CN102630939B - Health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy and preparation method thereof - Google Patents
Health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy and preparation method thereof Download PDFInfo
- Publication number
- CN102630939B CN102630939B CN2012101196392A CN201210119639A CN102630939B CN 102630939 B CN102630939 B CN 102630939B CN 2012101196392 A CN2012101196392 A CN 2012101196392A CN 201210119639 A CN201210119639 A CN 201210119639A CN 102630939 B CN102630939 B CN 102630939B
- Authority
- CN
- China
- Prior art keywords
- weight portions
- health food
- weight
- health
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 235000013305 food Nutrition 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims description 17
- 208000030507 AIDS Diseases 0.000 title abstract description 39
- 235000005911 diet Nutrition 0.000 title abstract description 5
- 230000036039 immunity Effects 0.000 title abstract description 5
- 230000000378 dietary effect Effects 0.000 title abstract description 4
- 238000002560 therapeutic procedure Methods 0.000 title abstract description 4
- 239000003814 drug Substances 0.000 claims abstract description 60
- 241001116389 Aloe Species 0.000 claims abstract description 23
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 22
- 235000011201 Ginkgo Nutrition 0.000 claims abstract description 20
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract description 20
- 241001248610 Ophiocordyceps sinensis Species 0.000 claims abstract description 20
- 235000013717 Houttuynia Nutrition 0.000 claims abstract description 19
- 240000007164 Salvia officinalis Species 0.000 claims abstract description 18
- 150000001413 amino acids Chemical class 0.000 claims abstract description 9
- 150000004676 glycans Chemical class 0.000 claims abstract description 7
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 7
- 239000005017 polysaccharide Substances 0.000 claims abstract description 7
- 229940088594 vitamin Drugs 0.000 claims abstract description 7
- 229930003231 vitamin Natural products 0.000 claims abstract description 7
- 235000013343 vitamin Nutrition 0.000 claims abstract description 7
- 239000011782 vitamin Substances 0.000 claims abstract description 7
- 240000000691 Houttuynia cordata Species 0.000 claims abstract 4
- 235000013402 health food Nutrition 0.000 claims description 55
- 229940079593 drug Drugs 0.000 claims description 35
- 239000000284 extract Substances 0.000 claims description 26
- 241000205585 Aquilegia canadensis Species 0.000 claims description 20
- 241000218628 Ginkgo Species 0.000 claims description 19
- 235000005412 red sage Nutrition 0.000 claims description 17
- 239000000463 material Substances 0.000 claims description 15
- 239000000796 flavoring agent Substances 0.000 claims description 14
- 235000019634 flavors Nutrition 0.000 claims description 14
- 230000036737 immune function Effects 0.000 claims description 13
- 239000000843 powder Substances 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 10
- 230000006837 decompression Effects 0.000 claims description 9
- 238000005303 weighing Methods 0.000 claims description 9
- 229920002472 Starch Polymers 0.000 claims description 8
- 235000001014 amino acid Nutrition 0.000 claims description 8
- 235000019698 starch Nutrition 0.000 claims description 8
- 239000008107 starch Substances 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 239000002270 dispersing agent Substances 0.000 claims description 4
- 239000003995 emulsifying agent Substances 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 4
- 239000011573 trace mineral Substances 0.000 claims description 4
- 235000013619 trace mineral Nutrition 0.000 claims description 4
- 244000046052 Phaseolus vulgaris Species 0.000 claims description 3
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims description 3
- LPQOADBMXVRBNX-UHFFFAOYSA-N ac1ldcw0 Chemical compound Cl.C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3CCSC1=C32 LPQOADBMXVRBNX-UHFFFAOYSA-N 0.000 claims description 3
- 235000013339 cereals Nutrition 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 235000013336 milk Nutrition 0.000 claims description 3
- 239000008267 milk Substances 0.000 claims description 3
- 210000004080 milk Anatomy 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 229920001542 oligosaccharide Polymers 0.000 claims description 3
- 150000002482 oligosaccharides Chemical class 0.000 claims description 3
- 235000013311 vegetables Nutrition 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 48
- 241000725303 Human immunodeficiency virus Species 0.000 abstract description 26
- 102000004169 proteins and genes Human genes 0.000 abstract description 10
- 108090000623 proteins and genes Proteins 0.000 abstract description 10
- 235000015097 nutrients Nutrition 0.000 abstract description 7
- 244000194101 Ginkgo biloba Species 0.000 abstract description 5
- 230000036541 health Effects 0.000 abstract description 5
- 239000000126 substance Substances 0.000 abstract description 5
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract description 4
- 239000011707 mineral Substances 0.000 abstract description 4
- 235000010755 mineral Nutrition 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 4
- 230000002588 toxic effect Effects 0.000 abstract description 4
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 abstract description 3
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 abstract description 3
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 abstract description 3
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 abstract description 3
- 229930003944 flavone Natural products 0.000 abstract description 3
- 150000002212 flavone derivatives Chemical class 0.000 abstract description 3
- 235000011949 flavones Nutrition 0.000 abstract description 3
- 230000002147 killing effect Effects 0.000 abstract description 3
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract description 3
- 229930182490 saponin Natural products 0.000 abstract description 3
- 150000007949 saponins Chemical class 0.000 abstract description 3
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 abstract description 3
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 208000035240 Disease Resistance Diseases 0.000 abstract 1
- 241000245240 Lonicera Species 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 230000000975 bioactive effect Effects 0.000 abstract 1
- 230000000452 restraining effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 description 23
- 241000700605 Viruses Species 0.000 description 21
- 210000004369 blood Anatomy 0.000 description 17
- 239000008280 blood Substances 0.000 description 17
- 241000758769 Houttuynia Species 0.000 description 15
- 230000006870 function Effects 0.000 description 14
- 230000003203 everyday effect Effects 0.000 description 11
- 238000012360 testing method Methods 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 210000004072 lung Anatomy 0.000 description 9
- 208000024891 symptom Diseases 0.000 description 9
- 206010012735 Diarrhoea Diseases 0.000 description 8
- 229930006000 Sucrose Natural products 0.000 description 8
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 8
- 230000009471 action Effects 0.000 description 8
- 230000036528 appetite Effects 0.000 description 8
- 235000019789 appetite Nutrition 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 8
- 201000010099 disease Diseases 0.000 description 8
- 235000018102 proteins Nutrition 0.000 description 8
- 210000000952 spleen Anatomy 0.000 description 8
- 239000005720 sucrose Substances 0.000 description 8
- 206010007247 Carbuncle Diseases 0.000 description 7
- 206010011224 Cough Diseases 0.000 description 7
- 206010062717 Increased upper airway secretion Diseases 0.000 description 7
- 229940024606 amino acid Drugs 0.000 description 7
- 230000017531 blood circulation Effects 0.000 description 7
- 208000015181 infectious disease Diseases 0.000 description 7
- 210000003734 kidney Anatomy 0.000 description 7
- 210000004185 liver Anatomy 0.000 description 7
- 208000026435 phlegm Diseases 0.000 description 7
- 239000000902 placebo Substances 0.000 description 7
- 229940068196 placebo Drugs 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 230000001976 improved effect Effects 0.000 description 6
- 206010013786 Dry skin Diseases 0.000 description 5
- 230000037396 body weight Effects 0.000 description 5
- 238000001035 drying Methods 0.000 description 5
- 238000010438 heat treatment Methods 0.000 description 5
- 230000003908 liver function Effects 0.000 description 5
- 230000000144 pharmacologic effect Effects 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 230000003014 reinforcing effect Effects 0.000 description 5
