CN1814122A - Medicine for treating osteoporosis and preparing method - Google Patents

Abstract

The invention relates to a medicine for curing osteoporosis and the preparing method thereof. And osteoporosis is one of the frequently seen and occuring diseases in clinical practice, and the old folks frequently suffer from osteoporosis. But the existing variouis medicinal preparations have single function and curative effects less than satisfactory. The invention is composed of Epimedium Herb, Himalayan Teasel Root, Danshen, Common Anemarrhena Rhizome, Malaytea Scurfpea Fruit, and Rehmannia Root according to Chinese medicinal theory, extracts their creams and fully plays the role in tonifying kidney and strengthening bones, and promoting the blood circulation and stopping pain. And its single use on trial in the clinic shows that it has remarkable curative effect and no bad reaction occurs after long-term taken, avoiding bad reaction of combined use of plural medicines and bad interaction between medicines.

Description

Medicine of treatment osteoporosis and preparation method thereof

One, technical field:

The present invention relates to a kind of medicine for the treatment of osteoporosis and preparation method thereof.

Two, technical background:

Osteoporosis is a common clinical, one of frequently-occurring disease.Up to nearly attention that just obtained people in 15 years gradually.This sick old people sees more, it is reported, nearly 200,000,000 people in the whole world suffer from osteoporosis at present, and its sickness rate has leapt to the 7th of the various commonly encountered diseases in the world.The sickness rate of China some areas senile osteoporosis disease more than 60 years old reaches 59.87%.International medical community is osteoporosis and hypertension, arteriosclerosis, and diabetes, tumor are listed as old people's important diseases.

Osteoporosis is a systemic disease, and the course of disease is long, and reaches 9.6% because of the incidence rate of the concurrent fracture of osteoporosis.The medical expense that fracture not only makes country and individual bear increases greatly, and has a strong impact on old people's quality of life.Osteoporosis is to reduce and the osseous tissue microstructure is a feature with whole body bone amount, and causes that the fragility of bone increases, and the intensity of bone lowers, in no wound, under the slight and moderate wound situation, the disease that the risk of fractures degree increases, bone mineral and bone matrix equal proportion minimizing this moment.

There is following thorny problem in the domestic and international at present Drug therapy to primary disease:

1 heavy dose of calcium preparation+vitamin D life-time service complication height, weak curative effect.

2 gonadal hormone have potential carcinogenic danger.

Can 3 calcitonins can only the intestinal external administration, costs an arm and a leg, long term administration remain to be observed.

4 diphosphonate adverse effectes are more, and effect is undesirable separately.

Though the Chinese patent medicine of some treatment osteoporosis is also arranged, Chinese medicine calcium preparation, or function blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, patent medicine such as Shujin bone strengthening and warming and recuperating the kidney-YANG, because of its function singleness, curative effect is then unsatisfactory.

Three, summary of the invention:

The object of the present invention is to provide medicine of a kind of treatment osteoporosis evident in efficacy and preparation method thereof.

For achieving the above object, the technical solution used in the present invention is:

A kind of medicine for the treatment of osteoporosis, its special character are that it is a medicament by the following weight proportion raw material:

Herba Epimedii 1027-1307 part Radix Dipsaci 147-187 part Radix Salviae Miltiorrhizae 73-93 part

Rhizoma Anemarrhenae 73-93 part Fructus Psoraleae 73-93 part Radix Rehmanniae 73-93 part

The medicine of above-mentioned treatment osteoporosis, the weight proportion of the best of its each raw material is:

83 parts of 167 parts of Radix Salviae Miltiorrhizaes of 1167 parts of Radix Dipsacis of Herba Epimedii

83 parts of 83 portions of Radix Rehmanniae of 83 parts of Fructus Psoraleaes of the Rhizoma Anemarrhenae

Above-mentioned medicament is the above dosage form of saying of any pharmaceutics.

Above-mentioned dosage form is that the processing step of preparation method of tablet is as follows:

(1), Radix Salviae Miltiorrhizae powder is broken into fine powder, sieve, standby;

(2), Herba Epimedii, Radix Dipsaci, the Rhizoma Anemarrhenae, Fructus Psoraleae are ground into coarse powder, Radix Rehmanniae is cut into, decocts with water three times, 3 hours for the first time, 2 hours for the first time, 1 hour for the first time, collecting decoction filters, and it is 1.20 clear paste that filtrate is concentrated into relative density, the Radix Salviae Miltiorrhizae fine powder that adds step (1) preparation, mixing is made, dry, tabletting, the bag film-coat gets final product.

