CN1169315A - Immunity-regulating health-care tea - Google Patents
Immunity-regulating health-care tea Download PDFInfo
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Abstract
The health-care tea for preventing and treating immunity diseases is prepared by using wilsonii, the fruit of Chinese wolfberry, the fruit of glossy privet, the fruit of Chinese magnoliavine, longspur epimedium, Gynostemma pentaphylla, the root of membranous milk vetch, Fuling, the tube of dwarf lilyturf long-noded pit viper snakeweed, Chinese date adn green tee leaves as raw material through the process of frizzing or airing to dry, mixing according to a certain proportion, then efflorescing and sterilizing to make powder preparation. Said product has the advantages of scientific formula and positive effect etc..
Description
The present invention relates to the affiliated immune disease of a kind of adjusting immunizing health tea control.The example: malignant tumor, viral hepatitis, regular flu, lose hair, dermatosis, as urticaria, eczema etc.And can prolong some cell survival, slow down aging, life lengthening.Specifically be the Chinese patent medicine of feedstock production with the Chinese herbal medicine, " pouring type tea bag ".
Malignant tumor is the common frdquently encountered disease of serious harm human health.The cancer patient is about 1,400 ten thousand in the world, and world New Development cancer patient 7,500,000 is dead 5,000,000, and China about 1,500,000, dead 1,100,000 also has and increases trend gradually, is first formidable enemy who jeopardizes the human life.
Malignant tumor is not allowed to cure, and pathogenic factor is different, but many and immunodeficiency is closely related.In individuality took place, immune function changed with the age.General is low in birth, increases to peak very soon, increases with the age later on to descend.And the tumor incidence rate of all ages and classes changes relevant with immune function.T cell mediated immune surveillance mechanism has the effect that suppresses carcinogenesis.In this mechanism, if the T cellular machine can be given full play to, then the mutant that occurs in the body is difficult to be discerned, get rid of, make and can escape immunosurveillance and carcinogenic by the host.
Clinical discovery: immunodeficiency merges cancer more, and it is unusual that its reason is still immune mechanism.Yet not only the T cellular abnormality can be suffered from tumor, and the B cellular abnormality also can make carcinogenic rate increase.
The carcinogenic hidden danger of immunodeficiency is more, and the Cheng Du that the indication tumor recurrence shifts is bigger.Activating or strengthening nonspecific immunity to make the carcinogenesis rate reduce.Therefore immunodeficiency is perfect with immunity, to the deterioration of tumor with improve most important.Improving in clinical immunity is the instinct rule of treatment.Prove in recent years in the tumor recurrence case, have CEA immune complex (immune compiex) in the blood, the CEA-IC immune complex is an evidence of tumor metastasis.The formation of this immune complex, many because due to the generation of autoimmune antibody.The generation of autoimmune antibody, the formation of immune complex can cause palindromia to be shifted.Be person in middle and old age go into to suffer from the common reason of tumor mortality.
Viral hepatitis also is the common frdquently encountered disease of harm humans health.Spreading all over the world, is " hepatitis B " by it, HBsAg carrying rate Northern Europe, West Europe and North America 0.1～1.0%, and area, Asia and Africa 5～10%, China is about 10%, is a big disease that jeopardizes the human life.
Hepatitis B all the life more the route of transmission extensively (1) menses propagate (2) contact (3) perinatal transmission (4) arthropod-borne closely.The state of an illness is divided acute hepatitis, chronic hepatitis, icterohepatitis.Its pathogeny and organism immune response are closely related; Whether the weight of the state of an illness is that infected people's immunoreation determines.The HBsAg-IgM immune complex rises in the liver immunologic injury and sees important effect, and prompting HBsAg exists with the form of immune complex and anti-HBs can not bring into play its due protective immunity effect, and virus can not in time be eliminated.
Chronic hepatitis and HBV infect relevant with the immune function of human body disorder, and the HBV infection causes and immunoreation is mainly cell immune response.After HBV enters hepatocyte, virus itself is not directly damaged hepatocyte, but can change the antigenicity of surface of hepatocytes film, stimulate the T cell to produce specific cell immunoreaction, T cell differentiation breeding is primed lymphocyte, discharges multiple lymphokine, kills and wounds hepatocyte and starts an inflammation of the liver, discharge virus simultaneously, hepatic lesions is repaired subsequently.Low as immune function of human body, by cell immune response, destroy the part of hepatocytes that is infected by the virus, and can not remove virus fully, make the pathological changes protracted course of disease.
Chronic hepatitis is also relevant unusually with humoral immune reaction.Cellular immune function deficiency (comprising that the T cell suppresses cell hypofunction) and humoral immunization function deficiency (can not make lot of antibodies as the B cell) are to cause the constantly key factor of infringement of hepatocyte.
