CN1165695A

CN1165695A - Chinese Patent preparation

Info

Publication number: CN1165695A
Application number: CN 96102238
Authority: CN
Inventors: 徐文龙
Original assignee: Individual
Current assignee: Individual
Priority date: 1996-05-17
Filing date: 1996-05-17
Publication date: 1997-11-26

Abstract

A Chinese patent medicine in the form of capsule or instant particles is prepared from 7 Chinese-medicinal materials such as lucid ganoderma, astragalus root, red sage root, tuckahoe, epimedium, etc. through alcohol extraction of the first three, water extraction of others, mixing, concentration to become extract and making capsules or instant particles, and serves to cure fatigue and weak, anorexia, palpitation, insomnia, disturbed sleep, amnesia, etc.

Description

The Chinese patent medicine preparation and the processing method thereof of a kind of defying age, anti-fatigue

The present invention relates to a kind of Chinese patent medicine and processing method thereof, specifically a kind of defying age, antifatigue Chinese patent medicine preparation and and processing method thereof.

Syndrome of deficiency of both heart and spleen patient cardinal symptom has tired, weak, lazy speech, insomnia, dreaminess, cardiopalmus, yellowish complexion, become thin or puffiness due to deficiency, inappetence, feel dizzy, lip pale tongue etc., GUIPI WAN is effective Chinese patent medicine of this card of treatment, GUIPI WAN is monarch with the Rhizoma Atractylodis Macrocephalae, Radix Ginseng, and assistant processes the Radix Astragali, Radix Angelicae Sinensis, Radix Glycyrrhizae, Poria cum Radix Pini, Radix Polygalae, Semen Ziziphi Spinosae, the Radix Aucklandiae, Arillus Longan, Rhizoma Zingiberis Recens etc.CN1120938A 9,511,084 0.9 disclosed three-glue oral liquids are boiled by Colla Corii Asini, Colla Plastri Testudinis, Colla cornus cervi and 22 flavor rare Chinese medicines and form.

The present invention is intended to for the syndrome of deficiency of both heart and spleen patient and heart spleen is thanks to empty during getting old and weak, recovering, the disturbance of QI-blood person provides a kind of and fills blood, the Chinese patent medicine of heart-spleen boosting, reaches the purpose of strengthening the body resistance, life lengthening.

The Chinese medicine of preparation described in the present invention after by prescription is reprocessed molding after extracting effective ingredient wherein, or capsule or electuary, and prescription is as follows:

Ganoderma: 2 parts, the Radix Astragali: 2 parts,

Poria: 1 part, Radix Salviae Miltiorrhizae: 1 part,

Herba Epimedii: 1 part, Radix Trichosanthis: 1 part,

Fructus Jujubae: 1 part.

The processing method of preparation is as follows among the present invention:

Ganoderma, the Radix Astragali, Radix Salviae Miltiorrhizae three flavors are extractant with ethanol, and heating and refluxing extraction twice is separated the back and mixed twice ethanol extract, and ethanol is reclaimed in distilling under reduced pressure, obtains concentrated solution (I).

Ganoderma behind Poria, Herba Epimedii, Radix Trichosanthis, the same alcohol extraction of Fructus Jujubae four flavors, the Radix Astragali, Radix Salviae Miltiorrhizae (calling three flavor medicinal residues in the following text) are extractant together with water, twice of decoction or reflux, extract,, separate the back and mix twice aqueous extract, vacuum dehydration obtains concentrated solution (II).

Mixed concentrated liquid (I) and (II), condition of negative pressure continue precipitation down, obtain extractum, at last with the method molding of pharmacopeia regulation, or are processed into capsule, or are processed into electuary.

According to analysis of clinical, obeying dosage preparation day of the present invention is the extract that is equivalent to the former medicine of 25～30 grams, day clothes three times, and each dosage restrains former medicament extract for being equivalent to 8～10.The packing of capsule or electuary is by this standard metering.

