CN1565695A - Method for producing nanometer particles of plant, traditional Chinese medicine, chemical prescriptions, biological prescriptions - Google Patents
Method for producing nanometer particles of plant, traditional Chinese medicine, chemical prescriptions, biological prescriptions Download PDFInfo
- Publication number
- CN1565695A CN1565695A CN 03137342 CN03137342A CN1565695A CN 1565695 A CN1565695 A CN 1565695A CN 03137342 CN03137342 CN 03137342 CN 03137342 A CN03137342 A CN 03137342A CN 1565695 A CN1565695 A CN 1565695A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- plant
- microwave
- chemicals
- grade powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Medicinal Preparation (AREA)
Abstract
A technological process for producing powdered nano particle of plant, traditional medicine, chemical and biological preparation comprises the following steps: (1) selecting raw materials; (2) purifying; (3) adding solvent at normal temperature in microwave broken-wall extracting apparatus, microwave shaking, extracting for more than one hour; (4) filtering materials after microwave extraction; (5) concentrating after filtering; (6) five-step atomizing using a nano jet atomizer after concentrating with each step jetting speed of more than 800 m/s, finally, jetting from a jet nozzle, and drying to nano powder. The temperature is below 50 degree in the whole process.
Description
Technical field
The present invention relates to the manufacturing technique method of a kind of plant, chemicals, biologic product nanometer grade powder particulate.
Background technology
Nanometer technology is the front line science of 21st century, basic research is risen, but it is very wide as its application of nanometer new material, mainly be the skin effect and the characteristic of applying nano new material, make it improve to some extent and improve in conjunction with the original function of each product, even new to some extent discovery and profound application.At present, the nano-scale product that on market, does not also have plant, Chinese medicine, chemicals, biologic product, its reason is, want plant, Effective Components of Chinese Herb, active component, reach chemicals, biologic product purification, be reprocessed into nano-scale product, its difficulty is very big, needs a whole set of production and processing technology, and special-purpose manufacturing and processing equipment.
Summary of the invention
The manufacturing technique method that the purpose of this invention is to provide a kind of plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate.This method cooperates special-purpose manufacturing and processing equipment, and whole technology controlling and process is below 50 ℃, and this method yield height, cost is low, the time is short, and product reaches nanoscale.
For achieving the above object, the present invention takes following technical scheme:
The manufacturing technique method of a kind of plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate, this method comprises the steps:
(1), choosing plant or Chinese medicine or chemicals or biologic product is raw material;
(2), plant or Chinese medicine material are purified;
(3), plant or Chinese medicine material after will purifying, perhaps chemicals or biologic product add that solvent carries out microwave oscillation at normal temperatures, extraction is no less than 1 hour in microwave wall-breaking abstraction equipment;
(4), the material behind the microwave abstracting is filtered;
(5), the liquid after will filtering concentrates according to the method for routine, is condensed into concentrate:
(6), the concentrate after will concentrating adopts nanometer jet atomization device, atomizes by Pyatyi under normal temperature condition, and every grade of spray velocity all＞800 meter per seconds, at last, jet orifice ejection from the jet nozzle, be dried to nanometer grade powder, promptly make plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate.
In described step (6), used nanometer jet atomization device is a PN100T nanoparticle drying equipment, in this equipment, be provided with two high pressure gas pipelines and a feed tube, these two high pressure gas pipelines connect five high-pressure air pipes altogether, again by five high-pressure air pipe tap jet nozzles, described Pyatyi atomizing is that concentrate is brought in the jet spray chamber by high pressure draught by feed tube, carries out described Pyatyi atomizing.
In described step (3), used microwave wall-breaking abstraction equipment is PN microwave wall-breaking abstraction equipment, and its extracting power is: 1000L/500L; Its microwave power is: 20KW/10KW, it is to adopt unique microwave generator, microwave sky money, microwave emission and microwave receiving in the incorporate dynamic apparatus of extraction.Make extract broken wall under microwave oscillation, microwave penetration effect ooze out its biologically active and radioactivity functional component.This equipment extraction time is short, extracting power is strong, can make full use of the resource of plant, chemicals, biologic product.
In described step (3), used solvent is the ethanol of water or 50%-90%.
In described step (6), made plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate adopt vacuum-packed.
In described each step, all carry out at normal temperatures, described normal temperature is 15-50 ℃.