- 238000011160 research Methods 0.000 description 5
- 210000002345 respiratory system Anatomy 0.000 description 5
- 241000193830 Bacillus <bacterium> Species 0.000 description 4
- 206010019233 Headaches Diseases 0.000 description 4
- 102000004407 Lactalbumin Human genes 0.000 description 4
- 108090000942 Lactalbumin Proteins 0.000 description 4
- 241000187479 Mycobacterium tuberculosis Species 0.000 description 4
- AIGAZQPHXLWMOJ-UHFFFAOYSA-N Tanshinone I Chemical compound C1=CC2=C(C)C=CC=C2C(C(=O)C2=O)=C1C1=C2C(C)=CO1 AIGAZQPHXLWMOJ-UHFFFAOYSA-N 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- 208000006673 asthma Diseases 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
- 231100000869 headache Toxicity 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 210000004698 lymphocyte Anatomy 0.000 description 4
- 230000036407 pain Effects 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 3
- 208000002193 Pain Diseases 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 229930003268 Vitamin C Natural products 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- 230000003115 biocidal effect Effects 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 206010016256 fatigue Diseases 0.000 description 3
- 210000000987 immune system Anatomy 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 235000019154 vitamin C Nutrition 0.000 description 3
- 239000011718 vitamin C Substances 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- PAFLSMZLRSPALU-MRVPVSSYSA-N (2R)-3-(3,4-dihydroxyphenyl)lactic acid Chemical group OC(=O)[C@H](O)CC1=CC=C(O)C(O)=C1 PAFLSMZLRSPALU-MRVPVSSYSA-N 0.000 description 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- TUGAUFMQYWZJAB-FPLPWBNLSA-N 5-[(8Z)-pentadec-8-enyl]resorcinol Chemical compound CCCCCC\C=C/CCCCCCCC1=CC(O)=CC(O)=C1 TUGAUFMQYWZJAB-FPLPWBNLSA-N 0.000 description 2
- IKHGUXGNUITLKF-UHFFFAOYSA-N Acetaldehyde Chemical compound CC=O IKHGUXGNUITLKF-UHFFFAOYSA-N 0.000 description 2
- AFHJQYHRLPMKHU-XXWVOBANSA-N Aloin Natural products O=C1c2c(O)cc(CO)cc2[C@H]([C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O2)c2c1c(O)ccc2 AFHJQYHRLPMKHU-XXWVOBANSA-N 0.000 description 2
- 201000004384 Alopecia Diseases 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 2
- SRLTUZDQBFYLQI-FPLPWBNLSA-N Bilobol Natural products Oc1c(CCCCCCC/C=C\CCCCCC)ccc(O)c1 SRLTUZDQBFYLQI-FPLPWBNLSA-N 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- PAFLSMZLRSPALU-QMMMGPOBSA-N Danshensu Natural products OC(=O)[C@@H](O)CC1=CC=C(O)C(O)=C1 PAFLSMZLRSPALU-QMMMGPOBSA-N 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 102000006587 Glutathione peroxidase Human genes 0.000 description 2
- 108700016172 Glutathione peroxidases Proteins 0.000 description 2
- 206010018612 Gonorrhoea Diseases 0.000 description 2
- 208000031886 HIV Infections Diseases 0.000 description 2
- 239000009636 Huang Qi Substances 0.000 description 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 description 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 2
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 2
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 description 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 2
- 239000004472 Lysine Substances 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 208000005384 Pneumocystis Pneumonia Diseases 0.000 description 2
- 206010073755 Pneumocystis jirovecii pneumonia Diseases 0.000 description 2
- 208000003251 Pruritus Diseases 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- PAFLSMZLRSPALU-UHFFFAOYSA-N Salvianic acid A Natural products OC(=O)C(O)CC1=CC=C(O)C(O)=C1 PAFLSMZLRSPALU-UHFFFAOYSA-N 0.000 description 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 108010073771 Soybean Proteins Proteins 0.000 description 2
- 229930183118 Tanshinone Natural products 0.000 description 2
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 2
- 239000004473 Threonine Substances 0.000 description 2
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 2
- 208000037386 Typhoid Diseases 0.000 description 2
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 2
- CPUHNROBVJNNPW-UHFFFAOYSA-N aloin A Natural products OC1C(O)C(O)C(CO)OC1OC1C2=CC(CO)=CC(O)=C2C(=O)C2=C(O)C=CC=C21 CPUHNROBVJNNPW-UHFFFAOYSA-N 0.000 description 2
- AFHJQYHRLPMKHU-WEZNYRQKSA-N aloin B Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1[C@H]1C2=CC(CO)=CC(O)=C2C(=O)C2=C(O)C=CC=C21 AFHJQYHRLPMKHU-WEZNYRQKSA-N 0.000 description 2
- 231100000360 alopecia Toxicity 0.000 description 2
- MWPLVEDNUUSJAV-UHFFFAOYSA-N anthracene Chemical compound C1=CC=CC2=CC3=CC=CC=C3C=C21 MWPLVEDNUUSJAV-UHFFFAOYSA-N 0.000 description 2
- 230000002929 anti-fatigue Effects 0.000 description 2
- 238000011225 antiretroviral therapy Methods 0.000 description 2
- 239000003443 antiviral agent Substances 0.000 description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 description 2
- 230000008034 disappearance Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 208000006454 hepatitis Diseases 0.000 description 2
- 231100000283 hepatitis Toxicity 0.000 description 2
- 235000008216 herbs Nutrition 0.000 description 2
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 2
- 230000001900 immune effect Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- AFHJQYHRLPMKHU-UHFFFAOYSA-N isobarbaloin Natural products OC1C(O)C(O)C(CO)OC1C1C2=CC(CO)=CC(O)=C2C(=O)C2=C(O)C=CC=C21 AFHJQYHRLPMKHU-UHFFFAOYSA-N 0.000 description 2
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 2
- 229960000310 isoleucine Drugs 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 description 2
- 210000003563 lymphoid tissue Anatomy 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229930182817 methionine Natural products 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 230000003119 painkilling effect Effects 0.000 description 2
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 2
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 2
- 201000000317 pneumocystosis Diseases 0.000 description 2
- 230000005180 public health Effects 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 description 2
- 229910052711 selenium Inorganic materials 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 235000019710 soybean protein Nutrition 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 201000008297 typhoid fever Diseases 0.000 description 2
- 239000004474 valine Substances 0.000 description 2
- 229910052720 vanadium Inorganic materials 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 2
- 229960002555 zidovudine Drugs 0.000 description 2
- YXHVCZZLWZYHSA-UHFFFAOYSA-N (Z)-6-[8-pentadecenyl]salicylic acid Natural products CCCCCCC=CCCCCCCCC1=CC=CC(O)=C1C(O)=O YXHVCZZLWZYHSA-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 241001061264 Astragalus Species 0.000 description 1
- 201000001178 Bacterial Pneumonia Diseases 0.000 description 1
- 241000588832 Bordetella pertussis Species 0.000 description 1
- 210000001239 CD8-positive, alpha-beta cytotoxic T lymphocyte Anatomy 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- -1 Cobastab 6 Chemical compound 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 244000247747 Coptis groenlandica Species 0.000 description 1
- 235000002991 Coptis groenlandica Nutrition 0.000 description 1
- 206010011831 Cytomegalovirus infection Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- YXHVCZZLWZYHSA-FPLPWBNLSA-N Ginkgoic acid Chemical compound CCCCCC\C=C/CCCCCCCC1=CC=CC(O)=C1C(O)=O YXHVCZZLWZYHSA-FPLPWBNLSA-N 0.000 description 1
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000009889 Herpes Simplex Diseases 0.000 description 1
- 208000007514 Herpes zoster Diseases 0.000 description 1
- 241000713340 Human immunodeficiency virus 2 Species 0.000 description 1
- 206010061598 Immunodeficiency Diseases 0.000 description 1
- 208000029462 Immunodeficiency disease Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 208000007766 Kaposi sarcoma Diseases 0.000 description 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 description 1
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 description 1
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 description 1
- 208000037093 Menstruation Disturbances Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- 241000192041 Micrococcus Species 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 206010029412 Nightmare Diseases 0.000 description 1
- 229940122313 Nucleoside reverse transcriptase inhibitor Drugs 0.000 description 1
- 208000001388 Opportunistic Infections Diseases 0.000 description 1
- 208000007027 Oral Candidiasis Diseases 0.000 description 1
