CN104187617A - Health food capable of enhancing immunity and preparation method thereof - Google Patents

Health food capable of enhancing immunity and preparation method thereof Download PDF

Info

Publication number
CN104187617A
CN104187617A CN201410366957.8A CN201410366957A CN104187617A CN 104187617 A CN104187617 A CN 104187617A CN 201410366957 A CN201410366957 A CN 201410366957A CN 104187617 A CN104187617 A CN 104187617A
Authority
CN
China
Prior art keywords
ginkgo biloba
health food
extract
biloba extract
fructus lycii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410366957.8A
Other languages
Chinese (zh)
Inventor
彭江晨
王爱平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TIANMUHU HEALTH PRODUCT CO Ltd LIYANG
Original Assignee
TIANMUHU HEALTH PRODUCT CO Ltd LIYANG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TIANMUHU HEALTH PRODUCT CO Ltd LIYANG filed Critical TIANMUHU HEALTH PRODUCT CO Ltd LIYANG
Priority to CN201410366957.8A priority Critical patent/CN104187617A/en
Publication of CN104187617A publication Critical patent/CN104187617A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a health food capable of enhancing immunity and a preparation method thereof, which belong to the field of health food. According to a formula, the health food comprises the following ingredients in parts by weight: 30-50 parts of fructus lycii extracts, 30-50 parts of poria cocos extracts, and 10-30 parts of gingko flavonoids. According to the invention, three kinds of Chinese herb extracts are extracted by using a new ultrasonic extraction method, and then the three kinds of Chinese herb extracts are compatibly used and cooperatively acted, so that the health food plays a role in enhancing immunity better. The health food emphatically takes the crowd as the research object, and selects a capsule as a dosage form of products by taking function, absorption and stability and the like into consideration, therefore, the health food has the characteristics of high bioavailability, easiness for taking, and the like.

Description

A kind ofly can improve health food of immunity and preparation method thereof
Technical field
The present invention relates to a kind of health food, especially a kind ofly take Chinese herbal medicine and can improve health food of immunity and preparation method thereof as what raw material was made.
Background technology
Immunity is the defense mechanism of human body self, is human body identification and any foreign matter (virus, bacterium etc.) of eliminating external intrusion; Process the ability of self cell and identification and processing vivo mutations cell and the virus infected cell of old and feeble, damage, dead, sex change.Modern immunology thinks, immunity is human body identification and the physiological reaction of getting rid of " dissident ".From color therapy, human body needs the light wave of various frequency 300 ~ 700 nanometers, maintains healthy and existence.
Immunity can be divided into two classes: the 1. innate immunity: the innate immunity (Natural immunity), claim again congenital immunity, and refer to that a people or Yi Ge colony have an instinct for the immunity having.A lot of diseases are that domestic or wild animal all can infect, but the mankind but have natural immunity to these diseases; And the contagious a lot of diseases of the mankind, some animal but has immunity.Certain race of the mankind may have immunity to some disease, but other races may just be infected than being easier to.In agnate people, perhaps someone has immunity to a kind of disease, and agnate other people be easily infected.2. acquired immunity: acquired immunity (Acquired immunity), claim again acquired immunity, be in life process, naturally to obtain after people is born, or with passive the obtaining of method of human assistance.Refer to that antibody, protein in blood produce, and can hit the antigen (antigen) (foreign substance) in health.Every kind of antibody can only be protected a kind of antigen of body-defence.Antibody belongs to the immune system part of health.Immune other parts comprise marrow, and marrow is various leukocytic for manufacturing, and leucocyte protection health is avoided bacterium and infected; Lymph gland is leukocytic for manufacturing, and these leucocytes produce antibody in turn; Thymus gland is used for manufacturing thymosin extrasin, and thymosin extrasin is a kind of hormone that stimulates some leucocyte maturation; Be used for regulating cell factor and the protein of multiple leucocyte activity.Acquired immunity power can be initiatively, can be also passive.
The performance of hypoimmunity: it is exactly liable to illness that hypoimmunity the most directly shows.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, the performance such as malnutritive, One's spirits are drooping, fatigue and weak, appetite reduction, sleep-disorder, sick, have an injection and take medicine the normal potluck that just gets married.Each sickly all will could recover for a long time, and usually outbreak repeatedly.If things go on like this can cause health and intelligence development bad, also easily bring out major disease.
Along with the develop rapidly of China's economy, the raising of national life level, people's health care consciousness is more and more stronger, and suitably taking some health food disease preventing and treating and keeping fit becomes the people of the world's important means.Plant extracts appears at health products trade more and more in recent years, how to extract efficiently separation, improves extract quality and output and by insider, is paid close attention to.And ultrasonic extraction can effectively improve extraction separation rate, shorten extraction time, cost-saving, the Quality and yield that even can also improve product, this emerging extraction method will have very large prospect in field of plant extraction.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, provide a kind of include Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT can improve health food of immunity and preparation method thereof.
The object of the present invention is achieved like this: a kind ofly can improve immunity health food, its constituent comprises (weight portion): Fructus lycii P.E: 30~50 parts, tuckahoe extracts: 30~50 parts, GINKGO BILOBA EXTRACT: 10~30 parts, the significant composition of described Fructus lycii P.E is LBP-X, the content of this LBP-X is not less than 30.0%, and component is in detail:
LBP-X >=30.0%;
Moisture≤5.0%;
Ash content≤5.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤1.0mg/kg;
Plumbous (in Pb)≤2.0mg/kg;
The significant composition of described tuckahoe extracts is pachymaran, and the content of this pachymaran is not less than 20.0%, and component is in detail:
Pachymaran >=20.0%;
Moisture≤8.0%;
Ash content≤6.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤0.5mg/kg;
Plumbous (in Pb)≤1.0mg/kg;
Copper (in Au)≤10.0mg/kg;
Sulfur dioxide residual quantity≤150mg/kg;
Described GINKGO BILOBA EXTRACT is ginkgo biloba p.e, and the content of this GINKGO BILOBA EXTRACT is not less than 24.0%, and component is in detail:
