CN101396438A - Traditional Chinese medicine oral liquid capable of relieving cough and asthma and use thereof in livestock and poultry - Google Patents
Traditional Chinese medicine oral liquid capable of relieving cough and asthma and use thereof in livestock and poultry Download PDFInfo
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- CN101396438A CN101396438A CNA2007100613053A CN200710061305A CN101396438A CN 101396438 A CN101396438 A CN 101396438A CN A2007100613053 A CNA2007100613053 A CN A2007100613053A CN 200710061305 A CN200710061305 A CN 200710061305A CN 101396438 A CN101396438 A CN 101396438A
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Abstract
The invention relates to traditional Chinese medicine compound oral liquid with the effects of clearing heat, removing toxin, reliving cough and eliminating phlegm, which contains two medicines of small-leaf banyan leaf and giant knotweed rhizome. The drug is applicable to respiratory tract infection of livestock and poultry, such as infectious bronchitis and other respiratory diseases. The formulation of the drug is also combined with the special physiological structure that the reproductive tract of the poultry is short and can not digest wood fibers, the drug is prepared into the oral liquid which can be rapidly dispersed in drinking water for feeding, and the drug delivery of the sick livestock and the poultry is carried out by drinking water, thereby facilitating and being conductive to the absorption and being able to achieve the purpose of rapid onset of action.
Description
Technical field
The invention belongs to field of veterinary, particularly relate to a kind of the have Chinese medicine oral liquid of heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect and the application on poultry thereof.
Background technology
In recent years, along with the expansion of intensive culture scale, the disease of each side such as the respiratory system disease of poultry, digestive system disease was more serious.Simultaneously because the abuse of antibiotics aspect livestock and poultry cultivation makes the problem of Resistant strain also more and more serious.
With the fowl respiratory system disease is example, and the outburst of respiratory system disease has had a strong impact on fowl weightening finish and efficiency of feed utilization, and laying rate is reduced, the carcass quality degradation, even cause a considerable amount of death, influenced the economic benefit of foster fowl.The respiratory tract disease of fowl is more complicated in foster fowl produces, and the kind of disease is a lot, has virus to cause, has antibacterial and mycoplasma to cause, M ﹠ M does not wait.Clinical manifestation is shed tears, rhinorrhea, cough or sneeze, breathe, symptom such as dyspnea.
At present, the medicine that adopt in market mostly is antibiotics, is used for treatment and prevention respiratory tract disease, though little, the instant effect of these medicine dosage often can not treat that it is basic, also makes bacterial strain produce drug resistance easily.Adopt the treatment by Chinese herbs livestock and birds respiratory disease to become one of effective treatment means.Yet the Chinese medicine preparation that uses clinically mostly is powder at present, exists the defective of administration inconvenience, and is short because of the digestive tract of fowl again, can not digest lignocellulose, caused problems such as drug absorption is poor, consumption is big.
Summary of the invention
Based on above-mentioned situation, the object of the present invention is to provide a kind of herbal mixture oral liquid with heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect.
The object of the present invention is achieved like this: a kind of Chinese traditional compound medicine with heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect is characterized in that: Folium fici microcarpae (drying in the shade) 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part.
Be preferably: 3 parts of Folium fici microcarpae (drying in the shade), 3 parts of Rhizoma Polygoni Cuspidati.
A kind of Chinese traditional compound medicine with heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect is characterized in that: the dosage form of described Chinese traditional compound medicine is an oral liquid.
Control according to the dialectical opinion of Chinese veterinarian, respiratory tract disease can be considered in the epidemic disease poison invades exuberant lung-stomach heat, stagnation of QI and blood.The rule of treatment is with heat-clearing and toxic substances removing, and anti-inflammation is main.Be principal agent with Folium fici microcarpae, Rhizoma Polygoni Cuspidati in the side, two herbal medicines share have eliminating phlegm and stopping cough, the effect of heat-clearing and toxic substances removing.
The present invention adopts the industry method in common to make: Folium fici microcarpae, Rhizoma Polygoni Cuspidati two flavor medical materials decoct with water secondary, 8 times of water gagings for the first time, and 6 times of water gagings for the second time, the back of at every turn boiling keeps little boiling 2 hours, and 200 mesh filter screens filter while hot.Merge filtrate twice, mixing is concentrated into every milliliter and is equivalent to crude drug in whole 1g, cold preservation 24 hours.Pulp board is supplied loss amount after filtering, and cold preservation is 24 hours again, and the amount with 3 ‰ after the cold preservation adds methyl parahydroxybenzoate, mixing, and flowing steam sterilization 30 minutes, quality inspection, fill, promptly.
