CN1660212A - Oral preparation of Chinese traditional medicine of possessing function of adjusting blood sugar, and preparing method - Google Patents

Oral preparation of Chinese traditional medicine of possessing function of adjusting blood sugar, and preparing method Download PDF

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Publication number
CN1660212A
CN1660212A CN 200410066036 CN200410066036A CN1660212A CN 1660212 A CN1660212 A CN 1660212A CN 200410066036 CN200410066036 CN 200410066036 CN 200410066036 A CN200410066036 A CN 200410066036A CN 1660212 A CN1660212 A CN 1660212A
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China
Prior art keywords
rhizoma polygonati
radix puerariae
folium mori
lixiviate
preparation
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CN 200410066036
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Chinese (zh)
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CN1287837C (en
Inventor
沈建
陈晓红
钱一帆
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Zhongke Biochemistry Technology Co Ltd Nanjing
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Zhongke Biochemistry Technology Co Ltd Nanjing
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Priority to CN 200410066036 priority Critical patent/CN1287837C/en
Publication of CN1660212A publication Critical patent/CN1660212A/en
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Publication of CN1287837C publication Critical patent/CN1287837C/en
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Abstract

An orally taken Chinese medicine for regulating blood sugar is prepared from pueraria root, siberian solomon seal rhizome and mulberry leaf through pulverizing, proportionally mixing, immersion extracting, filtering, concentrating, spray drying and high-temp sterilizing.

