CN1480044A - High performance iodine disinfection liquid - Google Patents
High performance iodine disinfection liquid Download PDFInfo
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- CN1480044A CN1480044A CNA031338550A CN03133855A CN1480044A CN 1480044 A CN1480044 A CN 1480044A CN A031338550 A CNA031338550 A CN A031338550A CN 03133855 A CN03133855 A CN 03133855A CN 1480044 A CN1480044 A CN 1480044A
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- iodine
- water
- boric acid
- glycerine
- potassium iodide
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Abstract
An efficient disinfecting liquid "tamed iodine" for medical purpose is prepared from iodine, potassium iodie, potassium iodate, glycerine, boric acid, polyvinyloxyether and water through dissolving potassium iodide and potassium iodate in water, sequentially adding others while stirring, colloid gringing, adding water, and stirring. Its advantages are high disinfecting power and safety, and less volatilization and deposition of iodine.
Description
Technical field: the present invention relates to be used in the medical medicine industry a kind of broad-spectrum disinfectant that skin degerming is handled and instrument soaking is disinfected.
Background technology: at present, the medicine that is used for the external application Iodophor class of sterilization mainly contains polyvinylpyrrolidone-I liquid (PVP-I), polyethylene glycol-I (PEG-I) etc., is mainly used in skin degerming.Tincture of iodine bactericidal action is strong, the content of its iodine is 2%, the content of potassium iodide is 1.5%, because of the strong impulse effect is arranged, should not be used to the film of sterilizing, when being used for skin degerming, treat that the tincture of iodine is done after, must remove with wipes of alcohol, otherwise can cause skin foaming or irritated, also skin be had painted simultaneously.Above-mentioned Iodophor does not dye little with the excitant of mucous membrane to skin than the tincture of iodine, but because of its less stable, easily produce the volatilization of precipitation and iodine, and the content reduced rate of iodine is higher in the soup term of validity.Therefore develop a kind of efficient disinfectant tamed iodine is new problem anxious to be solved in the domestic and international medical domain always.
Summary of the invention: the object of the present invention is achieved like this, this liquid is formulated by the mixed grinding of iodine, potassium iodide, Potassiumiodate, glycerine, boric acid, APEO and water, wherein prepare in the 100kg thimerosal, each components contents is respectively that iodine is that 0.25-1kg, potassium iodide are 0.1-0.5kg, Potassiumiodate 0.1-0.4kg, glycerine 1-4kg, boric acid 0.2kg, APEO 5-15kg, water 80-90kg; Its preparation method is, at first get after potassium iodide, Potassiumiodate be dissolved in water, it is miscible in agitator tank to add iodine, again boric acid, glycerine, APEO are mixed, add the suitable quantity of water stirring and evenly mixing then, insert in the colloid mill with above-mentioned solution again and grind, after injecting container at last and adding water and stir, the holding vessel of packing into,, can qualified, packing warehouse-in through chemically examining.Main points of the present invention are its formula for a product, preparation technology and pharmacology.Pharmacology of the present invention is, because the present invention is the aqueous solution that forms chelated iodine with specific non-ionic surfactant polyoxyethylene ether and elemental iodine complexing, wherein add Potassiumiodate, potassium iodide and boric acid are as cosolvent, three's reduction reaction can produce iodine, be used for replenishing the loss of iodine in the chelated iodine storing process for a long time, prevent the volatilization of iodine, precipitation, the stability that therefore can keep this thimerosal, the availability that has also improved simultaneously elemental iodine improves the bactericidal action of thimerosal, so can effectiveness extremely lowly take place in concentration, significantly economize on survival dose and the minimizing stimulation to skin.The potassium iodide that contains in the aqueous solution, glycerine, iodine, boric acid; wherein iodine is main bactericide; glycerine can make soup stable; lubrication protection skin, potassium iodide can make element potassium fully dissolve with solution in, boric acid itself also has bactericidal action; this forms solution; self is disinfectant, so synergy is arranged, can increase the bactericidal amount of chelated iodine.Add boric acid to regulate pH value, make it to remain between the 3.5-6.0, reach solubilization, to improve drug effect.In addition, non-ionic surfactant polyoxyethylene ether is except that having washability, and it also has stronger affinity interaction to somatic cells, after carrier and cosolvent and iodine complexing, affinity to somatic cells strengthens, and contained iodine can be transported on the somatic cells film.And the target tissue majority of iodine is on cytoplasm or cell membrane, and iodine is once combining with target tissue, and promptly permeates cell membranes reaches the mycoprotein deep, i.e. sterilization.For this reason, the Synergistic biocidal effect has been played in APEO and iodine complexing, has effectively improved the Disinfection Effect of iodine, increases the solvability of iodine, reduces the concentration and the excitant of iodine.Through practical application and testing identity, non-stimulated, not irritated, not painted, have washability when this liquid is used for skin degerming, result of treatment is remarkable, no side effects.A kind of efficient disinfectant tamed iodine compared with prior art, have that preparation technology is simple, the soup stable performance, consume less, sterilizing ability is strong, fungicidal effectiveness is lasting, can effectively prevent volatilization, the precipitation of iodine, do not stimulate during to skin degerming, not irritated, not painted, has washability, result of treatment is remarkable, and advantages such as no side effects will be widely used in the medical medicine industry.