- 206010067472 Organising pneumonia Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 241000228150 Penicillium chrysogenum Species 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 101100152436 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) TAT2 gene Proteins 0.000 description 1
- 206010040007 Sense of oppression Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 241000607764 Shigella dysenteriae Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 206010066901 Treatment failure Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 108010093894 Xanthine oxidase Proteins 0.000 description 1
- 102100033220 Xanthine oxidase Human genes 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 206010000059 abdominal discomfort Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 229940069521 aloe extract Drugs 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 235000021120 animal protein Nutrition 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000001986 anti-endotoxic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000798 anti-retroviral effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 235000006533 astragalus Nutrition 0.000 description 1
- QUQPHWDTPGMPEX-UTWYECKDSA-N aurantiamarin Natural products COc1ccc(cc1O)[C@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1 QUQPHWDTPGMPEX-UTWYECKDSA-N 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 238000010322 bone marrow transplantation Methods 0.000 description 1
- 208000023367 bronchiolitis obliterans with obstructive pulmonary disease Diseases 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 201000009805 cryptogenic organizing pneumonia Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000021196 dietary intervention Nutrition 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 235000019564 dysgeusia Nutrition 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000003181 encephalopathic effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 229940125777 fusion inhibitor Drugs 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 229930184727 ginkgolide Natural products 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000007813 immunodeficiency Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 235000019136 lipoic acid Nutrition 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 230000000527 lymphocytic effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 210000000822 natural killer cell Anatomy 0.000 description 1
- 208000020470 nervous system symptom Diseases 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 229940042402 non-nucleoside reverse transcriptase inhibitor Drugs 0.000 description 1
- 239000002726 nonnucleoside reverse transcriptase inhibitor Substances 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 208000033808 peripheral neuropathy Diseases 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229940007046 shigella dysenteriae Drugs 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 210000004233 talus Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy. The health-care food comprises the following traditional Chinese medicine components and food accessories by weight part: 3-20 parts of cordyceps sinensis, 10-16 parts of honeysuckles, 10-16 parts of cordate houttuynia, 10-16 parts of roots of red-rooted salvia, 13-20 parts of ginkgo nuts, 13-20 parts of dried tangerines and 3-20 parts of aloes. The health-care food contains various bioactive substances such as polysaccharide, cordycepin, biological flavone, active protein, saponin, vitamins, amino acid, mineral substances, and the like; the special nutrient substance required by an organism is fully replenished; the disease resistance of the organism is completely increased; the immunity is protected and increased; the specific active protein has a specific restraining and killing effect for HIV (Human Immunodeficiency Virus), so that a patient can quickly recover health and the AIDS even can be treated; and no toxic or side effect is found.
Description
Technical field
The present invention relates to a kind of health food for the treatment of and preventing AIDS, be specifically related to a kind of treatment of Chinese medical extract and health food that prevents AIDS of comprising.
Background technology
Medical science full name of AIDS be " acquired immunodeficiency syndrome " (translate again: acquired immunity defective disease), the transliteration of english abbreviation AIDS: Acquired Immune Deficiency Syndrome.Found first and be identified in the U.S. in 1981.Once be translated into " AIDS ", " liking dead sick ".Be divided into amphitypy: infectious disease that " human immunodeficiency virus " (HIV-human immunodeficiency virus) (claiming AIDS virus again) caused that HIV-1 type and HIV-2 type are human infections.AIDS virus HIV is a kind of virus that can attack the human immune system.As target of attack, considerable damage T4 lymphoid tissue produces high fatefulue interior depleted most important T4 lymphoid tissue among the human immune system for it.This virus infects in human body throughout one's life, destroys people's immunologic balance, makes human body become the carrier of various diseases.The incubation period average out to 8-10 of AIDS virus in human body.
The AIDS diagnosis standard is: popular medical history, laboratory examination HIV virus antibody positive are arranged, add any one person in following 16, can be experiment and be diagnosed as AIDS.If HIV antibody positive, and CD4
+T lymphocyte number＜200 μ L also can be experiment and is diagnosed as AIDS.
(1) agnogenic lasting irregular heating reaches 38 ℃, and the duration is more than one month;
(2) the chronic diarrhea number of times continues more than one month more than every day 3 times;
Body weight descends more than 10% in (3) 6 months;
(4) oral Candida albicans of outbreak infects repeatedly;
(5) herpes simplex infections of outbreak or herpes zoster virus infect repeatedly;
(6) pneumocystis carinii pneumonia (PCP);
(7) bacterial pneumonia that shows effect repeatedly;
(8) activity in conjunction with or take the Mycobacterium tuberculosis disease;
(9) deep fungal infection;
(10) central nervous system occupying lesion;
(11) dementia appears in young and middle-aged people;
(12) activity cytomegalovirus infection;
(13) arc worm encephalopathic;
(14) Penicillium notatum infects;
(15) septicemia that takes place repeatedly;
(16) Kaposi sarcoma of skin and mucosa or internal organ, lymthoma.
International treatment is prepared alliance (International Treatment Preparedness Coalition) and was disclosed on May 25th, 2006, in the most serious country of those HIV infections, ten hundreds of AIDS patients is effective medicine and can't well being treated for want of.Be mainly antiviral therapy at present, the single drug weak effect easily produces resistance, makes the treatment failure, existing drug combination--HAART---efficient ARTs (highly active anti-retroviral therapy HAART) that adopt more.Since first kind of AIDS virus resisting medicine Zidovudine March in 1987 (AZT) comes out, the medicine that is used for the AIDS clinical treatment by FDA (FDA) approval reaches 27 kinds of 4 big classes, comprises efabirenz (NRTI), non-nucleoside reverse transcriptase inhibitor (NNRTI), protease inhibitors (PI) and fusion inhibitor (Fusion Inhibitors).From HAART in 1996 be used for clinical since, the M ﹠ M of AIDS obviously descends, patient's immunologic function obtains rebuilding, life quality has obtained remarkable improvement.But HAART can only control the active replication of HIV, the virus in the infected's body can not be removed fully, needs to take medicine for a long time or all the life.Simultaneously, problems such as poisonous side effect of medicine, drug resistance, compliance have also limited the application of HAART." HAART " was once sensational, even but discover now and use 3 kinds even 4 kinds of medicines can not remove AIDS virus in the human body fully simultaneously.On the contrary, after a period of time of holing up in the body, viral load also may rise on a large scale.HAART is duplicated reducing HIV, and the control PD is evident in efficacy, but its side effect also is fairly obvious.Side effect totally is shown as: peripheral neuropathy, pancreatitis, dysfunction of liver, insomnia, headache and dizzy, heating, n and V, diarrhoea, stomatitis, gastritis, fash, hepatitis, central nervous system symptom etc., hyperglycaemia, dysgeusia, and may increase haemophiliac's hemorrhage chance.Simultaneously, this treatment is annual will to spend expense as the astronomical figure, and the patient of most of developing countries is difficult to accept.Cost for each person every year is 1.2 ten thousand U.S. dollars approximately.