Virus is closely related with tumor, and the HBsAg of primary hepatocarcinoma patient and anti--HBc positive rate are apparently higher than the contrast crowd.The hepatocarcinoma hotspot, the incidence of hepatitis rate is also high.Hepatocarcinoma patient HBsAg positive rate is significantly higher than healthy population.For the PLC mortality rate certain contact is arranged.Hepatitis history and liver cirrhosis person are arranged, apparently higher than matched group in the hepatocarcinoma patient.The chance of hepatocarcinoma takes place in hepatitis regulating liver-QI sclerosis people, and is higher 9～10 times than matched group.HBV can cause cell transfer or bring out hepatocarcinoma.Be suffer from the common cause of hepatitis death.
Regular flu is a common frdquently encountered disease.Though there are not data to show, account for certain proportion among the crowd, be one of disease of infringement health of human body level.
Flu is divided multiple: anemofrigid cold, anemopyretic cold, influenza etc. are arranged.But the chronicity flu is very troublesome, because hypoimmunity, positive QI-insufficiency causes the ability of the low anti-exopathogen of human body to go down.Cause virus, infectant etc. to be taken advantage of a weak point.Plain body weakness, immunodeficiency; Can not defend tenaciously, make exopathogen often invade the common pathogenic factor that is harmful to health.
Lose hair also is common frdquently encountered disease.The patient every with hair washing or rise morning see on the pillow of back more and quantity more.From outside watch severe patient to impair people's appearance, also impair healthy.
Cannot not lose hair painfully and itch, difficult control.Its pathogenic factor is how relevant with the body's immunity disorder.As Metabolic disorder, malnutrition; Psychic trauma and hypertonicity etc.Under the traditional Chinese medical science " hair is the sign of blood condition is sent out and led by kidney ".It is thanks to empty mostly to be Liver and kidney, deficiency of YIN deficiency; Space between skin and muscles is solid, or because of feelings will unsuccessful; Qi-blood disharmony, sending out becomes homeless supports and comes off gradually, is the common pathogenic factor of infringement health of human body.
Dermatosis is the frequently-occurring disease of infringement health of human body.Though also the free of data statistics accounts among the crowd quite than number.
Dermatosis is of a great variety, and pathogenic factor is had nothing in common with each other.But prolonged and repeated, as not heal year in year out dermatosis, many and immunity of organism factor reacts closely related.The traditional Chinese medical science is thought: failure of defensive QI to protect the body against pathogen, interspaces of skin and muscles being loose; Feel exopathogen again, or show freely obstruction of QI because of feelings will; Deficiency of the liver and kindey, qi-blood disharmony, failure of skin and muscle to be nourished.Institute's natural fibre line of meat of heresy, its gas must be empty, and the void then skin natural fibre line of meat is opened.
Recent study proves that majority is an autoimmune disease, detects antigen-antibody in the body.HL-A antigen is relevant with psoriasis.Anti-coat of the stomach antibody, antithyroglobulin antibodies and antinuclear antibody.Confirming in the serum has melanin antibody all relevant with leukoderma.
Eczema, urticaria are resisting allergic diseases, also belong to the autoimmunity allergy.Some urticaria then is the III allergic reaction type, and the III allergic reaction type is the antigen antibody complex reaction.Antigen antibody complex produces anaphylatoxin in the activating complement process, stimulate loose cell to discharge histamine and cause urticarial generation.Eczema is the IN allergic reaction type, can form autoantigen.Urticaria is if that the larynx mucosa when being invaded, can cause is uncomfortable in chest, breathe hard, dyspnea, and severe patient can cause and suffocate and threat to life.Be suffer from the common cause of dermatological damage health of human body.
Domestic and international at present the problem that prevention faced to affiliated immune disease:
1,, removes self to improve and encircle scape (pollution, radioactivity stimulation, physics and chemical factor damage etc.) on every side to the prevention of tumor.Remove bad life habits (smoking, spirits, curing food, baked foods, food etc. goes mouldy), the report of no other medicines prevention.
2, the prevention to viral hepatitis is " Hepatitis B virus vaccine ".The prevention scope: except that school is most popularize, popularity rate is lower and price is more expensive in social crowd.It is the another extensive approach that causes virus disseminating.
3,, mostly be " gamma globulin " to the prevention of frequent flu.This product belongs to blood products, can cause exogenous antigen, and prognosis is not good.
4, the inoculation of Measles Vaccine does not all have other dermatosis and to examine property.
5, domestic and international prophylactic agent to alopecia does not still have report.
Though the health tea of some therapeutical effect is also arranged, its function is closely not similar to the present invention.Generally many with invigorating brain and relieving mental uneasiness, digesting and appetizing; Moisten hot-tempered relieving constipation, fat-reducing; Appearance such as blood fat reducing, blood pressure lowering.The single health tea that is similar to effect of the present invention is also arranged, but because effect is not fairly obvious, foot can not play should there be effect to diseases prevention and treatment.The control of immune disease do not had clearly examine, use simple property.