GINKGO BILOBA EXTRACT >=24.0%;
Moisture≤5.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤1.0mg/kg;
Residue on ignition≤0.8%.
Further, optimization formula composition weight portion of the present invention is: 40 parts, and tuckahoe extracts: 40 parts, GINKGO BILOBA EXTRACT: 20 parts, the significant composition of described Fructus lycii P.E is LBP-X, and the content of this LBP-X is not less than 30.0%, component is in detail:
LBP-X >=30.0%;
Moisture≤5.0%;
Ash content≤5.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤1.0mg/kg;
Plumbous (in Pb)≤2.0mg/kg;
The significant composition of described tuckahoe extracts is pachymaran, and the content of this pachymaran is not less than 20.0%, and component is in detail:
Pachymaran >=20.0%;
Moisture≤8.0%;
Ash content≤6.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤0.5mg/kg;
Plumbous (in Pb)≤1.0mg/kg;
Copper (in Au)≤10.0mg/kg;
Sulfur dioxide residual quantity≤150mg/kg;
Described GINKGO BILOBA EXTRACT is ginkgo biloba p.e, and the content of this GINKGO BILOBA EXTRACT is not less than 24.0%, and component is in detail:
GINKGO BILOBA EXTRACT >=24.0%;
Moisture≤5.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤1.0mg/kg;
Residue on ignition≤0.8%.
The present invention is a kind of can improve immunity health food, is made into capsule.
The present invention can improve the raw material disposal method of the health food of immunity, it is characterized in that its technique comprises the following steps:
1, the preparation of Fructus lycii P.E: the fruit of Chinese wolfberry being cleaned and dried, pulverize, cross 50~60 mesh sieves, is 40kHz in supersonic frequency, power is 200w, and temperature is 60 ℃, and 70% the ethanol of take is to extract solvent, solid-liquid ratio is 1:20, ultrasonic extraction 30min, and then centrifugal concentrating is dried to obtain LBP-X;
2, the preparation of tuckahoe extracts: Poria cocos being cleaned and dried, pulverize, cross 20~60 mesh sieves, is 40kHz in supersonic frequency, power is 320w, and 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:10, temperature is 25 ℃, ultrasonic extraction 20min, and then centrifugal concentrating is dried to obtain pachymaran;
3, the preparation of GINKGO BILOBA EXTRACT: ginkgo leaf being cleaned and to be dried, pulverize, cross 50~60 mesh sieves, is 40kHz in supersonic frequency, and power is 320w, and temperature is 30 ℃, 70% the ethanol of take is to extract solvent, solid-liquid ratio is 1:15, ultrasonic extraction 10min.Repeat to extract twice, then centrifugal concentrating is dried to obtain GINKGO BILOBA EXTRACT.
A kind of preparation method that can improve immunity health food of the present invention, comprises following processing step:
1, by Fructus lycii P.E recited above, tuckahoe extracts, GINKGO BILOBA EXTRACT, will check in accordance with regulations, qualified Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT are standby;
2, mixing of materials:, drop in blender after Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT batching by the proportioning described in claim 1, mix 25~35min;
3, granulate: with wetting agent softwood processed, cross 20~28 mesh sieve wet granular processed;
4, dry: wet granular is in 50 ℃~70 ℃ heated-air dryings;
5, whole grain: dry particle is crossed the whole grain of 18~22 mesh sieves;
6, manufactured goods: filling capsule, every dose of content 0.25~0.35g;
7, packing warehouse-in.
Further, described wetting agent is that 5% polyethylene adjoins pyrrolidone (PVPK30) ethanolic solution.
The present invention in conjunction with physicochemical property, considers from function, absorption, stability etc. are many-sided, selects capsule, tablet, granule all to can be used as product forms.Take crowd emphatically as research object, then make capsule as the formulation of product through rational technique, there is the features such as bioavilability is high, taking convenience.
Matrimony vine is the plant of eggplant order Solanaceae Lycium (Lycium), and fruit claims the fruit of Chinese wolfberry, and tender leaf claims matrimony vine head, and frequent species is matrimony vine (Lycium chinense Miller), and main medicinal kind is lycium barbarum (Lycium barbarum L.).Matrimony vine has the blood sugar of reduction, lipotropy, and can antiatherosclerosis.
Poria cocos, claims that again jade is clever, Fu is clever, Wan Linggui, Fu Tu.The dry sclerotia of Shi Ni shelf fungus section fungi Poria cocos, often colonizes on pine roots, and shape is as sweet potato, spherical, crust light brown or pitchy, and inner pink colour or white, be called PORIA ALBA or cloud Siberian cocklebur after refining.Poria cocos is similar to smilax title, therefore easily mixed.Smilax is the root of Smilacaceae plant smilacis glabra (Smilax glabra), and crust yellowish-brown or taupe are completely irrelevant with Poria cocos.Poria cocos slightly sweet flavor is flat, enters the heart, lung, the spleen channel.There is eliminating dampness and diuresis, strengthening the spleen and stomach, the effect of antitoxic heart-soothing and sedative.