Current, the latest Progress for the treatment of AIDS also comprises nutrition treatment, stem cell bone-marrow transplantation and treatment by Chinese herbs.According to " orthomolecular medicine " (Dr.Harold D.Foster ' s, NUTRIENTS BOOST NATURAL ANTI-RETROVIRAL ENZYME IN HIV-INFECTED PATIENTS, Orthomolecular Medicine, October 25,2007) report, a clinical testing of being undertaken by the Men Ge hospital in Uganda Kampala shows that nutritional intervention can be improved quality of life that has infected the human immunodeficiency virus person and the morbidity that obviously delays its AIDS.This test is divided into 2 groups to 310 patients, contains multivitamin and mineral matter, the capsule of totally 30 kinds of nutrients one group of every day; Another group contains the capsule of identical nutrient, and gives extra polyphenoils, and as selenium, N-acetylcystein, alpha-lipoic acid, purpose is to improve natural anti-reverse transcription enzyme, the level of glutathione peroxidase.The researcher also monitors the influence of nutrient to CD4T lymphocyte, body weight and each quality of life parameter.263 patients have finished this test, two groups average CD4T lymphocyte and glutathione peroxidase level all obviously improve, and average weight has increased about 1 kilogram, and the health aspect also has clear improvement, many patients say that appetite obviously increases, and can walk farther road.
Studies show that the coptis, honeysuckle, Radix Glycyrrhizae, these common Chinese medicines of Radix Angelicae Sinensis, perhaps AIDS virus is had resistant function.A few days ago, the China national AIDS expert of the Committee of Experts, the Chinese department of traditional Chinese medicine professor Wu Baiping of institute tell the reporter, he found over thousands of routine AIDS patient and virus carrier's clinical treatment in African, European, tens countries and regions, America by more than 10 year, the Chinese medicine that comprises acupuncture can suppress duplicating, improve body immunity, alleviating chemicals toxic and side effect and therapy apparatus opportunistic infections of virus.Wu Baiping says in this AIDS combination of Chinese tradiational and Western medicine diagnosis and treatment new development meeting that Hangzhou Sixth People's Hospital carries out, and among the HIV patient of his contact, all not morbidities of 10 years even 20 years arranged under traditional Chinese medical science supplemental treatment; 600 plurality of Chinese have also been collected from China by Cornell Univ USA, and confirm that wherein 31 kinds have certain anti-AIDS toxic action.The newest research results that branch school, California, USA university Los Angeles AIDS research association announces recently shows,---TAT2, researcher find that TAT2 tackles the main arch-criminal of the AIDS---effective means of " lymphocyte killer " (killer T-cells) that comprises a kind of special chemical substance in the Chinese herbal medicine astragalus.The Radix Astragali is expected to replace traditional treating AIDS mode---antiretroviral therapy, becomes the main mode of treatment AIDS.The American Studies personnel also point out in addition, and the Radix Astragali can also be treated other disease of immune system, especially viral infection and chronic disease are had special effect.
AIDS is as a global great difficult problem that jeopardizes the human life, and nearly 30 years, physianthropy circle carried out exploring many times, does not all find the method and the vaccine of radical cure AIDS, and all therapeutic schemes all can not obtain satisfied curative effect.
Summary of the invention
At the problems referred to above of prior art,, the invention provides a kind of health food that improves immune function and treating Aids by dietotherapy and preparation method thereof according to the principle of integration of drinking and medicinal herbs.This health food mainly contains seven flavor Chinese medicine and multiple nutrients materials; bioactivator wherein; as polysaccharide, cordycepin, biological flavone, reactive protein, saponin(e, vitamin, amino acid and mineral matter etc.; can fully replenish the required special dietary material of body; improve body resistance against diseases comprehensively; protection and raising immunologic function; distinctive activated protein confrontation HIV has special inhibition killing action; make get well fast level even can treatment of AIDS of patient, and do not find toxic and side effect as yet.
For achieving the above object, the present invention includes following technical scheme:
A kind of dietotherapy improves the health food of immune function and treating Aids, and it is made up of with auxiliary material and following traditional Chinese medicine ingredients food:
Cordyceps sinensis, 3～20 weight portions;
Honeysuckle, 10～16 weight portions;
Cordate houttuynia, 10～16 weight portions;
The red sage root, 10～16 weight portions;
Ginkgo nut, 13～20 weight portions;
Dried orange peel, 13～20 weight portions;
Aloe, 3～20 weight portions.
Aforesaid health food, preferably, described traditional Chinese medicine ingredients is as follows:
Cordyceps sinensis, 3～10 weight portions;
Honeysuckle, 10～16 weight portions;
Cordate houttuynia, 10～16 weight portions;
The red sage root, 10～16 weight portions;
Ginkgo nut, 13～20 weight portions;
Dried orange peel, 13～20 weight portions;
Aloe, 10～20 weight portions.
Aforesaid health food, preferably, described traditional Chinese medicine ingredients is as follows:
Cordyceps sinensis, 3.33 weight portions;
Honeysuckle, 13.33 weight portions;
Cordate houttuynia, 13.33 weight portions;
The red sage root, 13.33 weight portions;
Ginkgo nut, 16.67 weight portions;
Dried orange peel, 16.68 weight portions;
Aloe, 15 weight portions.
On the other hand, also a kind of dietotherapy of the present invention improves the health food of immune function and treating Aids, and it is made up of with auxiliary material Chinese medical extract and food, and this Chinese medical extract is made by following raw material:
Cordyceps sinensis, 3～20 weight portions;
Honeysuckle, 10～16 weight portions;
Cordate houttuynia, 10～16 weight portions;
The red sage root, 10～16 weight portions;
Ginkgo nut, 13～20 weight portions;
Dried orange peel, 13～20 weight portions;
Aloe, 3～20 weight portions.
Aforesaid health food, preferably, described Chinese medical extract is made by following raw material:
Cordyceps sinensis, 3～10 weight portions;
Honeysuckle, 10～16 weight portions;
Cordate houttuynia, 10～16 weight portions;
The red sage root, 10～16 weight portions;
Ginkgo nut, 13～20 weight portions;
Dried orange peel, 13～20 weight portions;
Aloe, 10～20 weight portions.
Aforesaid health food, preferably, described Chinese medical extract is made by following raw material:
Cordyceps sinensis, 3.33 weight portions;
Honeysuckle, 13.33 weight portions;
Cordate houttuynia, 13.33 weight portions;
The red sage root, 13.33 weight portions;
Ginkgo nut, 16.67 weight portions;
Dried orange peel, 16.68 weight portions;
Aloe, 15 weight portions.
Aforesaid health food, preferably, described food is selected from monose, oligosaccharides, compound sugar, polysaccharide, starch, coarse cereals powder, Vegetable powder, bean powder, milk powder, protein, amino acid, trace element, vitamin, flavor enhancement, dispersant, emulsifying agent, anticorrisive agent and/or water with auxiliary material.
Aforesaid health food, preferably, described food auxiliary material is sucrose, starch, vitamin C and/or protein.
Aforesaid health food, preferably, described amino acid is selected from tryptophan, threonine, methionine, valine, lysine, leucine, isoleucine, phenylalanine, arginine and histidine.
Aforesaid health food, preferably, described protein is lactalbumin or soybean protein.
Aforesaid health food, preferably, the weight of described sucrose is the 3-5% of described Chinese medical extract total amount, the weight of starch is 1～3% of described Chinese medical extract total amount, the weight of protein is 30～40% of described Chinese medical extract total amount, and ascorbic weight is the 0.2-0.4% of described Chinese medical extract total amount.
Aforesaid health food, wherein, the preparation method of described Chinese medical extract is as follows:
Take by weighing each bulk drug by weight, boiling 2～3 hours, the water yield that is added is 1～1.5 times of bulk drug gross weight; 60～80 ℃ of decompressions are steamed down and are removed moisture, 40～50 ℃ dry 2-4 hour.
Another aspect the invention provides the preparation method of aforesaid health food, and this method comprises the steps:
Take by weighing each bulk drug by weight, boiling 2～3 hours, the water yield that is added is 1～1.5 times of bulk drug gross weight; 60～80 ℃ of decompressions are steamed down and are removed moisture to paste, are cooled to 30～35 ℃, add auxiliary material and mix; 40～50 ℃ dry 2-4 hour, make particle.
