology
CN114425067A (en) * 2020-10-29 2022-05-03 康普药业股份有限公司 Kidney-tonifying life-prolonging preparation and quality control method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102228505B (en) * 2007-12-14 2012-10-31 北京亚东生物制药有限公司 Chinese medicinal composition with effects of nourishing heart and tranquilizing mind and preparation method and detection method thereof

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