Ginkgo leaf (formal name used at school: Ginkgo biloba) be a kind of plant with very high medical value.Ginkgo, another name gingko, Gong Sunshu, belong to gymnosperm, and its fellow disciple's every other plant all becomes extinct, is called as " Relict Plant ".Ginkgo leaf be recognized in the worldly control, the optimal pharmaceutical compositions of anti-cardiovascular and cerebrovascular disease.Mildly bitter flavor, property is flat, there is the beneficial heart, promoting blood circulation and stopping pain, astringe the lung relieving asthma, the effect of dampness elimination antidiarrheal.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1:
1. prepare according to the following steps Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT:
(1) preparation of Fructus lycii P.E: the fruit of Chinese wolfberry being cleaned and dried, pulverize, cross 50~60 mesh sieves, is 40kHz in supersonic frequency, power is 200w, and temperature is 60 ℃, and 70% the ethanol of take is to extract solvent, solid-liquid ratio is 1:20, ultrasonic extraction 30min, and then centrifugal concentrating is dried to obtain LBP-X;
(2) preparation of tuckahoe extracts: Poria cocos being cleaned and dried, pulverize, cross 20~60 mesh sieves, is 40kHz in supersonic frequency, power is 320w, and 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:10, temperature is 25 ℃, ultrasonic extraction 20min, and then centrifugal concentrating is dried to obtain pachymaran;
(3) preparation of GINKGO BILOBA EXTRACT: ginkgo leaf is cleaned and dried, pulverize, crossing 50~60 mesh sieves, is 40kHz in supersonic frequency, and power is 320w, temperature is 30 ℃, 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:15, ultrasonic extraction 10min, repeat to extract twice, then centrifugal concentrating is dried to obtain GINKGO BILOBA EXTRACT.
2. by following requirement check Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT, qualified is standby;
Each composition of Fructus lycii P.E requires:
LBP-X >=30.0%, moisture≤5.0%, ash content≤5.0%, heavy metal≤10mg/kg, arsenic (in As)≤1.0mg/kg, plumbous (in Pb)≤2.0mg/kg;
Each composition of tuckahoe extracts requires:
Pachymaran >=20.0%, moisture≤8.0%, ash content≤6.0%, arsenic (in As)≤0.5mg/kg, plumbous (in Pb)≤1.0mg/kg, copper (in Au)≤10.0mg/kg, sulfur dioxide residual quantity≤150mg/kg;
Each composition of ginkgo biloba extract requires:
GINKGO BILOBA EXTRACT >=24.0%, moisture≤5.0%, heavy metal≤10mg/kg, arsenic (in As)≤1.0mg/kg, residue on ignition≤0.8%.
3. extract Fructus lycii P.E 40g, tuckahoe extracts 40g, GINKGO BILOBA EXTRACT 20g, in 300,000 grades of clean areas, drops in V-type blender, mixes 30min, guarantees evenly.
4. in 300,000 grades of clean areas, take 5% polyvinylpyrrolidone (PVPK30) as wetting agent softwood processed, cross 24 mesh sieve wet granular processed.
5. in 300,000 grades of clean areas, wet granular is in 60 ℃ of heated-air dryings.
6. in 300,000 grades of clean areas, dry particle is crossed the whole grain of 20 mesh sieves.
7. capsule is filling: in 300,000 grades of clean areas, with capsule filler filling capsule, every capsules content 0.30g, should note monitoring product content uniformity during filling, is controlled in disparity range.
8. capsule polishing: in 300,000 grades of clean areas, remove the fine powder that sticks to capsule surface with polishing machine, sieve removes defective work simultaneously.
9. inner packing: in 300,000 grades of clean areas, inner packing adopts the oral stable medicinal polythene bottle with high density packing that meets YBB00122002 standard-required, 100 every bottle.
10. external packing: middle package paper box, 1 bottle, every box, large packing adopts corrugated case.
11. checks: check according to related standards.
12. warehouse-ins: product is through putting in storage after the assay was approved.
Embodiment 2:
1. prepare according to the following steps Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT:
(1) preparation of Fructus lycii P.E: the fruit of Chinese wolfberry being cleaned and dried, pulverize, cross 50~60 mesh sieves, is 40kHz in supersonic frequency, power is 200w, and temperature is 60 ℃, and 70% the ethanol of take is to extract solvent, solid-liquid ratio is 1:20, ultrasonic extraction 30min, and then centrifugal concentrating is dried to obtain LBP-X;
(2) preparation of tuckahoe extracts: Poria cocos being cleaned and dried, pulverize, cross 20~60 mesh sieves, is 40kHz in supersonic frequency, power is 320w, and 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:10, temperature is 25 ℃, ultrasonic extraction 20min, and then centrifugal concentrating is dried to obtain pachymaran;
(3) preparation of GINKGO BILOBA EXTRACT: ginkgo leaf is cleaned and dried, pulverize, crossing 50~60 mesh sieves, is 40kHz in supersonic frequency, and power is 320w, temperature is 30 ℃, 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:15, ultrasonic extraction 10min, repeat to extract twice, then centrifugal concentrating is dried to obtain GINKGO BILOBA EXTRACT.
2. by following requirement check Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT, qualified is standby;
Each composition of Fructus lycii P.E requires:
LBP-X >=30.0%, moisture≤5.0%, ash content≤5.0%, heavy metal≤10mg/kg, arsenic (in As)≤1.0mg/kg, plumbous (in Pb)≤2.0mg/kg;
Each composition of tuckahoe extracts requires:
Pachymaran >=20.0%, moisture≤8.0%, ash content≤6.0%, arsenic (in As)≤0.5mg/kg, plumbous (in Pb)≤1.0mg/kg, copper (in Au)≤10.0mg/kg, sulfur dioxide residual quantity≤150mg/kg;
Each composition of ginkgo biloba extract requires:
GINKGO BILOBA EXTRACT >=24.0%, moisture≤5.0%, heavy metal≤10mg/kg, arsenic (in As)≤1.0mg/kg, residue on ignition≤0.8%.
3. extract Fructus lycii P.E 30g, tuckahoe extracts 30g, GINKGO BILOBA EXTRACT 10g, in 300,000 grades of clean areas, drops in V-type blender, mixes 25min, guarantees evenly.
4. in 300,000 grades of clean areas, take 5% polyvinylpyrrolidone (PVPK30) as wetting agent softwood processed, cross 20 mesh sieve wet granular processed.
5. in 300,000 grades of clean areas, wet granular is in 50 ℃ of heated-air dryings.
6. in 300,000 grades of clean areas, dry particle is crossed the whole grain of 18 mesh sieves.
7. capsule is filling: in 300,000 grades of clean areas, with capsule filler filling capsule, every capsules content 0.25g, should note monitoring product content uniformity during filling, is controlled in disparity range.
8. capsule polishing: in 300,000 grades of clean areas, remove the fine powder that sticks to capsule surface with polishing machine, sieve removes defective work simultaneously.
9. inner packing: in 300,000 grades of clean areas, inner packing adopts the oral stable medicinal polythene bottle with high density packing that meets YBB00122002 standard-required, 120 every bottle.
10. external packing: middle package paper box, 1 bottle, every box, large packing adopts corrugated case.
11. checks: check according to related standards.
12. warehouse-ins: product is through putting in storage after the assay was approved.
Embodiment 3:
1. prepare according to the following steps Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT:
(1) preparation of Fructus lycii P.E: the fruit of Chinese wolfberry being cleaned and dried, pulverize, cross 50~60 mesh sieves, is 40kHz in supersonic frequency, power is 200w, and temperature is 60 ℃, and 70% the ethanol of take is to extract solvent, solid-liquid ratio is 1:20, ultrasonic extraction 30min, and then centrifugal concentrating is dried to obtain LBP-X;
(2) preparation of tuckahoe extracts: Poria cocos being cleaned and dried, pulverize, cross 20~60 mesh sieves, is 40kHz in supersonic frequency, power is 320w, and 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:10, temperature is 25 ℃, ultrasonic extraction 20min, and then centrifugal concentrating is dried to obtain pachymaran;
(3) preparation of GINKGO BILOBA EXTRACT: ginkgo leaf is cleaned and dried, pulverize, crossing 50~60 mesh sieves, is 40kHz in supersonic frequency, and power is 320w, temperature is 30 ℃, 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:15, ultrasonic extraction 10min, repeat to extract twice, then centrifugal concentrating is dried to obtain GINKGO BILOBA EXTRACT.
2. by following requirement check Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT, qualified is standby;
Each composition of Fructus lycii P.E requires:
LBP-X >=30.0%, moisture≤5.0%, ash content≤5.0%, heavy metal≤10mg/kg, arsenic (in As)≤1.0mg/kg, plumbous (in Pb)≤2.0mg/kg;
Each composition of tuckahoe extracts requires:
Pachymaran >=20.0%, moisture≤8.0%, ash content≤6.0%, arsenic (in As)≤0.5mg/kg, plumbous (in Pb)≤1.0mg/kg, copper (in Au)≤10.0mg/kg, sulfur dioxide residual quantity≤150mg/kg;
Each composition of ginkgo biloba extract requires:
GINKGO BILOBA EXTRACT >=24.0%, moisture≤5.0%, heavy metal≤10mg/kg, arsenic (in As)≤1.0mg/kg, residue on ignition≤0.8%.
3. extract Fructus lycii P.E 50g, tuckahoe extracts 50g, GINKGO BILOBA EXTRACT 30g, in 300,000 grades of clean areas, drops in V-type blender, mixes 35min, guarantees evenly.
4. in 300,000 grades of clean areas, take 5% polyvinylpyrrolidone (PVPK30) as wetting agent softwood processed, cross 28 mesh sieve wet granular processed.
5. in 300,000 grades of clean areas, wet granular is in 70 ℃ of heated-air dryings.
6. in 300,000 grades of clean areas, dry particle is crossed the whole grain of 22 mesh sieves.
7. capsule is filling: in 300,000 grades of clean areas, with capsule filler filling capsule, every capsules content 0.35g, should note monitoring product content uniformity during filling, is controlled in disparity range.
8. capsule polishing: in 300,000 grades of clean areas, remove the fine powder that sticks to capsule surface with polishing machine, sieve removes defective work simultaneously.
9. inner packing: in 300,000 grades of clean areas, inner packing adopts the oral stable medicinal polythene bottle with high density packing that meets YBB00122002 standard-required, 60 every bottle.
10. external packing: middle package paper box, 1 bottle, every box, large packing adopts corrugated case.
11. checks: check according to related standards.
12. warehouse-ins: product is through putting in storage after the assay was approved.

Claims (6)

1. the health food that can improve immunity, it is characterized in that its formula components is for (weight portion): Fructus lycii P.E: 30~50 parts, tuckahoe extracts: 30~50 parts, GINKGO BILOBA EXTRACT: 10~30 parts, the significant composition of described Fructus lycii P.E is LBP-X, the content of this LBP-X is not less than 30.0%, and component is in detail:
LBP-X >=30.0%;
Moisture≤5.0%;
Ash content≤5.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤1.0mg/kg;
Plumbous (in Pb)≤2.0mg/kg;
The significant composition of described tuckahoe extracts is pachymaran, and the content of this pachymaran is not less than 20.0%, and component is in detail:
Pachymaran >=20.0%;
Moisture≤8.0%;
Ash content≤6.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤0.5mg/kg;
Plumbous (in Pb)≤1.0mg/kg;
Copper (in Au)≤10.0mg/kg;
Sulfur dioxide residual quantity≤150mg/kg;
Described GINKGO BILOBA EXTRACT is ginkgo biloba p.e, and the content of this GINKGO BILOBA EXTRACT is not less than 24.0%, and component is in detail:
GINKGO BILOBA EXTRACT >=24.0%;
Moisture≤5.0%;
Heavy metal≤10mg/kg;
Arsenic (in As)≤1.0mg/kg;
Residue on ignition≤0.8%.
2. the health food that can improve immunity according to claim 1, is characterized in that its formula components is for (weight portion): Fructus lycii P.E: 40 parts, and tuckahoe extracts: 40 parts, GINKGO BILOBA EXTRACT: 20 parts.
3. the health food that can improve immunity according to claim 1, is characterized in that this health food to make capsule.
4. can improve health food and the raw material disposal method thereof of immunoregulation capability, it is characterized in that its technique comprises the following steps:
(1) preparation of Fructus lycii P.E: the fruit of Chinese wolfberry being cleaned and dried, pulverize, cross 50~60 mesh sieves, is 40kHz in supersonic frequency, power is 200w, and temperature is 60 ℃, and 70% the ethanol of take is to extract solvent, solid-liquid ratio is 1:20, ultrasonic extraction 30min, and then centrifugal concentrating is dried to obtain LBP-X;
(2) preparation of tuckahoe extracts: Poria cocos being cleaned and dried, pulverize, cross 20~60 mesh sieves, is 40kHz in supersonic frequency, power is 320w, and 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:10, temperature is 25 ℃, ultrasonic extraction 20min, and then centrifugal concentrating is dried to obtain pachymaran;
(3) preparation of GINKGO BILOBA EXTRACT: ginkgo leaf is cleaned and dried, pulverize, crossing 50~60 mesh sieves, is 40kHz in supersonic frequency, and power is 320w, temperature is 30 ℃, 70% the ethanol of take is to extract solvent, and solid-liquid ratio is 1:15, ultrasonic extraction 10min, repeat to extract twice, then centrifugal concentrating is dried to obtain GINKGO BILOBA EXTRACT.
5. one kind can be improved health food of immunity and preparation method thereof, it is characterized in that its technique comprises the following steps:
(1) by Fructus lycii P.E claimed in claim 1, tuckahoe extracts, GINKGO BILOBA EXTRACT, will check in accordance with regulations, qualified Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT are standby;
(2) mixing of materials:, drop in blender after Fructus lycii P.E, tuckahoe extracts, GINKGO BILOBA EXTRACT batching by the proportioning described in claim 1, mix 25~35min;
(3) granulate: with wetting agent softwood processed, cross 20~28 mesh sieve wet granular processed;
(4) dry: wet granular is in 50 ℃~70 ℃ heated-air dryings;
(5) whole grain: dry particle is crossed the whole grain of 18~22 mesh sieves;
(6) manufactured goods: filling capsule, every dose of content 0.25~0.35g;
(7) packing warehouse-in.
6. according to claim 5ly can improve health food of immunity and preparation method thereof, it is characterized in that described wetting agent is 5% polyvinylpyrrolidone PVPK30 ethanolic solution.
CN201410366957.8A 2014-07-30 2014-07-30 Health food capable of enhancing immunity and preparation method thereof Pending CN104187617A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410366957.8A CN104187617A (en) 2014-07-30 2014-07-30 Health food capable of enhancing immunity and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410366957.8A CN104187617A (en) 2014-07-30 2014-07-30 Health food capable of enhancing immunity and preparation method thereof

Publications (1)

Publication Number Publication Date
CN104187617A true CN104187617A (en) 2014-12-10

Family

ID=52073132

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410366957.8A Pending CN104187617A (en) 2014-07-30 2014-07-30 Health food capable of enhancing immunity and preparation method thereof

Country Status (1)

Country Link
CN (1) CN104187617A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107467666A (en) * 2017-09-19 2017-12-15 房洪全 It is a kind of to improve health food of immunity and preparation method thereof

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1475168A (en) * 2003-07-09 2004-02-18 大连鸿宇药业有限公司 Health food capable of raisiong organism immune power and its preparation method
CN101703623A (en) * 2009-11-12 2010-05-12 西安斯强实业有限公司 Capsule with effect of relieving physical fatigue
CN101817749A (en) * 2009-11-18 2010-09-01 青海青美生物资源研究开发有限公司 Method for extracting chlorogenic acid from Chinese wolfberry
CN102813199A (en) * 2012-09-03 2012-12-12 山东森健生物科技发展有限公司 Health-care food for prevention and adjuvant therapy of cancer, three-high disease and immunity strengthening
CN103005447A (en) * 2013-01-08 2013-04-03 湖南麓山天然植物制药有限公司 Health-care food composition with function of improving immunity and preparation method of composition
CN103156194A (en) * 2013-04-03 2013-06-19 上海春芝堂生物制品有限公司 Medlar and tuckahoe capsules and preparation method thereof
CN103250827A (en) * 2013-06-05 2013-08-21 楊光雲 Alcoholism prevention and liver protection pu'er tea powder and preparation technology thereof
CN103734712A (en) * 2013-12-02 2014-04-23 中国农业大学 Eye-protecting blueberry-raspberry functional food
CN103766885A (en) * 2012-10-26 2014-05-07 苏州市洋海电子有限公司 Health food for alleviating physical fatigue

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1475168A (en) * 2003-07-09 2004-02-18 大连鸿宇药业有限公司 Health food capable of raisiong organism immune power and its preparation method
CN101703623A (en) * 2009-11-12 2010-05-12 西安斯强实业有限公司 Capsule with effect of relieving physical fatigue
CN101817749A (en) * 2009-11-18 2010-09-01 青海青美生物资源研究开发有限公司 Method for extracting chlorogenic acid from Chinese wolfberry
CN102813199A (en) * 2012-09-03 2012-12-12 山东森健生物科技发展有限公司 Health-care food for prevention and adjuvant therapy of cancer, three-high disease and immunity strengthening
CN103766885A (en) * 2012-10-26 2014-05-07 苏州市洋海电子有限公司 Health food for alleviating physical fatigue
CN103005447A (en) * 2013-01-08 2013-04-03 湖南麓山天然植物制药有限公司 Health-care food composition with function of improving immunity and preparation method of composition
CN103156194A (en) * 2013-04-03 2013-06-19 上海春芝堂生物制品有限公司 Medlar and tuckahoe capsules and preparation method thereof
CN103250827A (en) * 2013-06-05 2013-08-21 楊光雲 Alcoholism prevention and liver protection pu'er tea powder and preparation technology thereof
CN103734712A (en) * 2013-12-02 2014-04-23 中国农业大学 Eye-protecting blueberry-raspberry functional food

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107467666A (en) * 2017-09-19 2017-12-15 房洪全 It is a kind of to improve health food of immunity and preparation method thereof

Similar Documents

Publication Publication Date Title
CN101297704B (en) Health care food for protecting liver and manufacturing method thereof
KR20130056780A (en) Cosmetic composition comprising soapnut
KR20160006427A (en) The health functional food for children comprising herbal plant treated by traditional processing
CN104187617A (en) Health food capable of enhancing immunity and preparation method thereof
CN108066384A (en) A kind of Chinese medicine preparation with strengthen immunity and preparation method thereof
CN103893223B (en) A kind of method of machining at low temperature Ganoderma
CN101342275B (en) Medicament for preventing and controlling aspergillus disease of chicken
CN107223966B (en) Roxburgh rose and licorice oral liquid for improving immunity and preparation method thereof
CN103142766B (en) Medicine for controlling coccidiosis in rabbits
CN105412472A (en) Traditional Chinese medicine composition for maintaining beauty and keeping young, building body and prolonging life
CN107467666A (en) It is a kind of to improve health food of immunity and preparation method thereof
CN109999058A (en) A kind of molten method of glue class Chinese medicine and product, and the solid beverage as made from the product and preparation method thereof
CN103783216A (en) Flammulina velutipes barley tea drink and fabrication method thereof
CN104095238A (en) Health food capable of improving immune adjustment capacity and preparation method thereof
KR20070107393A (en) Composition for promotion of growth
CN105231325A (en) Mauremys mutica, chelydra serpentina, radix codonopsis, and astragalus membranaceus powder and preparation method thereof
CN105685912A (en) Lung-moistening cough-relieving honey containing citrus honey and lily honey
CN105920053A (en) Preparation method of phellinus igniarius fine powder
CN106138341A (en) Leaf of Moringa compounding powder, production method and purposes
CN106038988B (en) It is a kind of for preventing and treating the natural plant extracts and its preparation of pneumoconiosis
CN103583790A (en) Processing method of marine biological calcium protein powder
Chithra et al. Evaluvation of the Lactogenic activity of Erythrina indica Lam. leaves
CN102048962A (en) Gastrodia tuber oral liquid and preparation method thereof
CN109223973B (en) Radiation-proof composition and preparation method and application thereof
CN110090267A (en) A kind of preparation method of the Chinese medicine dry powder doses with Antiageing effect

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20141210

WD01 Invention patent application deemed withdrawn after publication