The preparation method of aforesaid health food, wherein, described auxiliary material can be sucrose, starch, vitamin C and/or protein.
The preparation method of aforesaid health food, wherein, the weight of described adding sucrose is the 3-5% of described paste.
Again on the one hand, the present invention also provides a kind of dietotherapy to improve the health food of immune function and treating Aids, and it prepares according to aforesaid method.
Beneficial effect of the present invention: health food of the present invention is to set upright reinforcing; qi and activate blood circulation; hold concurrently with clearing heat and detoxicating; dispeling the wind, it is evil in the principle component design to loose, and wherein contains multiple bioactivator, as polysaccharide, cordycepin, biological flavone, reactive protein, saponin(e, vitamin, amino acid and mineral matter etc.; can fully replenish the required special dietary material of body; improve body resistance against diseases, protection and raising immunologic function have special inhibition killing action to HIV comprehensively.Result of study shows, takes the appetite that health food of the present invention can improve the patient, and the state of making the life better reduces various complication, and without any bad reaction.The particularly not good remarkable minimizing of patient's infection of the upper respiratory tract, headache, pruitus, diarrhoea, cough and physical efficiency.This health food can strengthen lymphocyte CD
3 +, CD
4 +With the multiplication capacity of WBC, and to reducing virus load positive effect is arranged, the absolute virus load of part patient reduces, and reaches the level that can not detect.
Description of drawings
Fig. 1 is placebo and health food group CD
4 +The cell average counter.
The specific embodiment
Researcher of the present invention relates generally to lung at the pathology of AIDS, spleen, the pathogenesis that kidney three is dirty, according to Chinese traditional treatment principle " reinforcing the mother-organ to treat deficiency; rush down its son actually ", mend female: nourishing liver and kidney (nourishing the kidney and the liver), reinforcing earth to generate metal (tonifying the spleen and lung), facilitating fire for tonifying the spleen (warming kidney and strengthening spleen), mutual generation between metal and water (grow lung and support kidney), rush down son: the real removing the heart-fire of liver, the real spleen that rushes down of the heart, lung is real to rush down kidney, to set upright reinforcing, qi and activate blood circulation, hold concurrently with clearing heat and detoxicating, the diffusing evil principle component design that is that dispels the wind is selected Cordyceps sinensis for use, honeysuckle, cordate houttuynia, the red sage root, ginkgo nut, dried orange peel and the combination of aloe seven flavor medicine thing are in conjunction with various nutrients, thereby can improve patient's autoimmunity, effectively play treatment, the effect that prevents AIDS.The brief introduction of seven flavor medicine material effect is as follows:
Cordyceps sinensis: nature and flavor are sweet, and are flat.Effect: invigorate the lung and the kidney hemostasis and phlegm.Cure mainly: chronic cough void is breathed heavily, the labor spitting of blood of coughing, impotence and seminal emission, soreness of waist and knee joint.Pharmacological action: 1. regulate function of immune system.2. antitumor.3. improve cellular energy, antifatigue.4. adjusting cardiac function.5. adjusting liver function.6. regulate the respiratory system function.7. adjusting renal function.8. adjusting hematopoiesis function.9. adjusting blood fat.10. antifatigue effect.
Honeysuckle: it is sweet to distinguish the flavor of; Cold.Return lung; The stomach warp.Effect cures mainly: clearing heat and detoxicating.The warm disease heating; Toxic-heat and blood stasis; The carbuncle furunculosis that swells; Larynx numbness and multiple infectious diseases.Pharmacological action: 1. antibacterial action: various bacteria (typhoid bacillus, paratyphosum Bacterium, Escherichia coli, proteus, Pseudomonas aeruginosa, Bordetella pertussis, comma bacillus and staphylococcus, streptococcus, Diplococcus pneumopniae, meningococcus etc.) is all had inhibitory action external.Honeysuckle has some inhibitory action external to the Bacillus tuberculosis.2. anti-inflammatory and refrigeration function.3. the function that strengthens the defense effect.4. central excitation effect.5. effect for reducing blood fat.6. antiendotoxin.
Cordate houttuynia: the nature and flavor suffering is slightly cold.Function cures mainly: clearing heat and detoxicating, and the carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia.Be used for the lung carbuncle pyemesis, the phlegm heat panting is coughed, hot dysentery, and heat is drenched, carbuncle sore tumefacting virus.Pharmacological action: 1. antibacterial action: the active ingredient decanoy acetaldehyde has obvious inhibitory action in vitro test to micrococcus catarrhalis, Bacillus influenzae, pneumococcus, staphylococcus aureus, and is then relatively poor to shigella dysenteriae, Escherichia coli, typhoid bacillus.2. antivirus action.3. diuresis.4. other effect: cordate houttuynia also has effects such as analgesia, hemostasis, inhibition serous secretion, promotion regeneration.
The red sage root: the nature and flavor hardship is slightly cold.The thoughts of returning home, Liver Channel.Effect: promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, the cool blood carbuncle that disappears, the relieving restlessness that clears away heart-fire, nourishing blood and tranquilization.Cure mainly: irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Ginkgo nut: nature and flavor are sweet, and hardship is puckery, and property is flat, mild toxicity.Function cures mainly: the gas of astringing the lung, relieving asthma and cough only is with turbidly, dwindles just.Control asthma, phlegm is coughed, leukorrhea, gonorrhoea, seminal emission, gonorrhoea, frequent urination.Pharmacological action: 1. antibacterial action, gingko meat, gingko juice, bilobol especially have inhibitory action to Bacillus tuberculosis and bacillus tuberculosis bovis during the ginkgolic acid in vitro test.2. to the effect of respiratory system, the gingko ethanol extract is injected to mouse peritoneal, and the phenol red excretion of respiratory tract is increased, and phlegm-dispelling functions is seemingly arranged.3. to the effect of the circulatory system, bilobol 500mg/kg has of short duration hypotensive effect to rabbit.4. to measured by esr technique, ginkgo nut exosper water soluble ingredient can be removed the superoxide radical that xanthine oxidase system produces in the presence of aerobic, suppresses chemiluminescence.
Dried orange peel: nature and flavor hardship, suffering, temperature.Function cures mainly: regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.Be used for chest gastral cavity turgor, food is few vomits and diarrhoea coughing with a lot of sputum.Clinical practice: 1. be used for diseases such as fullness and oppression of chest and abdomen.2. be used for that damp retention in middle-jiao, gastral cavity abdomen ruffian expand, have loose bowels in the loose stool, and phlegm disease such as cough more.3. be used for that insufficiency of the spleen diet reduces, indigestion, and disease such as n and V.
Aloe: the nature and flavor hardship, cold.Function cures mainly: removing heat from the liver, defaecation.Be used for constipation, infantile malnutrition, infantile convulsion; Control wet tinea outward.Pharmacological action: 1. discharge function: various aloe plants all contain anthraquinone derivative, especially aloin; These contain the anthracene glycocide will emit competence exertion excitant discharge functions such as archen in intestinal tube.2. treatment wound.3. antitumaous effect: 1: 500 alcohol extract of aloe extract, can suppress the growth of S-180 and EC in vivo; From extract, isolate an almost pure material higher antitumaous effect is arranged.
