CN1709293A - Composition for treating bee disease and medicinal fodder - Google Patents
Composition for treating bee disease and medicinal fodder Download PDFInfo
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- CN1709293A CN1709293A CNA2004100596995A CN200410059699A CN1709293A CN 1709293 A CN1709293 A CN 1709293A CN A2004100596995 A CNA2004100596995 A CN A2004100596995A CN 200410059699 A CN200410059699 A CN 200410059699A CN 1709293 A CN1709293 A CN 1709293A
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Abstract
The present invention provides a medicine composition for curing bee diseases of paralysis, dysentery and pest, etc. with obvious therapeutic effect. Said medicine composition is formed from (by weight portion) 1.5-3 portions of licorice, 0.5-2 portions of rhubarb, 1.5-2.5 portions of galangal root, 0.5-1.5 portions of bovine bezoar, 0.5-1.5 portions of atropa belladonna, 0.5-1.5 portions of ovate atractylodes root and 1-3 portions of isatis root.
Description
Technical field
The present invention relates to the field of Chinese medicines, relate in particular to the Chinese medicine composition and the pharmaceutical feed that are used for the treatment of honeybee disease.
Background technology
The bee colony of China becomes the honeybee commonly encountered diseases to have: bulky belly, bee paralysis, dysentery, bee spirochaetosis; Larva disease has: Chalk disease, American foulbrood, European foulbrood, Sacciform disease and Aspergillosis Huang etc.The disease that the disease of one-tenth honeybee all belongs to the intestines and stomach digestive system disease or causes thus.Larva disease all belongs to bacillary infringement and causes.For these diseases, China's bee colony life-time service antibiotic therapy and prevention.
The life-time service antibiotic certainly will make thalline produce powerful Drug resistance, causes the bee-keeper to continue to increase dose, but not only effect also makes the antibiotic remains severe overweight in the bee product still descending.According to investigations, 93% Mel contains antibiotic at 10ppm on the market, directly influences the outlet and the edibility of product, constitutes serious threat for the development of China's apiculture.
Summary of the invention
Technical problem to be solved by this invention provides a kind of compositions that is used for the treatment of above-mentioned honeybee disease.For this reason, the present invention by the following technical solutions: it mainly is made up of following bulk drugs: Radix Glycyrrhizae 1-5 part, Radix Et Rhizoma Rhei 0.1-2.5 part, Rhizoma Alpiniae Officinarum 1-3 part, Calculus Bovis 0.1-2 part, Semen daturae 0.1-2.5 part, Rhizoma Atractylodis Macrocephalae 0.1-2.5 part, Radix Isatidis 0.1-5 part.Its preferred group becomes: Radix Glycyrrhizae 1.5-3 part, Radix Et Rhizoma Rhei 0.5-2 part, Rhizoma Alpiniae Officinarum 1.5-2.5 part, Calculus Bovis 0.5-1.5 part, Semen daturae 0.5-1.5 part, Rhizoma Atractylodis Macrocephalae 0.5-1.5 part, Radix Isatidis 1-3 part.This compositions is pure Chinese herbal medicine formula, does not contain any antibiotic, hormone, and safe in utilization having no side effect can not caused negative effect to bee product when curing the disease.It is taken as the leading factor with the discharge of bacteria detoxifcation, mends smooth stomach for effect a permanent cure bulky belly, bee paralysis, dysentery, the bee spirochaetosis that can treat Apis comprehensively to support.Become honeybee health, larva is able to excellent length, improves the immunity of colony, prevents the pathogenic bacteria intrusion, reaches the effect of treatment larva chalk disease, American foulbrood, European foulbrood, Sacciform disease and Aspergillosis Huang, impels the bee colony benign cycle, the purpose that reaching takes stopgap measures effects a permanent cure.
