CN102813199A - Health-care food for prevention and adjuvant therapy of cancer, three-high disease and immunity strengthening - Google Patents
Health-care food for prevention and adjuvant therapy of cancer, three-high disease and immunity strengthening Download PDFInfo
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- CN102813199A CN102813199A CN201210321648XA CN201210321648A CN102813199A CN 102813199 A CN102813199 A CN 102813199A CN 201210321648X A CN201210321648X A CN 201210321648XA CN 201210321648 A CN201210321648 A CN 201210321648A CN 102813199 A CN102813199 A CN 102813199A
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Abstract
The invention discloses a health-care food for prevention and adjuvant therapy of cancer and three-high disease and immunity strengthening. The health-care food is prepared by, by weight, propolis 3-10 parts, ginkgo leaves 5-15 parts, grifola frondosa 5-15 parts, shell-broken spore powder 5-10 parts, medlar 10-20 parts and poria cocos 10-20 parts. The health-care food is rich in nutrition, can strengthen immunity and prevent and cure the cancer, diabetes mellitus, hyperlipidemia and hypertension in an adjuvant mode, and is safe, free of toxic and side effects and convenient to take.
Description
Technical field
The invention belongs to field of health care food, be specifically related to the health food of a kind of prevention and auxiliary for treating cancer, three high diseases (hypertension, high fat of blood, hyperglycaemia) and enhance immunity power.
Background technology
Serious day by day along with environmental pollution, people's rhythm of life is accelerated, and psychological pressure strengthens, and the incidence of disease of cancer is increasingly high.Treatment for cancer is present difficult medical problem in the world, especially for patient with advanced cancer, does not still have specific drug to save patient's misery, and the death rate is in first of all kinds of diseases, and the prevention of cancer and treatment just seem particularly important.Improving immunity of human body itself, resist cell mutation, thereby suppress the formation of tumour, is the essential measure that ensures the safety of human life and not threatened by cancer.
" three height " that hypertension, high fat of blood, hyperglycaemia promptly it has often been said, high fat of blood can cause blood vessel embolism; Hypertension can cause cerebral hemorrhage and rupture of blood vessel in brain; Hyperglycaemia can cause diabetes.The World Health Organization once clearly proposed, and prevented that the first line of defence of cardiovascular disease from reducing exactly " three height " and control " three height ".
At present the medicine of treatment cancer and three high diseases is more, and prophylaxis of cancer and three high diseases be mainly health products, but the most function singleness of health products in the market is badly in need of the health products of a kind of comprehensive prevention effect.
Summary of the invention
The health food that the purpose of this invention is to provide a kind of prevention and auxiliary for treating cancer, three high diseases and enhance immunity power, its can enhance immunity power, and cancer, hypertension, high fat of blood, hyperglycaemia had prevention and supplemental treatment effect.
Technical scheme of the present invention is: the health food of a kind of prevention and auxiliary for treating cancer, three high diseases and enhance immunity power; It is characterized in that, process: propolis 3-10, ginkgo leaf 5-15, grifola frondosus 5-15, ganoderma spove powder 5-10, matrimony vine 10-20, Poria cocos 10-20 by the raw material of following weight parts.
Preferred weight part of above-mentioned raw materials is: propolis 8, ginkgo leaf 10, grifola frondosus 10, ganoderma spove powder 5, matrimony vine 15, Poria cocos 15.
Said ganoderma spove powder is that sporoderm-broken rate is the commercial goods of 94-97%.
Preparation method: get raw material by above-mentioned weight portion, ginkgo leaf, grifola frondosus, matrimony vine and Poria cocos are crushed to the fine powder that particle diameter is 10-15 μ m, gained fine powder water is decocted three times; Each 0.5-1.5 hour; Filtering liquid medicine is condensed into the thick paste that relative concentration is 1.30-1.45 (60 ℃) with gained filtrating, and adding propolis and ganoderma spove powder mix in the thick paste; Process capsule according to conventional method, every active constituent content is 0.3g.
Instructions of taking: warm boiling water is taken, every day twice, each two.It is a course of treatment that health products of the present invention are taken 20 days continuously.