Cordyceps sinensis is monarch drug in a prescription in the above-mentioned prescription, and all the other are ministerial drug.The Cordyceps sinensis effect is to set upright reinforcing, has qi-restoratives and decreases, and beneficial vital essence, kidney-reinforcing Yang-strengthening, tonifying lung is relievingd asthma, and relieving cough and asthma function is used to promote the human immunological competence.The content of Cordyceps sinensis accounts for 3% o'clock of Chinese medicine gross weight, has had curative effect, increases better efficacy with its content, because this medicine price is higher, can adjust its dose according to actual conditions, is preferably the 3-20% that accounts for the Chinese medicine total amount, more preferably accounts for the 3-10% of Chinese medicine total amount.Honeysuckle effect is clearing heat and detoxicating, the main component chlorogenic acid, have clearing heat and detoxicating, the effect of dispelling wind and heat from the body.Cordate houttuynia effect is clearing heat and detoxicating, have clearing heat and detoxicating, the carbuncle that disappears apocenosis, the inducing diuresis for treating strangurtia effect is share with honeysuckle and can be played the purpose that synergy reaches synergy.Red sage root effect is promoting blood circulation and removing blood stasis, and main component is a danshensu, tanshinone.Has promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, the cool blood carbuncle that disappears, the relieving restlessness that clears away heart-fire, nourishing blood and tranquilization.Danshensu has promoting blood circulation and removing blood stasis, and tanshinone has the effect that protects the liver.The effect of ginkgo nut is promoting blood circulation and removing blood stasis, claims that again the gingko main component is ginkgolides and Total Ginkgo Flavone-Glycoides.Dried orange peel has benefiting action, and main component is an aurantiamarin, has regulating qi-flowing for strengthening spleen, in the accent, and eliminating dampness, the effect of reducing phlegm.The effect of aloe is the heresy of loosing, and its main component is an aloin, and effect has relieving constipation by purgation, clearing liver-fire.Aloe has the protective effect of pair cell tissue and the tax palingenesis alive of damaged cell, and germ has resistivity in the polysaccharide confrontation body in the aloe, and gives the human body premunition, reaches the purpose of fundamentally improving physique.Tinctura aloes is the very strong material of antibiotic property, has the effect of direct sterilization, compares even betterly with antibiotic, and it can not produce the pair cell drug resistance, and can also kill the drug-resistant bacteria because of using antibiotic to produce effectively.Because aloe has the effect under rushing down, can according to circumstances suitably reduce its consumption for the diarrhoea patient, preferred dose is the 3-20% that accounts for the Chinese medicine gross weight, more preferably accounts for the 10-20% of Chinese medicine total amount.
Health food of the present invention also can comprise various edible nourishing agent, additive etc.Specifically comprise for example monose, oligosaccharides, compound sugar, polysaccharide, starch, coarse cereals powder, Vegetable powder, bean powder, milk powder, amino acid, trace element, vitamin, flavor enhancement, dispersant, emulsifying agent, anticorrisive agent and/or water.
Amino acid comprises tryptophan, threonine, methionine, valine, lysine, leucine, isoleucine, phenylalanine, arginine and/or histidine.Can add each seed amino acid separately, also can use for example natural plants such as soybean protein, lactalbumin, animal protein, its addition can be with reference to human body required intake every day.
Wherein vitamin can comprise vitamin A, vitamin D
3, vitamin E, vitamin K
3, Cobastab
1, Cobastab
2, nicotinic acid, pantothenic acid, ester attitude VC, choline, Cobastab
6, folic acid, biotin or Cobastab
12, its addition can be with reference to human body required intake every day.
Trace element can comprise zinc, manganese, iron, copper, cobalt, iodine or selenium, and its addition can be with reference to human body required intake every day.
Flavor enhancement, dispersant, emulsifying agent and anticorrisive agent can adopt the commercially available product that meets food hygienic standard.
Below by the specific embodiment the technology of the present invention content is further explained
The preparation (one) of embodiment 1 Chinese medical extract
(1) take by weighing each bulk drug prepared slices of Chinese crude drugs according to following component and consumption:
Cordyceps sinensis, 3.33 grams; Honeysuckle, 13.33 grams; Cordate houttuynia, 13.33 grams; The red sage root, 13.33 grams; Ginkgo nut, 16.67 grams; Dried orange peel, 16.68 grams; Aloe, 15 grams.
(2) decocting that each bulk drug is mixed and adds 1.5 times of medicine gross weights boiled 2.5 hours, and 70 ℃ of decompressions are steamed down and removed moisture, and 50 ℃ of dryings 3 hours promptly obtain Chinese medical extract.
The preparation (two) of embodiment 2 Chinese medical extracts
(1) take by weighing each bulk drug prepared slices of Chinese crude drugs according to following component and consumption:
Cordyceps sinensis, 15 grams; Honeysuckle, 15 grams; Cordate houttuynia, 10 grams; The red sage root, 16 grams; Ginkgo nut, 13 grams; Dried orange peel, 14 grams; Aloe, 20 grams.
(2) decocting that each bulk drug is mixed and adds 1 times of medicine gross weight boiled 3 hours, and 70 ℃ of decompressions are steamed down and removed moisture, and 45 ℃ of dryings 3 hours promptly obtain Chinese medical extract.
The preparation (three) of embodiment 3 Chinese medical extracts
(1) take by weighing each bulk drug prepared slices of Chinese crude drugs according to following component and consumption:
Cordyceps sinensis, 10 grams; Honeysuckle, 10 grams; Cordate houttuynia, 15 grams; The red sage root, 10 grams; Ginkgo nut, 16.67 grams; Dried orange peel, 20 grams; Aloe, 10 grams.
(2) decocting that each bulk drug is mixed and adds 1 times of medicine gross weight boiled 3 hours, and 70 ℃ of decompressions are steamed down and removed moisture, and 40 ℃ of dryings 4 hours promptly obtain Chinese medical extract.
Embodiment 4 dietotherapies improve the preparation () of immune function and treating Aids health food
(1) take by weighing each bulk drug prepared slices of Chinese crude drugs according to following component and consumption:
Cordyceps sinensis, 3.33 grams; Honeysuckle, 13.33 grams; Cordate houttuynia, 13.33 grams; The red sage root, 13.33 grams; Ginkgo nut, 16.67 grams; Dried orange peel, 16.68 grams; Aloe, 15 grams.
(2) each bulk drug is mixed also boiling 2.5 hours, the water yield that is added is 1.5 times of bulk drug gross weight; 70 ℃ of decompressions are steamed down and are removed moisture to paste, are cooled to 30～35 ℃, add sucrose and mix, and the weight that adds sucrose is 5% of paste; 50 ℃ of dryings 3 hours are made particle.
Embodiment 5 dietotherapies improve the preparation (two) of immune function and treating Aids health food
(1) take by weighing each bulk drug prepared slices of Chinese crude drugs according to following component and consumption:
Cordyceps sinensis, 5 grams; Honeysuckle, 13.33 grams; Cordate houttuynia, 13.33 grams; The red sage root, 13.33 grams; Ginkgo nut, 16.67 grams; Dried orange peel, 16.68 grams; Aloe, 8 grams.
(2) each bulk drug is mixed also boiling 2 hours, the water yield that is added is 1.5 times of bulk drug gross weight; 70 ℃ of decompressions are steamed down and are removed moisture to paste, be cooled to 30～35 ℃, adding sucrose, starch, vitamin C and lactalbumin mixes, the weight that adds sucrose is 5% of paste, the weight of starch is 2% of paste, the weight of lactalbumin is 35% of paste, and ascorbic weight is 0.3% of paste; 50 ℃ of dryings 3 hours are made particle.
Embodiment 6 tests of pesticide effectiveness
One, sample collection
Determine that with Kenya AIDS association the HIV of Westbound, Nairobi carries the experimenter, the experimenter is the sex that HIV-1 infects, and the age is in 18-50 year.Now according to body mass index with experimenter's rough segmentation group, the BMI index is 22～30kgm
-2Tell two groups at random in the group, take placebo for first group, second group of health food of taking embodiment 4 preparations.Above-mentionedly respectively organize medication and adopt the double blinding design, all establish blind patient, testing crew and laboratory.
Two, give mode
Give placebo every day three times, each 15g to first group; To second group of health food every day that gives embodiment 4 preparation three times, each 15g; Give 22 months continuously.
Three, test procedure and method
(1) normal experiment
Blood sample is centrifugal, takes out serum 5mL, and sample places-80 ℃ of preservations, and (centre for public health research CPHR) analyzes to send nutrition research department, public health research center.