The object of the present invention is to provide a kind of vigor that activates reticuloendothelial system and cellular immunization and humoral immunization that has, enhancing antibody synthetic or synthetic as early as possible (a kind of protection antibody that exists in the body).Enhancing body is to non-specific anti-unload power, the resistance of various destructive stimuluses.Promote the integration effect of immune absorption, removing, inhibition, adjustment.Improve the prevention and the therapeutic agent of the immune disease of body specific immune function.
Another object of the present invention provides the preparation method of this preventing autoimmune disorder agent.
Solution of the present invention is based on motherland's medical science to pathogenetic understanding of immune disease and control principle, participates in the achievement of modern pharmacological research, filters out nourishing the liver and kidney, replenishing QI to invigorate the spleen from motherland's medicine treasure-house; Calm calming the nerves, the sterilization detoxifcation; Strengthening the body resistance is regulated the homologous natural edible plant amedica of negative and positive medicated diet.According to theory of Chinese medical science research prescription, make its performance discharge a large amount of macrophages by excited reticuloendothelial system, improve the opsonic vigor of serum.Immune antibody and sedimentary antigen nanocrystal composition are played promotion absorption and scavenging action.Can suppress the pathological lesion due to the immunoreation of antigen body, improve and recover immune from steady effect.Can directly sterilize with antibacterial to infectious disease.Reduce the permeability of blood capillary, the minimizing inflammation is oozed out and is promoted and absorbs.Improve hemorheological property, improve the conversion ratio of lymphocyte T, strengthen cellular immunization.It is hyperfunction to suppress immunologic function again.Resisting allergic diseases is reduced and the caused toxic and side effects of removing immunosuppressant, and can increase plasma C AMP content, promote humoral immunization, improve the content of immunoglobulin IgG.Can improve the immune Stabilization that is weakened, can eliminate deleterious autoimmune response again, immune system is played integrally-regulated effect.Thereby the defence of virulence factors such as infection, poisoning, radiation injury, tumor and the formation of specific immune reaction are all played an important role.The metabolism and the aging course that also participate in materials such as fat, protein, steroid also have important relationship.To immune disease particularly autoimmune disease the important meaning of control is arranged generally.Reduce, control the effect of suspicious disease development.
Medicine of the present invention is made (consumption is gram) by following component:
Radix Acanthopanacis Senticosi 0.1-0.5 gram Fructus Lycii 0.1-0.5 gram Fructus Ligustri Lucidi 0.1-0.5 gram
Fructus Schisandrae Chinensis 0.1-0.5 gram Herba Epimedii 0.1-0.5 gram Herb Gynostemmae Pentaphylli 0.1-0.5 gram
Radix Astragali 0.1-0.5 gram Poria 0.1-0.5 gram 0.1-0.5 Radix Ophiopogonis gram
Herba Hedyotidis Diffusae 0.1-0.5 gram Fructus Jujubae 0.5-2.5 gram green tea 0.5-2.5 gram
The formula optimization weight proportion scope of preparation medicine of the present invention is:
Radix Acanthopanacis Senticosi 0.2-0.4 gram Fructus Lycii 0.2-0.4 gram Fructus Ligustri Lucidi 0.2-0.4 gram
Fructus Schisandrae Chinensis 0.2-0.4 gram Herba Epimedii 0.2-0.4 gram Herb Gynostemmae Pentaphylli 0.2-0.4 gram
Radix Astragali 0.2-0.4 gram Poria 0.2-0.4 gram 0.2-0.4 Radix Ophiopogonis gram
Herba Hedyotidis Diffusae 0.2-0.4 gram Fructus Jujubae 0.5-1.5 gram green tea 0.5-1.5 gram
The best important proportioning of medicine of the present invention is:
Radix Acanthopanacis Senticosi 0.3 gram Fructus Lycii 0.3 gram Fructus Ligustri Lucidi 0.3 gram
Fructus Schisandrae Chinensis 0.3 gram Herba Epimedii 0.3 gram Herb Gynostemmae Pentaphylli 0.3 gram
The Radix Astragali 0.3 gram Poria 0.3 gram gram Radix Ophiopogonis 0.3
Herba Hedyotidis Diffusae 0.3 gram Fructus Jujubae 1 gram green tea 1 gram
Above-mentioned each component is made medicine production method of the present invention is:
1, with Fructus Lycii, Radix Ophiopogonis, processing powder was broken into 40-120 order powdery after freezing drying under-15 ℃;
2, Fructus Jujubae freezing drying under-15 ℃ is ground into 40-120 order powdery;
3, Radix Et Caulis Acanthopanacis Senticosi, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Herba Epimedii, Herb Gynostemmae Pentaphylli, the Radix Astragali, Poria, Herba Hedyotidis Diffusae are ground into 40-120 order powdery after air-dry;
4, Folium Camelliae sinensis is ground into 40-120 order powdery after air-dry;
5, with above-mentioned whole powder components in described ratio mixing after, under 40-60 ℃, carry out air slaking, sterilization treatment 10-30 minute.Can obtain preventing and treating the powder medicine of immune disease.