By said method, plant, Chinese medicine, chemicals, biologic product are processed into active ingredient, active component, the original and the compound preparation thereof that particle diameter reaches the nano molecular level obtain nanometer plant, Chinese medicine, chemicals, biologic product.The raw material that can adopt has gynostemma pentaphylla, Radix Glycyrrhizae, propolis, ginkgo leaf, compound medicine or the like.The advantage of product of the present invention is:
1, curative effect improves: the Chinese medicine of nano_scale particle is than the product of its plain particles, and surprising variation has taken place for its physicochemical property and curative effect, the Chinese medicine of some nano_scale particle even the disease that can cure difficult and complicated cases.
2, target is strong: the Chinese medicine of nano_scale particle has very strong targeting after the administration of human lumen district.
3, be used for the percutaneous dosing novel form: the Chinese medicine of nano_scale particle can reach 100% (the Transdermal absorption young people of conventional medicament reaches about 50% being used for Transdermal absorption on the method for administration, the elderly reaches about 20%), solve enzyme hydrolysis in acid degradation in the stomach, the stomach and intestine, penetrated gastrointestinal mucosa and liver first-pass effect four major problem.
4, have molecular cell affinity: the Chinese medicine and the cancer cell of nano_scale particle have affinity, can penetrate cancer cell and reach and press down cancer and anticancer.
5, middle pharmaceutically active ingredient embedding, instant capacity, permeability and the good airproof performance of nano_scale particle, but long preservation has guaranteed not react mutually characteristic such as non-volatile.
6, the intrinsic characteristic of the Chinese medicine of nano_scale particle can't penetrate bacterium, so this product belongs to sterile product.
7, the Chinese medicine of nano_scale particle kills virocyte so it can directly enter virocyte inside because of the length of length less than virocyte.
8 compare with the product of plain particles, breakthrough with energy level: the Chinese medicine of nano_scale particle is because plant cell wall breaking makes the natural energy of plant be released to human body flesh energy, under 12 kinds of elementary particles interact, form aseptic antigen, fundamentally solved the problems such as solubility property, toxic and side effect, bioavilability of traditional Chinese medicine preparation method.
9, the cosmetics of nano_scale particle can improve cosmetic result by percutaneous absorbability efficiently.
10, the biologic product of nano_scale particle can and be prepared into powdery particles with unsettled liquid active component embedding, makes its biologically active long preservation.
The advantage of manufacturing technique method of the present invention is:
1. distinctive microwave extraction process, its characteristics are fast for extracting thoroughly, keep biologically active, the rate of extraction of plant and Chinese medicine compound prescription.Chinese herbal medicine extraction time shortens to 1 hour from more than 20 hour of existing technology, and the active ingredient of extract increases by 8～10% simultaneously.
2. Du Te supersonic jet technology, its characteristics are that spray velocity fast (＞800 meter per second), spray particle diameter are little, reach nanoscale, are the 1-200 nanometer.
3. distinctive low temperature spray drying technology; be characterized in keeping the biologically active of single medicinal material and herbal mixture, can not added the wall material and directly spray, also can control the moulding requirement of micro-capsule; the micronize and the spray-drying of product are finished synchronously, be applicable to the needs of batch process.
4. distinctive equipment design, its strong innovation is compared with the existing equipment design as supersonic jet device and microwave extracter and to be had brand-new, unique, intelligentized innovation.
In a word, method of the present invention cooperates special-purpose manufacturing and processing equipment, and whole technology controlling and process is below 50 ℃, and this method yield height, cost is low, the time is short, and product reaches nanoscale.Utilize method of the present invention can also prepare the Chinese medicine novel form: as the saturating sheet absorbent of nanometer, traditional Chinese medicine powder injection, spray, paste, oral liquid etc.
Description of drawings
Fig. 1 is the technological process of production figure of plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate
Fig. 2 amplifies 30,000 times for the negative staining electron microscope photo (lot number is respectively 990209) of the nanometer grade powder particulate of gynostemma pentaphylla
Fig. 3 amplifies 150,000 times for the negative staining electron microscope photo (lot number is respectively 990209) of the nanometer grade powder particulate of gynostemma pentaphylla
Fig. 4 amplifies 50,000 times for the negative staining electron microscope photo (lot number is respectively 990917) of the nanometer grade powder particulate of gynostemma pentaphylla
Fig. 5 amplifies 100,000 times for the negative staining electron microscope photo (lot number is respectively 991226) of the nanometer grade powder particulate of gynostemma pentaphylla
Fig. 6 be the nanometer grade powder particulate of hay photo 1 (particulate pattern 100,000X)
Fig. 7 be the nanometer grade powder particulate of hay photo 2 (particulate pattern 100,000X)
Fig. 8 be the nanometer grade powder particulate of hay photo 3 (particulate pattern 100,000X)
Fig. 9 be the nanometer grade powder particulate of hay photo 4 (particulate pattern 140,000X)
Figure 10 for the treatment cardiopathic polypharmaceutic nanometer grade powder particulate photo 1 (particulate pattern 100,000X)
Figure 11 for the treatment cardiopathic polypharmaceutic nanometer grade powder particulate photo 2 (particulate pattern 100,000X)
Figure 12 for the treatment cardiopathic polypharmaceutic nanometer grade powder particulate photo 3 (particulate pattern 100,000X)
Figure 13 for the treatment cardiopathic polypharmaceutic nanometer grade powder particulate photo 4 (particulate pattern 140,000X)
The specific embodiment
Embodiment 1
The manufacturing technique method of the nanometer grade powder particulate of gynostemma pentaphylla
As shown in Figure 1, getting gynostemma pentaphylla is raw material, and gynostemma pentaphylla is cleaned the back, dries; Put into PN microwave wall-breaking abstraction equipment then, the ethanol of adding 60% adopts PN microwave wall-breaking abstraction equipment as solvent, and its extracting power is: 1000L/500L; Its microwave power is: 20KW/10KW, carry out microwave oscillation, extraction 1 hour at normal temperatures; Again the material behind the microwave abstracting is filtered; Liquid after will filtering then concentrates according to the method for routine, is condensed into concentrate; Concentrate after will concentrating at last adopts PN100T nanoparticle drying equipment, in this equipment, be provided with two high pressure gas pipelines, with a feed tube, these two high pressure gas pipelines connect five high-pressure air pipes altogether, and again by five high-pressure air pipe tap jet nozzles, described Pyatyi atomizing is, concentrate is brought in the jet spray chamber by high pressure draught by feed tube, carries out described Pyatyi atomizing.At last, the jet orifice from the jet nozzle sprays.Under normal temperature condition by Pyatyi atomizing, and every grade of equal 850 meter per seconds of spray velocity, be dried to nanometer grade powder, promptly make gynostemma pentaphylla nanometer grade powder particulate, resulting product is carried out vacuum packaging.Three batches of products of Experiment Preparation, randomly draw the sample in three batches, lot number is respectively 990209,990917,991226, and is tested by The Fourth Military Medical University, The Fourth Military Medical University's survey report (1) is as follows, and the photo of the Electronic Speculum of being taken during check is seen Fig. 2, Fig. 3, Fig. 4, Fig. 5.
The Fourth Military Medical University's survey report (1)
One, experiment purpose
Check microcapsules plant concentrates the particle size and the distribution of particulate, observes the morphological feature that the microcapsules plant concentrates particulate.
Two, experiment material and method
1, material: the plant that contains gynostemma pentaphylla concentrates the particulate microcapsules.Co., Ltd provides by the good flourish plant development new technologies in Xi'an, gets three batch samples, and lot number is respectively 990209,990917, and 991226.By forming by the emulsification and the low temperature drying of supersonic speed spraying negative pressure of gynostemma pentaphylla through microwave low-temperature extraction, low-temperature negative-pressure distillation, extract.Disperse sample concentration 1% before the experiment with DDW.
2, detection method: adopt transmission electron microscope, ammonium molybdate negative staining, multiplication factor 20,000-150,000 times.100 particulates of each sample determination according to the Principle of Statistics pin analysis of uniting, are obtained the average grain diameter size of particulate and are distributed.Instrument JEM-2000 electron microscope.
Three, experimental result
The plant that contains gynostemma pentaphylla concentrates particulate microcapsules average grain diameter and is respectively 87 ± 45nm, 92 ± 37nm and 75 ± 53nm, is the nanoscale microcapsules.
Four, conclusion
It is the nanoscale microcapsules that the plant that contains gynostemma pentaphylla that is produced by the good flourish plant development new technologies in Xi'an Co., Ltd concentrates the particulate microcapsules.
By The Fourth Military Medical University's survey report (1) and Fig. 2-Fig. 5, prove and adopt method and apparatus of the present invention that the nanometer grade powder particulate of preparation gynostemma pentaphylla all can reach nano_scale particle.
Embodiment 2
The manufacturing technique method of the nanometer grade powder particulate of hay
Except that taking raw material was hay, remaining was all identical with embodiment 1.The a collection of product of Experiment Preparation is randomly drawed the sample in a collection of, and is tested by Xi'an Communications University, and Xi'an Communications University's transmission electron microscope laboratory report (1) is as follows, and the photo of the Electronic Speculum of being taken during check is seen Fig. 6, Fig. 7, Fig. 8, Fig. 9.
