CN1733205A - Tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and process for preparing the same - Google Patents
Tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and process for preparing the same Download PDFInfo
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- CN1733205A CN1733205A CN 200510031981 CN200510031981A CN1733205A CN 1733205 A CN1733205 A CN 1733205A CN 200510031981 CN200510031981 CN 200510031981 CN 200510031981 A CN200510031981 A CN 200510031981A CN 1733205 A CN1733205 A CN 1733205A
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- menorrhagia
- metrorrhagia
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- ipelvic
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Abstract
The invention provides a tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and process for preparation, which comprises: disintegrating rhizome of chinese paris into coarse powder, extracting by ethanol backflow, merging the extracts, filtrating, reclaiming ethanol from filtrate through decompression to make thick grease, dissolving the thick grease, filtering and separating with ceramic films, washing and trapping liquid, drying into dried grease, disintegrating the dried grease into mesh fines, passing through 80 mesh sieve, charging right amount of adjuvant, mixing homogenously, palletizing, tabletting, finally dressing to obtain the end product.
Description
Technical field:
The present invention relates to a kind of Chinese medicinal tablet and preparation method thereof, relate in particular to tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and preparation method thereof.
Background technology:
Tablet is a kind of pharmaceutical dosage form commonly used, according to the relevant laws and regulations of China's drug control, changes dosage form and manages as new drug research.The original dosage form of this product is a capsule, has listed the national drug standards in.
Existing GONGXUENING JIAONANG is to be the Chinese medicinal capsule agent that raw material is made with the Chinese medicine Rhizoma Paridis, it is with above-mentioned pulverizing medicinal materials, extraction, concentrate, drying, crushing screening, encapsulated, that is, GONGXUENING JIAONANG is used for the treatment of menorrhagia, metrorrhagia, chronic pelvic inflammatory disease disease.
The medicine stability of existing GONGXUENING JIAONANG is relatively poor, and inconvenience is produced, preserves, carries and used to the production cost height.
Summary of the invention:
It is good to the purpose of this invention is to provide a kind of medicine stability, production cost is lower, produce, preserve, carry and use more convenient, be used for the treatment of Chinese medicine preparation of menorrhagia, metrorrhagia, chronic pelvic inflammatory disease disease and preparation method thereof, overcome the above-mentioned drawback of prior art, improve the quality and the curative effect of product, satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation, is a kind of Chinese patent medicine that is used for the treatment of menorrhagia, metrorrhagia, chronic pelvic inflammatory disease disease, and it is to be the Chinese medicinal tablet that raw material is made with the Chinese crude drug Rhizoma Paridis.
A kind of preparation method of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation is characterized in that:
(1) get it filled thing composition and percentage by weight thereof is: 100% Rhizoma Paridis;
(2) get Rhizoma Paridis and be ground into coarse powder, add 70% alcohol reflux 2～5 times, add 2～10 times of amount 70% ethanol, each reflux, extract, 2～6 hours at every turn; Best for adding 4 times of amount 70% alcohol reflux three times, 5 hours for the first time, 4 hours for the second time, 3 hours for the third time, merge extractive liquid;
(3) get (2) multiple extraction gained extracting solution, filter, decompression filtrate recycling ethanol makes into thick paste, and the best is that decompression recycling ethanol is not received cream to there being alcohol flavor back, with the cream dissolving, with ceramic membrane (0.2 μ m) isolated by filtration, and carries out the proper dialysis washing;
(4) get (3) gained film trapped fluid spray drying, get dry extract; Or get (3) gained film trapped fluid and continue to be evaporated to the thick paste that relative density is 1.20～1.40 (60 ℃), vacuum drying gets dry extract; Best for getting (3) gained film trapped fluid spray drying, powder gets dry extract;
(5) get (4) and get dry extract, be ground into fine powder, cross 40～200 mesh sieves, powder gets dry extract; The best was 80 mesh sieves;
(6) get (5) gained dried cream powder, add appropriate amount of auxiliary materials, mixing is granulated, and tabletting, coating are promptly.
Specific embodiments:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation is a kind of Chinese patent medicine that is used for the treatment of menorrhagia, metrorrhagia, chronic pelvic inflammatory disease disease, and it is to be the new pharmaceutical dosage form that raw material is made with the Chinese medicine Rhizoma Paridis.
A kind of optimum implementation of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation preparation method is:
(1) get it filled thing composition and optimum weight percentage ratio thereof is: 100% Rhizoma Paridis.