Powder after air slaking are handled also can be made into graininess powder, need add methods such as a little bondings or profitization mechanism this moment in right amount and handle the back drying, can obtain the powder of graininess dosage form.Be packed as the fractional pack of 3-10 gram weight.
The pharmacological action of each component of the present invention:
Radix Acanthopanacis Senticosi 1. root contains alkaloid, Saponin, volatile oil, polysaccharide, other parts and contains volatile oil.
2. the antitumor action of Radix Et Caulis Acanthopanacis Senticosi polysaccharide and immunization: quiet swimming injection high concentration Radix Et Caulis Acanthopanacis Senticosi polysaccharide 0.34g/kg is then to mice S
37.S
180Tumor has the remarkable inhibitory action (P＜0.01) of inhibition.
3. to the experimentation of T cell facilitation: Radix Et Caulis Acanthopanacis Senticosi can promote lymphocyte to the replying of PHA, but itself and no mitogen effect.Radix Et Caulis Acanthopanacis Senticosi is to work by the signal that amplifies or reduce cell acceptance, can promote the effect that PHA replys by stoping CAMP rising (or promoting CAMP to reduce).
4. the short result of the test proof Radix Et Caulis Acanthopanacis Senticosi that induces has the function of antiviral, antitumor action and immunomodulating and promotion, can be relevant with the high activity function that the short interferon that induces of Radix Et Caulis Acanthopanacis Senticosi polysaccharide is brought into play.Interferon may be a kind of important medium of this pharmacodynamics effect.
5. Radix Acanthopanacis Senticosi Pharmacological action study: the pure extractum aqueous solution of the root of Radix Acanthopanacis Senticosi, rhizome; the energy enhancing body's immunological function; also can enhancing body to the nonspecific resistance of various destructive stimuluses; and the pathological change that body exists is hyperfunction or lowly all can makes it recover normal promptly have and adjust or the normalization effect.
6. Radix Acanthopanacis Senticosi has multiple pharmacological effect, and it is by many-sided promotion and Accommodations such as nervus centralis, immunity, endocrine, metabolism, and remarkable enhancing body premunition.
1. Fructus Lycii contains carotene, thiamine, riboflavin, nicotinic acid, ascorbic acid.Still isolate cupreol, linoleic acid.
2. lipotropy: the infusion of Fructus Lycii (stomach is irritated in 20%8 milliliter/skies) to the mice of being poisoned by carbon tetrachloride, has and slightly suppresses the deposition of fat in hepatocyte, promotes the newborn effect of hepatocyte.
3. this product has the phagocytosis that strengthens reticuloendothelial system, strengthens peripheral leukocytes and the effect of the nonspecific immunity of raising is arranged, and can strengthen cell and humoral immunization effect; Hemopoietic function there is facilitation.
4. the lycium barbarum teabag can improve immune function of mice, and experiment detects immunoglobulin IgG, IgA, the IgM content of each group, antibody-producting cell and antibody titer, and experimental group numerical value is higher than matched group as a result.
Fructus Ligustri Lucidi 1. this product contains oleanolic acid, mannitol, glucose, Palmic acid, stearic acid, oleic acid, linoleic acid.
2. Fructus Ligustri Lucidi can promote lymphocyte that PHA is replied, but own and no mitogen effect, Fructus Ligustri Lucidi can be by strengthening the activity of cell surface receptor, may be to promote intracellular receptor to be secreted into cell surface rapidly and the binding ability that strengthens cell surface receptor, not influence the aggregate velocity of receptor and the secretion by promotion secondary signal (IL-2) and receptor thereof promotes cell proliferation rate.
3. to the leukopenia of chemotherapy, caused by radiation, function of increasing leukocyte is arranged.Can promote healthy people's lymphoblastic transformation, rising periphery leukocyte strengthens the reticuloendothelial system phagocytic function, and the body fluid of enhancing and immunization of cell are arranged.
1. Fructus Schisandrae Chinensis contains citric acid, malic acid and a small amount of tartaric acid in the dry fruit, still contains monosaccharide, resin and volatilization wet goods.
2. its can enhancing body the phylactic power defensive power of nonspecific stimulation.
3. treat non-icteric type, infectious hepatitis: according to 102 observations, effective percentage is 85.3%, and basic cure rate accounts for 76.4, and Fructus Schisandrae Chinensis has the effect of obvious reduction glutamate pyruvate transaminase to infectious hepatitis, and it is very fast to prove effective.