(2) special test
The first, infection state and HIV-1RNA virus load investigation: 4mL EDTA anticoagulant send KEMRI analysis center CVR.Confirm patient's HIV state and virus load by the ELISA rapid analysis, adopt the Brabched DNA kit (BioCat company) of RNA quantitative analysis tech.
The second, finish CD in KEMRI biotechnology research portion (CBRD)
4 +, CD
8 +With the NK cell count, 5mL EDTA anticoagulated blood, BD company flow cytometer is analyzed.
Three, whole blood adopts the whole blood EDTA anti-freezing of 2mL, analyzes at CPHR.
Four, liver function analysis, antivacuum blood sampling 4mL whole blood was taken the back 12nd month, analyzed at CPHR, adopted the Sigma kit to analyze at Hitachi's 410 photometers and flame photometer.
Four, experimental result
1. experimenter's basic condition and overall assessment
Table 1
(annotate: n is each group tester number, and each data unit is %)
It is as shown in table 1 that overall assessment and virus detect the result, tried the patient for these two groups in the process of the test and in treatment intervention back detection, although the score value of WHO is all lower, most people's health all has better improvement.The overall assessment result shows, take embodiment 4 health foods after 22 months score value the higher person be elevated to 80% from original 19%, virus does not detect ratio and rises to 45% from 13%.
2. the AIDS experimenter is in experiment beginning 12nd month performance and symptom
Table 2
(annotate: n is each group tester number, and each data unit is %)
The result is as shown in table 2, and the person reduces to 0% from 10.5% to have the symptom of diarrhea at 12nd month that takes among the visible patient; Infection of the upper respiratory tract person reduces to 0% from 10.5%; The headache patient reduces to 4.0% from 15.8%; Fash patient reduces to 4.2% from 21.1%; Feel that weak person reduces to 0% from 15.8%; There is 85.7% patient to improve a poor appetite.
3. clinical nutriology and hematological indices
Table 3
(annotate: n is each group tester number, and the P value is represented the declining indicator of credible result degree.)
Nutrition and immunologic function index that table 3 has provided the experimenter change.Two groups of experimenter's body temperature unanimities (P=0.804) during on-test, the health food group was lower than comfort group in the 22nd month, illustrated to take after the health food AIDS virus is caused that health immune response heating phenomenon has remarkable result.Health food group patient B MI value has improved 0.6, and the change of placebo body weight is not remarkable.The blood data aspect, two groups of lymph countings similar (P=0.207) during on-test, health food group average counter median was apparently higher than comfort group (P=0.003) in 22nd month, this prompting is passed through to strengthen lymphocytic propagation after taking health food, thereby the skeptophylaxis system resists virus to play a role.Similarly, 22nd month health food group significantly increases (P=0.007) than comfort group WBC counting.
4. immunology and virology index
Table 4
(annotate: n is each group tester number, and the P value is represented the declining indicator of credible result degree.)
The mean value of health food group and placebo experimenter amynologic index is all more consistent, and data see Table 4.CD
3 +The initial difference of cell less (P=0.096), health food group significantly increased (P=0.011) at 22nd month.22nd month health food group CD
8 +Cell count is increased (P=0.036) than placebo is remarkable.Two groups of CD
4 +Cell count each time point in early days is similar substantially, and very high numerical value (P=0.175), two groups of CD appear in the health food group in the time of 22nd month
4 +The cell average counter is seen Fig. 1.An interesting trend is, the health food group has occurred one and increased effect, and as previously mentioned, the average virus load of health food group reaches the ratio that can't check significantly to be increased, and placebo is quite different.The logarithmic mean value of the described virus load of table 4 too, comfort group increase and decrease is slight, the health food group is to continue to reduce, although the reduction amount does not reach conspicuousness as yet, this will consider the reason that sample size is less.
5. intervening measure safety analysis
Table 5 liver function analysis (IQR) of two groups in the time of 12nd month
(annotate: n is each group tester number, and the P value is represented the declining indicator of credible result degree.)
Carried out comprehensive liver function at 12nd month and detected, data show health food group experimenter liver function all normal (seeing Table 5), illustrate that it is to body nonhazardous, safety.
Embodiment 7 clinical typical cases
One, BETTY BOOP, woman, Botswana, the HIV positive
Weak, alopecia appears several years ago and symptom such as lose weight.Find the HIV positive in hospital in April, 2006; after the HAART treatment, improve little; phenomenon such as vomiting also occurred, have horrible nightmares; its life has been caused very big influence, felt blue, alopecia is very serious; do not feel like eating; rather disappointed to living, conscious very tired out, through regular meeting friend is said and oneself will die.
Agree through the patient in January, 2008, abandon the cocktail treatment, begin to take embodiment 1 described Chinese medical extract, every day three times, each 15g.After taking one month, appetite is gradually good, and skin has greatly improved, and health is taking a turn for the better always, and tired out and other malaise symptoms have all disappeared.And do not have any side effect.
In February, 2008, the doctor paid a return visit her, she is very willing to talk with the doctor, all malaise symptoms have all disappeared before her, full of hope to living, do not catch a cold, not headache, her state of mind is fine, and skin is fine glossy, appetite is fine, body weight is also very normal, and she has also recovered normal work, usually seldom can mention this disease, because she is imperceptible any discomfort is arranged, January do check Shi doctor very surprised tell her: " you are still positive, but your CD4 is dry straight, your virus follow the trail of less than ".
Two, Nan Qian. Ai Furui, woman, the U.S., the HIV positive
In December, 1999 aids infection, after suffer from hepatitis again, not only original symptom is not improved after HAART treatment, continues to increase the weight of, and many side effects occurred, and its life has been caused very big influence, and cisco unity malfunction.
Agree through the patient in July, 2007, abandon the cocktail treatment, begin to take embodiment 2 described Chinese medical extracts, every day three times, each 15g.
After taking this product, the very fast alleviation of the AIDS symptom before her disappears, and the side effect that produces because of HAART also disappears, and does not have any side effect.
After one month she is paid a return visit, she has disappeared at all AIDS symptoms, and her state of mind is fine, and appetite and body weight are all very normal, can be Myself to want the thing done, feels in the pink of condition.
Three, Mrs Zhao, China, 49 years old, the HIV positive
Find AIDS during generaI investigation in 2003, morbidity first in 2005, persistent fever is surplus January, DeGrain after various corresponding treatments, after take antiviral drugs after January, heating is gone down, but symptoms such as dizzy, nauseating appear subsequently, because of being impatient at the discomfort drug withdrawal.This take how to have the first half always weak, can not dry weight muscular labor, pale complexion, appetite is poor, one day two meal is often had a stomach upset and pain after the dinner.Begin to take embodiment 3 described Chinese medical extracts in February, 2009, every day three times, each 15g, report shows the HIV positive, take one month after, have rosy cheeks, weak disappearance can be free movable, upstairs do not breathe heavily, appetite is improved, and the three meals in a day of can taking food do not have uncomfortable after the meal, virus and CD4 result detect and meet drug action mechanism, August, report showed, CD4 raises obviously, and virus load drops to detection less than level.This Ms represents that her quality of life has obtained raising, and does not have harmful effect.
Four, Mr. Guo, China, 52 years old, the HIV positive
Discovery in 2002 suffers from AIDS, takes antiviral drugs less than two months in 2004, cuts out because of uncomfortable, often has the difficulty of breathing in the past, fatigue and weak, and often flu and difficult healing, there is fash the multi-section position on one's body, and itch is shown effect repeatedly and is not healed unbearably.Begin to take embodiment 5 described health foods in February, 2009, every day three times, each 20g, take two weeks, the disappearance of breathing hard, strong upstairs, muscle power is obviously improved, and flu is not arranged, and fash begins healing, itch disappears, and the fash complete obiteration is had rosy cheeks when taking two months, muscle power is strong, can carry out suitable physical exertion, the demonstration of reporting the result, CD4 promotes significantly, and virus load drops to detection less than level.This user represents that oneself is very lucky, the effect of this health food be other medicines can not than, he has realized the miraculous effects of this health food really, fash is very painful, he has freed finally now.
