CN1857655A - Compound Chinese medicine preparation for clearing away heat, drying damp, disinsecting and relieving itch and its preparing process - Google Patents

Abstract

The Chinese medicine preparation for treating persistent leucorrhea, vulva itching, etc. caused by vaginitis, cervicitis and other diseases is prepared with nine kinds of Chinese medicinal materials, including flavescent sophora root, cnidium fruit, rhubarb, sessile stemona root, dark plum, etc. The modern pharmaceutical research shows that the Chinese medicine preparation has the functions of clearing away heat, drying damp, disinsecting, relieving itch, etc; no LD50 detected through acute toxicity test, and no abnormality in blood picture and liver and kidney function indexes produced in long term toxicity test. Therefore, it is safe and effective.

Description

Compound Chinese medicinal preparation of a kind of heat clearing and damp drying, killing parasites for relieving itching and preparation method thereof

Technical field:

The invention belongs to field of medicaments, relate to a kind of heat clearing and damp drying, compound Chinese medicinal preparation of killing parasites for relieving itching and preparation method thereof is specifically related to a kind of the be used for leucorrhoea grow in quantity that vaginitis and cervicitis etc. cause, pharmaceutical preparation of diseases such as pruritus vulvae and preparation method thereof.

Background technology:

Vaginitis is a common gynecological disease, particularly when suffer from cold, tired, unhappy easily infected when causing the whole body defense function to descend, common have trichomonal vaginitis, colpitis mycotica, a youngest daughter's vaginitis etc., wherein common with trichomonal vaginitis, colpitis mycotica; Cervicitis is particularly a kind of commonly encountered diseases of middle-aged women of childbearing age women.Mechanical irritation or damage, microorganism and toxin thereof, chemical substance and lonizing radiation etc. all can become the cause of disease of cervicitis.Its cardinal symptom has leucorrhoea grow in quantity, waist and sacrum pain, pelvic cavity portion bearing down and dysmenorrhea, infertility and cervical erosion etc.

In order to seek effective clinical application, we develop this gynecological external use preparation, for vast female patient has brought Gospel by long-term theory research and in conjunction with clinical practice.This prescription is made up of medical materials such as Radix Sophorae Flavescentis, Fructus Cnidii, Radix Et Rhizoma Rhei, modern pharmacological research proves: said preparation has heat clearing and damp drying, effects such as killing parasites for relieving itching, anxious poison test fails to measure LD50, the hemogram of long term toxication and hepatic and renal function index and the equal no significant difference of matched group.Show that said preparation is safe and effective compound preparation.

Summary of the invention:

The invention provides a kind of heat clearing and damp drying, compound Chinese medicinal preparation of killing parasites for relieving itching and preparation method thereof.

Compound Chinese medicinal preparation of the present invention, it is characterized in that, make: Radix Sophorae Flavescentis 0.037-0.224, Fructus Cnidii 0.056-0.336, Radix Et Rhizoma Rhei 0.037-0.224, Radix Stemonae 0.037-0.224 Fructus Mume 0.037-0.224, Borax 0.028-0.168, Borneolum Syntheticum 0.0046-0.028, Alumen 0.0046-0.028, Radix Glycyrrhizae 0.0124-0.074 by the raw material of Chinese medicine of following weight ratio

Preferably:

Radix Sophorae Flavescentis 0.112, Fructus Cnidii 0.168, Radix Et Rhizoma Rhei 0.112, the Radix Stemonae 0.112, Fructus Mume 0.112, Borax 0.084, Borneolum Syntheticum 0.014, Alumen 0.014, Radix Glycyrrhizae 0.112

In more than forming, the weight of medicine is calculated with crude drug, and per 1 part can be 1 gram, also can be kilogram or ton.

More than form to be by weight as proportioning, when producing, can increase or reduce according to corresponding proportion, as large-scale production can be unit with the kilogram, or be unit with the ton, small-scale production can be unit with the milligram also, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.

The ratio of above weight proportion obtains through science screening, for especial patient, and as serious symptom or light disease, fat or modest patient, the proportioning of the amount of can corresponding adjustment forming increases or reduces being no more than 100%, and drug effect is constant.