Herba Epimedii 1. stem, leaf contains the Herba Epimedii glycoside, and leaf still contains volatile oil, ceryl alcohol, thirty-alkane, plant sterol, tannin, oils and fats.Fatty acid in the fatty oil has Palmic acid, stearic acid, oleic acid, linoleic acid.
2. the Herba Epimedii total flavones is to effect of immunologic function, and the result shows that Herba Epimedii has the effect that strengthens cellular immunization and humoral immunization, can improve the activate the phagocytic capacity of macrophage simultaneously.
3. Herba Epimedii electuary treatment leukopenia and to the influence of Copper in Serum, zinc, magnesium: make electuary with unit arrow leaf Herba Epimedii, 15 gram/bags (being equivalent to crude drug), second bag/day Tuesday, were treated 30-45 days altogether at first all three guarantees/day.Need not give birth to high leukocytic and vitamin medicaments during the treatment.This organizes 22 examples, treats 4 examples on request, and closely it cures 3 examples, produce effects 4 examples, effective 4 examples, invalid 3 examples.And measure by serum copper, zinc, content of magnesium and to show that the curative effect of this product is not replenishing of magnesium, but regulate the equilibrium between yin and yang of body, promote Absorption to zinc, magnesium.
Herb Gynostemmae Pentaphylli 1. this product contains sterol, saccharide, pigment, sweet taste composition and glycoside.Isolate 52 kinds of dammarane type gypenoside and Radix Ginseng soap Rb with the similar skeleton of ginsenoside in the Herb Gynostemmae Pentaphylli
1, Rb
3, Rd, F
2And composition such as two kinds of protopanoxadiols or triol.
2. trace elements determination: it is the necessary for human body trace element that Herb Gynostemmae Pentaphylli contains 10 kinds, and they are: Fe, Zn, Cu, Mo, Mn, Mi, Ni, Cr, V, Se, Si.
3. the Herb Gynostemmae Pentaphylli glycoside compound has significantly strong shape effect, and Radix Ginseng sample " adaptogen " effect, can prolong the life of normal animal, has that anti-inner feelings is old, antitumor action.
4. feed rat with the Herb Gynostemmae Pentaphylli extracting solution, experiment is proof tentatively, and immunity has facilitation to Herb Gynostemmae Pentaphylli to body cell.
5. strong precious tea experimental study on anticancer: strong precious tea is to be the pouring type beverage that raw material is made with the Herb Gynostemmae Pentaphylli, and this tea has remarkable inhibitory action to sarcoma 180.Drink 8% strong precious tea to mice, continuous 13 days, can significantly suppress the growth of Mus body tumor, the tumor piece is obviously dwindled and can suppress cancer ascites to form, significantly reduce cancerous cell number in the ascites.
1. the Radix Astragali contains sucrose, aldehydic acid, phlegmatic temperament, several aminoacid, bitter principle, choline, betanin, folic acid.
2. this product can improve immunologic function, and astragalus polysaccharides can make animal splenauxe, and Intradermal plasma cell hypertrophy is can enhancing antibody synthetic, and immunosuppressant influence such as antagonism meticortelone.The Radix Astragali can prolong some cell survival.The Radix Astragali has facilitation to interferon system.
3. the Radix Astragali can improve non-specific immunity, as improving the phagocytic function of lymph rate or reticuloendothelial system.The Radix Astragali can also increase plasma C AMP content, promotes humoral immunization, improves immunoglobulin content, has the immunologic function dual regulation.
1. Poria mainly contains β-pachyman, pachymic acid, protein, fat, lecithin, choline, tissue acid, potassium salt etc.
2. pachyman can improve the macrophage phagocytic rate, stimulates the β cell, and the effect that strengthens cell immunocompetent is arranged, and can significantly rise with content of immunoglobulin IgG again, has illustrated to improve the humoral immune function effect.
3. used the carboxymethyl pachyman clinical practice 3 years; the dissimilar malignant tumor of treatment 70 examples; and use separately; cooperationization, radiotherapy and operative treatment, pachyman energy health invigorating are also arranged; improve the thin immunologic function of body, stimulating appetite improves symptom; protection bone marrow, alleviate put, the reaction of chemotherapy.
Radix Ophiopogonis, 1. the tuber of this product contained multiple steroid saponin, also contained Sitosterolum, stigmasterol.The tuber of big Radix Ophiopogonis contains steroid saponin, cupreol, aminoacid, vitamin A, glucose.
2. antibacterial action: Radix Ophiopogonis powder external to some antibacterial actions such as Staphylococcus albus, escherichia coli.
3. can strengthen netted interior and system's phagocytic activity Radix Ophiopogonis, increase the periphery leukocyte, the human body immunity improving function.
1. Herba Hedyotidis Diffusae contains oleanolic acid, cupreol, para-position coumaric acid and flavonoid glycoside, Herba Hedyotidis Diffusae element etc.
