CN1552437A - Use of Jinshuibao capsule in preparing medicine for treating AIDS - Google Patents
Use of Jinshuibao capsule in preparing medicine for treating AIDS Download PDFInfo
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- CN1552437A CN1552437A CNA031408869A CN03140886A CN1552437A CN 1552437 A CN1552437 A CN 1552437A CN A031408869 A CNA031408869 A CN A031408869A CN 03140886 A CN03140886 A CN 03140886A CN 1552437 A CN1552437 A CN 1552437A
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- aids
- jinshuibao
- treating aids
- preparing medicine
- medicine
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Abstract
A Chinese medicine 'Jinshuibao capsule' for treating AIDS and improving immunity is prepared from artificial cordyceps powder.
Description
The present invention relates to the application of a kind of paecilomyces hepiall chen in the medicine of preparation treatment acquired immune deficiency syndrome (AIDS).
Paecilomyces hepiall chen is the fermented Cordyceps powder (C that Jiangxi Jinshuibao Pharmaceutical Co., Ltd. adopts the modern biotechnology preparation
S-4), be the natural cs succedaneum, be approved for the new Chinese medicine of a national class, lot number: (89) are defended the accurate word Z-18 of medicine number.It is that Cordyceps-peacilomyce hepiahi (Paecilomyces hepiali chen) Cs-4 bacterial strain separating obtained the fresh Cordyceps [Cordyceps sinensis (Berk.) Sacc.] is produced in a kind of employing from Qinghai, purified, artificial fermentation is cultivated, process-its character of c-is an extremely shallow chocolate brown powder of yellowish-brown, and special fragranced is arranged.Studies have shown that through units such as institute of Materia Medica,Chinese Academy of Medical Sciences, it is similar that the natural cs composition is produced in its chemical analysis and Qinghai, contains element and vitamin Bs such as 19 seed amino acids such as ribosidoadenine, uracil nucleoside, mannitol, ergosterol and aspartic acid, glutamic acid, threonine, glycine, lysine, serine, alanine, leucine, proline and zinc, potassium, manganese, phosphorus, selenium
1, vitamin B
2, multiple composition such as vitamin E.Prove that through pharmacological evaluation this product has antiinflammatory, cough-relieving, eliminates the phlegm, calm, short gonad effect.Can reduce serum cholesterol, triglyceride and lipid peroxide increase the blood supply of cardiac muscle and brain; have slightly and bring high blood pressure down, anticoagulant, effect such as survival time of animals when prolonging anoxia; heart and brain tissues is had protective effect, and its main pharmacological is similar to the Qinghai natural cs.Have nourishing lung and kidney, the secret lean qigong is imitated, the clinical deficiency of both the lung and kidney that is used for, vital essence deficiency, chronic cough dyspnea due to deficiency, spiritlessness and weakness, insomnia and amnesia, soreness of the waist and knees, menoxenia, diseases such as impotence and premature ejaculation; And chronic bronchitis, chronic renal insufficiency, hyperlipemia, liver cirrhosis are seen above-mentioned patient.Do not see at present the clinical report that is used for acquired immune deficiency syndrome (AIDS).
The object of the present invention is to provide the application of a kind of paecilomyces hepiall chen in the medicine of preparation treatment acquired immune deficiency syndrome (AIDS).
The present invention is by the application of every dress Cordyceps powder 0.16g-0.33g paecilomyces hepiall chen in the medicine of preparation treatment acquired immune deficiency syndrome (AIDS).Pharmaceutical research shows, JINSHUIBAO has following pharmacological action: (1) is to the influence of spleen, thymic weight and reticuloendothelial system: JINSHUIBAO abdominal cavity or subcutaneous injection can be accelerated colloid carbon clearance speed in the mice blood, strengthen the peritoneal macrophage phagocytic activity, increase liver, spleen weight, and can resist the spleen that cyclophosphamide and prednisone cause and heavily alleviate.(2) influence of pair cell immunologic function and humoral immune function: JINSHUIBAO is that 5～10mg/ml is external with concentration has slight stimulation to thymus and splenocyte; can promote tardy anaphylaxis and immune organ protective effect; and the mice serum hemolysin is generated, serum IgG increases.Therefore, to immunologic function, particularly the influence to specific immune function belongs to two-ways regulation.Internal and external test proves, water extract (500mg/ml contains crude drug) can improve normal person and leukaemic NK cytoactive, and in institute's using dosage scope (1.56～25mg/ml), be the dosage effect dependency.Find simultaneously, can promote the antigenic expression of lymphocytic cell surface CD16, improve the combination rate of K562 cell, and,, the treatment meaning is arranged so can improve leukemia people's NK cytoactive to the leukocyte free of toxic effects.In addition, clinically treated 27 routine acquired immune deficiency syndrome (AIDS) patients 3 months, measure the incidence rate of cd4 cell number and CD4/CD8 ratio and upper respiratory tract infection with monoclonal antibody reagent with paecilomyces hepiall chen.The result: 7 routine immunologic functions take a turn for the better, obvious effective rate 27% (10/27), and total effective rate 70% (19/27), the incidence rate of upper respiratory tract infection reduces by 31%.Conclusion: paecilomyces hepiall chen can obviously improve acquired immune deficiency syndrome (AIDS) patient's immunity, reduces the incidence rate of upper respiratory tract infection, treats the acquired immune deficiency syndrome (AIDS) patient effectively.