Preparation have fill blood, the function of heart-spleen boosting, play defying age, antifatigue effect by regulating energy and blood of human body negative and positive and internal organs physiological function, thus strengthening the body resistance, life lengthening.Through Anhui Chinese Medicine College Affiliated Hospital, the II clinical trial phase of Affiliated Hospital of Medical University Of Anhui and system of Provincial Hospital proves, can significantly improve fatigue and weakness that deficiency of both the heart and spleen causes, spiritlessness and sparing of words, nervous cardiopalmus, insomnia and dreamful sleep, inappetence, the vexed loose stool of gastral cavity, feel dizzy, shallow complexion, multiple symptom such as easy catching a cold, total effective rate reaches 89.5%, suitable with the GUIPI WAN matched group, wherein the curative effect to fatigue and asthenia is higher than the GUIPI WAN matched group, the recovery rate that total white blood cells is reduced is 74.2%, also be higher than GUIPI WAN contrast fine horse, show that preparation also has curative effect preferably to leukopenia.Preparation especially is fit to patient old and that prolonged illness is just healed between convalescence and takes.Have no side effect.

Embodiment:

1, get Ganoderma 200 grams, the Radix Astragali 200 grams, Radix Salviae Miltiorrhizae 100 grams place distilling flask, drop into 1000 milliliters of 95% ethanol again, reflux 2 hours, cooled and filtered is collected filtrate, the alcohol reflux that the filtering residue reuse is 1000 milliliter 95% 1.5 hours, cooled and filtered, slag is stand-by.Mix filtrate twice, ethanol is reclaimed in distilling under reduced pressure, obtains concentrated solution (I).

Get Poria 100 grams, Herba Epimedii 100 grams, Radix Trichosanthis 100 grams, Fructus Jujubae 100 grams place distilling flask together with three flavor medicinal residues, drop into 1500 ml waters, reflux 2 hours, cooled and filtered is collected filtrate, filtering residue reuse 1500 ml water reflux, extract, 1.5 hours, cooled and filtered, slag discards.Mix filtrate twice, vacuum dehydration obtains concentrated solution (II).

Mixed concentrated liquid (I) and (II) continuation heating, vacuum precipitation obtain extractum, add pelletize behind cane sugar powder and the mixings such as supplementary product starch, dextrin, be drying to obtain clever stilbene electuary, 90～112 bags of packing, every bag of extract that is equivalent to the former medicine of 8～10 grams, day obeys three times, each 1 bag.

2, get Ganoderma 400 gram, the Radix Astragali 400 grams, Radix Salviae Miltiorrhizae 200 grams, 4000 milliliters of ethanol with 95% are reflux, extract, at twice, and operation gets concentrated solution (I) with embodiment 1.

Get Poria 200 grams, Herba Epimedii 200 restrains, Radix Trichosanthis 200 grams, and Fructus Jujubae 200 grams, three flavor medicinal residues, 6000 milliliters in water decocts at twice, and other are operated with embodiment 1, get concentrated solution (II).

Mixed concentrated liquid (I) and (II) continues heating, and the vacuum precipitation obtains extractum, this extractum drying, pulverize, add get final product in incapsulating behind the appropriate amount of auxiliary materials mixing clever astragalus capsules, adorn 720～900, be equivalent to the former medicament extract of 2～2.5 grams in every capsules, day obeys three times, each 4.

Claims

1, a kind of defying age, antifatigue Chinese patent medicine preparation are processed into capsule or electuary with the active ingredient that extracts prescription Chinese medicine, and it is characterized in that: described Chinese medicine is

Ganoderma: 2 parts, the Radix Astragali: 2 parts,

Poria: 1 part, Radix Salviae Miltiorrhizae: 1 part,

Herba Epimedii: 1 part, Radix Trichosanthis: 1 part,

Fructus Jujubae: 1 part.

2, a kind of defying age, antifatigue Chinese patent medicine preparation processing method are made of extraction, separation, precipitation, each unit process of molding, it is characterized in that:

(1), the Ganoderma in the prescription, the Radix Astragali and Radix Salviae Miltiorrhizae three flavors are extractant with ethanol, reflux, extract, twice is separated the back and is mixed twice ethanol extract, obtains concentrated solution (I) behind the precipitation;

(2), the Poria in the prescription, Herba Epimedii, Radix Trichosanthis and Fructus Jujubae four flavors are extractant with water with Ganoderma, the Radix Astragali and the Radix Salviae Miltiorrhizae behind the alcohol extraction together, decoct or reflux, extract, twice, separate the back and mix twice aqueous extract, obtain concentrated solution (II) after the dehydration;

(3), molding: mixed concentrated liquid (I) and (II), obtain extractum behind the precipitation, be processed into capsule or electuary by extractum.