The mechanism of action of each raw material:
Propolis: bitter, hot, cold, return spleen, stomach warp.Qi-restoratives for oral administration is weak, change turbid fat, only quench one's thirst.In modern medicine detection propolis, contain the flavone compound more than 70 kinds, flavone compound has many-sided physiology and pharmacological action, can help human body to prevent and treat multiple disease, makes the various function normalizations of body, enhancingization.Propolis mainly contains immunoregulatory effect as health food, also have auxiliary anti-oxidant, regulate blood fat, blood pressure, blood sugar, auxiliary protection gastric mucosa, antibiotic, anti-inflammatory, multiple function such as antitumor.
Ginkgo leaf: sweet, bitter, puckery, flat.The thoughts of returning home, lung channel.Can extract the effective medicinal ingredient of kind more than 160 in the ginkgo leaf, wherein, 35 kinds of flavone compounds; 7 kinds of amino acid/11s are multiple with trace element, can strengthen antiotasis, coronary artery dilator, softening blood vessel, improve vasopermeability; Bring high blood pressure down, reduce blood fat and cholesterol; Anti-platelet aggregation, minimizing thrombosis reduce endovascular HDL-C (HDL-C), triglycerides (TG), thereby reach effect hypotensive, reducing blood lipid.
Grifola frondosus: nutritious; Its nutrient content contains protein 25.2 grams, dietary fiber 33.7 grams, carbohydrate 21.4 grams in detecting the dried grifola frondosus of each hectogram; Be rich in the minerals and vitamins of multiple beneficial, wherein VE109.7 milligram, VB11.47 milligram, VB20.72 milligram, VC17.0 milligram, 4.5 milligrams of carrotene; Can promote child's torso to grow up healthy and sound and intelligence development, be described as " edible mushroom king " and " North China genseng ".Grifola frondosus contains higher Se content; Effect with the cancer of resisting, especially contained grifolan (Grifolan) is main with beta glucan (glucan); These active glucans can significantly suppress growth of tumor through the activated immune function, and it is again fabulous immunomodulator simultaneously.
Glossy ganoderma: glossy ganoderma is the treasure in China's medical treasure-house, enjoys the good reputation of " promoting longevity ", " bowl spares benefit vital essence increases wisdom ", " alive for evermore " since ancient times.The active ingredient of glossy ganoderma and lucidum spore powder is: GL-B, triterpenes, protein, polypeptide, amino acid, nucleoside compound, organic germanium, trace element and vitamin etc.; Wherein GL-B is one of composition the most effectively in the glossy ganoderma; Has pharmacologically active widely; Can improve immunity of organisms, alleviate toxic and side effects of chemoradiotherapy, the various malignant tumours of prevention, treatment and supplemental treatment.
Matrimony vine: it is sweet to distinguish the flavor of; Property is put down.Return liver, kidney, lung channel.Function: nourishing the liver; Nourshing kidney; Moistening lung.Cure mainly: caused by liver and kidney deficiency; Have a dizzy spell; Visual unclear; Soreness and weakness of waist and knees; Impotence and seminal emission; Cough due to consumptive disease; Quench one's thirst and draw drink.Modern study, matrimony vine have the blood sugar of reduction, lipotropy, and can antiatherosclerosis.
Poria cocos: sweet, light, the property of distinguishing the flavor of is flat, goes into the heart, lung, the spleen channel.Be used as medicine have clearing damp and promoting diuresis, the function of beneficial spleen and stomach, antitoxic heart-soothing and sedative.Can control difficult urination, the oedema turgor, phlegm and retained fluid is coughed contrary, and it is contrary to vomit, and vomiting during early pregnancy is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.Modern medicine study: tuckahoe extracts contains pachymaran, glucose, protein, amino acid, organic acid, fat, lecithin, adenine, choline, ergosterol, plurality of enzymes and sylvite; Ability enhancing body immunologic function; Diuresis is arranged, can increase electrolytical discharges such as potassium, sodium, chlorine in the urine; Effects such as calmness and protection liver, the generation that suppresses ulcer, hypoglycemic, anti-radiation are arranged.
Pachymaran wherein has significantly antitumor and protects the liver dirty effect.