2. Herba Hedyotidis Diffusae have antitumor action, and this product is tried out in multiple cancers such as esophageal carcinoma, gastric cancer, rectal cancer in recent years, and obtains certain curative effect.
3. the internal energy stimulation of body netted in and system's hypertrophy, enhancing antibody is synthetic, skein cell, leukocytic phagocytic activity is strengthened, and reach the anti-inflammation purpose.
Fructus Jujubae 1. this product contains egg matter, saccharide, organic acid, phlegmatic temperament, vitamin A, B
2, C, micro-calcium, phosphorus, ferrum.
2. Fructus Jujubae has the effect of the liver protecting, increase muscular strength and weight increase.
3. reduce serum GPT levels: all effective to the patient that the serum transaminase vigor of acute and chronic, liver cirrhosis patient improves.
Green tea 1. modern study has the effect of anti-tumor.
Important feature of the present invention is:
1, prescription is tight, unique, scientific has the generally important meaning of control to immune disease by force, and effect is sure.
2, the prevention of diseae, put prevention first; Treatment is for secondary.
3, drug administration of the present invention is convenient, anosisly all can prevent, illly all can control; Everybody is all available.
Another important feature of the present invention is the nutrient substance that contains multiple needed by human body in the medicament as polysaccharide, vitamins, protein, fat, aminoacid, folic acid, fruit acid, carotene, mannitol, sweetener etc.Various trace elements: calcium, phosphorus, ferrum, zinc, magnesium etc.Help the synthetic of immune antibody.Body metabolism and defying age process are played a driving role.
The clinical use result of the present invention shows that following advantage is arranged:
1, to select the homologous natural edible plant amedica of medicated diet for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation.Utilize the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of to prevent and treat immune disease, nontoxic to human body.
2, the present invention need not to decoct no bitterness sense; Nutritious, taking convenience; Then drink yearningly, meet the national health law regulation.
3, can prolong some cell survival, slow down aging, life lengthening.
4, medicine of the present invention is anosis all can prevent, illly all can control.The health care immunity good merchantable brand that everybody all need use.
For showing the preventive effect of medicine of the present invention to immune disease, the present invention has done system's clinical observation through 315 examples to the dissimilar disease of each group.And select medical history, the state of an illness, age, sex all to carry out.228 examples are matched group.Say something for clearer, front and back are the time more than a year, and the present invention has selected the tumor of same disease to compare.In admissions office of tumour hospital and external patient.Cooperate radiotherapy to observe observation period 1 month to 100 routine New Development patients with lung cancer with medicine of the present invention at different times.Age 35-70 year, male 73 examples, women 27 examples.Instructions of taking: day clothes 2-3 time, the 3-10 gram/time.Matched group 72 examples, appetite is promoted as a result, and doing well,improving is remarkable; Spirit takes a turn for the better.Descend through looking into CEA concentration thereupon.Test group does not use the untoward reaction that radiotherapy occurred before the medicine of the present invention obvious, lassitude, lusterless complexion; Loss of appetite or anorexia, doing well,improving is not obvious.Increase through looking into the CEA concentration change; Constant or descend, rise or clinical deterioration rates.Result of the test sees Table (1,2).
Lung cancer patient radiotherapeutic effect and CEA concentration are followed up a case by regular visits to before table 1 treatment
| Test group | CEA concentration change example number tumor disappear clinical constant tumor development normal value clinical improvements (＞3.9ng/mL) clinical deterioration rates (＜2ng/mL) (＜2ng/mL) (＞4-9.9ng/mL) |
| Constant 42 2 36 4 declines 30 28-2 raise 28 69 13 |
Table 2 treatment back lung cancer patient radiotherapeutic effect and CEA concentration are followed up a case by regular visits to
| Matched group | CEA concentration change example number tumor disappear clinical constant tumor development normal value clinical improvements (＞3.9ng/mL) clinical deterioration rates (＜2ng/mL) (＜2ng/mL) (＞4-9.9ng/mL) |
| Constant 30 4 24 2 declines 26 26--raise 16 44 13 |
During to 357 veteran cadre's health screenings, wherein one is the generaI investigation of hepatitis B in local hospital.Normally healthy population is gathered serum and is detected anti--HBs, and anti--HBs sun changes or the unconspicuous patient of antibody titer the male to have selected 100 examples to detect.Take medicine of the present invention then, 1 month observation period, instructions of taking: day clothes 2-3 time, the 3-10 gram/time.Matched group 79 examples, the result detects, and anti--HBs sun commentaries on classics or antibody titer are significantly increased.
In the Medicine and Surgery outpatient service of hospital of a few family, different time, a fairly large number of patient of alopecia when having selected 50 examples whenever with hair washing.Scope 30-100 root, male 33 examples, women 17 examples.Age 18-50 year, the course of disease 3 months-1 year.Carry out method and divide the two-stage nitration time to observe by doctor's advice, 1 month observation period, used medicine of the present invention respectively 15 days, day clothes 2-3 time, the 3-10 gram/time.Matched group 42 examples, the equal 18-53 root of alopecia quantity when the result washes hair.Continue by former instructions about how to take medicine and to take 15 days.Matched group 31 examples, the equal 3-10 root of alopecia quantity when the result washes hair.
In the outpatient service of epidemic prevention station internal medicine, beat among the regular flu patient of serum albumin prevention, selected 35 examples month 1-3 flu object at different time.Man's 12 examples, women 23 examples; Age 15-60 year, course of disease 1-15; 1 month observing time, use medicine of the present invention; Day obeys 2-3 time, the 3-10 gram/time, matched group 27 examples.The result has 2 examples to catch a cold once, and reason is that quantity of motion is excessive, direct stimulation and causing.
In hospital dermatology department and traditional Chinese medical science clinic, selected the urticaria patient of 30 examples recurrences in every month in the different times.Man's 7 examples, women 23 examples; Age 18-60 year.Course of disease 1-10; 30 days observing times, use medicine of the present invention respectively.Day obeys 2-3 time, the 3-10 gram/time, matched group 19 examples.The result has 3 examples 1-2 time repeatedly, searches former because the antigen antibody complex reaction.Following the doctor's advice continues by this method takes, and observes 1 month; Matched group 2 examples, the result does not have appearance repeatedly.
The conventional operating position of medicine of the present invention: can obey 2-3 time every day according to the patient's condition when doing treatment, the 3-10 gram/time.Needing during anosis prevention take 1-3 time every several days, 3-10 restrains/time.Often take developing of disease preventing and treating effectively.
Show by differential diagnosis in tcm treatment: medicine of the present invention mostly is nourishing the liver and kidney, replenishing QI to invigorate the spleen and have that skin just consolidates, eliminating evil effect.Go down with the modern medicine immunologic function and the human righteousness is deficient, particularly cellular immune level lowly has substantial connection.Promptly call: positive QI-insufficiency, pathogen is had a surplus; The healthy energy internal memory, evil irrelevant.The meaning of the developing of disease, treatment and the special connection of healthy energy is described.
Modern pharmacological research shows: medicine of the present invention has antitumor, antiviral, the sterilization mattress that goes out.Strengthen the function of cellular immunization and humoral immunization and reticuloendothelial system, improve the non-specific and specific immune function of body.
Test statistics shows: medicine of the present invention is observed 315 examples altogether, matched group 228 examples.100 examples cooperate the control test of radiotherapy to lung cancer patient.100 examples are gathered the control test that serum detects anti--HBs sun commentaries on classics or antibody titer to healthy population.115 examples to lose hair, often flu, urticaria patient do control test.It is total effective rate 100% as a result.
Claims (6)
1, a kind ofly regulates its feature of immunizing health tea it is the medicament of being made by following proportion raw material.The blue 0.1-0.5 of Radix Et Caulis Acanthopanacis Senticosi 0.1-0.5 gram Fructus Lycii 0.1-0.5 gram Fructus Ligustri Lucidi 0.1-0.5 gram Fructus Schisandrae Chinensis 0.1-0.5 gram Herba Epimedii 0.1-0.5 gram strand glue restrains yellow late-maturing 0.1-0.5 gram Poria 0.1-0.5 gram 0.1-0.5 Radix Ophiopogonis gram Herba Hedyotidis Diffusae 0.1-0.5 gram Fructus Jujubae 0.5-2.5 gram green tea 0.5-2.5 gram
2, according to claims 1 described medicine of preventing and treating immune disease, wherein the weight proportion of each raw material is: Radix Acanthopanacis Senticosi 0.2-0.4 gram Fructus Lycii 0.2-0.4 gram Fructus Ligustri Lucidi 0.2-0.4 gram Fructus Schisandrae Chinensis 0.2-0.4 gram Herba Epimedii 0.2-0.4 gram Herb Gynostemmae Pentaphylli 0.2-0.4 gram Radix Astragali 0.2-0.4 gram Poria 0.2-0.4 gram 0.2-0.4 Radix Ophiopogonis gram Herba Hedyotidis Diffusae 0.2-0.4 gram Fructus Jujubae 0.5-1.5 gram green tea 0.5-1.5 gram
3, according to claims 1 described medicine of preventing and treating immune disease, wherein the weight proportion of each raw material is: the Radix Et Caulis Acanthopanacis Senticosi 0.3 gram Fructus Lycii 0.3 Fructus Ligustri Lucidi 0.3 gram Fructus Schisandrae Chinensis 0.3 gram Herba Epimedii 0.3 gram Herb Gynostemmae Pentaphylli 0.3 gram Radix Astragali 0.3 gram Poria 0.3 gram 0.3 gram Herba Hedyotidis Diffusae Radix Ophiopogonis 0.3 gram Fructus Jujubae 1 gram green tea 1 gram
4,, it is characterized in that said medicament is a said dosage form on the pharmaceutics according to claim 1, the 2 or 3 described medicines of preventing and treating immune disease.