Embodiment:
Embodiment one, after at first getting potassium iodide 0.5kg, Potassiumiodate 0.4kg and being dissolved in water, it is miscible in agitator tank to add iodine 0.5kg, again boric acid 0.2kg, glycerine 2kg, APEO 9.8kg are mixed, add the suitable quantity of water stirring and evenly mixing then, insert in the colloid mill with above-mentioned solution again and grind, after injecting container at last and adding water to 100kg and stir, the holding vessel of packing into,, can qualified, packing warehouse-in through chemically examining.
Embodiment two, after at first getting potassium iodide 0.3kg, Potassiumiodate 0.25kg and being dissolved in water, it is miscible in agitator tank to add iodine 0.25kg, again boric acid 0.2kg, glycerine 2.5kg, APEO 7.5kg are mixed, add the suitable quantity of water stirring and evenly mixing then, insert in the colloid mill with above-mentioned solution again and grind, after injecting container at last and adding water to 100kg and stir, the holding vessel of packing into,, can qualified, packing warehouse-in through chemically examining.
Claims (2)
1, a kind of efficient disinfectant tamed iodine, mixed grinding by iodine, potassium iodide, Potassiumiodate, glycerine, boric acid, APEO and water is formulated, it is characterized in that: wherein prepare in the 100kg thimerosal, each components contents is respectively that iodine is that 0.25-1kg, potassium iodide are 0.1-0.5kg, Potassiumiodate 0.1-0.4kg, glycerine 1-4kg, boric acid 0.2kg, APEO 5-15kg, water 80-90kg.
2, a kind of efficient disinfectant tamed iodine according to claim 1, it is characterized in that: its product preparation process is, at first get after potassium iodide, Potassiumiodate be dissolved in water, it is miscible in agitator tank to add iodine, boric acid, glycerine, APEO is mixed again, and adds the suitable quantity of water stirring and evenly mixing then, insert in the colloid mill with above-mentioned solution again and grind, after injecting container at last and adding water and stir, the holding vessel of packing into,, can qualified, packing warehouse-in through chemically examining.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031338550A CN1480044A (en) | 2003-07-04 | 2003-07-04 | High performance iodine disinfection liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA031338550A CN1480044A (en) | 2003-07-04 | 2003-07-04 | High performance iodine disinfection liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1480044A true CN1480044A (en) | 2004-03-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA031338550A Pending CN1480044A (en) | 2003-07-04 | 2003-07-04 | High performance iodine disinfection liquid |
Country Status (1)
| Country | Link |
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| CN (1) | CN1480044A (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103222476A (en) * | 2013-05-15 | 2013-07-31 | 上海宇昂新材料科技有限公司 | Iodic acid solution for aquaculture and preparation method thereof |
| CN103891773A (en) * | 2014-04-21 | 2014-07-02 | 成都科宏达科技有限公司 | Sterilizing agent and preparation method thereof |
| CN106342886A (en) * | 2016-08-30 | 2017-01-25 | 四川创美克科技有限公司 | Compound type active iodine disinfectant for livestock, preparing method and purpose thereof |
| CN107308184A (en) * | 2017-07-18 | 2017-11-03 | 江苏海尔滋生物科技有限公司 | Icodextrin biomaterial and preparation method thereof |
| CN108013072A (en) * | 2016-11-02 | 2018-05-11 | 定州市荣鼎水环境生化技术有限公司 | Efficient sterilization disinfectant and preparation method thereof |
| CN108721328A (en) * | 2018-06-09 | 2018-11-02 | 江苏海尔滋生物科技有限公司 | Chitosan iodine biomaterial and preparation method thereof |
| CN111035674A (en) * | 2020-03-06 | 2020-04-21 | 吉林云飞医药有限公司 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
| CN114053299A (en) * | 2020-08-03 | 2022-02-18 | 成都中光洗消剂有限公司 | Compound iodine disinfectant and preparation method thereof |
-
2003
- 2003-07-04 CN CNA031338550A patent/CN1480044A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103222476A (en) * | 2013-05-15 | 2013-07-31 | 上海宇昂新材料科技有限公司 | Iodic acid solution for aquaculture and preparation method thereof |
| CN103891773A (en) * | 2014-04-21 | 2014-07-02 | 成都科宏达科技有限公司 | Sterilizing agent and preparation method thereof |
| CN106342886A (en) * | 2016-08-30 | 2017-01-25 | 四川创美克科技有限公司 | Compound type active iodine disinfectant for livestock, preparing method and purpose thereof |
| CN108013072A (en) * | 2016-11-02 | 2018-05-11 | 定州市荣鼎水环境生化技术有限公司 | Efficient sterilization disinfectant and preparation method thereof |
| CN108013072B (en) * | 2016-11-02 | 2021-04-27 | 定州市荣鼎水环境生化技术有限公司 | High-efficiency sterilizing disinfectant and preparation method thereof |
| CN107308184A (en) * | 2017-07-18 | 2017-11-03 | 江苏海尔滋生物科技有限公司 | Icodextrin biomaterial and preparation method thereof |
| CN108721328A (en) * | 2018-06-09 | 2018-11-02 | 江苏海尔滋生物科技有限公司 | Chitosan iodine biomaterial and preparation method thereof |
| CN108721328B (en) * | 2018-06-09 | 2020-12-01 | 江苏海尔滋生物科技有限公司 | Chitosan iodine biological material and preparation method thereof |
| CN111035674A (en) * | 2020-03-06 | 2020-04-21 | 吉林云飞医药有限公司 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
| CN114053299A (en) * | 2020-08-03 | 2022-02-18 | 成都中光洗消剂有限公司 | Compound iodine disinfectant and preparation method thereof |
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