Be better than the medication principle according to the dietary therapy of Chinese medicine, the present invention's employing medicine food homologous raw materials of filling a prescription, select for use the propolis qi-restoratives weak, change turbid fat, only quench one's thirst, enhance immunity power; Hypotensive, the reducing blood lipid of ginkgo leaf; The grifola frondosus qi-restoratives consolidates, kidney-nourishing is anticancer, inducing diuresis for removing edema; Glossy ganoderma antitoxic heart-soothing and sedative, spleen benefiting and stimulating the appetite, elimination fatigue; Matrimony vine nourishing the liver, nourshing kidney, moistening lung; Poria cocos clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative; These six kinds of raw material synergies play and build up health, and improve immunity, and the opposing cell mutation suppresses tumour, and hypotensive, reducing blood lipid, hypoglycemic simultaneously improves vasopermeability, reduces thrombotic function.
The invention has the beneficial effects as follows: health food of the present invention is nutritious, can enhance immunity power, and prevention and auxiliary for treating cancer, diabetes, high fat of blood, hypertension, and safety has no side effect taking convenience.
Suffer from diabetes, high fat of blood, hypertensive patient 50 examples simultaneously, take medicine for treatment blood fat health and antisterone three months, efficient is 85%; Other has and suffers from diabetes simultaneously, high fat of blood, hypertensive patient 50 examples; On the basis of taking identical treatment medication blood fat health and antisterone; Add health products of the present invention (embodiment 1 prescription), every day twice, each two; Taking efficient after three months is 94%, explains that health products adjuvant therapy of diabetes of the present invention, high fat of blood, hypertension effect are remarkable.
Further specify beneficial effect of the present invention below in conjunction with experimental data:
Experiment purpose: inquire into the anti-sudden change and the effect of enhance immunity power of health products of the present invention.
Experimental technique: select for use mouse to resist sudden change and function of enhancing immunity test.
1. material
1.1 laboratory sample: prescription sees that the health products of the present invention of embodiment 1, human body recommended amounts are every day 2 times, each 2, and become body weight for humans press 60Kg calculating, amount to dosage 0.02g/kg.BW.
1.2 animal used as test: clean type Kunming kind female mice, body weight 18-22 gram.Experiment condition is a barrier environment, temperature 22-24 ℃, and humidity 54-56%.Three dose groups and a blank group are established in experiment, are low dose group (0.1g/kg.BW) with 5 times of human body recommended amounts, and 10 times is middle dose groups (0.2g/kg.BW), and 30 times is high dose group (0.6g/kg.BW).Sample thief 1g, 2g, 6g adding distil water are settled to 200ml respectively, are tried mouse stomach respectively, irritate stomach every day once, irritate the long-pending 0.2ml/10g.BW of being of body of stomach, and control group is irritated with isopyknic distilled water, and the time is 20 days.
2. experimental technique
2.1 anti-mutating experiment
According to " the health food function assessment assessment process and the method for inspection ", carry out Ames experiment and endoxan and cause the experiment of mouse Bone marrow cells micronucleus rate.
2.2 function of enhancing immunity experiment
By Ministry of Public Health's " health food check with assessment technique standard " (2003 editions), carry out mouse spleen lymphocyte transformation experiment, antibody-producting cell detections, the mensuration of HD50 value (HC50), mouse carbon that mouse internal organs/weight ratio pH-value determination pH, delayed allergy (DTH), ConA induce and clean up experiment, Turnover of Mouse Peritoneal Macrophages and engulf that chicken red blood cell is tested, NK cytoactive determination experiment carries out functional evaluation.
3. result of the test
3.1 anti-mutating experiment result
3.1.1Ames experiment
Table 1Ames experimental result (clump count/ware relatively)
Visible by table 3, preparation of the present invention is to TA98, TA100 two strain experimental strains, adds under the S-9 situation and do not add under the situation of S-9, presents antimutagenic effect (* variance analysis check compare with positive controls P ﹤ 0.05).
3.1.2 the influence of the mouse Bone marrow cells micronucleus that health products of the present invention bring out endoxan
The influence of the mouse Bone marrow cells micronucleus that table 2 health products of the present invention bring out endoxan
Group | Number of animals (only) | The observation of cell number | The micronucleus number | Micronuclear rates (‰) |
Negative control group | 10 | 10×1000 | 54 | 5.4 |
Positive controls | 10 | 10×1000 | 403 | 40.3 |
Visible by table 4, health products of the present invention are starkly lower than positive controls to the mouse Bone marrow cells micronucleus rate that endoxan brings out, and check P ﹤ 0.05 with the positive controls Poisson distribution, have significant difference.