The present invention is with respect to prior art, and its advantage is as follows:

1, to select natural Chinese medicinal herb for use be raw material in the present invention, based on the traditional theory of motherland's medical science, and in conjunction with the common disease type of clinical osteoporosis, with reference to the modern pharmacological research achievement, reasonable formula, and through animal and clinical experiment, have no side effect.

2, the present invention uses separately through clinic trial, and is evident in efficacy, takes for a long time and do not find untoward reaction.Remove the untoward reaction that multiple medicines share from, and mutual ill effect between the medicine.

Four, the specific embodiment:

The traditional theory that solution of the present invention is based on motherland's medical science is the basis, in conjunction with the common disease type of clinical osteoporosis, with reference to the modern pharmacological research achievement, from motherland's medicine treasure-house, filter out liver and kidney tonifying, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the natural drug of promoting the circulation of QI to relieve pain, by the theory of Chinese medical science prescription, skim the cream off milk, give full play to its invigorating the kidney and strengthening the bones, the merit of promoting blood circulation and stopping pain.With pure compound Chinese medicinal preparation, promptly remedied the deficiency of Western medicine, satisfied curative effect is arranged again.

Embodiment 1:

The medicine of treatment osteoporosis, the weight proportion of the best of its each raw material is:

Herba Epimedii 1167g Radix Dipsaci 167g Radix Salviae Miltiorrhizae 83g

Rhizoma Anemarrhenae 83g Fructus Psoraleae 83g Radix Rehmanniae 83g

Above-mentioned dosage form is that the processing step of preparation method of tablet is as follows:

(1), Radix Salviae Miltiorrhizae powder is broken into fine powder, sieve, standby;

(2), Herba Epimedii, Radix Dipsaci, the Rhizoma Anemarrhenae, Fructus Psoraleae are ground into coarse powder, Radix Rehmanniae is cut into, decocts with water three times, 3 hours for the first time, 2 hours for the first time, 1 hour for the first time, collecting decoction filters, and it is 1.20 clear paste that filtrate is concentrated into relative density, the Radix Salviae Miltiorrhizae fine powder that adds step (1) preparation, mixing is made, dry, tabletting, the bag film-coat gets final product.

Embodiment 2:

Take by weighing raw material by following proportioning:

Herba Epimedii 1027g Radix Dipsaci 147g Radix Salviae Miltiorrhizae 73g

Rhizoma Anemarrhenae 73g Fructus Psoraleae 73g Radix Rehmanniae 73g

Its preparation technology is identical with embodiment 1.

Embodiment 3:

Take by weighing raw material by following proportioning:

Herba Epimedii 1307g Radix Dipsaci 187g Radix Salviae Miltiorrhizae 93g

Rhizoma Anemarrhenae 93g Fructus Psoraleae 93g Radix Rehmanniae 93g

Its preparation technology is identical with embodiment 1.

Certainly, the present invention also can be prepared into the above dosage form of saying of any pharmaceutics, as dosage forms such as capsule, granules.

Claims (4)

1, a kind of medicine for the treatment of osteoporosis is characterized in that it is a medicament by the following weight proportion raw material:

Herba Epimedii 1027-1307 part Radix Dipsaci 147-187 part Radix Salviae Miltiorrhizae 73-93 part

Rhizoma Anemarrhenae 73-93 part Fructus Psoraleae 73-93 part Radix Rehmanniae 73-93 part

2, the medicine of treatment osteoporosis according to claim 1 is characterized in that: wherein the weight proportion of each raw material is:

83 parts of 167 parts of Radix Salviae Miltiorrhizaes of 1167 parts of Radix Dipsacis of Herba Epimedii

83 parts of 83 portions of Radix Rehmanniae of 83 parts of Fructus Psoraleaes of the Rhizoma Anemarrhenae

3, the medicine of treatment osteoporosis according to claim 1 and 2 is characterized in that: described medicament is the above dosage form of saying of any pharmaceutics.

4, the medicine of treatment osteoporosis according to claim 3 is characterized in that:

Described dosage form is that the processing step of preparation method of tablet is as follows:

(1), Radix Salviae Miltiorrhizae powder is broken into fine powder, sieve, standby;

(2), Herba Epimedii, Radix Dipsaci, the Rhizoma Anemarrhenae, Fructus Psoraleae are ground into coarse powder, Radix Rehmanniae is cut into, decocts with water three times, 3 hours for the first time, 2 hours for the first time, 1 hour for the first time, collecting decoction filters, and it is 1.20 clear paste that filtrate is concentrated into relative density, the Radix Salviae Miltiorrhizae fine powder that adds step (1) preparation, mixing is made, dry, tabletting, the bag film-coat gets final product.