(2) get Rhizoma Paridis and be ground into coarse powder, add four times of amount 70% alcohol reflux three times, 5 hours for the first time, 4 hours for the second time, 3 hours for the third time, merge extractive liquid,, filter, decompression filtrate recycling ethanol makes into thick paste, and thick paste is dissolved, with ceramic membrane (0.2 μ m) isolated by filtration, and carry out proper dialysis washing, film trapped fluid spray drying, dried cream powder is broken into the fine powder of 80 mesh sieves, added an amount of adjuvant, mixing, granulate, tabletting, coating are promptly.
Advantage of the present invention is: tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation is the new product that improves preparation technology and quality standard after formulation is improved, and is right Improving the quality of products is of great importance, and compares with existing Gongxuening capsule, and the present invention can guarantee the stable of medicine better Property reduces production costs, and is beneficial to production, preserves, carries and uses, be used for the treatment of menorrhalgia, uterine hemorrhage, The chronic pelvic inflammatory disease illness can satisfy needs of medical treatment better.
Claims (3)
1, a kind of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation is a kind of Chinese patent medicine that is used for the treatment of menorrhagia, metrorrhagia, chronic pelvic inflammatory disease disease, it is characterized in that it is is the tablet that raw material is made with the Rhizoma Paridis medical material.
2, a kind of preparation method of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation is characterized in that:
(1) get it filled thing composition and percentage by weight thereof is: 100% Rhizoma Paridis;
(2) get Rhizoma Paridis and be ground into coarse powder, add 70% alcohol reflux 2～5 times, add 2～10 times of amount 70% ethanol, each reflux, extract, 2～6 hours at every turn; Best for adding 4 times of amount 70% alcohol reflux three times, 5 hours for the first time, 4 hours for the second time, 3 hours for the third time, merge extractive liquid;
(3) get (2) multiple extraction gained extracting solution, filter, decompression filtrate recycling ethanol makes into thick paste, and the best is that decompression recycling ethanol is not received cream to there being alcohol flavor back, with the cream dissolving, with ceramic membrane (0.2 μ m) isolated by filtration, and carries out the proper dialysis washing;
(4) get (3) gained film trapped fluid spray drying, get dry extract; Or get (3) gained film trapped fluid and continue to be evaporated to the thick paste that relative density is 1.20～1.40 (60 ℃), vacuum drying gets dry extract; Best for getting (3) gained film trapped fluid spray drying, powder gets dry extract;
(5) get (4) and get dry extract, be ground into fine powder, cross 40～200 mesh sieves, powder gets dry extract; The best was 80 mesh sieves;
(6) get (5) gained dried cream powder, add appropriate amount of auxiliary materials, mixing is granulated, and tabletting, coating are promptly.
3, the preparation method of tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation according to claim 2 is characterized in that the optimum weight proportioning of its medicine composition is: 100% Rhizoma Paridis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510031981 CN1733205A (en) | 2005-08-08 | 2005-08-08 | Tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and process for preparing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510031981 CN1733205A (en) | 2005-08-08 | 2005-08-08 | Tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and process for preparing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1733205A true CN1733205A (en) | 2006-02-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN 200510031981 Pending CN1733205A (en) | 2005-08-08 | 2005-08-08 | Tablet for curing menorrhagia, metrorrhagia and chronic ipelvic inflammation and process for preparing the same |
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| CN (1) | CN1733205A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100464739C (en) * | 2006-07-28 | 2009-03-04 | 北京科信必成医药科技发展有限公司 | Dispersion tablets used as gynecologic hemostatic and its prepn. method |
| CN101856431A (en) * | 2010-06-02 | 2010-10-13 | 南京中医药大学 | Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof |
| CN111568989A (en) * | 2020-07-09 | 2020-08-25 | 山东中医药大学附属医院 | Application of cassia twig and rhizoma paridis dragon's blood extract in preparation of medicine for treating adenomyosis |
-
2005
- 2005-08-08 CN CN 200510031981 patent/CN1733205A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100464739C (en) * | 2006-07-28 | 2009-03-04 | 北京科信必成医药科技发展有限公司 | Dispersion tablets used as gynecologic hemostatic and its prepn. method |
| CN101856431A (en) * | 2010-06-02 | 2010-10-13 | 南京中医药大学 | Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof |
| CN101856431B (en) * | 2010-06-02 | 2011-08-31 | 南京中医药大学 | Medicament for treating liver-kidney yin deficiency type anovulatory dysfunctional uterine bleeding, and preparation method and application thereof |
| CN111568989A (en) * | 2020-07-09 | 2020-08-25 | 山东中医药大学附属医院 | Application of cassia twig and rhizoma paridis dragon's blood extract in preparation of medicine for treating adenomyosis |
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