Conclusion: according to " the health food function assessment assessment process and the method for inspection ", health products of the present invention all present the inhibitory action to positive thing mutagenesis to TA98, TA100 two strain experimental strains under the situation that adds and do not add S-9; Mouse Bone marrow cells micronucleus rate due to obviously the reduction endoxan brings out.
3.2 the immunity function experimental result sees the following form
Table 3 health food of the present invention is to effect of immunologic function overall assessment table (X ± S)
Annotate:
*Compared significant difference (P ﹤ 0.05) with control group
Result of the test shows: per os gives the health products of the present invention 20 days of each dosage of mouse, and middle dose groups can significantly improve the ability (P<0.05) that mouse monokaryon one macrophage carbon is cleaned up, and obviously strengthens the mouse delayed allergy; High dose group can obviously strengthen ability, the mouse delayed allergy that mouse monokaryon one macrophage carbon cleans up and improve the HD50 value of mouse.Compare with control group, health products of the present invention do not have obvious influence (P ﹥ 0.05) to weight of mice, spleen/body weight ratio, thymus gland/body weight ratio, lymphocyte transformation ability, antibody-producting cell number, the ability of macrophage phagocytic chicken red blood cell, NK cytoactive.Show that health products of the present invention have the function of enhance immunity power.
Low dose group | 10 | 10×1000 | 395 | 39.5 |
Middle dose groups | 10 | 10×1000 | 336 | 33.6 * |
High dose group | 10 | 10×1000 | 269 | 26.9 * |
The specific embodiment
Embodiment 1
Proportioning (weight portion): propolis 8, ginkgo leaf 10, grifola frondosus 10, ganoderma spove powder 5, matrimony vine 15, Poria cocos 15.Wherein ganoderma spove powder is that sporoderm-broken rate is 94% commercial goods.
Preparation method: get ginkgo leaf, grifola frondosus, matrimony vine and the Poria cocos of above-mentioned weight portion, be crushed to the fine powder that particle diameter is 10-15 μ m, gained fine powder water is decocted three times; Each 1 hour; Filtering liquid medicine is condensed into the thick paste that relative concentration is 1.35 (60 ℃) with gained filtrating, and the propolis and the ganoderma spove powder that add above-mentioned weight portion in the medicinal extract mix; Process soft capsule according to conventional method, every active constituent content is 0.3g.
Embodiment 2
Proportioning (weight portion): propolis 10, ginkgo leaf 15, grifola frondosus 10, ganoderma spove powder 6, matrimony vine 20, Poria cocos 10.Wherein ganoderma spove powder is that sporoderm-broken rate is 95% commercial goods.
Preparation method: get ginkgo leaf, grifola frondosus, matrimony vine and the Poria cocos of above-mentioned weight portion, be crushed to the fine powder that particle diameter is 10-15 μ m, gained fine powder water is decocted three times; Each 1 hour; Filtering liquid medicine is condensed into the thick paste that relative concentration is 1.30 (60 ℃) with gained filtrating, and the propolis and the ganoderma spove powder that add above-mentioned weight portion in the medicinal extract mix; Process soft capsule according to conventional method, every active constituent content is 0.3g.
Embodiment 3
Proportioning (weight portion): propolis 3, ginkgo leaf 10, grifola frondosus 15, ganoderma spove powder 10, matrimony vine 10, Poria cocos 15.Wherein ganoderma spove powder is that sporoderm-broken rate is 97% commercial goods.
Preparation method: ginkgo leaf, grifola frondosus, matrimony vine and the Poria cocos of getting above-mentioned weight portion; Be crushed to the fine powder that particle diameter is 10-15 μ m, gained fine powder water decocted three times each 1 hour; Filtering liquid medicine is condensed into the thick paste that relative concentration is 1.45 (60 ℃) with gained filtrating.The propolis and the ganoderma spove powder that add above-mentioned weight portion in the medicinal extract mix, and process hard shell capsules according to conventional method, and every active constituent content is 0.3g.
Claims (5)
1. the health food of a prevention and auxiliary for treating cancer, three high diseases and enhance immunity power; It is characterized in that, process: propolis 3-10, ginkgo leaf 5-15, grifola frondosus 5-15, ganoderma spove powder 5-10, matrimony vine 10-20, Poria cocos 10-20 by the raw material of following weight parts.
2. health food as claimed in claim 1 is characterized in that, is processed by the raw material of following weight parts: propolis 8, ginkgo leaf 10, grifola frondosus 10, ganoderma spove powder 5, matrimony vine 15, Poria cocos 15.
3. according to claim 1 or claim 2 health food is characterized in that said ganoderma spove powder sporoderm-broken rate is 94-97%.
4. a method for preparing claim 1 or 2 said health foods is characterized in that, gets raw material by claim 1 or 2 said weight portions; Ginkgo leaf, grifola frondosus, matrimony vine and Poria cocos are crushed to the fine powder that particle diameter is 10-15 μ m; Gained fine powder water is decocted three times, each 0.5-1.5 hour, filtering liquid medicine; Relative concentration was the thick paste of 1.30-1.45 when gained filtrating was condensed into 60 ℃, and adding propolis and ganoderma spove powder mix and process capsule in the thick paste.
5. preparation method as claimed in claim 4 is characterized in that, said ganoderma spove powder sporoderm-broken rate is 94-97%.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104187617A (en) * | 2014-07-30 | 2014-12-10 | 溧阳市天目湖保健品有限公司 | Health food capable of enhancing immunity and preparation method thereof |
CN104187618A (en) * | 2014-08-02 | 2014-12-10 | 溧阳市天目湖保健品有限公司 | Health food with blood lipid regulating function and preparation method of health food |
CN104351761A (en) * | 2014-10-17 | 2015-02-18 | 无锡许仙草灵芝农民专业合作社 | Ultrahigh-pressure jet flow reishi shell-broken spore powder and oral liquid process unit |
CN109864307A (en) * | 2017-12-04 | 2019-06-11 | 山东睿鹰先锋制药有限公司 | A kind of composition for capableing of strengthen immunity |
CN112790378A (en) * | 2021-02-01 | 2021-05-14 | 陈礼平 | Edible fungus functional food with effect of reducing hypertension, hyperglycemia and hyperlipidemia |
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CN1404751A (en) * | 2000-12-25 | 2003-03-26 | 吴跃飞 | Health-care vermicelli, bean-made noodles and bean-made sheet jelly |
CN101537013A (en) * | 2008-03-18 | 2009-09-23 | 林华型 | Application of nanometer polysaccharide for preparing antineoplastic medicament |
CN102113584A (en) * | 2011-03-15 | 2011-07-06 | 黄选明 | Health preserving tea |
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2012
- 2012-09-03 CN CN201210321648XA patent/CN102813199B/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1404751A (en) * | 2000-12-25 | 2003-03-26 | 吴跃飞 | Health-care vermicelli, bean-made noodles and bean-made sheet jelly |
CN101537013A (en) * | 2008-03-18 | 2009-09-23 | 林华型 | Application of nanometer polysaccharide for preparing antineoplastic medicament |
CN102113584A (en) * | 2011-03-15 | 2011-07-06 | 黄选明 | Health preserving tea |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104187617A (en) * | 2014-07-30 | 2014-12-10 | 溧阳市天目湖保健品有限公司 | Health food capable of enhancing immunity and preparation method thereof |
CN104187618A (en) * | 2014-08-02 | 2014-12-10 | 溧阳市天目湖保健品有限公司 | Health food with blood lipid regulating function and preparation method of health food |
CN104351761A (en) * | 2014-10-17 | 2015-02-18 | 无锡许仙草灵芝农民专业合作社 | Ultrahigh-pressure jet flow reishi shell-broken spore powder and oral liquid process unit |
CN104351761B (en) * | 2014-10-17 | 2016-08-31 | 无锡许仙草灵芝农民专业合作社 | A kind of superhigh pressure water jet Ganoderma spore powder with cellular wall broken and oral liquid process unit |
CN109864307A (en) * | 2017-12-04 | 2019-06-11 | 山东睿鹰先锋制药有限公司 | A kind of composition for capableing of strengthen immunity |
CN112790378A (en) * | 2021-02-01 | 2021-05-14 | 陈礼平 | Edible fungus functional food with effect of reducing hypertension, hyperglycemia and hyperlipidemia |
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