Xi'an Communications University's transmission electron microscope laboratory report (1)
One. client:
Xi'an good flourish plant development new technologies Co., Ltd
Two, experiment purpose:
Plant concentrates the particle size of particulate and observes its morphological feature the check micro-capsule.
Three, experiment material and method:
The concentrated particulate samples of plant that contains Radix Glycyrrhizae is a collection of.This sample is disperseed with DDW; Sample concentration 1-2%.Be prepared into sample for use in transmitted electron microscope with the ammonium molybdate negative staining then, use Japanese JEM-200CX transmission electron microscope to amplify 100,000-140,000 times and observe.
Four, experimental result:
Observed result is seen photo 1-4 (seeing attached sheet) (being accompanying drawing 6-9), and mean particle dia is 19 ± 11nm, is nano_scale particle.
By Xi'an Communications University's transmission electron microscope laboratory report (1) and Fig. 6-Fig. 9, prove and adopt method and apparatus of the present invention that the nanometer grade powder particulate of preparation hay all can reach nano_scale particle.
Embodiment 3
Treat the manufacturing technique method of cardiopathic polypharmaceutic nanometer grade powder particulate
Except that taking raw material difference, remaining is all identical with embodiment 1.The a collection of product of Experiment Preparation is randomly drawed the sample in a collection of, and is tested by Xi'an Communications University, and Xi'an Communications University's survey report (2) is as follows, and the photo of the Electronic Speculum of being taken during check is seen Figure 10, Figure 11, Figure 12, Figure 13.
Xi'an Communications University's transmission electron microscope laboratory report (2)
One, client:
Xi'an good flourish plant development new technologies Co., Ltd
Two, experiment purpose:
Plant concentrates the particle size of particulate and observes its morphological feature the check micro-capsule.
Three, experiment material section and method:
The sample of the concentrated particulate of the plant of Kang Erxin is a collection of.This sample is disperseed with distilled water; Sample concentration 1-2% is prepared into sample for use in transmitted electron microscope with the ammonium molybdate negative staining then, uses Japanese JEM-200CX transmission electron microscope to amplify 100,000 times-140,000 times and observes.
Four, experimental result:
Observed result is seen photo 1-4 (seeing attached sheet) (being accompanying drawing 10-13).Mean particle dia is 34 ± 26nm, is nano_scale particle.
By Xi'an Communications University's transmission electron microscope laboratory report (2) and Figure 10-Figure 13, prove and adopt method and apparatus of the present invention that the cardiopathic polypharmaceutic nanometer grade powder particulate of preparation treatment all can reach nano_scale particle.Annotate: " Kang Erxin " in Xi'an Communications University's transmission electron microscope laboratory report (2) is " treating cardiopathic compound medicine ".
Embodiment 4
The manufacturing technique method of the nanometer grade powder particulate of propolis
Except that taking raw material difference, remaining is all identical with embodiment 1.The nanometer grade powder particulate of preparation propolis all can reach nano_scale particle
Propolis is rich in protein, amino acid, multivitamin, macroelement, dimension secondary element, various active enzyme, organic acid, auxin and flavone compound.Have and promote body growth, the effect of building up resistance; The effect that also has defaecation detoxifcation, beautifying and anti-aging.Being the Gospel of diabetes patient and cancer, also is Mrs youth cosmetic good merchantable brand.But because common propolis is water insoluble, human body is difficult to absorb, so in fact common propolis is difficult to reach above-mentioned curative effect.The nanometer grade powder particulate of the propolis of producing through manufacturing technique method of the present invention can all be dissolved in the water, and it is water insoluble to have solved propolis, and the difficult problem that human body is difficult to absorb has strengthened the effect of propolis.
Claims (6)
1, the manufacturing technique method of a kind of plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate, it is characterized in that: this method comprises the steps:
(1), choosing plant or Chinese medicine or chemicals or biologic product is raw material;
(2), plant or Chinese medicine material are purified;
(3), plant or Chinese medicine material after will purifying, perhaps chemicals or biologic product add that solvent carries out microwave oscillation at normal temperatures, extraction is no less than 1 hour in microwave wall-breaking abstraction equipment;
(4), the material behind the microwave abstracting is filtered;
(5), the liquid after will filtering concentrates according to the method for routine, is condensed into concentrate;
(6), the concentrate after will concentrating adopts nanometer jet atomization device, atomizes by Pyatyi under normal temperature condition, and every grade of spray velocity all＞800 meter per seconds, at last, jet orifice ejection from the jet nozzle, be dried to nanometer grade powder, promptly make plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate.