Another technical problem to be solved of the present invention provides a kind of pharmaceutical feed that is used for the treatment of above-mentioned honeybee disease.For this reason, the present invention by the following technical solutions: its therapeutic activity composition is the water extract of above-mentioned raw materials drug composition or the extract of squeezing the juice.Except extract, also can add the sugar that accounts for extract weight percentage ratio 5%-20%, as white sugar, crystal sugar or fructose, with regard to fructose, can be such as the monosaccharide of glucose etc., so just can constitute pharmaceutical feed.Water extraction method of the present invention is for Chinese crude drug being carried out the common method of water extraction, such as the normal decocting method to medical material.The extraction of squeezing the juice of the present invention, also the common method of squeezing the juice and extracting for Chinese crude drug is squeezed the juice after crude drug is soaked.
The weight of crude drug compositions is general and the weight of its water extract or the weight of the extract of squeezing the juice etc. are heavy, certainly, also can not to wait heavy, this is just influential to the concentration of active component, in general, the weight ratio of the weight of the weight of crude drug compositions and its water extract or the extract of squeezing the juice is proper by 1: 1.5 at 1: 0.5.With weight ratio is example at 1: 1, its consumption is the feedstuff that every frame contains 5-10 gram extract every day, Apis goes back to the nest between the lights, pharmaceutical feed is sprayed on the honeybee road, sick group even fed 2 days, for above-mentioned honeybee disease, generally speaking, can disease controlling in the medication 12 hours, two days bee colonies of logotype are can rehabilitation normal.With regard to prevention, general every month 2-3 time, can make bee colony keep strong, improve immunity, remove and drag sub-phenomenon, improve royal jelly output.
The specific embodiment
Embodiment 1
Present embodiment provides the concrete preparation method of pharmaceutical feed.
With regard to water extraction method, can be normal decocting method to medical material.
Except that Calculus Bovis, each medical material is equipped with an amount of decocting system respectively, due-in dense after, add Calculus Bovis.The water yield that each medical material is joined can be such: the every weight portion of Radix Glycyrrhizae is joined 4-12 part water, the every weight portion of Radix Et Rhizoma Rhei is joined 2-7 part water, and the every weight portion of Rhizoma Alpiniae Officinarum is joined 3-9 part water, and the every weight portion of Semen daturae is joined 2-8 part water, the every weight portion of the Rhizoma Atractylodis Macrocephalae is joined 3-9 part water, and the every weight portion of Radix Isatidis is joined 3-9 part water.Receiving dense ratio is 1: 1
With regard to extracting with regard to squeezing the juice, also be the squeeze the juice common method of extraction of Chinese crude drug,
Crude drug added squeeze the juice after suitable quantity of water is soaked, the weight ratio of medical material weight and juice is 1: 1.
The sugar that in the extract for preparing, adds 5%-20%.
Embodiment 2
Present embodiment adopts prescription to be: 1.8 parts in Radix Glycyrrhizae, 0.6 part of Radix Et Rhizoma Rhei, 1.5 parts of Rhizoma Alpiniae Officinarum, 1.8 parts of Calculus Boviss, 1 part of Semen daturae, 0.8 part of the Rhizoma Atractylodis Macrocephalae, 2.2 parts of Radix Isatidiss.Method with embodiment 1 adds decocting, and extract and raw medicinal material etc. are heavy, adds the white sugar of percentage by weight 10% in the extract again, constitutes pharmaceutical feed.
The bee colony that the whole audience is suffered from bee paralysis is divided into three districts, uses pharmaceutical feed, chloromycetin and the check plot (not feeding any medicine) of present embodiment respectively.First day and second day, every group of pharmaceutical feeds that are fed with 50 gram extracts every day of pharmaceutical feed group, chloromycetin every group of hello 20,000 chloromycetin every day, all drug withdrawals after the 3rd day.It below is dead quantity statistical table.
As seen from the above table, behind twice of pharmaceutical feed of the present invention, the bee colony state of an illness is controlled fully, uses the chloromycetin district, and bee colony is slightly taken a favorable turn, but dead quantity is many, and after discontinuing medication, the state of an illness is still increasing the weight of, and the check plot state of an illness continues to worsen, and the bee colony straight line descends.Obviously, pharmaceutical feed of the present invention has obvious curative effects to bee paralysis, and thorough treatment, does not rebound after discontinuing medication.