Below with concrete description of test effect of the present invention:
1 material and method
1.1 trial drug
Medicine of the present invention, recommended dose are 4ml/, mix drink; Control drug: ZHIKE SAN, come from two ones of " People's Republic of China's veterinary drug allusion quotation " versions in 2005, per kilogram water is in crude drug 10g.
1.2 experimental animal
350 AA broiler available from the Tianjin suburban district chicken farm, go out to be transported in this laboratory pouity dwelling place behind the shell and raise in cages, Routine Management is fed to complete feed to 15 age in days, is for experiment after not having infectious bronchitis of chicken on inspection, be divided into seven groups of (medicine high dose group of the present invention at random, dosage group in the medicine of the present invention, medicine low dose group of the present invention, ZHIKE SAN control drug group, negative control group, positive controls, safe matched group), 50 every group.
1.3 artificial challenge
Except that negative control group and safe matched group, every plumage chicken is used 0.2ml avian infectious bronchitis virus M
41Strain collunarium counteracting toxic substances.All morbidities in 21-48 hour after the contamination, food or appetite are useless cuts off its cardinal symptom in order to subtract, and uneasy or drowsiness, happiness drink, poly-heap, crouching are crouched, and get rid of head, the sticking tears of stream, sneeze is breathed with cough, and trachea hello sound is arranged rare white soft stool; If the IB agar diffusion test is positive and then can makes a definite diagnosis, make a definite diagnosis back medication at once, observe therapeutic effect.
1.4 efficacy assessment standard
Duration of test, every day, observed and recorded was added up effective percentage, mortality rate and the relative weight gain rate after the course of treatment.
Chicken number * 100% before effective percentage (%)=treatment back survival chicken number/dispensing
Morbidity chicken number in sickness rate (%)=treatment/dispensing back chicken number * 100%
After the drug withdrawal 3 days, the medicine-feeding test chicken did not have obvious clinical symptoms, and the no typical cytopathic of inspection is cutd open in sampling, is judged to healing; Sx, anti-chicken excessively are effective in the therapeutic process.
1.5 test grouping and processing
Watch test grouping and processing
2 results
By table as can be seen, medicine height of the present invention, in, the relative weight gain of low dose group and medicine matched group is apparently higher than positive controls, death toll, mortality rate are starkly lower than positive controls, prove that medicine of the present invention and control drug are effectively to the infectious bronchitis of chicken, simultaneously also as can be seen the therapeutic effect of medicine of the present invention be better than the control drug group.
Beneficial effect of the present invention: prescription of the present invention has the effect of heat-clearing and toxic substances removing, eliminating phlegm and stopping cough, by clinical trial as can be seen, has good curative effect aspect the treatment livestock and birds respiratory disease.It is short that the dosage form of medicine of the present invention effectively combines the birds reproductive tract simultaneously, can not digest the special physiological structure of wood fibre, and medicine is made oral liquid, disperses rapidly in feeding drinking-water, after trouble fowl absorbs by drinking-water, can reach the purpose of rapid onset.
The specific embodiment
Embodiment 1: 1 part of Folium fici microcarpae (drying in the shade), and 1 part of Rhizoma Polygoni Cuspidati, two flavor medical materials decoct with water secondary, 8 times of water gagings for the first time, 6 times of water gagings for the second time, the back of at every turn boiling keeps little boiling 2 hours, and 200 mesh filter screens filter while hot.Merge filtrate twice, mixing is concentrated into every milliliter and is equivalent to crude drug in whole 1g, cold preservation 24 hours.Pulp board is supplied loss amount after filtering, and cold preservation is 24 hours again, and the amount with 3 ‰ after the cold preservation adds methyl parahydroxybenzoate, mixing, and flowing steam sterilization 30 minutes, quality inspection, fill, promptly.
Heat-clearing and toxic substances removing, eliminating phlegm and stopping cough.Be applicable to livestock and poultry respiratory tract infection, as respiratory system diseases such as infectious bronchitiss.Poultry: 4ml/, a twice-daily is freely drunk, logotype 3-5 days; The serious symptom doubled amount is used; Domestic animal: pig, cattle, the 1.6ml/kg body weight, a twice-daily is freely drunk, logotype 3-5 days.
Embodiment 2: 3 parts of Folium fici microcarpae (drying in the shade), and 3 parts of Rhizoma Polygoni Cuspidati, two flavor medical materials decoct with water secondary, 8 times of water gagings for the first time, 6 times of water gagings for the second time, the back of at every turn boiling keeps little boiling 2 hours, and 200 mesh filter screens filter while hot.Merge filtrate twice, mixing is concentrated into every milliliter and is equivalent to crude drug in whole 1g, cold preservation 24 hours.Pulp board is supplied loss amount after filtering, and cold preservation is 24 hours again, and the amount with 3 ‰ after the cold preservation adds methyl parahydroxybenzoate, mixing, and flowing steam sterilization 30 minutes, quality inspection, fill, promptly.
