CN102784163A - Edible fungi compound polysaccharides health care treatment formula and preparation method thereof - Google Patents
Edible fungi compound polysaccharides health care treatment formula and preparation method thereof Download PDFInfo
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- CN102784163A CN102784163A CN2012102737672A CN201210273767A CN102784163A CN 102784163 A CN102784163 A CN 102784163A CN 2012102737672 A CN2012102737672 A CN 2012102737672A CN 201210273767 A CN201210273767 A CN 201210273767A CN 102784163 A CN102784163 A CN 102784163A
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Abstract
The invention relates to an edible fungi compound polysaccharides health care treatment formula and a preparation method thereof. The formula comprises the following raw materials according to part by weight: 20 to 60 parts of agaricus blazei murill polysaccharide, 10 to 30 parts of shii-take polysaccharide, and 5 to 15 parts of Indian buead polysaccharide. The edible fungi compound polysaccharides health care treatment formula is helpful to enhancing the immune function of a human body, improving the hematogenesis function of human bone marrow, and resisting cancers, has the effects of tonifying the liver and the kidney, strengthening the spleen and the stomach, maintaining beauty to keep young, clearing damp and promoting diuresis, and plays the role of relieving symptoms and treating for people suffering from the diseases such as cancers, anaemia, low resistance, hyperlipemia, hypertension, arteriosclerosis, diabetes, nephritis, difficult urination, oedema, edema, abdominal pain and diarrhoea.
Description
Technical field
The present invention relates to a kind of edible fungi complex polysaccharide health care treatment prescription and preparation method thereof.
Background technology
Complex polysaccharide is by the Chinese medicine ultimate principle, with the cooperation rule of " monarch, the minister, help, make " of prescriptions of Chinese medicine, uses high-tech means; Strict qualitative control; The fungus polysaccharide of from natural Mycophytas such as Agaricus blazei Murrill, Poria and Lentinus Edodes, extracting through experiment repeatedly many times, filters out science, the most effectively the polysaccharide combination is combined with each other with ratio; Form complex polysaccharide, had stronger biological activity.Its biological activity is that any active polysaccharide is incomparable.
Complex polysaccharide has many-sided biological activity, is high-quality and best immunomodulator without any side effects in the world today, at home and abroad occupies first place.Complex polysaccharide can promote body immunity effectively comprehensively, is again the pith of cell and organelle structure, is that human body cell or internal organs maintain the indispensable Main Ingredients and Appearance of normal function.Clinical proof, complex polysaccharide is compared with the single-activity polysaccharide, no matter on the amplitude of immune activation, still on the aspect of immune activation, all substantially exceeds the effect of single-activity polysaccharide.
Summary of the invention
The object of the present invention is to provide a kind of edible fungi complex polysaccharide health care treatment prescription and preparation method thereof.
The present invention is processed by following materials based on weight: comprise the raw material of following ratio of weight and number, Agaricus Blazei Murrill polysaccharide 20-60 part, lentinan 10-30 part, pachyman 5-15 part.
More than the optimum weight proportioning of each composition be:
40 parts of Agaricus Blazei Murrill polysaccharides, 20 parts of lentinan, 10 parts of pachymans.
The present invention has following advantage: help the enhances human body immunologic function, promote the hemopoietic function of people's bone marrow, antitumor; Invigorating the liver and kidney, strengthening the spleen and stomach, looks improving and the skin nourishing, promoting diuresis to eliminate damp pathogen.To tumor patient, anemia, lower for the resistance, hyperlipidemia, hypertension, arteriosclerosis, diabetes, nephritis and dysuria, edema, edema disease such as suffer from abdominal pain, have loose bowels has relief of symptoms and therapeutical effect.Raw material of the present invention all selects for use the high-quality fungus sporophore through the technology fermented extracted.Directly the fill gained does not add food additive such as any artificial flavors, artificial color, and pure natural is pollution-free.
It is rigorous rationally to occur the edible fungi polysaccharide scientific formulation in the preparation of the present invention, composition, clear efficacy.
Feedstock analysis:
Agaricus blazei Murrill is the sporophore of Agaricus edibilis fungus Agaricus blazei Murrill Agaricus blazei Murrill, has another name called Brazilian mushroom, originates in ground such as Brazil, Peru.
[nutritional labeling]
Modern study confirms: Agaricus blazei Murrill is a kind of saccharic and profuse edible fungi of protein of containing, and contained protein and polysaccharide are 2 times of Lentinus Edodes, and its polysaccharide body burden is 5 times of Ganoderma up to 6.55g/100g.Unique β-(1-6)-D-glucose structure directly acts on, but the growth activity of fast lifting natural immunity cell, the auxiliary therapeutic effect that improves.Contain vitamin B in addition
1, B
2Sporophore also contains multiple have antitumor, cholesterol reduction, blood sugar lowering, antithrombotic isoreactivity material.
[pharmacological action of Agaricus Blazei Murrill polysaccharide]
1, ability enhances human body immunologic function: it strengthens activity of immune cells such as phagocyte, T cell, B cell and natural killer cell; Impel relevant cytokine such as the interferon of immunocyte secretion; The necrocytosis factors etc. reach the purpose that promotes immunity.
2, can promote the hemopoietic function of people's bone marrow: through improving the inhibition of chemotherapy to hemopoietic function of bone marrow; Make periphery HC, platelet and total white blood cells trend normal value; Enhancing reduces toxic and side effects to the patient's that carries out radiation and chemotherapy sensitivity and toleration.Inhibited to oncocyte simultaneously, take for a long time and can consolidate Ankang.
3, can promote the effect of chemotherapeutics cyclophosphamide, 5-Fu.
4, to disturbing leukemic cell proliferation that inhibitory action is arranged.The physiologically active polysaccharide is suitable for treating leukemia of children.
5, liver, kidney there are protective effect, can take for a long time.
6, has anticancer biological function.It attracts people's attention to the nursing role of tumor patient especially, and it presses down tumor effect and occupies first of each medicinal fungi.
Lentinus Edodes is the sporophore of Tricholomataceae fungus Lentinus Edodes Lentinula edodes (Berk.) sing.
[nutritional labeling]
Modern study confirms: main component is lentinan (content in Lentinus Edodes is about 0.87%) and seed amino acid surplus in the of 10 in the Lentinus Edodes extract, and the aminoacid and the vitamin B of 7 kinds of needed by human such as isoleucine, lysine, phenylalanine, methionine, threonine, valine wherein arranged
1, B
2, B
5And mineral and crude fibre etc.Its of paramount importance active component is a lentinan.
[pharmacological action of lentinan]
1, the anti-tumor activity of lentinan
Lentinan has antitumor action, and it does not have the toxic and side effects of chemotherapeutics.Induce behind the lentinan entering antibody and produce a kind of immunocompetent cytokine that has, under the comprehensive function of these cytokines, body immune system strengthens, and tumor cell is played defence and lethal effect.Lentinan strengthens the inductive cell toxicant of antibody dependent cellular through activating macrophage, the performance anti-tumor activity; In addition, lentinan can also make the vasodilation of tumor locus and hemorrhage, causes the tumor hemorrhagic necrosis and degenerates fully.
2, lentinan anti-infectious function
It is reported that lentinan can improve macrophage function.Lentinan all has inhibitory action to Abelson virus, 12 type adenoviruss and influenza infection, is the good medicine of the particularly chronic migration-type hepatitis of the various hepatitis of treatment.
3, the immunoregulation effect of lentinan
The immunoregulation effect of lentinan is its bioactive important foundation.Lentinan is typical t cell activation agent, promotes the generation of interleukin, can also promote the function of mononuclear phagocyte, is considered to a kind of specifc immunity reinforcing agent.Its immunization characteristics are that it can promote the generation of lymphocyte activating factor (LAF), discharge various ThFs, strengthen host's peritoneal macrophage phagocytic rate, recover or stimulate the function of helper T lymphocyte.In addition, lentinan can also generate by enhancing antibody, suppresses macrophage and discharges.
4, the antiviral activity of lentinan
Lentinus Edodes contains a kind of double stranded RNA, can stimulate human body skein cell and leukocyte to discharge interferon, and interferon has antivirus action.The absorption herpesvirus that shiitake mushroom hypha extract is capable of inhibiting cell, thus all kinds of diseases that herpes simplex virus, cytomegalovirus cause prevented and treated.
Poria is the dry sclerotia of Polyporaceae fungus Poria Poria cocos (Schw.) Wolf, is commonly called as Poria, Song Ling, Poria.
[nature and flavor] sweet in the mouth, light, property are flat, GUIXIN, lung, spleen, kidney channel.
[effect] promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.
Shennong's Herbal: " the contrary gas of the breast side of body, melancholy is angerd in terror, and the heart is the knot pain down, cold and heat stuffy sensation with restlessness cough with dyspnea, mouthful burnt dry tongue, diuresis, clothes peace soul is reposed not hungry prolonging life for a long time.”
" Japan hanako materia medica ": " mend five kinds of strain and seven kinds of impairment, antiabortive, warm waist knee joint, happy Fructus Alpiniae Oxyphyllae, only forgetful.”
[nutritional labeling]
Modern study confirms: the Poria main component is polysaccharide (wherein pachyman content reaches as high as 75%) and triterpenoid compound.In addition, contain histidine, adenine, choline, β-pachyman enzyme, protease, lauric acid, Palmic acid, fat, lecithin, ergosterol, phosphatidylcholine etc.
[pharmacological action of pachyman]
1, antitumor action
Clinical research, pachyman has certain curative effect to nasopharyngeal carcinoma, gastric cancer.Its antitumor mechanism is: pachyman activates local new body, and the new body that the tumor near zone is activated influences macrophage, lymphocyte or other cells and humoral factor, thus the Synergistic killing tumor cell.Pachyman can also activate the immunologic surveillance system to tumor.
2, immunomodulating and antivirus action
Pachyman have regulate immunity, the liver protecting and ALT lowering, indirectly antiviral, induce and short inducement interferon, alleviate and radiate side reaction, induce and urge to induce physiologically active such as leukoregulin.
3, sedation
Pachyman has tangible sedation to the body nervus centralis, can resist being overexcited due to the caffeine, effectively stablizes chronic schizophrenia patient, spiritual manic person's emotion.
4, other functions
Pachyman has the control hepatic injury, prevents gastric ulcer, controls infantile diarrhea, inducing diuresis to remove edema, improve cardiovascular function, make functions such as myocardial contraction is strengthened, anti-cerebral thrombosis cerebral hemorrhage.
The specific embodiment
The preparation of embodiment 1 compound polysaccharide capsule
Prescription:
Method for making: take by weighing Agaricus Blazei Murrill polysaccharide, lentinan, pachyman by weight respectively, mix homogeneously, No. 0 capsule of packing promptly gets.
Side effect such as hypoimmunity that embodiment 2 products treatment tumor patient chemotherapy causes and gastricism
[clinical data]
Clarifying a diagnosis is patient's 20 examples of tumor, patients with gastric cancer 14 examples (operation back convalescence), and patients with lung cancer 6 examples (during the chemicotherapy) are taken above-mentioned complex polysaccharide preparation, observe the curative effect.
[Therapeutic Method]
Diet is still taken these article twice every day, each 1.Took continuously 90 days.
[therapeutic outcome]
1, criterion of therapeutical effect:
Recovery from illness: clinical symptoms all disappears, and it is normal that body function recovers.
Produce effects: therapeutic effect is obvious, and clinical symptoms disappears basically.
Effectively: compare with the symptom before these article of taking, have clear improvement, alleviated the degree of some clinical symptoms.
Invalid: no change before and after the treatment.
2, patient's feedback: in patients with gastric cancer 14 examples, 0 example of fully recovering, produce effects 9 examples, effective 4 examples, invalid 1 example; Total effective rate: 92.9%; In patients with lung cancer 6 examples, 0 example of fully recovering, produce effects 4 examples, effective 1 example, invalid 1 example; Total effective rate: 83.3%.
Toxic and side effects: show in the feedback information according to the patient that untoward reaction appears in no patient.
[model case]
Patient Wang, the man, 63 years old is that pulmonary carcinoma is early stage after diagnosing, after the treatment of reception chemicotherapy, symptoms such as anemia, dizziness, lethargy occur; Simultaneously with gastricisms such as appetite decline, nausea and vomiting.
Curative effect: after taking for two weeks, find that appetite strengthens.So continued to take three months.Gastricisms such as the decline of patient's readme appetite, nausea and vomiting have not had basically; The mental status is good, and dizziness and Anemia alleviate, and quality of the life has had and increases substantially.
The body sub-health state that the treatment of embodiment 3 products causes because of hypoimmunity
[clinical data]
Diagnose 20 clear and definite routine hypoimmunity patients: male 10 examples, women 10 examples, 35 years old mean age, city working clan, life anxiety.Take above-mentioned complex polysaccharide preparation, observe the curative effect.
[Therapeutic Method]
Diet is still taken these article twice every day, each 1.Took continuously 90 days.
[therapeutic outcome]
1, criterion of therapeutical effect:
Recovery from illness: clinical symptoms all disappears, and it is normal that body function recovers.
Produce effects: therapeutic effect is obvious, and clinical symptoms disappears basically.
Effectively: compare with the symptom before these article of taking, have clear improvement, alleviated the degree of some clinical symptoms.
Invalid: no change before and after the treatment.
2, patient's feedback: 17 examples of fully recovering account for 85%; 2 examples that take a turn for the better account for 10%; Effective 1 example accounts for 5%; Invalid 0 example accounts for 0%.The present invention is 85% helping the total cure rate aspect the enhancing immunity.
Toxic and side effects: show in the feedback information according to the patient that untoward reaction appears in no patient.
[model case]
Patient Zhao, man, 38 years old.The city white collar was worked ten six or seven hours every day, and life is nervous, the shortage motion.Symptoms such as appearance has a delicate constitution, lethargy, fatigue and weak, appetite depression, sleep disorder.The situation that has flu to show effect repeatedly and suffer from diarrhoea and show effect repeatedly.
Curative effect: after taking for two weeks, find that appetite strengthens, the mental status takes a turn for the better, and the insomnia situation alleviates.So continued to take three months.Patient's readme has not had above symptom fully.
Claims (4)
1. edible fungi complex polysaccharide health care treatment prescription and preparation method thereof is characterized in that used raw material and parts by weight thereof: Agaricus Blazei Murrill polysaccharide 20-60 part, lentinan 10-30 part, pachyman 5-15 part.
2. a kind of edible fungi complex polysaccharide health care treatment prescription according to claim 1 and preparation method thereof is characterized in that the best proportioning of used raw material and parts by weight thereof: 40 parts of Agaricus Blazei Murrill polysaccharides, 20 parts of lentinan, 10 parts of pachymans.
3. a kind of edible fungi complex polysaccharide health care treatment prescription according to claim 1 and 2 and preparation method thereof; It is characterized in that: used raw material is processed oral formulations such as granule, capsule, tablet, oral liquid by its parts by weight mix homogeneously.
4. a kind of edible fungi complex polysaccharide health care treatment prescription according to claim 1 and 2 and preparation method thereof, it is characterized in that: this prescription helps the enhances human body immunologic function, promotes the hemopoietic function of people's bone marrow; The effectively side effect of tumor remission patient chemotherapy improves the tumor patient quality of the life; Help to improve symptoms such as sub-health population shows has a delicate constitution, lethargy, fatigue and weak, appetite depression, sleep disorder.
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| CN104382030A (en) * | 2014-12-04 | 2015-03-04 | 高秀媛 | Healthcare food for adjusting liver and kidney function and preparation process of healthcare food |
| CN105029395A (en) * | 2014-04-15 | 2015-11-11 | 四川万安石斛产业开发有限公司 | Food, health-caring product or medicine composition enhancing immunity |
| CN106901374A (en) * | 2017-02-16 | 2017-06-30 | 丁强 | A kind of mushroom polysaccharide powder nutraceutical of instant edible |
| CN107198697A (en) * | 2017-06-01 | 2017-09-26 | 青海怡然食品有限公司 | A kind of complex polysaccharide of conditioning subhealthy state and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105029395A (en) * | 2014-04-15 | 2015-11-11 | 四川万安石斛产业开发有限公司 | Food, health-caring product or medicine composition enhancing immunity |
| CN104382030A (en) * | 2014-12-04 | 2015-03-04 | 高秀媛 | Healthcare food for adjusting liver and kidney function and preparation process of healthcare food |
| CN106901374A (en) * | 2017-02-16 | 2017-06-30 | 丁强 | A kind of mushroom polysaccharide powder nutraceutical of instant edible |
| CN107198697A (en) * | 2017-06-01 | 2017-09-26 | 青海怡然食品有限公司 | A kind of complex polysaccharide of conditioning subhealthy state and preparation method thereof |
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Application publication date: 20121121 |