To above same trial zone, after the 8th day, add up its royal jelly production in the beginning medication, see the following form:
| The 14th day | ?4308g | ??2150g | ??1905g |
| The 17th day | ?4329g | ??2090g | ??1673g |
| The 20th day | ?4329g | ??1856g | ??1420g |
| The 23rd day | ?4510g | ??1710g | ??1510g |
More than statistics shows, the bee colony of medicine feed thing feedstuff improves 98.24% than the royal jelly output of chloromycetin district bee colony, improves 131.69% than control group.
Embodiment 3
Present embodiment adopts prescription 1 to be: 2.7 parts in Radix Glycyrrhizae, 1.6 parts of Radix Et Rhizoma Rhei, 2.1 parts of Rhizoma Alpiniae Officinarum, 0.8 part of Calculus Bovis, 0.8 part of Semen daturae, 1 part of the Rhizoma Atractylodis Macrocephalae, 1 part of Radix Isatidis.Method with embodiment 1 adds decocting, and extract and raw medicinal material etc. are heavy, adds the glucose of percentage by weight 15% in the extract again, constitutes pharmaceutical feed 1.
The cooperation 2 that present embodiment adopts is: 3 parts in Radix Glycyrrhizae, 1.2 parts of Radix Et Rhizoma Rhei, 1.2 parts of Rhizoma Alpiniae Officinarum, 0.2 part of Calculus Bovis, 0.2 part of Semen daturae, 0.6 part of the Rhizoma Atractylodis Macrocephalae, 4 parts of Radix Isatidiss.Method with embodiment 1 is squeezed the juice, and extract and raw medicinal material etc. are heavy, adds the crystal sugar of percentage by weight 6% in the extract again, constitutes pharmaceutical feed 2.
The bee colony that the whole audience is suffered from bulky belly and larva disease is divided into four districts, uses pharmaceutical feed 1,2, kalamycin and the check plot (not feeding any medicine) of present embodiment respectively.First day and second day, every group of pharmaceutical feeds that are fed with 50 gram extracts every day of pharmaceutical feed group, kalamycin group every group of hello 20,000 kalamycins every day, whole drug withdrawal in the 3rd day, the 4th day.Five, the bee colony of six days kalamycin districts and check plot is used pharmaceutical feed 1 instead, and consumption is the same, and whole drug withdrawal in the 7th, eight day below is dead quantity statistical table, wherein the no dead honeybee of " nothing " representative.
As can be seen from the above table, pharmaceutical feed of the present invention has obvious curative effects to bulky belly; Become the honeybee rehabilitation, the larva disease natural remission, death obviously reduces, and does not have death until curing.Take effect during medication to some extent in the district with antibiotic, but in case discontinue medication state of an illness bounce-back obviously.After the pharmaceutical feed 1 of present embodiment was all adopted in antibiotic district and check plot, the state of an illness was cured fully, and obviously, pharmaceutical feed of the present invention has obvious curative effects to bulky belly and larva disease, and thorough treatment, does not rebound after discontinuing medication.
Embodiment 4
Present embodiment adopts prescription 1 to be: 4.5 parts in Radix Glycyrrhizae, 1.8 parts of Radix Et Rhizoma Rhei, 2.7 parts of Rhizoma Alpiniae Officinarum, 1.2 parts of Calculus Boviss, 1.8 parts of Semen daturae, 1.8 parts of the Rhizoma Atractylodis Macrocephalaes, 9 parts of Radix Isatidiss.Method with embodiment 1 adds decocting, and extract and raw medicinal material etc. are heavy, adds the white sugar of percentage by weight 12% in the extract again, to constitute pharmaceutical feed 1.