Heat-clearing and toxic substances removing, eliminating phlegm and stopping cough.Be applicable to livestock and poultry respiratory tract infection, as respiratory system diseases such as infectious bronchitiss.Poultry: 4ml/, a twice-daily is freely drunk, logotype 3-5 days; The serious symptom doubled amount is used; Domestic animal: pig, cattle, the 1.6ml/kg body weight, a twice-daily is freely drunk, logotype 3-5 days.
Embodiment 3: 5 parts of Folium fici microcarpae (drying in the shade), and 5 parts of Rhizoma Polygoni Cuspidati, two flavor medical materials decoct with water secondary, 8 times of water gagings for the first time, 6 times of water gagings for the second time, the back of at every turn boiling keeps little boiling 2 hours, and 200 mesh filter screens filter while hot.Merge filtrate twice, mixing is concentrated into every milliliter and is equivalent to crude drug in whole 1g, cold preservation 24 hours.Pulp board is supplied loss amount after filtering, and cold preservation is 24 hours again, and the amount with 3 ‰ after the cold preservation adds methyl parahydroxybenzoate, mixing, and flowing steam sterilization 30 minutes, quality inspection, fill, promptly.
Heat-clearing and toxic substances removing, eliminating phlegm and stopping cough.Be applicable to livestock and poultry respiratory tract infection, as respiratory system diseases such as infectious bronchitiss.Poultry: 4ml/, a twice-daily is freely drunk, logotype 3-5 days; The serious symptom doubled amount is used; Domestic animal: pig, cattle, the 1.6ml/kg body weight, a twice-daily is freely drunk, logotype 3-5 days.
Claims (3)
1, a kind of Chinese medicine oral liquid with heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect is characterized in that: Folium fici microcarpae (drying in the shade) 1-5 part, Rhizoma Polygoni Cuspidati 1-5 part.
2, a kind of Chinese medicine oral liquid with heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect according to claim 1 is characterized in that optimizing prescriptions of the present invention is: 3 parts of Folium fici microcarpae (drying in the shade), 3 parts of Rhizoma Polygoni Cuspidati.
3, a kind of Chinese medicine oral liquid with heat-clearing and toxic substances removing, eliminating phlegm and stopping cough effect according to claim 1, it is characterized in that: the dosage form of described Chinese traditional compound medicine is an oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100613053A CN101396438A (en) | 2007-09-30 | 2007-09-30 | Traditional Chinese medicine oral liquid capable of relieving cough and asthma and use thereof in livestock and poultry |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007100613053A CN101396438A (en) | 2007-09-30 | 2007-09-30 | Traditional Chinese medicine oral liquid capable of relieving cough and asthma and use thereof in livestock and poultry |
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| Publication Number | Publication Date |
|---|---|
| CN101396438A true CN101396438A (en) | 2009-04-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007100613053A Pending CN101396438A (en) | 2007-09-30 | 2007-09-30 | Traditional Chinese medicine oral liquid capable of relieving cough and asthma and use thereof in livestock and poultry |
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| CN (1) | CN101396438A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028755A (en) * | 2010-12-23 | 2011-04-27 | 天津康莱森生物科技集团有限公司 | Preparation method of traditional Chinese medicine aerosol for treating respiratory system diseases of birds |
| CN102949456A (en) * | 2011-08-30 | 2013-03-06 | 江守训 | Preparation method of ficus microcarpa extract and medicament or wound binder for promoting wound healing |
-
2007
- 2007-09-30 CN CNA2007100613053A patent/CN101396438A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102028755A (en) * | 2010-12-23 | 2011-04-27 | 天津康莱森生物科技集团有限公司 | Preparation method of traditional Chinese medicine aerosol for treating respiratory system diseases of birds |
| CN102028755B (en) * | 2010-12-23 | 2012-02-22 | 天津康莱森生物科技集团有限公司 | Preparation method of traditional Chinese medicine aerosol for treating respiratory system diseases of birds |
| CN102949456A (en) * | 2011-08-30 | 2013-03-06 | 江守训 | Preparation method of ficus microcarpa extract and medicament or wound binder for promoting wound healing |
| CN102949456B (en) * | 2011-08-30 | 2015-01-21 | 江守训 | Preparation method of ficus microcarpa extract and medicament or wound binder for promoting wound healing |
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| WD01 | Invention patent application deemed withdrawn after publication |
Open date: 20090401 |