CN1634611A - 心肌修复支架的制备及应用 - Google Patents
心肌修复支架的制备及应用 Download PDFInfo
- Publication number
- CN1634611A CN1634611A CN 200410090612 CN200410090612A CN1634611A CN 1634611 A CN1634611 A CN 1634611A CN 200410090612 CN200410090612 CN 200410090612 CN 200410090612 A CN200410090612 A CN 200410090612A CN 1634611 A CN1634611 A CN 1634611A
- Authority
- CN
- China
- Prior art keywords
- stem cell
- cardiac muscle
- bone marrow
- muscle repair
- cardiac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004165 myocardium Anatomy 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 230000008439 repair process Effects 0.000 title claims description 26
- 210000000130 stem cell Anatomy 0.000 claims abstract description 26
- 102000008186 Collagen Human genes 0.000 claims abstract description 25
- 108010035532 Collagen Proteins 0.000 claims abstract description 25
- 239000000463 material Substances 0.000 claims abstract description 17
- 210000001185 bone marrow Anatomy 0.000 claims abstract description 15
- 239000007787 solid Substances 0.000 claims abstract description 9
- 241001465754 Metazoa Species 0.000 claims abstract description 6
- 108091005804 Peptidases Proteins 0.000 claims abstract description 5
- 239000004365 Protease Substances 0.000 claims abstract description 5
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract description 5
- 239000002253 acid Substances 0.000 claims abstract description 5
- 239000003513 alkali Substances 0.000 claims abstract description 5
- 210000002808 connective tissue Anatomy 0.000 claims abstract description 5
- 230000001954 sterilising effect Effects 0.000 claims abstract description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 4
- 229920001436 collagen Polymers 0.000 claims description 15
- 230000000747 cardiac effect Effects 0.000 claims description 14
- 230000003387 muscular Effects 0.000 claims description 14
- 239000000284 extract Substances 0.000 claims description 8
- 210000004027 cell Anatomy 0.000 claims description 6
- 208000019622 heart disease Diseases 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 5
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 claims description 4
- 229920001287 Chondroitin sulfate Polymers 0.000 claims description 4
- 239000002585 base Substances 0.000 claims description 4
- 229940059329 chondroitin sulfate Drugs 0.000 claims description 4
- 208000020446 Cardiac disease Diseases 0.000 claims description 3
- 239000003431 cross linking reagent Substances 0.000 claims description 3
- 230000017423 tissue regeneration Effects 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 abstract description 16
- 238000001035 drying Methods 0.000 abstract description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 2
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000006378 damage Effects 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 210000001951 dura mater Anatomy 0.000 description 2
- 239000010408 film Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000003683 cardiac damage Effects 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200410090612 CN1250298C (zh) | 2004-11-10 | 2004-11-10 | 心肌修复支架的制备及应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200410090612 CN1250298C (zh) | 2004-11-10 | 2004-11-10 | 心肌修复支架的制备及应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1634611A true CN1634611A (zh) | 2005-07-06 |
CN1250298C CN1250298C (zh) | 2006-04-12 |
Family
ID=34847599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 200410090612 Ceased CN1250298C (zh) | 2004-11-10 | 2004-11-10 | 心肌修复支架的制备及应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN1250298C (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106552294A (zh) * | 2015-09-25 | 2017-04-05 | 上海市东方医院 | 一种用于心脏修复的生物补片材料 |
CN107496995A (zh) * | 2017-09-30 | 2017-12-22 | 江苏瑞腾涂装科技有限公司 | 一种心脏支架用组合物 |
-
2004
- 2004-11-10 CN CN 200410090612 patent/CN1250298C/zh not_active Ceased
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106552294A (zh) * | 2015-09-25 | 2017-04-05 | 上海市东方医院 | 一种用于心脏修复的生物补片材料 |
CN106552294B (zh) * | 2015-09-25 | 2021-06-01 | 上海市东方医院 | 一种用于心脏修复的生物补片材料 |
CN107496995A (zh) * | 2017-09-30 | 2017-12-22 | 江苏瑞腾涂装科技有限公司 | 一种心脏支架用组合物 |
Also Published As
Publication number | Publication date |
---|---|
CN1250298C (zh) | 2006-04-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105935454A (zh) | 一种脱细胞基质源组织工程支架及其制备方法和应用 | |
ES2275147T3 (es) | Composicion para regeneracion de tejidos. | |
CN108744023A (zh) | 一种丝素蛋白医用生物粘合剂及其制备方法 | |
CN103251649B (zh) | 人间充质干细胞培养上清液冻干粉的制备方法 | |
CN101773687B (zh) | 一种复合软组织补片的制备方法 | |
JP2005524426A (ja) | 血管新生が促進された移植片構成物 | |
MX2012008215A (es) | Construcciones de tejido bio-diseñadas por ingenieria y metodos para la produccion y uso de las mismas. | |
BR112014023404B1 (pt) | emplastro biocompatível | |
CN110478528B (zh) | 一种新型的促组织修复材料的制备方法及其应用 | |
CN205073351U (zh) | 一种脱细胞基质源的口腔补片 | |
CN103805555A (zh) | 骨骼肌全器官脱细胞基质、制备方法及其衍生出的医疗产品 | |
CN100368534C (zh) | 生物衍生羊膜、复合生物衍生羊膜及其制备方法 | |
CN109453200A (zh) | 多组织来源的间充质干细胞裂解因子冻干粉的制备方法 | |
CN112870445A (zh) | 一种软组织修复材料的制备方法及应用 | |
CN1250298C (zh) | 心肌修复支架的制备及应用 | |
CN100402097C (zh) | 琼脂/胶原皮肤创伤修复敷料及其制备方法和应用 | |
CN110711264B (zh) | 复合材料、医用粘合剂及其制备方法和应用 | |
CN105833357B (zh) | 一种易保存生物羊膜的制备方法 | |
CN112426402A (zh) | 一种基于成纤维外泌体的敷贴及制备方法 | |
CN110507854A (zh) | 骨移植植入物及其制备方法 | |
CN106913908A (zh) | 一种具有结构记忆特性的细胞生长支架 | |
CN100366303C (zh) | 肌腱、韧带防粘连生物膜的制备及应用 | |
CN101822851A (zh) | 一种组织工程骨软骨支架及其制备方法 | |
US7175979B2 (en) | Preserved tissue matrix of a hollow organ, particularly of a blood vessel, a method of producing same, and the use thereof | |
CN109498841B (zh) | 一种生物型骨膜修复材料及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Beijing Tianxinfu Medical Equipment Co.,Ltd. Assignor: Yu Haiying Contract fulfillment period: 2009.8.18 to 2014.8.18 Contract record no.: 2009110000181 Denomination of invention: Preparation and application of cardiac muscle repair stent Granted publication date: 20060412 License type: Exclusive license Record date: 20090825 |
|
LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2009.8.18 TO 2014.8.18; CHANGE OF CONTRACT Name of requester: BEIJING TIANXINFU MEDICAL TREATMENT EQUIPMENT CO., Effective date: 20090825 |
|
DD01 | Delivery of document by public notice |
Addressee: Liu Jun Document name: Notice of Conformity |
|
DD01 | Delivery of document by public notice | ||
DD01 | Delivery of document by public notice |
Addressee: Beijing Huaxia Botong Patent Agency Document name: Notice of Transmittal of Documents (Patent Holder) |
|
DD01 | Delivery of document by public notice | ||
IW01 | Full invalidation of patent right |
Decision date of declaring invalidation: 20230802 Decision number of declaring invalidation: 562771 Granted publication date: 20060412 |
|
IW01 | Full invalidation of patent right |