The cooperation 2 that present embodiment adopts is: 2.4 parts in Radix Glycyrrhizae, 2 parts of Radix Et Rhizoma Rhei, 1.9 parts of Rhizoma Alpiniae Officinarum, 1 part of Calculus Bovis, 1.9 parts of Semen daturae, 0.5 part of the Rhizoma Atractylodis Macrocephalae, 0.5 part of Radix Isatidis.Method with embodiment 1 is squeezed the juice, and extract and raw medicinal material etc. are heavy, adds the white sugar of percentage by weight 18% in the extract again, constitutes pharmaceutical feed 2.
The bee colony that the whole audience is suffered from dysentery and bee spirochaetosis is divided into four districts, uses pharmaceutical feed 1,2, kalamycin and the check plot (not feeding any medicine) of present embodiment respectively.First day and second day, every group of pharmaceutical feeds that are fed with 50 gram extracts every day of pharmaceutical feed group, kalamycin group hello 20,000 kalamycins every group of every days, whole drug withdrawal in the 3rd day, the 4th day.Five, the bee colony of six days kalamycin districts and check plot is used pharmaceutical feed 1 instead, and consumption is the same, and whole drug withdrawal in the 7th, eight day below is dead quantity statistical table, wherein the no dead honeybee of " nothing " representative.
As can be seen from the above table, pharmaceutical feed of the present invention has obvious curative effects to dysentery and bee spirochaetosis.Take effect during medication to some extent in the district with antibiotic, but in case discontinue medication state of an illness bounce-back obviously.After the pharmaceutical feed 1 of present embodiment was all adopted in antibiotic district and check plot, the state of an illness was cured fully, and obviously, pharmaceutical feed of the present invention has obvious curative effects to dysentery and bee spirochaetosis, and thorough treatment, does not rebound after discontinuing medication.
Claims (3)
1, a kind of compositions that is used for the treatment of honeybee disease is characterized in that it mainly is made up of following bulk drugs: Radix Glycyrrhizae 1-5 part, Radix Et Rhizoma Rhei 0.1-2.5 part; Rhizoma Alpiniae Officinarum 1-3 part, Calculus Bovis 0.1-2 part, Semen daturae 0.1-2.5 part; Rhizoma Atractylodis Macrocephalae 0.1-2.5 part, Radix Isatidis 0.1-5 part.
2, a kind of compositions that is used for the treatment of honeybee disease as claimed in claim 1 is characterized in that its preferred group becomes: Radix Glycyrrhizae 1.5-3 part, Radix Et Rhizoma Rhei 0.5-2 part; Rhizoma Alpiniae Officinarum 1.5-2.5 part, Calculus Bovis 0.5-1.5 part, Semen daturae 0.5-1.5 part; Rhizoma Atractylodis Macrocephalae 0.5-1.5 part, Radix Isatidis 1-3 part.
3, a kind of pharmaceutical feed that is used for Apis, the therapeutic activity composition that it is characterized in that it are the water extract or the extract of squeezing the juice of the crude drug compositions of claim 1 or 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100596995A CN1325107C (en) | 2004-06-17 | 2004-06-17 | Composition for treating bee disease and medicinal fodder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100596995A CN1325107C (en) | 2004-06-17 | 2004-06-17 | Composition for treating bee disease and medicinal fodder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1709293A true CN1709293A (en) | 2005-12-21 |
| CN1325107C CN1325107C (en) | 2007-07-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100596995A Expired - Fee Related CN1325107C (en) | 2004-06-17 | 2004-06-17 | Composition for treating bee disease and medicinal fodder |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357194B (en) * | 2008-09-11 | 2010-10-20 | 吴国良 | Traditional Chinese medicine for treating Pafeng disease |