Claims (7)
1. the health food of a dietotherapy raising immune function and treating Aids is characterized in that it is made up of with auxiliary material Chinese medical extract and food, and this Chinese medical extract is made by decocting method by following raw material:
Cordyceps sinensis, 3～20 weight portions;
Honeysuckle, 10～16 weight portions;
Cordate houttuynia, 10～16 weight portions;
The red sage root, 10～16 weight portions;
Ginkgo nut, 13～20 weight portions;
Dried orange peel, 13～20 weight portions;
Aloe, 3～20 weight portions.
2. health food according to claim 1 is characterized in that, described Chinese medical extract is made by decocting method by following raw material:
Cordyceps sinensis, 3～10 weight portions;
Honeysuckle, 10～16 weight portions;
Cordate houttuynia, 10～16 weight portions;
The red sage root, 10～16 weight portions;
Ginkgo nut, 13～20 weight portions;
Dried orange peel, 13～20 weight portions;
Aloe, 10～20 weight portions.
3. health food according to claim 2 is characterized in that, described Chinese medical extract is made by decocting method by following raw material:
Cordyceps sinensis, 3.33 weight portions;
Honeysuckle, 13.33 weight portions;
Cordate houttuynia, 13.33 weight portions;
The red sage root, 13.33 weight portions;
Ginkgo nut, 16.67 weight portions;
Dried orange peel, 16.68 weight portions;
Aloe, 15 weight portions.
4. according to each described health food among the claim 1-3, it is characterized in that described food is selected from monose, oligosaccharides, compound sugar, polysaccharide, starch, coarse cereals powder, Vegetable powder, bean powder, milk powder, amino acid, trace element, vitamin, flavor enhancement, dispersant, emulsifying agent, anticorrisive agent and/or water with auxiliary material.
5. according to each described health food among the claim 1-3, it is characterized in that the preparation method of described Chinese medical extract is as follows:
Take by weighing each bulk drug by weight, boiling 2～3 hours, the water yield that is added is 1～1.5 times of bulk drug gross weight; 60～80 ° of C decompression is steamed down and is removed moisture, dry 2-4 hour of 40～50 ° of C.
6. according to the preparation method of each described health food among the claim 1-3, it is characterized in that this method comprises the steps:
Take by weighing each bulk drug by weight, boiling 2～3 hours, the water yield that is added is 1～1.5 times of bulk drug gross weight; 60～80 ° of C decompressions are steamed down and are removed moisture to paste, are cooled to 30～35 ° of C, add auxiliary material and mix; Dry 2-4 hour of 40～50 ° of C make particle.
7. the health food of a dietotherapy raising immune function and treating Aids is characterized in that, it is method preparation according to claim 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101196392A CN102630939B (en) | 2012-04-20 | 2012-04-20 | Health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101196392A CN102630939B (en) | 2012-04-20 | 2012-04-20 | Health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102630939A CN102630939A (en) | 2012-08-15 |
| CN102630939B true CN102630939B (en) | 2013-07-31 |
Family
ID=46615656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101196392A Expired - Fee Related CN102630939B (en) | 2012-04-20 | 2012-04-20 | Health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102630939B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857248A (en) * | 2015-03-25 | 2015-08-26 | 广州如源生物科技有限公司 | AIDS treating immunoloregulation composition and preparation method thereof |
| CN104719898A (en) * | 2015-03-25 | 2015-06-24 | 广州如源生物科技有限公司 | Health food for treating acquired immune deficiency syndrome and preparation method thereof |
| CN105360837A (en) * | 2015-12-04 | 2016-03-02 | 山东翊弘生物科技有限公司 | Vinegar-egg regression solution and preparation method thereof |
| CN108013450A (en) * | 2017-12-01 | 2018-05-11 | 绵阳正耀久生物科技有限公司 | It is a kind of that there are the health products for improving immune function |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101077406A (en) * | 2006-05-26 | 2007-11-28 | 张晋玮 | Traditional Chinese medicine for preventing and treating acquired immuno-deficiency syndrome and its preparing process |
| CN101015672A (en) * | 2006-08-18 | 2007-08-15 | 陈培生 | Preparation of traditional Chinese medicine biological agent for treating AIDS |
-
2012
- 2012-04-20 CN CN2012101196392A patent/CN102630939B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN102630939A (en) | 2012-08-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102048933B (en) | Chinese medicinal composition for treating infantile diarrhea and preparation method thereof | |
| CN102205107B (en) | Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof | |
| CN102362970B (en) | Traditional Chinese medicinal composition with gastrointestinal tract improvement function and preparation technology thereof | |
| CN102630939B (en) | Health-care food for treating AIDS (acquired immunodeficiency syndromes) by increasing immunity through dietary therapy and preparation method thereof | |
| CN114042126B (en) | Traditional Chinese medicine composition for ascending clear, eliminating turbid, promoting diuresis, benefiting qi, losing weight and reducing fat and preparation method thereof | |
| CN104757669A (en) | Blood pressure and blood lipid lowering health drink and preparation method thereof | |
| CN101015618A (en) | Health-care wine with sleeping improving and beauty functions and its preparing process | |
| CN101904501B (en) | Functional food for relieving fatigue and preparation method thereof | |
| CN103977372A (en) | Traditional Chinese medicine additive used for treating porcine epizootic diarrhea and preparing method thereof | |
| CN104547961B (en) | A kind of Chinese medicine composition for treating gall stone | |
| CN103977390B (en) | A kind of preparation method and its usage of ginger onion medicated wine composition | |
| Sharma et al. | Adaptogens: new age healing gems for physical wellbeing | |
| CN102641403B (en) | Traditional Chinese medicine composition for treating and/or preventing Acquired Immune Deficiency Syndrome (Aids) and preparation method thereof | |
| US7381430B2 (en) | Pharmaceutical composition comprising a combination of Chinese traditional medicines | |
| CN114748603A (en) | Medicine-food homologous composition for preventing and treating new coronavirus pneumonia variation or compound yang and application | |
| CN112316051B (en) | Traditional Chinese medicine composition for nourishing blood and reducing phlegm as well as traditional Chinese medicine preparation, preparation method and application thereof | |
| CN111298020B (en) | Traditional Chinese medicine composition with anti-fatigue effect and preparation method and application thereof | |
| CN101024015B (en) | Caroprocaprae Gutturosae, ginseng, lycium extract for treating scapulohumeral periarthritis, arthromyodynia, impotence, prospermia and sub-health | |
| CN100509043C (en) | Chinese medicine composition for eliminating drug addication | |
| CN1169315A (en) | Immunity-regulating health-care tea | |
| CN109620913B (en) | Composition for preventing and/or treating obesity and hyperglycemia | |
| CN106376930A (en) | Nutritional medicinal diet powder for treating chronic diarrhoea and preparation method thereof | |
| JPH11158077A (en) | Composition having alleviating effect on stress | |
| KR101930145B1 (en) | Fasting supplement composition | |
| CN112641898A (en) | Medicine for quickly losing weight |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: GUANGZHOU RUYUAN BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: LU ZIYUN Effective date: 20140331 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20140331 Address after: 510080, 27 floor, Xin Yu building, 81 agriculture and forestry road, Yuexiu District, Guangdong, Guangzhou Patentee after: GUANGZHOU RUYUAN BIOTECHNOLOGY Co.,Ltd. Address before: 510080, 27 floor, Xin Yu building, 81 agriculture and forestry road, Yuexiu District, Guangdong, Guangzhou Patentee before: Lu Ziyun |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130731 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |