CN1575342A - 测定多重分析物的方法 - Google Patents

测定多重分析物的方法 Download PDF

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Publication number
CN1575342A
CN1575342A CNA028212398A CN02821239A CN1575342A CN 1575342 A CN1575342 A CN 1575342A CN A028212398 A CNA028212398 A CN A028212398A CN 02821239 A CN02821239 A CN 02821239A CN 1575342 A CN1575342 A CN 1575342A
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CN
China
Prior art keywords
binding partner
label
specific
coupled
analyte
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Pending
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CNA028212398A
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English (en)
Chinese (zh)
Inventor
K·魏因德尔
S·克赖斯
F·贝格曼
H·-P·约瑟尔
D·海因德尔
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of CN1575342A publication Critical patent/CN1575342A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CNA028212398A 2001-08-28 2002-08-24 测定多重分析物的方法 Pending CN1575342A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01120466A EP1288308A1 (en) 2001-08-28 2001-08-28 A method for the determination of multiple analytes
EP01120466.6 2001-08-28

Publications (1)

Publication Number Publication Date
CN1575342A true CN1575342A (zh) 2005-02-02

Family

ID=8178429

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028212398A Pending CN1575342A (zh) 2001-08-28 2002-08-24 测定多重分析物的方法

Country Status (14)

Country Link
US (1) US20040191794A1 (enExample)
EP (2) EP1288308A1 (enExample)
JP (1) JP4559074B2 (enExample)
KR (1) KR100653156B1 (enExample)
CN (1) CN1575342A (enExample)
AT (1) ATE333522T1 (enExample)
AU (1) AU2002361779B2 (enExample)
BR (1) BR0212265B1 (enExample)
DE (1) DE60213256T2 (enExample)
DK (1) DK1423541T3 (enExample)
ES (1) ES2269804T3 (enExample)
MX (1) MXPA04001730A (enExample)
PL (1) PL210867B1 (enExample)
WO (1) WO2003020967A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106574925A (zh) * 2014-05-23 2017-04-19 萤火虫生物股份有限公司 用于生物测定的底物介导的反应器
CN108841939A (zh) * 2018-06-21 2018-11-20 北京致雨生物科技有限公司 多重数字pcr浓度测量方法及微滴式数字pcr系统
CN112805392A (zh) * 2018-07-11 2021-05-14 克罗玛科德公司 多重生化反应中分析物的定量方法
CN113195734A (zh) * 2018-12-20 2021-07-30 豪夫迈·罗氏有限公司 通过固相分子成像检测靶核酸

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7385043B1 (en) * 2003-04-30 2008-06-10 The Public Health Research Institute Of The City Of New York, Inc. Homogeneous multiplex screening assays and kits
WO2005111243A2 (en) * 2004-05-07 2005-11-24 Cepheid Multiplexed detection of biological agents
JP4753943B2 (ja) 2004-07-13 2011-08-24 ジェン−プローブ・インコーポレーテッド Ａ型肝炎ウイルス核酸の検出のための組成物及び方法
EP1930716A1 (de) * 2006-12-08 2008-06-11 Micronas GmbH Verfahren und Vorrichtung zur Detektion eines Liganden in einem Fluid
US20110024307A1 (en) 2009-07-02 2011-02-03 Dexcom, Inc. Analyte sensor
CA2853917A1 (en) * 2011-12-19 2013-06-27 F. Hoffmann-La Roche Ag Method for the detection of free binding partner of a multispecific binder
CN107326085B (zh) 2012-02-03 2022-05-03 加州理工学院 多路生化测定中信号的编码和解码
WO2014022827A1 (en) 2012-08-03 2014-02-06 California Institute Of Technology Multiplexing and quantification in pcr with reduced hardware and requirements
US10829816B2 (en) 2012-11-19 2020-11-10 Apton Biosystems, Inc. Methods of analyte detection
TWI611174B (zh) 2013-04-15 2018-01-11 瓦拉克公司 用於串音校正測量強度之方法、裝置及電腦程式、具有用於串音校正測量強度之裝置的測量儀器、以及具有編碼有電腦程式之非暫態電腦可讀取媒體的電腦程式產品
EP3595806A4 (en) 2017-03-17 2021-06-16 Apton Biosystems, Inc. SEQUENCING AND HIGH RESOLUTION IMAGING
KR101871985B1 (ko) * 2017-08-14 2018-06-27 고려대학교 산학협력단 3차원 단백질 나노입자 프로브 기반 복수 질환의 동시검출 방법 및 키트
US12454720B2 (en) 2018-04-17 2025-10-28 ChromaCode, Inc. Methods and systems for multiplex analysis
US12203129B2 (en) * 2018-07-03 2025-01-21 ChromaCode, Inc. Formulations and signal encoding and decoding methods for massively multiplexed biochemical assays
EP3853382A4 (en) 2018-09-19 2022-06-22 Apton Biosystems, Inc. Densely-packed analyte layers and detection methods
US20220049303A1 (en) * 2020-08-17 2022-02-17 Readcoor, Llc Methods and systems for spatial mapping of genetic variants
CN112485439B (zh) * 2020-11-10 2023-07-18 深圳市科曼医疗设备有限公司 特定蛋白质反应检测方法、蛋白质检测装置和定标方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991011534A1 (en) * 1990-01-24 1991-08-08 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce A rapid and sensitive test for detecting hepatitis a virus
US5834248A (en) * 1995-02-10 1998-11-10 Millennium Pharmaceuticals Inc. Compositions and methods using rchd534, a gene uregulated by shear stress
US5759781A (en) * 1995-12-22 1998-06-02 Yale University Multiparametric fluorescence in situ hybridization
US6007994A (en) * 1995-12-22 1999-12-28 Yale University Multiparametric fluorescence in situ hybridization
JP2000507809A (ja) * 1996-05-01 2000-06-27 エール・ユニバーシティ マルチパラメーター蛍光ｉｎ ｓｉｔｕハイブリダイゼーション
DE19723463A1 (de) * 1997-06-04 1998-12-10 Dade Behring Marburg Gmbh Immunchemische Bestimmung von multivalenten Analyten
EP0953837A1 (en) * 1998-05-01 1999-11-03 F. Hoffmann-La Roche Ag Fluorescence light measuring device and an apparatus wherein such a device is used
AU758466B2 (en) * 1998-06-02 2003-03-20 Yale University Multiparametric fluorescence in situ hybridization

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106574925A (zh) * 2014-05-23 2017-04-19 萤火虫生物股份有限公司 用于生物测定的底物介导的反应器
CN106574925B (zh) * 2014-05-23 2019-07-26 萤火虫生物股份有限公司 用于生物测定的底物介导的反应器
CN108841939A (zh) * 2018-06-21 2018-11-20 北京致雨生物科技有限公司 多重数字pcr浓度测量方法及微滴式数字pcr系统
CN112805392A (zh) * 2018-07-11 2021-05-14 克罗玛科德公司 多重生化反应中分析物的定量方法
CN113195734A (zh) * 2018-12-20 2021-07-30 豪夫迈·罗氏有限公司 通过固相分子成像检测靶核酸

Also Published As

Publication number Publication date
KR20040029076A (ko) 2004-04-03
WO2003020967A1 (en) 2003-03-13
PL369239A1 (en) 2005-04-18
ES2269804T3 (es) 2007-04-01
PL210867B1 (pl) 2012-03-30
KR100653156B1 (ko) 2006-12-01
EP1423541A1 (en) 2004-06-02
JP4559074B2 (ja) 2010-10-06
US20040191794A1 (en) 2004-09-30
EP1423541B1 (en) 2006-07-19
EP1288308A1 (en) 2003-03-05
BR0212265B1 (pt) 2013-11-19
MXPA04001730A (es) 2004-05-31
DE60213256T2 (de) 2007-06-14
DK1423541T3 (da) 2006-10-30
JP2005501564A (ja) 2005-01-20
DE60213256D1 (de) 2006-08-31
ATE333522T1 (de) 2006-08-15
BR0212265A (pt) 2004-10-19
AU2002361779B2 (en) 2007-01-25

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