2, plant according to claim 1, Chinese medicine, chemicals, the manufacturing technique method of biologic product nanometer grade powder particulate, it is characterized in that: in described step (6), used nanometer jet atomization device is a PN100T nanoparticle drying equipment, in this equipment, be provided with two high pressure gas pipelines, with a feed tube, these two high pressure gas pipelines connect five high-pressure air pipes altogether, again by five high-pressure air pipe tap jet nozzles, described Pyatyi atomizing is that concentrate is brought in the jet spray chamber by high pressure draught by feed tube, carries out described Pyatyi atomizing.
3, the manufacturing technique method of plant according to claim 1 and 2, Chinese medicine, chemicals, biologic product nanometer grade powder particulate, it is characterized in that: in described step (3), used microwave wall-breaking abstraction equipment is PN microwave wall-breaking abstraction equipment, and its extracting power is: 1000L/500L; Its microwave power is: 20KW/10KW, it is to adopt unique microwave generator, microwave sky money, microwave emission and microwave receiving in the incorporate dynamic apparatus of extraction.
4, the manufacturing technique method of plant according to claim 3, Chinese medicine, chemicals, biologic product nanometer grade powder particulate is characterized in that: in described step (3), used solvent is the ethanol of water or 50%-90%.
5, the manufacturing technique method of plant according to claim 4, Chinese medicine, chemicals, biologic product nanometer grade powder particulate, it is characterized in that: in described step (6), made plant, Chinese medicine, chemicals, biologic product nanometer grade powder particulate adopt vacuum-packed.
6, the manufacturing technique method of plant according to claim 5, Chinese medicine, chemicals, biologic product nanometer grade powder particulate is characterized in that: in described each step, all carry out at normal temperatures, described normal temperature is 15-50 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03137342 CN1565695A (en) | 2003-06-18 | 2003-06-18 | Method for producing nanometer particles of plant, traditional Chinese medicine, chemical prescriptions, biological prescriptions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03137342 CN1565695A (en) | 2003-06-18 | 2003-06-18 | Method for producing nanometer particles of plant, traditional Chinese medicine, chemical prescriptions, biological prescriptions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1565695A true CN1565695A (en) | 2005-01-19 |
Family
ID=34470366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03137342 Pending CN1565695A (en) | 2003-06-18 | 2003-06-18 | Method for producing nanometer particles of plant, traditional Chinese medicine, chemical prescriptions, biological prescriptions |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1565695A (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1785153B (en) * | 2005-12-06 | 2010-04-21 | 青岛大学 | Nano-grade material preparation apparatus, and method for preparing nano-anti-oxidation active poly peptide medicine |
| CN101991034A (en) * | 2010-11-11 | 2011-03-30 | 周云川 | High-efficiency wall breaking propolis soft capsule |
| CN107224748A (en) * | 2016-03-24 | 2017-10-03 | 卢奕祥 | A kind of pigment collection device |
| CN111110759A (en) * | 2018-11-01 | 2020-05-08 | 北京中西联盟肿瘤医学研究院(普通合伙) | Water-eliminating ointment for treating cancerous ascites and preparation method thereof |
| CN111110785A (en) * | 2018-11-01 | 2020-05-08 | 北京中西联盟肿瘤医学研究院(普通合伙) | Carbuncle block eliminating ointment for treating cancer pain and preparation method thereof |
| CN111110775A (en) * | 2018-11-01 | 2020-05-08 | 北京中西联盟肿瘤医学研究院(普通合伙) | A Chinese medicinal ointment for treating cancerous abdominal distention, and its preparation method |
| CN111991840A (en) * | 2020-08-26 | 2020-11-27 | 恒天(厦门)健康产业发展有限公司 | Process for preparing nano Chinese medicine |
| CN112076496A (en) * | 2020-09-25 | 2020-12-15 | 炁艾生命科技(深圳)有限公司 | Intelligent traditional Chinese medicine extraction machine |
