CY1106270T1 - Διυδρο-τριτepπενια στην αντιμετωπιση ιογενων μολυνσεων, καρδιαγγειακης νοσου, φλεγμονης, υπepευαισθησιας ή πονου - Google Patents
Διυδρο-τριτepπενια στην αντιμετωπιση ιογενων μολυνσεων, καρδιαγγειακης νοσου, φλεγμονης, υπepευαισθησιας ή πονουInfo
- Publication number
- CY1106270T1 CY1106270T1 CY20061101714T CY061101714T CY1106270T1 CY 1106270 T1 CY1106270 T1 CY 1106270T1 CY 20061101714 T CY20061101714 T CY 20061101714T CY 061101714 T CY061101714 T CY 061101714T CY 1106270 T1 CY1106270 T1 CY 1106270T1
- Authority
- CY
- Cyprus
- Prior art keywords
- infections
- triteppenia
- generous
- dihydro
- inflammation
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title abstract 2
- 230000004054 inflammatory process Effects 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000035945 sensitivity Effects 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 150000003648 triterpenes Chemical class 0.000 abstract 3
- 239000002537 cosmetic Substances 0.000 abstract 2
- 235000015872 dietary supplement Nutrition 0.000 abstract 2
- XHMHQMBOUUDXGO-FXCPCPCLSA-N (3S,5R,8S,10S,13R,14S,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,5,6,7,8,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol Chemical compound CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@]4(C)[C@@H]3CC[C@H]21 XHMHQMBOUUDXGO-FXCPCPCLSA-N 0.000 abstract 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 abstract 1
- UBLNLUPLUKPSPP-UHFFFAOYSA-N 3-beta-form-3-Lupanol Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C)CCC(C(C)C)C5C4CCC3C21C UBLNLUPLUKPSPP-UHFFFAOYSA-N 0.000 abstract 1
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 235000011054 acetic acid Nutrition 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229930016911 cinnamic acid Natural products 0.000 abstract 1
- 235000013985 cinnamic acid Nutrition 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
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- Biotechnology (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με συνθέσεις οι οποίες περιλαμβάνουν τα τριτερπένια, διυδροβουτυροσπερμόλη, διυδρολουπεόλη και/ή διυδροπαρκεόλη, με τη σύνθεση να μπορεί να εφαρμοστεί ως ένα φαρμακευτικό σκεύασμα, ένα διαιτητικό συμπλήρωμα ή ως ένα καλλυντικό. Περαιτέρω, η εφεύρεση σχετίζεται με τη χρήση αυτών των συνθέσεων για την παρασκευή ενός φαρμάκου, ενός διαιτητικού συμπληρώματος ή ενός καλλυντικού για ανοσοδιαμόρφωση σε ένα θηλαστικό όπως καταστολή ιογενών μολύνσεων, καρδιαγγειακών νόσων, καρκίνου, υπερευαισθησίας και/ή φλεγμονωδών αντιδράσεων. Τα τριτερπένια μπορεί να είναι στη μορφή της ελεύθερης αλκοόλης ή παραγωγοποιημένα, κατά προτίμηση με κινναμικό οξύ, οξικό οξύ ή λιπαρά οξέα. Περαιτέρω, τα τριτερπένια μπορεί να είναι ένα εκχύλισμα το οποίο μπορεί να ληφθεί από μια φυσική πηγή ή να φτιαχτεί συνθετικά.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200100049 | 2001-01-12 | ||
| US26116801P | 2001-01-16 | 2001-01-16 | |
| PCT/IB2002/000081 WO2002055087A1 (en) | 2001-01-12 | 2002-01-14 | Dihydro-triterpenes in the treatment of viral infections, cardiovascular disease, inflammation, hypersensitivity or pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1106270T1 true CY1106270T1 (el) | 2011-10-12 |
Family
ID=26068943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20061101714T CY1106270T1 (el) | 2001-01-12 | 2006-11-28 | Διυδρο-τριτepπενια στην αντιμετωπιση ιογενων μολυνσεων, καρδιαγγειακης νοσου, φλεγμονης, υπepευαισθησιας ή πονου |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1349553B1 (el) |
| JP (1) | JP2004520343A (el) |
| CN (1) | CN1520300B (el) |
| AT (1) | ATE338556T1 (el) |
| AU (1) | AU2002225259B2 (el) |
| CA (1) | CA2434670C (el) |
| CY (1) | CY1106270T1 (el) |
| DE (1) | DE60214509T2 (el) |
| DK (1) | DK1349553T3 (el) |
| ES (1) | ES2272689T3 (el) |
| NZ (1) | NZ526969A (el) |
| WO (1) | WO2002055087A1 (el) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7070815B2 (en) | 2002-11-27 | 2006-07-04 | Loders Croklaan Usa Llc | Anti diarrhoea compositions |
| EP1424073A1 (en) * | 2002-11-27 | 2004-06-02 | Loders Croklaan B.V. | Anti diarrhoea compositions |
| US20060003948A1 (en) * | 2004-02-06 | 2006-01-05 | Krasutsky Pavel A | Compositions that include a triterpene and a carrier |
| JP4810642B2 (ja) * | 2004-11-30 | 2011-11-09 | 秋田県 | 癌転移抑制用トリテルペン誘導体及び該トリテルペン誘導体を用いた癌転移抑制用組成物 |
| US20100055219A1 (en) * | 2006-03-15 | 2010-03-04 | Tropical Technology Center Ltd. | Antiinflammatory agent |
| JP5428000B2 (ja) * | 2007-06-27 | 2014-02-26 | 株式会社スカイライト・バイオテック | ルペオール含有医薬組成物、食品及び飼料 |
| CN102499925B (zh) * | 2011-10-21 | 2015-11-11 | 上海中医药大学 | 一种中性粒细胞弹性蛋白酶抑制剂 |
| CN104107179B (zh) * | 2014-06-27 | 2016-08-24 | 王英 | 闭花木酮Cleistanone的二乙胺衍生物在制备抗急性痛风药物中的应用 |
| KR101672431B1 (ko) * | 2015-01-06 | 2016-11-04 | 목포대학교산학협력단 | 동백나무 추출물을 유효성분으로 포함하는 심혈관계 질환의 예방 또는 치료용 조성물 |
| CN106265684A (zh) * | 2016-08-11 | 2017-01-04 | 江苏康缘药业股份有限公司 | 乙酰羽扇豆醇酯的应用 |
| IT201600093764A1 (it) * | 2016-09-19 | 2018-03-19 | Codex V Srl | Insaponificabili di lipidi naturali per l’uso nel trattamento di patologie reumatiche |
| WO2018082034A1 (en) * | 2016-11-04 | 2018-05-11 | Trineo Biotechnology Co., Ltd | Uses of triterpenoid mixture for treating multiple sclerosis |
| CN113993533A (zh) * | 2019-05-22 | 2022-01-28 | 人类科学有限公司 | 包含山茶树提取物作为有效成分的用于预防及治疗病毒感染的药物组合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB932662A (en) * | 1960-04-13 | 1963-07-31 | Laroche Navarron Lab | Therapeutic compositions comprising butyrospermol |
| CA1265785A (en) * | 1984-06-04 | 1990-02-13 | Kumi Yoshida | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them |
| JP2912489B2 (ja) * | 1992-01-10 | 1999-06-28 | サンスター株式会社 | 皮膚化粧料 |
| AU689603B2 (en) * | 1994-06-20 | 1998-04-02 | Kurt Berg | A pharmaceutical composition for the prevention and/or treatment of viral infections and optionally inflammations as well as a method for the treatment thereof |
| EP0902685A1 (de) * | 1997-01-24 | 1999-03-24 | Marigen S.A. | Ultramikroemulsionen aus spontan dispergierbaren konzentraten enthaltend antitumoral, antiviral und antiparasitär wirksame ester von pentacyclischen triterpenen |
| FR2770400B1 (fr) * | 1997-10-30 | 1999-12-03 | Sederma Sa | Compositions a usage cosmetique ou dermopharmaceutique contenant un extrait vegetal obtenu a partir de la fleur de l'arbre a karite ou butyrospermum parkii kotschy |
| CA2378396C (en) * | 1999-07-09 | 2010-12-21 | Bsp Pharma A/S | Composition containing extracts of butyrospermum parkii and the use as medicament or dietary supplement |
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2002
- 2002-01-14 NZ NZ526969A patent/NZ526969A/en not_active IP Right Cessation
- 2002-01-14 CA CA2434670A patent/CA2434670C/en not_active Expired - Fee Related
- 2002-01-14 AT AT02715601T patent/ATE338556T1/de active
- 2002-01-14 DK DK02715601T patent/DK1349553T3/da active
- 2002-01-14 JP JP2002555821A patent/JP2004520343A/ja active Pending
- 2002-01-14 DE DE60214509T patent/DE60214509T2/de not_active Expired - Lifetime
- 2002-01-14 AU AU2002225259A patent/AU2002225259B2/en not_active Ceased
- 2002-01-14 ES ES02715601T patent/ES2272689T3/es not_active Expired - Lifetime
- 2002-01-14 CN CN028036794A patent/CN1520300B/zh not_active Expired - Fee Related
- 2002-01-14 WO PCT/IB2002/000081 patent/WO2002055087A1/en active IP Right Grant
- 2002-01-14 EP EP02715601A patent/EP1349553B1/en not_active Expired - Lifetime
-
2006
- 2006-11-28 CY CY20061101714T patent/CY1106270T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2434670C (en) | 2010-05-11 |
| AU2002225259B2 (en) | 2006-02-02 |
| ES2272689T3 (es) | 2007-05-01 |
| EP1349553B1 (en) | 2006-09-06 |
| EP1349553A1 (en) | 2003-10-08 |
| CN1520300A (zh) | 2004-08-11 |
| DE60214509D1 (de) | 2006-10-19 |
| JP2004520343A (ja) | 2004-07-08 |
| NZ526969A (en) | 2005-05-27 |
| CA2434670A1 (en) | 2002-07-18 |
| WO2002055087B1 (en) | 2002-12-27 |
| CN1520300B (zh) | 2010-10-06 |
| ATE338556T1 (de) | 2006-09-15 |
| WO2002055087A1 (en) | 2002-07-18 |
| DK1349553T3 (da) | 2007-01-08 |
| DE60214509T2 (de) | 2007-05-31 |
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