In the capsule side of the present invention, use Borneolum Syntheticum: reducing swelling and alleviating pain, hold back skin ulcer hemostasis, logical gambling key, the stagnated fire of loosing, Radix Sophorae Flavescentis: heat clearing and damp drying, parasite killing are controlled insane, the malignant boil of scabies, Fructus Cnidii: effect such as strong positive kidney tonifying, dispeiling pathogenic wind and removing dampness, cold uterus, infertile, leucorrhea with red and white discharge, woman's pudendal pruritus has analgesic therapy, granulation promoting, holds back skin ulcer hemostasis, removing food stagnancy softening the hard mass, women's amenorrhea, face nevus, excellent.Various compatibility of drugss: bring out the best in each other, can kill and eliminate rubbish such as uterovaginal antibacterial, virus be old, making pudendum uterus granulation promoting play koro, to dispel pudendum gloomy, and play U.S. face.This medical instrument has heat clearing and damp drying, effects such as killing parasites for relieving itching.

The purpose of this invention is to provide a kind of external-applied capsules and preparation method that adopts pure treatment by Chinese herbs women gynaecopathia.The preparation method of compound medicinal formulation provided by the invention, can pass through following steps:

1) above nine flavors, Borneolum Syntheticum, Borax, Alumen are ground into fine powder;

2) Fructus Cnidii is ground into coarse powder; The five tastes such as all the other Radix Et Rhizoma Rhei decoct with water twice, add 10 times of amounts of water for the first time, decoct 1.5 hours, add 8 times of amounts of water for the second time, decoct 1 hour, and collecting decoction filters, and filtrate is concentrated into the clear paste that relative density is 1.10 (70～80 ℃);

3) clear paste adds the Fructus Cnidii coarse powder, stirs evenly, and drying is ground into fine powder, with fine powder mixing such as above-mentioned Borneolum Syntheticum, sieves, and incapsulates, promptly

External-applied capsules of the present invention is achieved through the following channels;

Prescription:

Radix Sophorae Flavescentis 112g Fructus Cnidii 168g Radix Et Rhizoma Rhei 112g

Radix Stemonae 112g Fructus Mume 112g Borax 84g

Borneolum Syntheticum 14g Alumen 14g Radix Glycyrrhizae 112g

Preparation method:

More than nine the flavor, Borneolum Syntheticum, Borax, Alumen are ground into fine powder; Fructus Cnidii is ground into coarse powder; The five tastes such as all the other Radix Et Rhizoma Rhei decoct with water twice, add 10 times of amounts of water for the first time, decoct 1.5 hours, for the second time add 8 times of amounts of water, decocted collecting decoction 1 hour, filter, it is 1.10 (70～80 ℃) that filtrate is concentrated into relative density, adds the Fructus Cnidii coarse powder, stir evenly, drying is ground into fine powder, with fine powder mixings such as above-mentioned Borneolum Syntheticums, sieve, incapsulate, make 1000, promptly.

Claims (3)

1. a treatment gynaecopathia external-applied capsules is characterized in that: make composition and press following weight proportion: Radix Sophorae Flavescentis 0.037-0.224, Fructus Cnidii 0.056-0.336, Radix Et Rhizoma Rhei 0.037-0.224, Radix Stemonae 0.037-0.224 Fructus Mume 0.037-0.224, Borax 0.028-0.168, Borneolum Syntheticum 0.004.6-0.028, Alumen 0.004.6-0.028 Radix Glycyrrhizae 0.012.4-0.074.

2. according to the described a kind of treatment gynaecopathia external-applied capsules of claim 1, it is characterized in that: the best composition of making is also by following weight proportion Radix Sophorae Flavescentis 0.112, Fructus Cnidii 0.168, Radix Et Rhizoma Rhei 0.112, the Radix Stemonae 0.112, Fructus Mume 0.112, Borax 0.084, Borneolum Syntheticum 0.014, Alumen 0.014, Radix Glycyrrhizae 0.112.

3. prepare the described a kind of treatment gynaecopathia external-applied capsules method of claim 1 for one kind, it is characterized in that: 1) above nine flavors, Borneolum Syntheticum, Borax, Alumen are ground into fine powder;

2) Fructus Cnidii is ground into coarse powder; The five tastes such as all the other Radix Et Rhizoma Rhei decoct with water twice, add 10 times of amounts of water for the first time, decoct 1.5 hours, add 8 times of amounts of water for the second time, decoct 1 hour, and collecting decoction filters, and filtrate is concentrated into the clear paste that relative density is 1.10 (70～80 ℃);

3) clear paste adds the Fructus Cnidii coarse powder, stirs evenly, and drying is ground into fine powder, with fine powder mixing such as above-mentioned Borneolum Syntheticum, sieves, and incapsulates, promptly.