Description

A kind of oral preparation of Chinese traditional medicinal and preparation method with blood sugar regulation function
Technical field
The present invention relates to Chinese medicine preparation, especially a kind of oral preparation of Chinese traditional medicinal and preparation method with blood sugar regulation function.
Background technology
Radix Puerariae has the effect of expelling pathogenic factors from muscles for reducing heat, invigorating YANG QI to promote eruption, promoting the production of body fluid to quench thirst.Can improve blood circulation, spasmolytic, blood sugar lowering, analgesic, improve learning and memory, control the disease that dysphoria with smothery sensation is quenched one's thirst, control the disease of hypertension, angina pectoris etc.Rhizoma Polygonati has the effect of lung moistening YIN nourishing, invigorating the spleen and replenishing QI, enriching kidney essence, also has the effect of blood sugar regulation.Folium Mori are sweet, bitter, cold, dispelling wind and heat pathogens, and clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving has the diabetes effect.。
Summary of the invention
The purpose of this invention is to provide a kind of oral preparation of Chinese traditional medicinal and preparation method with blood sugar regulation function, said preparation has good effect to regulating the blood sugar for human body level.Of the present invention theing contents are as follows:
A kind of oral preparation of Chinese traditional medicinal with blood sugar regulation function is characterized in that being made by following raw materials by weight percent: Radix Puerariae 50-65%, Rhizoma Polygonati 25-40%, Folium Mori 5-15%.Preferable raw materials by weight percent is mixed into: Radix Puerariae 60%, Rhizoma Polygonati 30%, Folium Mori 10%.The preparation method of above-mentioned oral preparation of Chinese traditional medicinal is characterized in that:
1) Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized, lixiviate in proportion feeds intake;
2) lixiviating solution concentrates after filtration, gets extract powder after the spray drying;
3) preparation fill behind the heat sterilization.
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, and fineness is about 20 orders; In Radix Puerariae: Rhizoma Polygonati: Folium Mori are that 60: 30: 10 ratio feeds intake, and the boiling water lixiviate is 3 hours in lixiviate is irritated, and filter, and filtering residue repeats lixiviate once, and merging filtrate is after concentrate, and spray drying gets extract powder.
Advantage of the present invention and effect: the present invention is raw material with the Radix Puerariae, adds Rhizoma Polygonati, Folium Mori, and the effect by three flavor Chinese medicines has the function of significant blood sugar regulation.Rhizoma Polygonati has the effect of lung moistening YIN nourishing, invigorating the spleen and replenishing QI, enriching kidney essence, also has the effect of blood sugar regulation.Folium Mori are sweet, bitter, cold, dispelling wind and heat pathogens, and clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving has the diabetes effect.Radix Puerariae, Rhizoma Polygonati, Folium Mori are all the kind of dietotherapeutic, and Radix Puerariae is equipped with Rhizoma Polygonati, Folium Mori, not only can strengthen the effect of blood sugar regulation, also can quench one's thirst that it is tired to separate, and enriching kidney essence also improves circulation, the many uncomfortable disease of improving hyperglycemia population.The test of Nanjing Medical University shows: this prescription does not have influence to normal mouse blood sugar and carbohydrate tolerance, has the effect that reduces the diabetic mice fasting glucose and improve the carbohydrate tolerance level.Through Nanjing Medical University's verification experimental verification, wherein the variation of the variation of fasting glucose and serum insulin (INS) is as follows before and after the Chinese medicine of this prescription of test-meal:
Blood glucose before the test-meal: 10.21 ± 2.75, blood glucose after the test-meal " 7.77 ± 1.17, reduce absolute value: 2.44 ± 2.52.Experimental example number: 32 examples.
INS:8.33mu/L ± 4.05mu/L before the test-meal, INS:8.40mu/L ± 3.42mu/L after the test-meal.Experimental example number: 30 examples.
The specific embodiment
Embodiment 1
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, and about 20 orders of fineness divide and get Radix Puerariae 61.2g, Rhizoma Polygonati 31.7g, and Folium Mori 11.0g, feeding intake enters hot water lixiviate operation, and boiling water lixiviate 3h in the lixiviate jar filters, concentrates, and obtains the concentrated solution preparation.
Embodiment 2
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, and about 10 orders of fineness divide and get Radix Puerariae 62.3g, Rhizoma Polygonati 29.5g, Folium Mori 9.6g, feeding intake enters hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar, filter, concentrate, get extract powder then after the spray drying, through pelletize, drying, tabletting obtains tablet.
Embodiment 3
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, and about 20 orders of fineness divide and get Radix Puerariae 48.0g, Rhizoma Polygonati 24.6g, Folium Mori 5.3g, feeding intake enters hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar, filter, concentrate, get extract powder then after the spray drying, through pelletize, drying, tabletting obtains tablet.
Embodiment 4
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, and about 20 orders of fineness divide and get Radix Puerariae 63.0g, Rhizoma Polygonati 30.8g, Folium Mori 9.6g, feeding intake enters hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar, filter, concentrate, get extract powder then after the spray drying, through pelletize, drying, tabletting obtains tablet.
Embodiment 5
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, and about 20 orders of fineness divide and get Radix Puerariae 65.4g, Rhizoma Polygonati 42.0g, Folium Mori 15.8g, feeding intake enters hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar, filter, concentrate, get extract powder then after the spray drying, through pelletize, drying, tabletting obtains tablet.
Embodiment 6
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, about 20 orders of fineness, divide and get Radix Puerariae 51.2g, Rhizoma Polygonati 23.7g, Folium Mori 6.2g, feed intake and enter hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar filters, concentrates, and gets extract powder then after the spray drying, carry out the capsule fill, every capsules content 0.25g.
Embodiment 7
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, about 20 orders of fineness, divide and get Radix Puerariae 61.5g, Rhizoma Polygonati 31.7g, Folium Mori 9.4g, feed intake and enter hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar filters, concentrates, and gets extract powder then after the spray drying, carry out the capsule fill, every capsules content 0.25g.
Embodiment 8
Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized with pulverizer respectively, about 20 orders of fineness, divide and get Radix Puerariae 64.9g, Rhizoma Polygonati 41.3g, Folium Mori 16.0g, feed intake and enter hot water lixiviate operation, boiling water lixiviate 3h in the lixiviate jar filters, concentrates, and gets extract powder then after the spray drying, carry out the capsule fill, every capsules content 0.25g.

Claims (4)

1, a kind of oral preparation of Chinese traditional medicinal with blood sugar regulation function is characterized in that being made by following raw materials by weight percent: Radix Puerariae 50-65%, Rhizoma Polygonati 25-40%, Folium Mori 5-15%.
2, oral preparation of Chinese traditional medicinal according to claim 1 is characterized in that being made by following raw materials by weight percent: Radix Puerariae 60%, Rhizoma Polygonati 30%, Folium Mori 10%.
3, the preparation method of oral preparation of Chinese traditional medicinal according to claim 1 and 2 is characterized in that:
1) Radix Puerariae, Rhizoma Polygonati, Folium Mori are pulverized, lixiviate in proportion feeds intake;
2) lixiviating solution concentrates after filtration, gets extract powder after the spray drying;
3) preparation fill behind the heat sterilization.
4, preparation method according to claim 3 is characterized in that Radix Puerariae, Rhizoma Polygonati, Folium Mori pulverize with pulverizer respectively, and fineness is about 20 orders; In Radix Puerariae: Rhizoma Polygonati: Folium Mori are that 60: 30: 10 ratio feeds intake, and the boiling water lixiviate is 3 hours in lixiviate is irritated, and filter, and filtering residue repeats lixiviate once, and merging filtrate is after concentrate, and spray drying gets extract powder.
CN 200410066036 2004-12-14 2004-12-14 Oral preparation of Chinese traditional medicine of possessing function of adjusting blood sugar, and preparing method Expired - Fee Related CN1287837C (en)

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CN1287837C CN1287837C (en) 2006-12-06

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101717713A (en) * 2009-11-16 2010-06-02 汪盛明 Method for processing polygonatum kudzuvine root distilled spirit
CN103860877A (en) * 2012-12-12 2014-06-18 石家庄以岭药业股份有限公司 Pharmaceutical composition for treating diabetes, and preparation method and application thereof
CN106491965A (en) * 2016-12-13 2017-03-15 四川天添生物科技应用有限公司 Can repairing pancreas β cells secrete insulins function be applied to type ii diabetes patient natural plant composition
CN106620537A (en) * 2017-02-05 2017-05-10 田歧都 Medicine for treating diabetes
CN106975012A (en) * 2017-05-18 2017-07-25 成都中医药大学 A kind of traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN107043669A (en) * 2017-04-26 2017-08-15 白汉玉 A kind of sealwort Yunnan olive health liquor
CN107087789A (en) * 2017-06-02 2017-08-25 重庆市中药研究院 A kind of yellow hypoglycemic Ultramicro-powder pharmaceutical formulation of mulberry Pueraria lobota and its application
CN109123296A (en) * 2018-08-01 2019-01-04 刘英奎 Pueraria lobata mulberry leaf compound solid beverage and preparation method
CN110367422A (en) * 2019-09-08 2019-10-25 李丽 A kind of rhizoma polygonati mulberry leaf compound solid beverage and preparation method thereof
CN114431384A (en) * 2022-01-27 2022-05-06 四川省川北人家农业科技有限公司 Mulberry leaf and sealwort instant beverage and preparation method thereof
CN114732869A (en) * 2021-01-07 2022-07-12 吴月英 Chinese medicinal composition for treating diabetes and preparation method thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101717713A (en) * 2009-11-16 2010-06-02 汪盛明 Method for processing polygonatum kudzuvine root distilled spirit
CN103860877A (en) * 2012-12-12 2014-06-18 石家庄以岭药业股份有限公司 Pharmaceutical composition for treating diabetes, and preparation method and application thereof
CN103860877B (en) * 2012-12-12 2019-01-08 石家庄以岭药业股份有限公司 A kind of pharmaceutical composition and its preparation method and application for treating diabetes
CN106491965A (en) * 2016-12-13 2017-03-15 四川天添生物科技应用有限公司 Can repairing pancreas β cells secrete insulins function be applied to type ii diabetes patient natural plant composition
CN106620537A (en) * 2017-02-05 2017-05-10 田歧都 Medicine for treating diabetes
CN107043669A (en) * 2017-04-26 2017-08-15 白汉玉 A kind of sealwort Yunnan olive health liquor
CN106975012A (en) * 2017-05-18 2017-07-25 成都中医药大学 A kind of traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN107087789A (en) * 2017-06-02 2017-08-25 重庆市中药研究院 A kind of yellow hypoglycemic Ultramicro-powder pharmaceutical formulation of mulberry Pueraria lobota and its application
CN109123296A (en) * 2018-08-01 2019-01-04 刘英奎 Pueraria lobata mulberry leaf compound solid beverage and preparation method
CN110367422A (en) * 2019-09-08 2019-10-25 李丽 A kind of rhizoma polygonati mulberry leaf compound solid beverage and preparation method thereof
CN114732869A (en) * 2021-01-07 2022-07-12 吴月英 Chinese medicinal composition for treating diabetes and preparation method thereof
CN114431384A (en) * 2022-01-27 2022-05-06 四川省川北人家农业科技有限公司 Mulberry leaf and sealwort instant beverage and preparation method thereof

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