| CN116440002A (en) * | 2023-06-16 | 2023-07-18 | 云南艾柯生物科技有限公司 | Rhinitis spray preparation method based on traditional Chinese medicine composition |
-
2003
- 2003-06-18 CN CN 03137342 patent/CN1565695A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1785153B (en) * | 2005-12-06 | 2010-04-21 | 青岛大学 | Nano-grade material preparation apparatus, and method for preparing nano-anti-oxidation active poly peptide medicine |
| CN101991034A (en) * | 2010-11-11 | 2011-03-30 | 周云川 | High-efficiency wall breaking propolis soft capsule |
| CN101991034B (en) * | 2010-11-11 | 2012-11-14 | 周云川 | High-efficiency wall breaking propolis soft capsule |
| CN107224748A (en) * | 2016-03-24 | 2017-10-03 | 卢奕祥 | A kind of pigment collection device |
| CN111110759A (en) * | 2018-11-01 | 2020-05-08 | 北京中西联盟肿瘤医学研究院(普通合伙) | Water-eliminating ointment for treating cancerous ascites and preparation method thereof |
| CN111110785A (en) * | 2018-11-01 | 2020-05-08 | 北京中西联盟肿瘤医学研究院(普通合伙) | Carbuncle block eliminating ointment for treating cancer pain and preparation method thereof |
| CN111110775A (en) * | 2018-11-01 | 2020-05-08 | 北京中西联盟肿瘤医学研究院(普通合伙) | A Chinese medicinal ointment for treating cancerous abdominal distention, and its preparation method |
| CN111991840A (en) * | 2020-08-26 | 2020-11-27 | 恒天(厦门)健康产业发展有限公司 | Process for preparing nano Chinese medicine |
| CN112076496A (en) * | 2020-09-25 | 2020-12-15 | 炁艾生命科技(深圳)有限公司 | Intelligent traditional Chinese medicine extraction machine |
| CN112076496B (en) * | 2020-09-25 | 2021-05-14 | 炁艾生命科技(深圳)有限公司 | Intelligent traditional Chinese medicine extraction machine |
| CN116440002A (en) * | 2023-06-16 | 2023-07-18 | 云南艾柯生物科技有限公司 | Rhinitis spray preparation method based on traditional Chinese medicine composition |
| CN116440002B (en) * | 2023-06-16 | 2023-09-15 | 云南艾柯生物科技有限公司 | Rhinitis spray preparation method based on traditional Chinese medicine composition |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1565695A (en) | Method for producing nanometer particles of plant, traditional Chinese medicine, chemical prescriptions, biological prescriptions | |
| CN1253152C (en) | Single particle nano-garlicin micro-capsule, and its prepn. method | |
| CN1360916A (en) | Nanometer zhangyanming medicine for treating eye disease and its prepn | |
| CN1366936A (en) | Nano antelope lung-clearing preparation medicine and preparation method | |
| CN1368292A (en) | Nano medicing 'Wenzhong Zhixie' and its preparing process | |
| CN1360931A (en) | Nanometer luminous Dendrobium nobil medicine and its prepn | |
| CN1368235A (en) | Nano medicine for treating leukoderma and its preparing process | |
| CN1368151A (en) | Nano medicine 'Hailong Gejie' and its preparing process | |
| CN1364486A (en) | Nano ten ingredient restoration medicine and its preparing method | |
| CN1660202A (en) | Nano medical preparation for promoting blood circulation and preparation method | |
| CN1534285A (en) | Head flower knotweed and its extract and product bioactivity measuring method | |
| CN1368318A (en) | Nano medicine 'Shugantiaoqi' and its preparing process | |
| CN1368263A (en) | Nano medicine for treating infantile intractable cough and its preparing process | |
| CN1360939A (en) | Nanometer eyesight-improving and health-clearing medicine and its prepn | |
| CN1368177A (en) | Nano medicine 'Shangshiqutong' and its preparing process | |
| CN1368252A (en) | Nano medicine 'Banfenghe' and its preparing process | |
| CN1363307A (en) | Nano medicine 'Guiluningshen' and its preparing process | |
| CN1366977A (en) | Nano Guloushan dieda preparation medicine and preparation method | |
| CN1365695A (en) | Nano medicine 'Xiaoer Jindan' and its preparing process | |
| CN1368357A (en) | Nano medicine 'Weitongding' and its preparing process | |
| CN1365685A (en) | Nano medicine for reating bone fracture and injury and its preparing process | |
| CN1368145A (en) | Nano medicine 'Gengnianshu' and its preparing process | |
| CN1368361A (en) | Nano medicine 'Xiaoer Jingan' and its preparing process | |
| CN1364530A (en) | Nano kidney tnfiying and brain invigorating medicine and its preparing method | |
| CN1513486A (en) | Liver-care composition and its prepn. method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |