CN1413727A - Composite medicine for radical curing AIDS - Google Patents
Composite medicine for radical curing AIDS Download PDFInfo
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- CN1413727A CN1413727A CN 02130603 CN02130603A CN1413727A CN 1413727 A CN1413727 A CN 1413727A CN 02130603 CN02130603 CN 02130603 CN 02130603 A CN02130603 A CN 02130603A CN 1413727 A CN1413727 A CN 1413727A
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Abstract
A composite medicine for radically treating AIDS is prepared from more than 30 Chinese-medicinal materials including propolis, water-soluble pearl powder, etc and 7 Western medicines including zinc gluconate, etc. Its advantages are high curative effect and no recurrence.
Description
Technical field:
The present invention relates to a kind of pharmaceutical composition that effects a radical cure acquired immune deficiency syndrome (AIDS), relate in particular to a kind of novel specific medicament compositions that can effect a radical cure the pure Chinese medicinal preparation of acquired immune deficiency syndrome (AIDS).The invention belongs to the Chinese medicine and pharmacy technical field.
Background technology:
The active drug of modern medicine treatment acquired immune deficiency syndrome (AIDS), the medicine series of first-elected " HAART ".
" HAART " is the acquired immune deficiency syndrome (AIDS) method preferably for the treatment of at present, taught in 1996 by Chinese American He Dayi to propose.This therapy is united use with 2 kinds of efabirenzs and a kind of albumen enzyme inhibitor, also claims highly active antiretroviral therapy.It can reduce the HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) carrying capacity in the blood, even drops to sensitive detecting method and also be difficult to find virus, thereby improves patient's clinical symptoms effectively, prolongs patient's life cycle.
" the chicken tail spills therapy " is why effective, is that ucleosides and non-nucleoside reverse transcriptase inhibitor can act on the early stage of HIV (human immunodeficiency virus) (Human Immunodeficiency Virus), and it directly is incorporated into reverse transcriptase, thereby stops the synthetic of vDNA, makes not reproducible of virus; And protease inhibitor acts on the later stage of HIV (human immunodeficiency virus) (Human Immunodeficiency Virus), the final stage of its blocking virus " assembling ".Like this, different types of drugs can both play inhibitory action in the morning that HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) is duplicated, late two phases, stops the rapid breeding of HIV (human immunodeficiency virus) (Human Immunodeficiency Virus).
Yet " HAART " also has its weak point.At first, it can not effect a radical cure acquired immune deficiency syndrome (AIDS), and medication all can not be removed and bonded HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) of cell DNA (deoxyribonucleic acid) and the virus in lymph node, nervous system of hiding in any case.Secondly, this Therapeutic Method is very complicated, and inappropriate medication may cause that persister takes place, and needs long-term prescription, in case drug withdrawal midway can cause the bounce-back of health inner virus, and not only involution but also development is arranged of the state of an illness, its result is even worse.Moreover, medicine also has a lot of side effect, as feel sick, vomiting, peripheral neuritis, erythra, anemia, myopathy, body fat are redistributed etc., so at present to " HAART " need of acquired immune deficiency syndrome (AIDS) patient in hospital through there being certain empirical physician guidance to carry out, be sure not blind application of any.What will propose at last is, China still needs now from these medicines of external import, and is very expensive, and its expense is used in the U.S. and needed 1～20,000 dollar approximately in 1 year.Concerning general acquired immune deficiency syndrome (AIDS) patient,, be difficult to bear as long-term prescription.
Adopt pure Chinese medicine or Chinese and western medical to combine and treat the prior art of acquired immune deficiency syndrome (AIDS), the most approaching with the present invention.Up to now, disclosed this type of patent application that can retrieve surpasses hundred, is exceeded 20 by what State Intellectual Property Office granted patent.(particulars provides separately)
Summary of the invention:
The object of the present invention is to provide a kind of high curative effect that can effect a radical cure acquired immune deficiency syndrome (AIDS), the short course of treatment, and the new drug that has no side effect of safety, for the mankind finally defeat a bit meagre strength of acquired immune deficiency syndrome (AIDS) contribution.
The object of the present invention is achieved like this: the technical program is formed by following drug matching:
Monarch drug: propolis 5%, aqueous fusion property Margarita powder 3%, ministerial drug: Lac regis apis 3%, Pollen Pini 3%, Cordyceps 3%, Ganoderma spore powder 2%.Adjuvant: Radix Ginseng 3%, the Radix Astragali 3%, the Rhizoma Atractylodis Macrocephalae 3%, Poria 3%, Rhizoma Dioscoreae 3%, the Radix Paeoniae Alba 3%, Radix Angelicae Sinensis 3%, XUANJU 3%, Cortex Cinnamomi 3%, Rhizoma Zingiberis 3%, Semen Cuscutae 3%, Fructus Ligustri Lucidi 3%, Herba Ecliptae 3%, the Rhizoma Anemarrhenae 3%, Cortex Phellodendri 3%, Rhizoma Coptidis 2%, Fructus Gardeniae 3%, Radix Trichosanthis 3%, Radix Paeoniae Rubra 3%, Radix Scrophulariae 3%, Radix Bupleuri 3%, Radix Curcumae 3%, the Radix Linderae 3%, Radix Et Rhizoma Rhei 2%, Semen Coicis 3%, Herba Artemisiae Scopariae 3%, Bi 3%, Herba Euphorbiae Helioscopiae 2%
In above-mentioned Chinese medicine preparation, add the Western medicine of following kind and quantity in per 10 days consumptions:
Misery 30 grams of glucose, succinic acid germanium 6 grams, DL methionine 20 grams, orotic acid 2 grams, thioctamide 0.8 gram, vitamin C 3 grams, silymarin 0.8 gram.
The side separates:
For science more, set forth more accurately, separate the idiom that not exclusively sticks to Chinese medicine with the below.
At first propolis and Margarita two flavor monarchs drug are explained in detail.
Owing to be subjected to the restriction of the scientific research degree of depth at that time and range, Chinese medicine ancient books and records up to now are too unilateral and abstract to records such as the nature and flavor of two flavor monarchs drug, effect.Below mainly explain in detail from the modern study angles of two flavor monarchs drug.
Propolis: property is flat, acrid in the mouth, sweet, little hardship, GUIXIN, pericardium, liver, spleen, lung meridian, effect: blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, anti-inflammation, viral infection resisting, antioxidation, two-ways regulation immune function of human body.
Modern study shows that propolis is rich in flavonoid (flavones) chemical compound.Kind surplus now the flavone compound of isolation identification has had 20 from propolis, wherein 5,7-dihydroxy-3,4-dimethyl flavone and 5-hydroxyl 4,7-dimethyl flavanone are the unique effective ingredient in the propolis.
According to domestic and international relevant pharmacology and clinical trial certificate up to now, Flavonoid substances mainly contains following physiological action to human body:
1, strengthens antiotasis, reduce vascular fragility and unusual permeability;
2, blood lipid regulation and cholesterol reducing;
3, reduce erythrocyte and hematoblastic gathering, reduce thrombosis, microcirculation improvement;
4, hepatoprotective is separated the liver poison, treatment acute, chronic hepatitis, liver cirrhosis and multiple toxic liver injury;
5, improve body immunity;
6, antiinflammatory, eliminate the phlegm, analgesic, the detumescence;
7, antibiotic, antiviral, antifungal, inhibition tumor;
8, antioxidation, defying age;
9, spasmolytic;
10, antiallergic;
11, the activity that suppresses certain enzyme;
12, strengthen cell membrane, activating cell.
Modern study shows that also propolis is rich in terpenes (terpennic series) chemical compound.Terpene compound is varied, also has diversified biological activity simultaneously.Radix Ginseng, the Radix Astragali, Radix Glycyrrhizae, Radix Bupleuri etc. all contain terpenoid substance, but all can not mention in the same breath with the unique quality of propolis on quality and quantity.
According to domestic and international relevant pharmacology and clinical trial certificate up to now, terpenoid substance mainly contains following physiological action to human body:
1, bactericidal antiphlogistic;
2, antipyretic-antalgic;
3, blood circulation promoting and blood stasis dispelling;
4, spleen reinforcing is good for the stomach;
5, repellent antipruritic;
6, expelling phlegm for arresting cough;
7, local anesthesia;
8, antitumor;
9, two-ways regulation blood glucose;
10, strengthen body immunity;
11, fragrance is pleasant.
Except flavone, terpenes two class important substance, propolis also is rich in the necessary several amino acids of biological existence, several kinds of mineral elements, vitamin B
1, vitamin B
6, vitamin E, vitamin A,, also have polysaccharide, enzyme, organic acid, quinones, lipid, aldehydes, phenols, ethers or the like.Propolis is rich in the so abundant complexity with physiology and pharmacological activity and unique composition just, has just given propolis extensively and the effect of mystery.(above " magical propolis therapy ") about the understanding of propolis is edited referring to " 95 " emphasis key scientific and technological projects propolis seminar of country
We combine domestic and international relevant pharmacology and clinical experiment experience up to now ourselves with the research practice of using propolis treatment acquired immune deficiency syndrome (AIDS), cancer, viral hepatitis, autoimmune disease, extensive and the magical effect of propolis is concluded, and mainly is following four large effects:
1, propolis is the best natural broad ectrum antibiotic of finding at present.(bactericidal antiphlogistic, antivirus action)
Lot of documents to the propolis antibacterial action proves again and again that all propolis has inhibition, killing action simultaneously to numerous antibacterials, fungus, virus, is a kind of natural wide spectrum antibiotics of preciousness both at home and abroad.Our research practice proves that also propolis has fabulous direct inhibition and killing action to HIV (human immunodeficiency virus) (HIV).(this point is not seen bibliographical information so far, belongs to the innovation category.)
The antibiotic effect of propolis is wide spectrum, efficient not only, and has no side effect, no pathogenic bacteria Drug resistance generation, and this is that the antibiotic of present any synthetic is incomparable.
2, propolis has two-way immunoregulation effect.
(1), immunological enhancement.
1988, people such as Scheller studies have shown that the hemolysis plaque that propolis extract can increase animal spleen index and splenocyte forms cell quantity, thereby have strengthened the function of bone-marrow-derived lymphocyte.
1992, people such as Dimov studies have shown that, propolis extract can activating macrophage, strengthens human body nonspecific immunity function.
We use Chinese medicinal formulae treatment the limited of acquired immune deficiency syndrome (AIDS) studies have shown that, adopt the prescription of propolis compatibility to compare with the prescription that does not adopt propolis, for T
4The increase of cell quantity, T
4/ T
8There is notable difference on the effects such as minimizing of the improvement of ratio, HIV quantity.(this point is not seen bibliographical information so far, belongs to the innovation category.)
(2), similar immunosuppressive action.
When the treatment modern medicine was referred to as autoimmune disease, doctor trained in Western medicine often adopted the cortical steroid immunosuppressant to carry out contraria.We use Chinese medicinal formulae therapy system lupus erythematosus, when autoimmune diseasees such as dry syndrome, limited studies have shown that, the curative effect that adopts propolis compatibility prescription is apparently higher than the prescription that does not adopt the propolis compatibility.(this point is not seen bibliographical information up to now, belongs to the innovation category.)
Can act on the immunologic function of human body simultaneously, " its deficiency of benefit " and " eliminating to treat the excess syndrome " are carried out simultaneously, and just right; Here it is, and propolis carries out the delicate place of two-ways regulation to immune function of human body.
3, propolis is a kind of Natural antioxidant of preciousness.(antioxidation)
As everyone knows, superoxide dismutase (SOD) is antioxidation, the founding father who removes free radical, and too much free radical then is the killer of human-body biological cell.
Studies have shown that the superfluous human body self immunologic function that significantly reduces of free radical comprises that more than 80 kind of disease of cancer is all closely related with free radical.
Studies have shown that propolis promptly has very strong oxidation resistance under 0.01%～0.05% concentration.Propolis extract can make the intravital superoxide dismutase of white mice (SOD) activity significantly improve.The antioxidation of propolis, the good efficacy of free radical resisting certainly will significantly improve the resistance against diseases of human body, have positive role in the free burial ground for the destitute undoubtedly for the reverse of acquired immune deficiency syndrome (AIDS).
4, improve blood circulation, microcirculatory good efficacy.
Medical research proves, hundreds of kind disease is all closely related with blood circulation, microcirculation disturbance, and the change of the change of blood constituent, hemorheological change, blood vessel wall situation is again the three big fundamentals that influence blood circulation, microcirculation situation.Blood circulation, microcirculation situation and immunologic function situation are closely related.
The multiple flavonoid that propolis is rich in, terpenoid substance both can blood fat reducing, cholesterol reducing thereby reverse the change of blood constituent, again can dilute blood, vessel softening, reduction vascular fragility and unusual permeability reverse the change of hemorheology and blood vessel wall situation.The comprehensive improvement of these three big fundamentals certainly will form the improvement of blood circulation, microcirculation situation, certainly will form the comprehensive improvement of immunologic function situation.
In sum, be exactly we why to be monarch's 4 big reasons with the propolis.
Margarita: cold in nature, sweet in the mouth, one-tenth, GUIXIN Liver Channel.Effect: the relieving palpitation arresting convulsion, liver heat removing removes nebula, the convergence granulation promoting.
Above Chinese medicine ancient books and records are still too unilateral abstract about the record of Margarita.
Modern study proves that the main component of Margarita is that calcium carbonate content is up to more than 92%; Also be rich in necessary for human body 20 various trace elements, as trivalent chromium, copper, vanadium, zinc, ferrum, manganese etc.; Also be rich in the whole aminoacid of necessary for human body, multivitamin (particularly contains VB
6, the vitamin B group that lacks of human body such as nicotinic acid, niacin amide), also contain the peculiar bioactive substance conchiolin of Margarita, Margarita peptide, taurine ...
The biological activity effect of various content is as follows substantially:
Calcium have vital movement second message,second messenger's title.
Manganese plays important synergism in the ossification that promotes calcium, can effectively prevent osteoporosis; Collaborative calcium is brought into play the effect of effective convulsion, tetany, epilepsy in the balance adjustment of nervus centralis function; Be the main active of the SOD of anti-superoxide radical injury in the cerebral tissue, also have and keep carbohydrate metabolism and the complete effect of pancreatic function.
Trivalent chromium and vanadium are working aspect adjusting carbohydrate metabolism and the oxidation of promotion steatolysis.Trivalent chromium is the active component of glucose tolerance factor, collaborative insulin performance effect.
Cobalt, the effect of collaborative calcium performance blood pressure regulating is a vitamin B
12Active component.
Ferrum with the cobalt synergism, promotes the synthetic of hemoglobin in hematopoiesis, improve hematochrome content, works the effect that nourishes blood.
Copper and zinc are " street cleaners " of free radical in the human body, are the main active of superoxide dismutase (SOD), can improve the metabolism intensity of human body, and the effect of removing brown fat element, face-beautifying and spot-removing is carried out and had to protection cell normal physiological activity; Zinc-copper ratio＜1, heart effect is protected in the blood pressure lowering that helps collaborative calcium.
Silicon, high-load silicon can stop the intestinal absorption of aluminum and other heavy metal ion, has the effect of senile dementia of preventing and heavy metal poisoning ...
Margarita not only is rich in necessary macroelement of above human body and trace element, and the proportionate relationship of each element is very delicate, be a kind of gold proportioning, very approaching with the content ratio of the when injected organism tissue composition of human body normal physiological state, (FAO) is very approaching with world standard.
We adopt Margarita compatibility Chinese medicinal formulae treatment comprise acquired immune deficiency syndrome (AIDS) various difficult and complicated illness studies have shown that Margarita has identical or similar effect with propolis aspect a lot, and complements one another, brings out the best in each other; Especially as if gratifying is that Margarita also has as above said two-way immunoregulation effect, and this effect is better than propolis.Here it is, and why we will select Margarita and propolis compatibility, are the reason of monarch drug altogether.
Margarita of the present invention is selected east superstar's water soluble Margarita ultrafine powder for use, and absorbance is more than 90%, and for common Margarita powder four times help bringing into play the effect of Margarita more.
Lac regis apis: property is flat, and sweet in the mouth is returned spleen, lung, large intestine channel, is product on the strengthening by means of tonics.
Pollen Pini: property is flat, and sweet in the mouth is returned spleen, lung, kidney channel, has a lot of and propolis, the similar effect of Margarita, but compares slightly inferior with two monarchs drug of distinguishing the flavor of.
Ganoderma spore powder: its immunoregulation effect and antitumor efficacy are for catching people's attention.
Cordyceps: warm in nature, sweet in the mouth is returned kidney, lung meridian.Effect: lung benefiting tonifying the lung, hemostasis and phlegm; Merit is specially mended gate of vitality's kidney tonifying sun, and sexual impotence, seminal emission, the kidney essense that causes for insufficiency of kidney-YANG declines and reach soreness of waist and knee joint less special efficacy is arranged.Recent studies, Cordyceps have good immunologic function regulating action, and be useful to the heart, liver function.
More than 4 flavors admit defeat altogether with the hall and be ministerial drug, make two flavor monarchs drug further strengthened.
Radix Ginseng: warm in nature, sweet in the mouth, little hardship.Return spleen, lung meridian.Effect: strongly invigorating primordial QI, has to draw and takes off the distinguished service of rescuing danger He Yingwei, beneficial mind.The present invention general with the same usefulness of stilbene art, be mainly used in enriching spleen-QI, tonifying the lung gas.
The Radix Astragali: warm in nature, sweet in the mouth is returned spleen, lung meridian.Effect: tonifying Qi and lifting yang, benefit are defended with table, diuretic detumescent.
The Rhizoma Atractylodis Macrocephalae: warm in nature, bitter in the mouth, sweet.Return spleen, stomach warp.Effect: air making-up and spleen enlivening, the dampness diuretic, hidroschesis is antiabortive.
Poria: property is flat, sweet in the mouth, light.GUIXIN, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating, calm the nerves.
Rhizoma Dioscoreae: property is flat, sweet in the mouth.Return spleen, lung, kidney channel.Effect: supplementing QI and nourishing YIN, spleen reinforcing, lung, kidney.
The Radix Paeoniae Alba: cold nature, bitter in the mouth, acid.Return liver, spleen channel.Effect: the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG.
Radix Angelicae Sinensis: warm in nature, sweet in the mouth, suffering.Return liver, the heart, spleen channel.Effect: enrich blood, invigorate blood circulation, pain relieving, intestine moistening.
Rhizoma Zingiberis: hot in nature, acrid in the mouth.Return spleen, stomach, the heart, lung meridian.Effect: warming middle-JIAO, recuperating depleted YANG.Warming the lung to resolve fluid-retention.
Cortex Cinnamomi: hot in nature, acrid in the mouth, sweet.Return kidney, spleen, conscience warp.Effect: it is supporing yang to mend fire, dispersing cold for relieving pain, warming the meridian and promoting blood circulation.The present invention mainly gets the effect of its kidney warming sun.
Semen Cuscutae: property is flat, sweet in the mouth, suffering.Return the liver,kidney,spleen warp.Effect: the YANG invigorating tonifying YIN, the controlling nocturnal emission with astringent drugs reducing urination, antidiarrheal makes eye bright.The present invention mainly gets the effect of its kidney-replenishing.
XUANJU: kidney tonifying sun, expelling wind and removing dampness.Modern study has the effect of two-ways regulation immunologic function.
Fructus Ligustri Lucidi: cool in nature, sweet in the mouth, hardship are returned liver, kidney channel.Effect: the moon of liver and kidney tonifying, clearing away heat to improve acuity of vision, black hair.The present invention general with the same usefulness of black sweat lotus compatibility, mainly get the moon of its nourishing the liver and kidney.
Black sweat lotus: cold in nature, sweet in the mouth, acid.Return liver, kidney channel.Effect: cooling blood for hemostasis, the moon of nourishing the liver and kidney.
The Rhizoma Anemarrhenae: cold in nature, bitter in the mouth, sweet.Return lung, stomach, kidney channel.Effect: clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.The present invention mainly gets its effect of rushing down the pathogenic fire of part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels unrooted.
Cortex Phellodendri: cold in nature, bitter in the mouth.Return kidney, bladder, large intestine channel.Effect: heat clearing and damp drying, eliminating fire and detoxication, YIN nourishing reducing the asthenic fever.The present invention mainly gets the damp and hot effect that its clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels has type.Know that Bai Tongyong must increase the effect of its nourishing kidney, hard kidney, heat clearing away, pathogenic fire reducing.
Rhizoma Coptidis: cold in nature, bitter in the mouth rushes down damp and hot in the heart-fire of having a surplus, the bowel relieving, and kind regulating the function of middle-JIAO is its chief to separate pyretic toxicity.The present invention mainly gets the effect of the burnt damp and hot and tool eliminating fire and detoxication of its kind a good appetite suddenly appearing in a serious disease, is used to improve the long-term chronic diarrhea of HIV sufferers.
Fructus Gardeniae: cold in nature, bitter in the mouth, GUIXIN, lung, flavor, tri-jiao channel.Effect: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.The present invention mainly gets it and kind rush down the pathogenic fire of upper, middle and lower three warmers and cardiopulmonary stomach and remove vexed effect.
Radix Trichosanthis: cold in nature, bitter in the mouth, little sweet.Attach to the lung and stomach meridians.Effect: clearing away heat and promoting production of body fluid, detumescence and apocenosis.
Radix Paeoniae Rubra: cold nature, bitter in the mouth.Return Liver Channel.Effect: clearing away heat and cooling blood, stasis-dispelling and pain-killing.
Radix Scrophulariae: cold in nature, bitter in the mouth, sweet, salty.Return lung stomach, kidney channel.Effect: heat-clearing and toxic substances removing, yin nourishing softening the hard mass.The collaborative utilization of last three flavors is used to alleviate the discomfort of the various complication of acquired immune deficiency syndrome (AIDS).
Radix Bupleuri: cold nature, bitter in the mouth, suffering.GUIXIN envelope, liver, gallbladder, tri-jiao channel.Effect: soothing liver-QI for relieving depression, reducing fever by reconciliation, elevate a turnable ladder yang-energy.The present invention general with Radix Curcumae, the Radix Linderae with the effect of mainly getting its soothing liver-QI for relieving depression, circulation of qi promoting intestinal stasis relieving.
Radix Curcumae: cold in nature, acrid in the mouth, hardship.GUIXIN, liver, gallbladder meridian.Effect: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, removing heat from blood clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.
The Radix Linderae: warm in nature, acrid in the mouth.Return lung, spleen, kidney, urinary bladder channel.Effect: promoting the circulation of QI to relieve pain, warming kidney for dispelling cold.
Modern study proves that stagnation of liver-QI, the stagnation of QI, high pressure, high anxiety, height stress not only can increase blood viscosity, make hypertension, cause blood stasis, and can reduce the human body self immunologic function rapidly, significantly.More than two flavors, 5 usefulness, be intended to alleviate the indication symptom of eliminating HIV sufferers.
Radix Et Rhizoma Rhei: cold in nature, bitter in the mouth.Return spleen, stomach, large intestine, liver, heart channel.Effect: heat and toxic materials clearing away, clearing away heat-fire, detoxifcation, blood circulation promoting and blood stasis dispelling.
Semen Coicis: cold nature, slightly sweet flavor.Return spleen, stomach, lung meridian.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating, eliminating impediment, clearing away heat and discharging pus.
Herba Artemisiae Scopariae: cold nature, bitter in the mouth.Return spleen, stomach, liver, gallbladder meridian.The effect eliminating damp-heat, jaundice eliminating.
Bi : property is flat, bitter in the mouth.Return liver, stomach, urinary bladder channel.Effect: divide Qinghua turbid, diuresis is dried, and the special stranguria weight in wet base of merit is apt to separate part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels herpes simplex poison in hot person.
Herba Euphorbiae Helioscopiae: facts have proved that this product and last three flavors, 5 usefulness have highly effective toxin expelling effect, can just get rid of HIV (human immunodeficiency virus) external rapidly by two.
Glucose is misery: zinc is relevant with the activity of 200 plurality of enzymes, plays an important role in the metabolism of tissue, breathing, protein, fat, carbohydrate, nucleic acid; Be the activator of enzyme in the insulin, protection skin arranged, safeguard immunologic function that the effect of the normal development that promotes tissue repair and sexual organ is arranged; Zinc still is the main active of SOD, and SOD then is the key factor of free radical resisting, and therefore, zinc has anticancer and antidotal important function again.Phenomenons such as appetite attenuating, amblygeustia, anemia, hepatosplenomegaly, pachylosis, mental retardation, dysplasia may appear in zinc deficiency.Child's zinc deficiency can make growth retardation and influence intelligence development.
Succinic acid germanium: be immunostimulant.
The DL methionine: human body one of must aminoacid, has the effect of the liver function of reinforcement, more can strengthen the detoxicating functions of liver with the vitamin B6 compatibility.The present invention mainly gets its powerful detoxicating functions, suppresses HIV regeneration.
Orotic acid: have detoxicating functions.The present invention gets the effect of its collaborative detoxifcation.
Thioctamide: have the liver protecting, increase animal starch quantity in the liver, powerful detoxicating functions is surprising.The present invention gets it and impels HIV to excrete fast, impels leukocyte, lymph corpuscle to recover the effect of immunologic function rapidly.
Vitamin C: have the ascorbic acid effect.Effective in cure to vitamin C deficiency, gingivitis, hemorrhage, have anti-radical action.
Above Chinese and western drugs hybrid combination makes up for each other's deficiencies and learn from each other, positive so-called blending the east and the west, bring out the best in each other.And selected Western medicine all follows and can attack to cause of disease, simultaneously the human body self immunologic function had protection and facilitation again, and this criterion certainly has no side effect.
Facts have proved that spleen is the huge organ of human immunity, lung, kidney, liver are also all playing the part of crucial role in the immunologic function huge system.The present invention is by the synergism of Chinese and western drugs, and focusing on by across-the-board regulation, balance is the vital organs of the human body function of center of gravity with spleen, lung, kidney, liver, and then realizes comprehensive, the comprehensive improvement of human body self immunologic function; And when being conceived to effect a permanent cure, strengthen the dynamics of taking stopgap measures from every side, thereby can alleviate the various symptoms of acquired immune deficiency syndrome (AIDS) rapidly, can reach the radical cure effect again.
The principles of formulating prescriptions of the present invention are: directly virus killing (attacking to cause of disease) and virus killing indirectly (reach suppress kill virus by enhance immunity) is based on indirectly; Virus killing and toxin expelling are based on toxin expelling; Endexoteric, with interior because main.
The design process of technical scheme of the present invention at first is the process of innovation for the acquired immune deficiency syndrome (AIDS) theoretic knowledge, is then to carry out " reason, method, side, medicine " Procedure of Innovation comprehensively according to innovation theory.
Nearly all medical science worker who is engaged in acquired immune deficiency syndrome (AIDS) research is seeking the medicine that can more effectively suppress and kill HIV (human immunodeficiency virus) to full capacity; A lot of modern medicine scientists also very pay close attention to Chinese medicine and pharmacy, yet the focus that they pay close attention to but is: " how to filter out effective inhibition and kill the kind of HIV (human immunodeficiency virus) from ten hundreds of herbal species." should be pointed out that this is the mistaken ideas in the acquired immune deficiency syndrome (AIDS) research.Can walk out these mistaken ideas, be related to the mankind and can finally defeat acquired immune deficiency syndrome (AIDS).
We think that human body does not still possess the specific immune ability for HIV when infected by HIV (HIV (human immunodeficiency virus)), and still unable the resisting of human body self immunologic function removed HIV, and this is the inside basic reason of human body generation acquired immune deficiency syndrome (AIDS), is primary reason.HIV (human immunodeficiency virus) is invaded human body, then is the external cause that makes human body generation acquired immune deficiency syndrome (AIDS), is deputy reason.External causes are the conditions for change, and endogenous cause of ill is only the basis of variation.HIV can only become condition human and primate generation acquired immune deficiency syndrome (AIDS), but can not become the condition that acquired immune deficiency syndrome (AIDS) take place other animals, does not more go HIV can become the condition that makes stone generation acquired immune deficiency syndrome (AIDS), because their basis of endogenous cause of ill has nothing in common with each other.
Therefore, attacking HIV (virulence factor, it is perhaps more definite to be referred to as outside virulence factor) time, should adjust, recover, strengthen, rebuild the human body self immunologic function to full capacity, and help human body with the struggle of HIV in realize foundation for the specific immune function of HIV; The human body self immunologic function is to defeat the main body fresh combatants of HIV (human immunodeficiency virus) all the time, and medicine chemotherapy, physiotherapy or the like treatment means then is the foreign aid army that helps the human body Fighting Disease.
Therefore, the human struggle of carrying out with acquired immune deficiency syndrome (AIDS) should be placed above the other things adjusting, recover, strengthen, rebuild the human body self immunologic function all the time; And the objective factor of attacking this reverse acquired immune deficiency syndrome (AIDS) of virulence factor is important howsoever, compares with subjective factors, all must be placed on relative less important, on obey second; This should be instruct to establish radical cure acquired immune deficiency syndrome (AIDS) prescription (be not only drug prescription, also comprise the prescription of therapy such as physics) the mandatory Supreme Judicial Court of institute then (or method of treatment general provisions).
From the above-mentioned Supreme Judicial Court then, any effective Therapeutic Method, with when attacking virulence factor, can protect and strengthen human body self the immunity energy, for the spontaneous recovery energy of disease, for the self-regeneration of damaged tissues can therapy be preferred therapy; With when attacking virulence factor, do not damage human body self immunity energy, spontaneous recovery energy, self-regeneration can therapy be available therapy; Immunity energy with severe impairment human body when attacking virulence factor, the spontaneous recovery energy, the therapy of self-regeneration energy is best no therapy, because such therapy is failed to differentiate between the enemy and ourselves, even act as cat's paw for an evil-doer, although such therapy is strong for the attack of virulence factor, even if but for the treatment of diseases resemble the pulmonary tuberculosis all need at least half a year at most the long-term treatment of one or two years could cure, and for resembling cancer, from disorders of blood, the super pertinacious disease of acquired immune deficiency syndrome (AIDS) and so on, then thoroughly the probability of cure diseases is minimum, can only be that the huge cost of cost exchanges of short duration life prolongation for; The best no therapy that " HAART " comes to this.
Based on above-mentioned " reason, method ", when group " side " usefulness " medicine " monarch ＂, minister, help, make the selection of ＂, all strict with endogenous cause of ill first, exopathogenic factor the second, interior because main, outer because the endogenous cause of ill main body of assisting is treated rule.From the disclosed patent documentation that can retrieve, can see, as the present invention with propolis, Margarita, etc. 2 flavor Chinese medicines be monarch drug; With Lac regis apis, Pollen Pini, Ganoderma spore powder, Cordyceps, etc. 4 flavor Chinese medicines be ministerial drug; With twenties flavor Chinese medicines such as the Radix Astragali, Herba Euphorbiae Helioscopiae, BIXUAN is adjuvant; The prescription design that comprehensive body autoimmune function is carried throughout is peerless.
Dialectical materialism is thought: the essence of vital movement is the particular form that material exists.Medical research proves, the various forms of body normal physiological state or pathological state are closely related with the variation of the quantity of the material element that constitutes human body or quality invariably.Adopting the Drug therapy disease, is nothing but the content of artificially adjusting material elements such as intravital macroelement of people and trace element, a kind of means of ratio.Recognize this point, and its process of profound understanding, for instructing us, have crucial meaning how according to " reason, method " group " side " usefulness " medicine "; " it " can tell we pass through to replenish which contained element of which medicine, go to correct the biased of vital movement desired material element, make it to reach best gold proportioning, the balance of the people's homeostasis in the time of just can rebuliding the normal physiological state destroyed.The balance of people's homeostasis is the balance of material element quality and quantity in the human body after all, the balance between beneficial element and the harmful element; Virulence factor is the harmful substance element that trespasses human body.These also are to instruct our rule in prescription design and selection medication.
Motherland's medical science emphasizes that " strengthening vital QI to eliminate pathogenic factors " think that " in healthy energy deposited, heresy can not be done." " institute of heresy gathers, and its gas must be empty." " just " and " healthy energy " that refer to here be normal, complete human body self immunologic function; Here " heresy " that refers to is " virulence factor ", " paathogenic factor " and for the pathological lesion of human body." setting upright ", is exactly by adjusting the proportioning of various material elements in the human body, helping human body to strengthen the ability of defeating virulence factor, resisting paathogenic factor, repair pathological lesion.Medical science and medical worker's task is: by setting upright the purpose that reaches eliminating evil, by adjusting, recover, strengthen, rebuild the autoimmune function of human body, reach virulence factor is driven away outside the human body totally, thoroughly, fully, and repair because the purpose of the pathological lesion that virulence factor caused; And be not only that direct replacement human body self immunologic function removes to kill the inhibition virulence factor.
The prescription that adopts the technical solution of the present invention compatibility to form, start with from the logical vital organs of the human body, the qi-blood-body fluid of transferring, go to realize eliminating HIV (human immunodeficiency virus) or it being evicted from external by comprehensive body autoimmune function, and repair, and then reach the purpose of radical cure acquired immune deficiency syndrome (AIDS) because HIV (human immunodeficiency virus) infection is given human body, organized the pathological lesion that causes.Acquired immune deficiency syndrome (AIDS) is once healing, and the specific immune ability for HIV (human immunodeficiency virus) has been given birth in the human body sell of one's property, thereby infects HIV (human immunodeficiency virus) later on again, also acquired immune deficiency syndrome (AIDS) can not take place again.
The present invention is not only fruitful for the treatment of acquired immune deficiency syndrome (AIDS), and through the suitable plus-minus to prescription, is applicable to any treatment of diseases relevant with autoimmune function.Because designed prescription has dual regulation for the human body self immunologic function.Not only can make immunodeficiency be restored, repair, strengthen and set up specific immune function, and can make the autoimmune disease that often needs to adopt immunosuppressant to treat obtain same fruitful treatment for HIV (human immunodeficiency virus) resemble the acquired immune deficiency syndrome (AIDS).The ＂ immunostimulant ＂ of modern medicine and ＂ immunosuppressant ＂ are the products of formal logic thinking mode, and the ＂ dual regulation ＂ of ＂ modern Chinese medicine ＂ then is the product of the mode of thinking of dialectical logic.
In sum, the present invention studies exploration with the mode of thinking of dialectical logic to acquired immune deficiency syndrome (AIDS), the traditional Chinese medical science immunology principle that proposes according to the inventor and for the original understanding of the etiology and pathogenesis of acquired immune deficiency syndrome (AIDS), the result who carries out technological innovation from Chinese medicine and pharmacy reason, method, side, four aspects of medicine.The present invention starts with from the logical vital organs of the human body, the qi-blood-body fluid of transferring, go to realize eliminating HIV (human immunodeficiency virus) or from the external purpose of evicting by the body autoimmune function, process is to 21 routine AIDS1 type patient preliminary identifications, and HIV (human immunodeficiency virus) is changeed because of rate 100%, and does not rebound after the drug withdrawal.Popularize along with of the present invention, the mankind will finally defeat acquired immune deficiency syndrome (AIDS).
The specific embodiment:
Implement 1:
Below be the best proportioning of 30 days consumptions of a people:
The A component: propolis 50 grams, aqueous fusion property Margarita powder 30 grams, Lac regis apis 30 grams, Pollen Pini (New Time Co.'s product) 30 grams, Ganoderma spore powder 20 grams, Cordyceps 30 grams.(with propolis with the medical ethanol of 95% concentration of 5 times of amounts soak melt standby; The Cordyceps levigation is standby.)
The B component:
Radix Ginseng 30 grams, the Radix Astragali 30 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Poria 30 grams, Rhizoma Dioscoreae 30 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Cortex Cinnamomi 30 grams, Rhizoma Zingiberis 30 grams, Semen Cuscutae 30 grams, XUANJU 30, Fructus Ligustri Lucidi 30 grams, Herba Ecliptae 30 grams, the Rhizoma Anemarrhenae 30 grams, Cortex Phellodendri 30 grams, Rhizoma Coptidis 20 grams, Fructus Gardeniae 30 grams, Radix Trichosanthis 30 grams, Radix Paeoniae Rubra 30 grams, Radix Scrophulariae 30 grams, Radix Bupleuri 30 grams, Radix Curcumae 30 grams, the Radix Linderae 30 grams, Radix Et Rhizoma Rhei 20 grams, Semen Coicis 30 grams, Artemisia anethoicles Mattf 30 grams, Bi 30 grams, Herba Euphorbiae Helioscopiae 20 grams.(it is powdered that the B component extracts concentrate drying by prior art, and Weight control is about 3-5% of crude drug).
C component: misery 30 grams of glucose, succinic acid germanium 6 grams, DL methionine 20 grams, orotic acid 2 grams, thioctamide 0.8 gram, vitamin C 3 grams, silymarin 0.8 gram.(the C component is powdery or is processed into powdery standby)
With the propolis alcoholic solution is excipient, with above-mentioned A, B, C component mixing, detects qualified back and is pressed into tablet with tablet machine, makes the coated tablet packing then.
Embodiment 2:
By prior art processes the prescription of embodiment 1 is made oral liquid.
Above embodiment is not as a limitation of the invention.Also can be made into ball that medically acceptable, galenic pharmacy can realize, loose, any dosage forms such as cream, pellet, injection.These all are for well known to a person skilled in the art prior art, need not giving unnecessary details at this.
Claims (1)
1, a kind of pharmaceutical composition that effects a radical cure acquired immune deficiency syndrome (AIDS) is characterized in that, the technical program is formed by following Chinese and western drugs compatibility:
Monarch drug: propolis 5%, aqueous fusion property Margarita powder 3%.
Ministerial drug: Lac regis apis 3%, Pollen Pini 3%, Cordyceps 3%, Ganoderma spore powder 2%.
Adjuvant: Radix Ginseng 3%, the Radix Astragali 3%, the Rhizoma Atractylodis Macrocephalae 3%, Poria 3%, medicine 3%, the Radix Paeoniae Alba 3%, Radix Angelicae Sinensis 3%, XUANJU 3%, meat Du 3%, Rhizoma Zingiberis 3%, Semen Cuscutae 3%, Fructus Ligustri Lucidi 3%, Herba Ecliptae 3%, the Rhizoma Anemarrhenae 3%, Cortex Phellodendri 3%, Rhizoma Coptidis 2%, Fructus Gardeniae 3%, Radix Trichosanthis 3%, Radix Paeoniae Rubra 3%, Radix Scrophulariae 3%, Radix Bupleuri 3%, Radix Curcumae 3%, the Radix Linderae 3%, Radix Et Rhizoma Rhei 2%, Semen Coicis 3%, Herba Artemisiae Scopariae 3%, Bi 3%, Herba Euphorbiae Helioscopiae 2%.
In above-mentioned Chinese medicine preparation, add the Western medicine of following kind and quantity in per 30 days consumptions:
Misery 90 grams of glucose, succinic acid germanium 18 grams, DL methionine 60 grams, orotic acid 6 grams, thioctamide 2.4 grams, vitamin C 9 grams, silymarin 0.8 gram.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 02130603 CN1413727A (en) | 2002-09-09 | 2002-09-09 | Composite medicine for radical curing AIDS |
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| CN 02130603 CN1413727A (en) | 2002-09-09 | 2002-09-09 | Composite medicine for radical curing AIDS |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007065314A1 (en) * | 2005-12-08 | 2007-06-14 | Pficker Pharmaceuticals, Ltd. | Compound preparation for treating virus hepatopathy |
| CN102302510A (en) * | 2010-06-24 | 2012-01-04 | 攀枝花兴辰钒钛有限公司 | Medicinal composition and application thereof |
| EP2857031A4 (en) * | 2012-05-29 | 2015-11-25 | Jiangzhong Pharmaceutical Co Ltd | Composition for preventing and treating aids and preparation method thereof |
| JP2021161045A (en) * | 2020-03-31 | 2021-10-11 | 株式会社古川リサーチオフィス | Zinc compound mixed composition |
-
2002
- 2002-09-09 CN CN 02130603 patent/CN1413727A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007065314A1 (en) * | 2005-12-08 | 2007-06-14 | Pficker Pharmaceuticals, Ltd. | Compound preparation for treating virus hepatopathy |
| CN102302510A (en) * | 2010-06-24 | 2012-01-04 | 攀枝花兴辰钒钛有限公司 | Medicinal composition and application thereof |
| CN102302510B (en) * | 2010-06-24 | 2014-04-23 | 攀枝花兴辰钒钛有限公司 | Medicinal composition and application thereof |
| EP2857031A4 (en) * | 2012-05-29 | 2015-11-25 | Jiangzhong Pharmaceutical Co Ltd | Composition for preventing and treating aids and preparation method thereof |
| US9861671B2 (en) | 2012-05-29 | 2018-01-09 | Jiangzhou Pharmaceuticals Co., Ltd. | Composition for preventing and treating aids and preparation method thereof |
| JP2021161045A (en) * | 2020-03-31 | 2021-10-11 | 株式会社古川リサーチオフィス | Zinc compound mixed composition |
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