5, the medicine of preventing and treating immune disease according to claim 4 is characterized in that said medicament is powder or graininess powder.
6, the described preparation method of preventing and treating the medicine of immune disease of claim 5 is characterized in that earlier Fructus Lycii, Radix Ophiopogonis being ground into 40-120 order powdery-15 ℃ of following lyophilizations; Fructus Jujubae is ground into 40-120 order powdery-15 ℃ of following lyophilizations; Again Radix Et Caulis Acanthopanacis Senticosi, Fructus Ligustri Lucidi, Fructus Schisandrae Chinensis, Herba Epimedii, Herb Gynostemmae Pentaphylli, the Radix Astragali, Poria, Herba Hedyotidis Diffusae are ground into 40-120 order powdery after air-dry; Folium Camelliae sinensis is ground into 40-120 order powdery after air-dry.Above-mentioned whole powder components by after the described mixed, are carried out air slaking, sterilization treatment 10-30 minute under 40-60 ℃, make powder.
Be packed as the fractional pack of 3-10 gram weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96107685 CN1169315A (en) | 1996-06-27 | 1996-06-27 | Immunity-regulating health-care tea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96107685 CN1169315A (en) | 1996-06-27 | 1996-06-27 | Immunity-regulating health-care tea |
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|---|---|
| CN1169315A true CN1169315A (en) | 1998-01-07 |
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| CN 96107685 Pending CN1169315A (en) | 1996-06-27 | 1996-06-27 | Immunity-regulating health-care tea |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100382832C (en) * | 2004-04-22 | 2008-04-23 | 株洲千金药业股份有限公司 | Health foods in use for improving symptom in climacteric period of female and fabricating method |
| CN101904374A (en) * | 2010-07-01 | 2010-12-08 | 秦皇岛市北戴河北芪神茶有限公司 | Preparation method of astragali tea |
| CN101617726B (en) * | 2009-08-14 | 2012-03-28 | 杨正 | Black and red mixed tea drink for males for losing weight, tonifying qi and reducing fat |
| CN103431114A (en) * | 2013-08-30 | 2013-12-11 | 黑龙江省新曙光刺五加生物科技开发有限公司 | Manyprickle acanthopanax root cold-prevention tea and preparation method thereof |
| CN104397282A (en) * | 2014-11-27 | 2015-03-11 | 青岛申达高新技术开发有限公司 | Tranquilization and brain tonifying eleutherococcus senticosus healthare tea and preparation method thereof |
| CN104721543A (en) * | 2015-02-11 | 2015-06-24 | 无锡欣安贝生物技术有限公司 | Traditional Chinese medicinal immunomodulator and preparation method thereof |
| CN105685324A (en) * | 2016-03-15 | 2016-06-22 | 王�锋 | Healthcare tea with multiple healthcare effects and making method thereof |
| CN106578199A (en) * | 2016-12-16 | 2017-04-26 | 横琴智库转化医学有限公司 | Oral solution for preventing malignant tumors |
-
1996
- 1996-06-27 CN CN 96107685 patent/CN1169315A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100382832C (en) * | 2004-04-22 | 2008-04-23 | 株洲千金药业股份有限公司 | Health foods in use for improving symptom in climacteric period of female and fabricating method |
| CN101617726B (en) * | 2009-08-14 | 2012-03-28 | 杨正 | Black and red mixed tea drink for males for losing weight, tonifying qi and reducing fat |
| CN101904374A (en) * | 2010-07-01 | 2010-12-08 | 秦皇岛市北戴河北芪神茶有限公司 | Preparation method of astragali tea |
| CN103431114A (en) * | 2013-08-30 | 2013-12-11 | 黑龙江省新曙光刺五加生物科技开发有限公司 | Manyprickle acanthopanax root cold-prevention tea and preparation method thereof |
| CN104397282A (en) * | 2014-11-27 | 2015-03-11 | 青岛申达高新技术开发有限公司 | Tranquilization and brain tonifying eleutherococcus senticosus healthare tea and preparation method thereof |
| CN104721543A (en) * | 2015-02-11 | 2015-06-24 | 无锡欣安贝生物技术有限公司 | Traditional Chinese medicinal immunomodulator and preparation method thereof |
| CN105685324A (en) * | 2016-03-15 | 2016-06-22 | 王�锋 | Healthcare tea with multiple healthcare effects and making method thereof |
| CN106578199A (en) * | 2016-12-16 | 2017-04-26 | 横琴智库转化医学有限公司 | Oral solution for preventing malignant tumors |
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