CN102755346A - Compound polysaccharide formula of edible fungus as well as preparation method and application thereof - Google Patents
Compound polysaccharide formula of edible fungus as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to a compound polysaccharide formula of edible fungus as well as a preparation method and an application thereof. The compound polysaccharide formula comprises the following materials in parts by weight: 50-150 parts of phellinus linteus polysaccharides, 50-150 parts of grifolan and 50-150 parts of hericium erinaceus polysaccharide. The invention is conductive to enhancing the immunologic function of a human body, is anti-tumor, has the action for relieving and treating the diseases such as tumor patients, low resistance, arteriosclerosis, diabetes mellitus and the like and has an obvious effect for calming the nerves of crowds with high mental level and neurasthenia.
Description
Technical field
The present invention relates to a kind of edible mycotic composite amylase prescription, method for preparing and application thereof.
Background technology
Complex polysaccharide is by the Chinese medicine ultimate principle, with the cooperation rule of " monarch, the minister, help, make " of prescriptions of Chinese medicine, uses high-tech means; Strict qualitative control; The fungus polysaccharide of from natural Mycophytas such as Phellinus igniarius (L. ex Fr.) Quel., Grifola frondosa and Hericium erinaceus (Bull. Ex Fr.) Pers., extracting through experiment repeatedly many times, filters out science, the most effectively the polysaccharide combination is combined with each other with ratio; Form complex polysaccharide, had stronger biological activity.Its biological activity is that any active polysaccharide is incomparable.
Complex polysaccharide has many-sided biological activity, is high-quality and best immunomodulator without any side effects in the world today, at home and abroad occupies first place.Complex polysaccharide can promote body immunity effectively comprehensively, is again the pith of cell and organelle structure, is that human body cell or internal organs maintain the indispensable Main Ingredients and Appearance of normal function.Clinical proof, complex polysaccharide is compared with the single-activity polysaccharide, no matter on the amplitude of immune activation, still on the aspect of immune activation, all substantially exceeds the effect of single-activity polysaccharide.
Summary of the invention
The object of the present invention is to provide a kind of edible mycotic composite amylase prescription, method for preparing and application thereof.
The present invention is processed by following materials based on weight: comprise the raw material of following ratio of weight and number, phellin polysaccharides 50-150 part, grifolan 50-150 part, Hericium Erinaceus Polysaccharide 50-150 part.
More than the optimum weight proportioning of each composition be:
100 parts of phellin polysaccharides, 100 parts of grifolan, 100 parts of Hericium Erinaceus Polysaccharide.
The present invention has following advantage: help the enhances human body immunologic function, antitumor; To tumor patient, disease such as lower for the resistance, arteriosclerosis, diabetes has relief of symptoms and therapeutical effect.The effect of calming the nerves to mental crowd of height and neurasthenia crowd is remarkable.Raw material of the present invention all selects for use the high-quality fungus sporophore through the technology fermented extracted.Directly the fill gained does not add food additive such as any artificial flavors, artificial color, and pure natural is pollution-free.
It is rigorous rationally to occur the edible fungi polysaccharide scientific formulation in the preparation of the present invention, composition, clear efficacy.
Feedstock analysis:
Phellinus igniarius (L. ex Fr.) Quel. is the sporophore of Polyporaceae fungus phellinus igniarius Phellinus igniarius (L.ex Fr.) Qu é l..Have another name called: parasitic on Sang Chen, Phellinus igniarius (L. ex Fr.) Quel. mushroom, the Mulberry.
[nature and flavor] mildly bitter flavor, cold in nature.Return liver, kidney channel.
The sharp the five internal organs of [effect] ability, softening the hard mass, toxin expelling, stomach function regulating antidiarrheal is invigorated blood circulation in hemostasis.Cure mainly gonorrhea, bleeding not during menses, lump in the abdomen, addiction drink, diarrhea due to hypofunction of the spleen.
Compendium of Material Medica: " sharp the five internal organs, a surname's flatus, toxin expelling gas ".
[nutritional labeling]
Modern study confirms: contain agaric acid, veratric acid ,-4,5 dimethoxy-1,2-phthalic acid; Ergosterol, the satisfied fatty acid of C22, C24, C26, the saturated hydrocarbons of C23, C25, glycine; Aminoacid such as aspartic acid, oxalic acid, manna fucogalactan, xylose oxidase; And catalase, urase, esterase, polysaccharide etc.The same with clinical medicinal fungis such as other ganoderan, lentinan, pachymans, its main active is a polysaccharose substance.
[pharmacological action of phellin polysaccharides]
1, antitumaous effect is mainly realized in the following manner:
(1) reinforced immunological power, inducing cancer cell are dead voluntarily;
(2) propagation of anticancer and transfer;
(3) alleviate the side effect of chemotherapy and radiation;
(4) alleviate the distinctive pain of cancer patient;
(5) stop ulcer, polyp, benign tumor etc. to cancerate and be cancer;
(6) prevent, avoid the recurrence of cancer.
2, liver protection effect anti-hepatic fibrosis promotes liver cell regeneration, can be used for preventing and treating chronic hepatitis, liver cirrhosis, hepatic ascites etc.
3, reduce and the adjustment blood sugar concentration, effectively prevent and improve diabetes.
4, blood fat reducing prevents arteriosclerosis, prevents the generation of cardiovascular and cerebrovascular disease.
5, prevention and treatment rheumatoid arthritis.
6, phellinus linteus extract can suppress uric acid fully, and gout is had good result.
7, antiallergic, fine to allergic rhinitis, cureless eczema curative effect.
Relevant research shows that Phellinus igniarius (L. ex Fr.) Quel. and extract are harmless to human non-toxic, even long-term large dose oral administration is also without any side effects.
Grifola frondosa is the sporophore of Polyporaceae fungus hen of the woods Polyporus frondosus (Dicks.) Fr., also claims hen of the woods, dance young pilose antler, thousand Buddhist bacterium, Semen Castaneae mushroom, is a kind of mushroom that grows thickly that is grown under the Chinese chestnut tree.
[nature and flavor] sweet in the mouth, property is flat.
[effect] replenishing QI to invigorate the spleen; Tonify deficiency is set upright.Main deficiency of the spleen causing weakness of QI; Fatigue and asthenia; Spiritlessness and sparing of words; Diet reduces; Abdominal distention after meal; The person that has the above-mentioned symptom after tumor patient radiotherapy or the chemotherapy.
[nutritional labeling]
Modern study confirms: Grifola Frondosa sporophore not only contains protein, cellulose, unsaturated fatty acid, vitamin B
1, vitamin C, also contain a large amount of active substance polysaccharide; Protein and amino acid content are 2 times of Lentinus Edodes.
[pharmacological action of grifolan]
1, antitumor action
Grifolan mainly is a beta glucan.Numerous species wherein all has very strong anti-tumor activity.
Grifolan can the active cell immunologic function, improve body non-specific with the specific immunity ability, the chemotherapy or the radiotherapy of collaborative tumor, the effect of performance immunochemotherapy or immunoradio-therapy reaches the purpose of treatment tumor.
2, immunoregulation effect
Pharmacological such as grifolan antitumor, antiviral all with its activating immune system, to regulate immunologic function relevant.The effect that grifolan improves immunity is many-sided, not only can improve the nonspecific immunity of body, and can improve the specific immune function of body, and it can activate natural killer cell (NK), T cell, promotes macrophage phagocytic active.
3, antivirus action
The grifolan oral medicine has the better protect effect for the infection that influenza virus and I herpes simplex virus type (representing RNA viruses and DNA viruses respectively) cause, this effect has tangible dose-effect relationship.Double to take not only sx, and can not cause fever.This possibly be that grifolan has the effect that promotes virus induction interferon and human body immunity improving power and bring into play.
4, treatment hepatitis effect
No matter oral grifolan still injection all have significant treating hepatitis effect, can significantly reduce the hepatic injury that oral paracetamol causes and the rising of glutamic oxaloacetic transaminase, GOT concentration in glutamate pyruvate transaminase and the blood in the blood that causes.Grifolan can relieve the effect of alcohol, thereby plays liver-protective effect.
5, to the influence of endocrine and cardiovascular system
Grifola frondosa and polysaccharide have the effect of blood sugar regulation, and it can directly combine with Insulin receptor INSR, increase the sensitivity of insulin, effectively improve the corresponding symptom of diabetes.
Grifola frondosa has tangible blood fat reducing and increases lipometabolic effect.
Hericium erinaceus (Bull. Ex Fr.) Pers. is the sporophore of the monkey mushroom bacterium Hericium erinaceus of Aphyllophorales hedgehog fungus section (Bull.ex Fr.) Pers..
[nature and flavor] sweet in the mouth, property is flat.Return spleen, stomach warp.
[effect] sharp the five internal organs, aid digestion, invigorating the spleen and replenishing QI, calm the nerves, antiinflammatory.
"Seaboard Geographic foreign body": "Min Jie hedgehog soup taste good, although five of meat and meat broth can not, its vulgar Yanyue: Negative Chin Su Ning, unwilling to bear hedgehog soup.”
[nutritional labeling]
Modern study confirms: every hectogram (dry weight) Hericium erinaceus contains protein 26.3 grams, fat 4.2 grams, carbohydrate 44.9 grams, fine fibre 6.4 grams, moisture content 10.2 grams, 850 milligrams in phosphorus, 18 milligrams of ferrum, 2 milligrams of calcium, vitamin B
10.89 milligram, vitamin B
21.89 milligram, 0.01 milligram of carotene, 323 kilocalories of heats.6 kinds of amino acid/11s are arranged, 7 kinds of essential amino acids are wherein arranged.
[pharmacological action of Hericium Erinaceus Polysaccharide]
1, antiulcer and antiinflammatory action.
2, antitumor action.
3, liver protection function.
4, increase immunity, anti-aging effects.
5, improve body's hypoxia tolerance, increase the heart blood output, quicken the body blood circulation.
6, the effect of blood sugar lowering and blood fat.
The specific embodiment
The preparation of embodiment 1 compound polysaccharide capsule
Prescription:
Method for making: take by weighing phellin polysaccharides, grifolan, Hericium Erinaceus Polysaccharide by weight respectively, mix homogeneously, No. 0 capsule of packing promptly gets.
The various symptoms that embodiment 2 products treatment sub-health state and neurasthenia cause
[clinical data]
Diagnose 20 clear and definite routine hypoimmunity patients: male 15 examples, women 5 examples, 35 years old mean age, city working clan, life anxiety.Take above-mentioned complex polysaccharide preparation, observe the curative effect.
[Therapeutic Method]
Diet is still taken these article twice every day, each 1.Took continuously 90 days.
[therapeutic outcome]
1, criterion of therapeutical effect:
Recovery from illness: clinical symptoms all disappears, and it is normal that body function recovers.
Produce effects: therapeutic effect is obvious, and clinical symptoms disappears basically.
Effectively: compare with the symptom before these article of taking, have clear improvement, alleviated the degree of some clinical symptoms.
Invalid: no change before and after the treatment.
2, patient's feedback: 17 examples of fully recovering account for 85%; 2 examples that take a turn for the better account for 10%; Effective 1 example accounts for 5%; Invalid 0 example accounts for 0%.The present invention is 85% helping the total cure rate aspect the enhancing immunity.
Toxic and side effects: show in the feedback information according to the patient that untoward reaction appears in no patient.
[model case]
Patient Zhang, the woman, 35 years old, be engaged in high intellectual work, to work every day 15 hours, life is nervous.Long-term serious insomnia, daytime lassitude, nervousness etc.And it is in disorder like indigestion and loss of appetite, distension and fullness in the abdomen, feel sick belch, sensation of oppression over the chest with shortness of breath, cardio palmus shape with internal organs.Health check-up can not check again and the corresponding positive sign of symptom.
Curative effect: after taking for two weeks, find that stomach has not expanded, appetite strengthens, and the mental status takes a turn for the better.So continued to take three months.Patient's readme has not had above symptom fully.
Side effect such as embodiment 3 products treatment tumor patient is weak because of the health that chemotherapy causes, gastricism
[clinical data]
Clarifying a diagnosis is patient's 20 examples of tumor, liver cancer patient 14 examples (operation back convalescence), and patients with lung cancer 6 examples (during the chemicotherapy) are taken above-mentioned complex polysaccharide preparation, observe the curative effect.
[Therapeutic Method]
Diet is still taken these article twice every day, each 1.Took continuously 90 days.
[therapeutic outcome]
1, criterion of therapeutical effect:
Recovery from illness: clinical symptoms all disappears, and it is normal that body function recovers.
Produce effects: therapeutic effect is obvious, and clinical symptoms disappears basically.
Effectively: compare with the symptom before these article of taking, have clear improvement, alleviated the degree of some clinical symptoms.
Invalid: no change before and after the treatment.
2, patient's feedback: in liver cancer patient 14 examples, 0 example of fully recovering, produce effects 8 examples, effective 4 examples, invalid 2 examples; Total effective rate: 85.7%; In patients with lung cancer 6 examples, 0 example of fully recovering, produce effects 4 examples, effective 1 example, invalid 1 example; Total effective rate: 83.3%.
Toxic and side effects: show in the feedback information according to the patient that untoward reaction appears in no patient.
[model case]
Patient Lee, man, 60 years old.Be that pulmonary carcinoma is early stage after diagnosing, receive the chemicotherapy treatment after, occur that whole body fatigue and weak, lethargy, immunologic function degression, appetite descend, dietary amount reduces, feel sick, symptoms such as vomiting, abdominal distention, stomachache, diarrhoea.
Curative effect: after taking for two weeks, find that appetite strengthens, in high spirits, drowsiness sx.So continued to take three months.Patient's readme has not had above symptom basically, and quality of the life has had and increases substantially.
Claims (4)
1. an edible mycotic composite amylase prescription, method for preparing and application thereof is characterized in that used raw material and parts by weight thereof: phellin polysaccharides 50-150 part, grifolan 50-150 part, Hericium Erinaceus Polysaccharide 50-150 part.
2. according to claim 1 an edible mycotic composite amylase prescription, method for preparing and application thereof, it is characterized in that the best proportioning of used raw material and parts by weight thereof: 100 parts of phellin polysaccharides, 100 parts of grifolan, 100 parts of Hericium Erinaceus Polysaccharide.
3. a kind of edible mycotic composite amylase prescription according to claim 1 and 2, method for preparing and application thereof is characterized in that: used raw material is processed oral formulations such as granule, capsule, tablet, oral liquid by its parts by weight mix homogeneously.
4. a kind of edible mycotic composite amylase prescription according to claim 1 and 2, method for preparing and application thereof is characterized in that: be used for the side effect of enhancing immunity and reduction tumour patient chemotherapy, effectively alleviate the harm of chemicotherapy to tumour patient; Be applicable to high mental work crowd and neurastheniac simultaneously.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845369A (en) * | 2014-01-17 | 2014-06-11 | 安徽省康美来大别山生物科技有限公司 | Application of phellinus igniarius extract in preparing medicine for improving immunity |
| CN104397678A (en) * | 2014-11-28 | 2015-03-11 | 哈尔滨墨医生物技术有限公司 | Protein powder preparation and production method thereof |
| CN104489459A (en) * | 2014-12-04 | 2015-04-08 | 黄艳红 | Qianfo-milkvetch root polysaccharide and preparation process thereof |
| CN104543682A (en) * | 2015-02-06 | 2015-04-29 | 蒯晶晶 | Golden rose polysaccharide and preparation process thereof |
| CN104642874A (en) * | 2015-03-23 | 2015-05-27 | 哈尔滨工业大学 | Edible fungus composite polysaccharide radiation protection agent and preparation method thereof |
| CN105011123A (en) * | 2015-08-05 | 2015-11-04 | 南京贝杉国际贸易有限公司 | Functional food for preventing tumor and assisting in anti-tumor treatment and preparing method thereof |
| CN109758496A (en) * | 2019-03-21 | 2019-05-17 | 别晨光 | A kind of anticancer improves the Chinese medicinal healthcare tea and preparation method thereof of immunity |
| CN111228327A (en) * | 2020-03-02 | 2020-06-05 | 西安医学高等专科学校 | Composition for improving contraction force of striated muscle |
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| CN101744846A (en) * | 2009-12-25 | 2010-06-23 | 福州汉方生物技术有限公司 | Edible mycotic composite amylase nutritional agent |
| CN101828695A (en) * | 2010-04-07 | 2010-09-15 | 高章奎 | Adonis amurensis edible fungus preparation and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103845369A (en) * | 2014-01-17 | 2014-06-11 | 安徽省康美来大别山生物科技有限公司 | Application of phellinus igniarius extract in preparing medicine for improving immunity |
| CN104397678A (en) * | 2014-11-28 | 2015-03-11 | 哈尔滨墨医生物技术有限公司 | Protein powder preparation and production method thereof |
| CN104489459A (en) * | 2014-12-04 | 2015-04-08 | 黄艳红 | Qianfo-milkvetch root polysaccharide and preparation process thereof |
| CN104543682A (en) * | 2015-02-06 | 2015-04-29 | 蒯晶晶 | Golden rose polysaccharide and preparation process thereof |
| CN104642874A (en) * | 2015-03-23 | 2015-05-27 | 哈尔滨工业大学 | Edible fungus composite polysaccharide radiation protection agent and preparation method thereof |
| CN105011123A (en) * | 2015-08-05 | 2015-11-04 | 南京贝杉国际贸易有限公司 | Functional food for preventing tumor and assisting in anti-tumor treatment and preparing method thereof |
| CN109758496A (en) * | 2019-03-21 | 2019-05-17 | 别晨光 | A kind of anticancer improves the Chinese medicinal healthcare tea and preparation method thereof of immunity |
| CN111228327A (en) * | 2020-03-02 | 2020-06-05 | 西安医学高等专科学校 | Composition for improving contraction force of striated muscle |
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