The invention has the advantages that: improve the immunity of aids patient, reduce the incidence rate of upper respiratory tract infection, do not see obvious toxic-side effects.
With specific embodiment the present invention is elaborated below:
Every dress of paecilomyces hepiall chen Cordyceps powder 0.16g-0.33g, oral, a 3-6 grain, 3 times on the one, 3 months is 1 course of treatment.Can obviously improve the immunity of aids patient, reduce the incidence rate of upper respiratory tract infection, treat the acquired immune deficiency syndrome (AIDS) patient effectively.
Claims (1)
1. the application of paecilomyces hepiall chen in the medicine of preparation treatment acquired immune deficiency syndrome (AIDS), paecilomyces hepiall chen are to be made by every dress Cordyceps powder 0.16g-0.33g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031408869A CN1552437A (en) | 2003-06-05 | 2003-06-05 | Use of Jinshuibao capsule in preparing medicine for treating AIDS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031408869A CN1552437A (en) | 2003-06-05 | 2003-06-05 | Use of Jinshuibao capsule in preparing medicine for treating AIDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1552437A true CN1552437A (en) | 2004-12-08 |
Family
ID=34323923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031408869A Pending CN1552437A (en) | 2003-06-05 | 2003-06-05 | Use of Jinshuibao capsule in preparing medicine for treating AIDS |
Country Status (1)
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| CN (1) | CN1552437A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991614A (en) * | 2010-09-13 | 2011-03-30 | 吴赣英 | Compound fermented cordyceps sinensis powder (paecilomyces hepiali Cs-4 bacterial powder) combined medicine and preparation thereof |
| WO2015100579A1 (en) * | 2013-12-31 | 2015-07-09 | 王忠林 | Pharmaceutical composition for treating acquired immune deficiency syndrome and method for preparing same |
| US20150265664A1 (en) * | 2012-09-13 | 2015-09-24 | Jiangzhong Pharmaceutical Co., Ltd. | Traditional chinese medicine combination for regulating immune function and preparation method therefor |
| CN106138163A (en) * | 2016-07-29 | 2016-11-23 | 桂林淮安天然保健品开发有限公司 | A kind of pharmaceutical composition treating acquired immune deficiency syndrome (AIDS) |
-
2003
- 2003-06-05 CN CNA031408869A patent/CN1552437A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991614A (en) * | 2010-09-13 | 2011-03-30 | 吴赣英 | Compound fermented cordyceps sinensis powder (paecilomyces hepiali Cs-4 bacterial powder) combined medicine and preparation thereof |
| US20150265664A1 (en) * | 2012-09-13 | 2015-09-24 | Jiangzhong Pharmaceutical Co., Ltd. | Traditional chinese medicine combination for regulating immune function and preparation method therefor |
| US9775868B2 (en) * | 2012-09-13 | 2017-10-03 | Jiangzhong Pharmaceutical Co., Ltd. | Traditional Chinese medicine combination for regulating immune function and preparation method therefor |
| WO2015100579A1 (en) * | 2013-12-31 | 2015-07-09 | 王忠林 | Pharmaceutical composition for treating acquired immune deficiency syndrome and method for preparing same |
| US9623053B2 (en) | 2013-12-31 | 2017-04-18 | Zhonglin Wang | Pharmaceutical composition for treating AIDS and preparation method thereof |
| CN106138163A (en) * | 2016-07-29 | 2016-11-23 | 桂林淮安天然保健品开发有限公司 | A kind of pharmaceutical composition treating acquired immune deficiency syndrome (AIDS) |
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| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |