CN1520300B - 用于治疗病毒感染、心血管病、炎症、超敏反应或疼痛的二氢三萜烯 - Google Patents

用于治疗病毒感染、心血管病、炎症、超敏反应或疼痛的二氢三萜烯 Download PDF

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Publication number
CN1520300B
CN1520300B CN028036794A CN02803679A CN1520300B CN 1520300 B CN1520300 B CN 1520300B CN 028036794 A CN028036794 A CN 028036794A CN 02803679 A CN02803679 A CN 02803679A CN 1520300 B CN1520300 B CN 1520300B
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alcohol
composition
triterpenes
triterpene
present
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CN028036794A
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CN1520300A (zh
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莫滕·斯洛斯·韦德纳
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BSP Pharma AS
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BSP Pharma AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Epidemiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Birds (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN028036794A 2001-01-12 2002-01-14 用于治疗病毒感染、心血管病、炎症、超敏反应或疼痛的二氢三萜烯 Expired - Fee Related CN1520300B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200100049 2001-01-12
DKPA200100049 2001-01-12
US26116801P 2001-01-16 2001-01-16
US60/261,168 2001-01-16
PCT/IB2002/000081 WO2002055087A1 (en) 2001-01-12 2002-01-14 Dihydro-triterpenes in the treatment of viral infections, cardiovascular disease, inflammation, hypersensitivity or pain

Publications (2)

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CN1520300A CN1520300A (zh) 2004-08-11
CN1520300B true CN1520300B (zh) 2010-10-06

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CN028036794A Expired - Fee Related CN1520300B (zh) 2001-01-12 2002-01-14 用于治疗病毒感染、心血管病、炎症、超敏反应或疼痛的二氢三萜烯

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EP (1) EP1349553B1 (enExample)
JP (1) JP2004520343A (enExample)
CN (1) CN1520300B (enExample)
AT (1) ATE338556T1 (enExample)
AU (1) AU2002225259B2 (enExample)
CA (1) CA2434670C (enExample)
CY (1) CY1106270T1 (enExample)
DE (1) DE60214509T2 (enExample)
DK (1) DK1349553T3 (enExample)
ES (1) ES2272689T3 (enExample)
NZ (1) NZ526969A (enExample)
WO (1) WO2002055087A1 (enExample)

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
US7070815B2 (en) 2002-11-27 2006-07-04 Loders Croklaan Usa Llc Anti diarrhoea compositions
EP1424073A1 (en) * 2002-11-27 2004-06-02 Loders Croklaan B.V. Anti diarrhoea compositions
US20060003948A1 (en) * 2004-02-06 2006-01-05 Krasutsky Pavel A Compositions that include a triterpene and a carrier
JP4810642B2 (ja) * 2004-11-30 2011-11-09 秋田県 癌転移抑制用トリテルペン誘導体及び該トリテルペン誘導体を用いた癌転移抑制用組成物
JPWO2007108042A1 (ja) * 2006-03-15 2009-07-30 株式会社トロピカルテクノセンター 抗炎症剤
JP5428000B2 (ja) * 2007-06-27 2014-02-26 株式会社スカイライト・バイオテック ルペオール含有医薬組成物、食品及び飼料
CN102499925B (zh) * 2011-10-21 2015-11-11 上海中医药大学 一种中性粒细胞弹性蛋白酶抑制剂
CN104107179B (zh) * 2014-06-27 2016-08-24 王英 闭花木酮Cleistanone的二乙胺衍生物在制备抗急性痛风药物中的应用
KR101672431B1 (ko) * 2015-01-06 2016-11-04 목포대학교산학협력단 동백나무 추출물을 유효성분으로 포함하는 심혈관계 질환의 예방 또는 치료용 조성물
CN106265684A (zh) * 2016-08-11 2017-01-04 江苏康缘药业股份有限公司 乙酰羽扇豆醇酯的应用
IT201600093764A1 (it) * 2016-09-19 2018-03-19 Codex V Srl Insaponificabili di lipidi naturali per l’uso nel trattamento di patologie reumatiche
WO2018082034A1 (en) * 2016-11-04 2018-05-11 Trineo Biotechnology Co., Ltd Uses of triterpenoid mixture for treating multiple sclerosis
CN113993533A (zh) * 2019-05-22 2022-01-28 人类科学有限公司 包含山茶树提取物作为有效成分的用于预防及治疗病毒感染的药物组合物

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GB932662A (en) * 1960-04-13 1963-07-31 Laroche Navarron Lab Therapeutic compositions comprising butyrospermol

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CA1265785A (en) * 1984-06-04 1990-02-13 Kumi Yoshida Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them
JP2912489B2 (ja) * 1992-01-10 1999-06-28 サンスター株式会社 皮膚化粧料
CA2193396A1 (en) * 1994-06-20 1995-12-28 Kurt Berg A pharmaceutical composition for the prevention and/or treatment of viral infections and optionally inflammations as well as a method for the treatment thereof
WO1998032443A1 (de) * 1997-01-24 1998-07-30 Marigen S.A. Ultramikroemulsionen aus spontan dispergierbaren konzentraten enthaltend antitumoral, antiviral und antiparasitär wirksame ester von pentacyclischen triterpenen
FR2770400B1 (fr) * 1997-10-30 1999-12-03 Sederma Sa Compositions a usage cosmetique ou dermopharmaceutique contenant un extrait vegetal obtenu a partir de la fleur de l'arbre a karite ou butyrospermum parkii kotschy
JP2003504340A (ja) * 1999-07-09 2003-02-04 ベーエスペー ファルマ アクティーゼルスカブ ブチロスペルマムパルキイの抽出物を含有する組成物および薬剤または栄養補助食品としての使用

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GB932662A (en) * 1960-04-13 1963-07-31 Laroche Navarron Lab Therapeutic compositions comprising butyrospermol

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TOSHIHIRO ITOH等.Sterols, methyl sterols, and triterpene alcohols in threeTHEACEAE and some other vegetable oils.LIPIDS9 3.1974,9(3),173-784. *

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DE60214509D1 (de) 2006-10-19
EP1349553B1 (en) 2006-09-06
CY1106270T1 (el) 2011-10-12
WO2002055087A1 (en) 2002-07-18
DE60214509T2 (de) 2007-05-31
EP1349553A1 (en) 2003-10-08
JP2004520343A (ja) 2004-07-08
NZ526969A (en) 2005-05-27
WO2002055087B1 (en) 2002-12-27
CA2434670A1 (en) 2002-07-18
ES2272689T3 (es) 2007-05-01
DK1349553T3 (da) 2007-01-08
AU2002225259B2 (en) 2006-02-02
ATE338556T1 (de) 2006-09-15
CN1520300A (zh) 2004-08-11
CA2434670C (en) 2010-05-11

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