| CN102836368A (en) * | 2012-09-10 | 2012-12-26 | 安徽省蜜蜂产业商会 | Chinese medicine composite for treating bee diseases and preparation method thereof |
| CN104127505A (en) * | 2014-07-06 | 2014-11-05 | 湖北天吉蜜业科技有限公司 | Chalkbrood eliminating granule Chinese patent medicine for treating bee chalkbrood disease and production technology thereof |
| CN105477173A (en) * | 2016-01-28 | 2016-04-13 | 张慧 | Medicine for bee colibacillosis |
| CN105641583A (en) * | 2016-01-26 | 2016-06-08 | 张慧 | Medicine for treating bee paralysis disease |
| CN105795167A (en) * | 2016-04-13 | 2016-07-27 | 山东新希望六和集团有限公司 | Bee feed additive |
| CN106036260A (en) * | 2016-07-14 | 2016-10-26 | 广西驰胜农业科技有限公司 | Bee breeding feed |
| CN106176886A (en) * | 2016-07-13 | 2016-12-07 | 熊明雷 | A kind of compositions for preventing and treating amebiasis of bee |
| CN106213071A (en) * | 2016-07-26 | 2016-12-14 | 陆川县乌石镇万意养蜂专业合作社 | A kind of Apis diseases prevention feedstuff and preparation method thereof |
| CN106260559A (en) * | 2016-08-08 | 2017-01-04 | 农玉金 | A kind of feed formula strengthening Apis immunologic function |
| CN106359305A (en) * | 2016-08-24 | 2017-02-01 | 覃政强 | Beekeeping method controlling bee crawling disease |
| CN107648392A (en) * | 2017-10-09 | 2018-02-02 | 桂阳神农蜂生态农业有限公司 | Pharmaceutical composition for honeybee epidemic prevention and control and preparation method thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055031B (en) * | 2012-12-05 | 2014-10-22 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating lime disease of bees and preparation method of pure Chinese medicinal composition |
-
2004
- 2004-06-17 CN CNB2004100596995A patent/CN1325107C/en not_active Expired - Fee Related
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101357194B (en) * | 2008-09-11 | 2010-10-20 | 吴国良 | Traditional Chinese medicine for treating Pafeng disease |
| CN102836368A (en) * | 2012-09-10 | 2012-12-26 | 安徽省蜜蜂产业商会 | Chinese medicine composite for treating bee diseases and preparation method thereof |
| CN104127505A (en) * | 2014-07-06 | 2014-11-05 | 湖北天吉蜜业科技有限公司 | Chalkbrood eliminating granule Chinese patent medicine for treating bee chalkbrood disease and production technology thereof |
| CN105641583A (en) * | 2016-01-26 | 2016-06-08 | 张慧 | Medicine for treating bee paralysis disease |
| CN105477173A (en) * | 2016-01-28 | 2016-04-13 | 张慧 | Medicine for bee colibacillosis |
| CN105795167A (en) * | 2016-04-13 | 2016-07-27 | 山东新希望六和集团有限公司 | Bee feed additive |
| CN106176886A (en) * | 2016-07-13 | 2016-12-07 | 熊明雷 | A kind of compositions for preventing and treating amebiasis of bee |
| CN106036260A (en) * | 2016-07-14 | 2016-10-26 | 广西驰胜农业科技有限公司 | Bee breeding feed |
| CN106213071A (en) * | 2016-07-26 | 2016-12-14 | 陆川县乌石镇万意养蜂专业合作社 | A kind of Apis diseases prevention feedstuff and preparation method thereof |
| CN106260559A (en) * | 2016-08-08 | 2017-01-04 | 农玉金 | A kind of feed formula strengthening Apis immunologic function |
| CN106359305A (en) * | 2016-08-24 | 2017-02-01 | 覃政强 | Beekeeping method controlling bee crawling disease |
| CN107648392A (en) * | 2017-10-09 | 2018-02-02 | 桂阳神农蜂生态农业有限公司 | Pharmaceutical composition for honeybee epidemic prevention and control and preparation method thereof |
| CN107648392B (en) * | 2017-10-09 | 2020-12-22 | 桂阳神农蜂生态农业有限公司 | Pharmaceutical composition for preventing and treating bee epidemic disease and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1325107C (en) | 2007-07-11 |
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Granted publication date: 20070711 |