CN111035674A - Aner iodine skin mucosa disinfectant as well as preparation method and application thereof - Google Patents
Aner iodine skin mucosa disinfectant as well as preparation method and application thereof Download PDFInfo
- Publication number
- CN111035674A CN111035674A CN202010151118.XA CN202010151118A CN111035674A CN 111035674 A CN111035674 A CN 111035674A CN 202010151118 A CN202010151118 A CN 202010151118A CN 111035674 A CN111035674 A CN 111035674A
- Authority
- CN
- China
- Prior art keywords
- purity
- iodine
- percent
- disinfectant
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the technical field of skin mucosa disinfectant, and particularly relates to an iodine-containing skin mucosa disinfectant, and a preparation method and application thereof. The iodine skin mucosa disinfectant comprises the following components in parts by weight: iodine with purity of 99% 0.23%; 60.0% of ethanol with the purity of 95%; chlorhexidine acetate with purity of 99% 0.5%; potassium iodide 0.17% with purity of 99%, potassium iodate 0.15% with purity of 99%, peppermint oil 0.05% with purity of 50%, glycerol 3.0% with purity of 99%, and the balance of purified deionized water. The invention is an environment-friendly sterilization disinfectant, and has the characteristics of wide sterilization spectrum and high efficiency; the antibacterial agent can be used at normal temperature, has long antibacterial time and low toxicity, and is safe and effective; the paint has no corrosion to various materials; has the effects of disinfection, sterilization, skin moistening and water retention.
Description
Technical Field
The invention belongs to the technical field of skin mucosa disinfectant, and particularly relates to an iodine-containing skin mucosa disinfectant as well as a preparation method and application thereof.
Background
Skin mucosa disinfection is a common disinfection task in health care facilities. At present, the disinfection solution has various types, and mainly comprises oxidation, aldehydes, alcohols, heavy metal salts, halogens and surfactants according to the action mechanism, such as formaldehyde and glutaraldehyde which are frequently used as aldehydes, and benzalkonium bromide (benzalkonium bromide) which is a surfactant. However, the above mentioned common disinfectants have their own disadvantages, and oxidizing disinfectants such as peroxide disinfectants are unstable in chemical properties, and high concentration can cause irritation to skin and damage to mucous membrane; aldehyde disinfectant such as formaldehyde belongs to A carcinogens and is flammable and difficult to decompose; glutaraldehyde is irritant to skin mucosa and can cause damage to the mucosa; alcohol disinfectants such as ethanol are volatile, can be influenced by organic matters, and have slow onset time; heavy metal salt disinfectants have great pollution, and the low temperature and organic matters can reduce the disinfection effect; the chlorine-containing disinfectant in the halogen disinfectant is easily influenced by organic matters and pH value and has a bleaching effect; iodine-containing disinfectant is easy to yellow and volatile; surfactants such as benzalkonium bromide tend to remain and are ineffective against gram-negative bacteria and spores. The common disinfectant liquids have respective disadvantages, and the disinfection effect is not ideal.
In summary, the problems of the prior art are as follows: the common skin mucosa disinfectant has various types, but each type of common disinfectant has respective disadvantages and has an unsatisfactory use effect.
Currently, the closest prior art is the iodine aqua disinfectant. The main components of the anidine disinfectant are effective iodine, chlorhexidine acetate and ethanol, and belongs to a powerful, high-efficiency and broad-spectrum disinfectant for skin and mucosa. Because iodine has the characteristic of volatility, the concentration of effective iodine is gradually reduced along with the prolonging of time, the effective period is short, the effective period is one week after the bottle is opened, the longer the time is, the poorer the sterilization effect is, therefore, the commonly used anidine disinfectant is small package products, and the large package products are rare. Because the alcohol is contained and has certain irritation to the skin mucosa, the anidine disinfectant has the technical defects of short effective period, small packaging amount and large irritation to the skin mucosa.
In order to solve the technical defects of the iodine disinfectant, the volatile property of the iodine disinfectant can be reduced by adding other components and complexing or adsorbing free iodine, and meanwhile, under the condition that the concentration level of the free iodine is lower, the iodine is released, and the concentration level of the effective iodine is maintained, so that the effective period of the disinfectant is prolonged; the effective period is prolonged, the dosage of single package can be increased, and the risk of failure in a short time is not needed to be worried about after the package is opened; by compounding, the sterilizing capability of the disinfectant can be enhanced, the sterilization is more thorough and rapid, and the sterilization cannot be greatly influenced even if the free iodine is reduced; by adding other components, the touch feeling is cool, and irritation of ethanol to skin and mucous membrane is reduced.
Iodine is highly soluble in ethanol, but is poorly soluble in water. Potassium iodide can form potassium triiodide with iodine by adding the potassium iodide, wherein the potassium iodide can be used as a cosolvent to increase the solubility of iodine in water, bind free iodine and delay the volatilization of iodine; meanwhile, when the concentration level of free iodine is lower, the iodine is released, so that the effective iodine is in an effective level for a long time, and the purpose of prolonging the effective period is achieved; the existence of potassium iodate can make the whole body more stable, potassium iodide and potassium iodate are the stabilizer of the iodine disinfectant commonly used, improve the system stability; the stability is improved, the validity period is prolonged, the dosage of single package can be increased, and the risk of failure in a short time is not needed to be worried about after the package is opened; by adding chlorhexidine acetate, the overall sterilizing capability and sterilizing efficiency of the disinfectant can be greatly improved, and the disinfectant is more thorough and rapid to sterilize; by adding the peppermint oil and the glycerin, the functions of water retention and skin moistening are provided, the touch feeling is cool and comfortable, the local temperature of the part where the skin is smeared is reduced, and the irritation to the skin and mucous membranes is relieved.
The invention is an environment-friendly sterilization disinfectant, has extremely strong capability of killing bacteria, and has the characteristics of wide sterilization spectrum and high efficiency; the antibacterial agent can be used at normal temperature, has long antibacterial time, no side effect, low toxicity, safety and effectiveness; the paint has no corrosion to various materials; no harmful substances such as chlorine, aldehyde and the like; has effects of sterilizing, moistening skin, keeping water, refreshing and comfortable touch feeling, and reducing irritation to skin and mucous membrane.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides an iodine-containing skin mucosa disinfectant as well as a preparation method and application thereof.
The invention is realized in such a way that the Aner iodine skin mucosa disinfectant consists of, by weight, 0.23% of iodine with the purity of 99%, 60% of ethanol with the purity of 95%, 0.5% of chlorhexidine acetate with the purity of 99%, 0.17% of potassium iodide with the purity of 99%, 0.15% of potassium iodate with the purity of 99%, 0.05% of peppermint oil with the purity of 50%, 3.0% of glycerol with the purity of 99%, and the balance of deionized water, wherein the deionized water is supplemented to 100%.
Furthermore, every 1000Kg of the prescription of the iodine-containing skin mucosa disinfectant comprises 2.3 Kg of iodine with the purity of 99 percent, 600 Kg of ethanol with the purity of 95 percent, 5Kg of chlorhexidine acetate with the purity of 99 percent, 1.7Kg of potassium iodide with the purity of 99 percent, 1.5Kg of potassium iodate with the purity of 99 percent, 0.5Kg of peppermint oil with the purity of 50 percent, 30Kg of glycerol with the purity of 99 percent, and the balance of purified deionized water which is added to the prescription to be 1000 Kg.
Another object of the present invention is to provide a method for preparing an iodine-containing disinfectant for skin and mucosa, the method comprising the steps of:
preparing raw materials in parts by weight: iodine with the purity of 99 percent 0.23 percent, ethanol with the purity of 95 percent 60 percent, chlorhexidine acetate with the purity of 99 percent 0.5 percent, potassium iodide with the purity of 99 percent 0.17 percent, potassium iodate with the purity of 99 percent 0.15 percent, peppermint oil with the purity of 50 percent 0.05 percent, glycerol with the purity of 99 percent 3.0 percent, and the balance of purified deionized water;
dissolving potassium iodide, potassium iodate, iodine, chlorhexidine acetate, peppermint oil and glycerol into an ethanol solution, and stirring to obtain a homogeneous solution;
adding purified ionic water to full volume, and performing constant volume and aging;
step four, inspecting the obtained intermediate product;
step five, if the product is qualified, filling and sealing the product by using disinfectant plastic bottles and heads, and externally packaging the product;
and step six, inspecting the finished products, and storing the qualified products in a finished product warehouse.
The iodine-free disinfectant is colorless, tasteless and precipitate-free liquid, has a simple formula, a good disinfection effect, no toxicity to skin or mucous membrane, low irritation, a stable effective iodine content for a long time and a long effective period.
The invention is an environment-friendly sterilization disinfectant, has extremely strong capability of killing bacteria, and has the characteristics of wide sterilization spectrum and high efficiency; the antibacterial agent can be used at normal temperature, has long antibacterial time, no side effect, low toxicity, safety and effectiveness; the paint has no corrosion to various materials; no harmful substances such as chlorine, aldehyde and the like; the packaging dosage is larger than that of the common iodine disinfectant; the disinfectant has the effects of disinfecting, moistening skin and keeping water, and simultaneously has cool and comfortable touch feeling and reduces the irritation to skin and mucous membrane.
The disinfectant of the present invention is compounded with iodine, ethanol, chlorhexidine acetate, potassium iodide, potassium iodate, mint oil and glycerin as main material. The preparation method of the Aner iodine skin mucosa disinfectant comprises the following steps: dissolving potassium iodide, iodine, chlorhexidine acetate, oleum Menthae Dementholatum and glycerol in ethanol solution, and stirring to obtain homogeneous solution; adding purified deionized water to full volume, and performing constant volume and aging; inspecting the obtained intermediate product; if the product is qualified, filling and sealing the product by using disinfectant plastic bottles and heads, and externally packaging the product; and (5) inspecting the finished product, and storing the qualified product in a finished product warehouse.
The invention is an environment-friendly sterilization disinfectant, has strong capability of killing bacteria, and has the characteristics of broad-spectrum and high-efficiency sterilization; the antibacterial agent can be used at normal temperature, has long antibacterial time, no side effect, low toxicity, safety and effectiveness; the paint has no corrosion to various materials; no harmful substances such as chlorine, aldehyde and the like; the disinfectant has the effects of disinfecting, moistening skin and keeping water, and simultaneously has cool and comfortable touch feeling and reduces the irritation to skin and mucous membrane.
Drawings
FIG. 1 is a flow chart of a method for preparing an iodine-containing skin mucosa disinfectant provided by the embodiment of the invention.
FIG. 2 is a flow chart of the production process of the iodine-containing skin mucosa disinfectant provided by the embodiment of the invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Aiming at the problem that the using effect of the existing disinfectant is not ideal, the using effect of the iodine-containing skin mucosa disinfectant provided by the invention is superior to that of the existing disinfectant.
The technical scheme of the invention is described in detail in the following with reference to the accompanying drawings.
The iodine-containing skin mucosa disinfectant provided by the embodiment of the invention comprises, by weight, 0.23% of iodine with the purity of 99%, 60% of ethanol with the purity of 95%, 0.5% of chlorhexidine acetate with the purity of 99%, 0.17% of potassium iodide with the purity of 99%, 0.15% of potassium iodate with the purity of 99%, 0.05% of peppermint oil with the purity of 50%, 3.0% of glycerol with the purity of 99%, and the balance of purified deionized water, wherein the deionized water is used for supplementing to 100%.
Every 1000Kg of the prescription of the iodine-containing skin mucosa disinfectant provided by the embodiment of the invention consists of 2.3 Kg of iodine with the purity of 99 percent, 600 Kg of ethanol with the purity of 95 percent, 5Kg of chlorhexidine acetate with the purity of 99 percent, 1.7Kg of potassium iodide with the purity of 99 percent, 1.5Kg of potassium iodide with the purity of 99 percent, 0.5Kg of peppermint oil with the purity of 50 percent, 30Kg of glycerin with the purity of 99 percent and the balance of purified deionized water which is added to 1000 Kg.
As shown in fig. 1, the preparation method of the iodine-containing skin mucosa disinfectant provided by the embodiment of the invention comprises the following steps:
s101: preparing raw materials in parts by weight: iodine with the purity of 99 percent 0.23 percent, ethanol with the purity of 95 percent 60 percent, chlorhexidine acetate with the purity of 99 percent 0.5 percent, potassium iodide with the purity of 99 percent 0.17 percent, potassium iodate with the purity of 99 percent 0.15 percent, peppermint oil with the purity of 50 percent 0.05 percent, glycerol with the purity of 99 percent 3.0 percent, and the balance of purified deionized water;
s102: dissolving potassium iodide, potassium iodate, iodine, chlorhexidine acetate, peppermint oil and glycerol in an ethanol solution, and stirring to obtain a homogeneous solution;
s103: adding purified ionized water to full volume, and performing constant volume and aging;
s104: inspecting the obtained intermediate product;
s105: if the product is qualified, filling and sealing the product by using disinfectant plastic bottles and heads, and externally packaging the product;
s106: and (5) inspecting the finished product, and storing the qualified product in a finished product warehouse.
The technical solution of the invention is further described below with reference to specific embodiments.
Example (b):
1000kg of prescription composition:
| name of raw materials | Purity of | Addition amount (Kg) | Account for the total amount (%) |
| Iodine | 99% | 2.3 | 0.23 |
| Ethanol | 95% | 600 | 60 |
| Chlorhexidine acetate | 99% | 5 | 0.5 |
| Potassium iodide | 99% | 1.7 | 0.17 |
| Potassium iodate | 99% | 1.5 | 0.15 |
| Mint oil | 50% | 0.5 | 0.05 |
| Glycerol | 99% | 30 | 3.0 |
| Deionized water | 100% | 360.5 | 36.05 |
As is well known, the hospital has an increasingly heavy workload of disinfecting the skin mucosa of a patient, the quantity of demands of general skin punctures such as dressing change in surgical operations, blood sampling and injection and the like on skin mucosa disinfectant has an increasing amount, doctors have frequent work, and therefore the skin mucosa disinfectant is required to have the characteristic of rapid sterilization. The iodine-containing disinfectant is generally applied to clinical use in hospitals, is disinfected before general skin puncture such as intramuscular injection and intravenous injection, and is used for disinfection of special parts such as operation parts, surgical dressing change, oral mucosa, lumbar puncture and blood collection. The action time is short, the disinfection action time of the skin after the operation is 2-3 minutes, the disinfection action time of the muscle vein agent before the skin puncture is 1 minute, the disinfection action time of the blood sampling part is 1 minute, and the disinfection action time of the surgical operation is 3 minutes. The use mode is convenient, and the original solution or the diluent can be directly rubbed on the skin mucosa to achieve the aim of disinfection and sterilization.
The anidine disinfectant disclosed by the invention has all the advantages of the anidine disinfectant commonly used in the market, is large in packaging dosage, long in effective period after opening the bottle, still can maintain the effective iodine content for a long time after being left unused after opening the bottle, does not influence the disinfection and sterilization effect, has the effects of moistening the skin and preserving the water after disinfection and sterilization, is cool and comfortable in touch and reduces the irritation to the skin and mucous membranes.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.
Claims (4)
1. An iodine skin mucosa disinfectant is characterized by comprising, by weight, 0.23% of iodine with the purity of 99%, 60% of ethanol with the purity of 95%, 0.5% of chlorhexidine acetate with the purity of 99%, 0.17% of potassium iodide with the purity of 99%, 0.15% of potassium iodate with the purity of 99%, 0.05% of peppermint oil with the purity of 50%, 3.0% of glycerol with the purity of 99%, and the balance of purified deionized water.
2. The iodine disinfectant for skin and mucosa as set forth in claim 1, wherein the iodine disinfectant for skin and mucosa is prepared with iodine 2.3 Kg in purity 99%, ethanol 600 Kg in purity 95%, chlorhexidine acetate 5Kg in purity 99%, potassium iodide 1.7Kg in purity 99%, potassium iodate 1.5Kg in purity 99%, peppermint oil 0.5Kg in purity 50%, glycerin 30Kg in purity 99%, and deionized water in the balance of 1000 Kg.
3. The method for preparing the iodine-containing disinfectant for skin and mucosa as set forth in claim 1, wherein the method for preparing the iodine-containing disinfectant for skin and mucosa comprises the steps of:
preparing raw materials in parts by weight: iodine with the purity of 99 percent 0.23 percent, ethanol with the purity of 95 percent 60 percent, chlorhexidine acetate with the purity of 99 percent 0.5 percent, potassium iodide with the purity of 99 percent 0.17 percent, potassium iodate with the purity of 99 percent 0.15 percent, peppermint oil with the purity of 50 percent 0.05 percent, glycerol with the purity of 99 percent 3.0 percent, and the balance of purified deionized water;
dissolving potassium iodide, potassium iodate, iodine, chlorhexidine acetate, peppermint oil and glycerol into an ethanol solution, and stirring to obtain a homogeneous solution;
adding purified ionic water to full volume, and performing constant volume and aging;
step four, inspecting the obtained intermediate product;
step five, if the product is qualified, filling and sealing the product by using disinfectant plastic bottles and heads, and externally packaging the product;
and step six, inspecting the finished products, and storing the qualified products in a finished product warehouse.
4. Use of the iodine anolam disinfectant as defined in any one of claims 1-2 for disinfecting skin and mucous membrane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010151118.XA CN111035674A (en) | 2020-03-06 | 2020-03-06 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010151118.XA CN111035674A (en) | 2020-03-06 | 2020-03-06 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111035674A true CN111035674A (en) | 2020-04-21 |
Family
ID=70230694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010151118.XA Pending CN111035674A (en) | 2020-03-06 | 2020-03-06 | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111035674A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114053299A (en) * | 2020-08-03 | 2022-02-18 | 成都中光洗消剂有限公司 | Compound iodine disinfectant and preparation method thereof |
| CN114129592A (en) * | 2021-12-06 | 2022-03-04 | 郑州大学第一附属医院 | Disinfection gel for obstetrics and gynecology department and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480044A (en) * | 2003-07-04 | 2004-03-10 | 同联集团沈阳抗生素厂 | High performance iodine disinfection liquid |
| CN102846695A (en) * | 2012-08-14 | 2013-01-02 | 青岛叁鼎卫生制品有限公司 | Cleaning disinfectant and preparation method thereof |
| CN104604934A (en) * | 2015-01-21 | 2015-05-13 | 成都科宏达科技有限公司 | Novel composite iodine disinfectant as well as preparation method and application thereof |
| CN106163577A (en) * | 2014-03-31 | 2016-11-23 | 艾欧泰克国际股份有限公司 | The stable compositions of uncomplexed iodine and using method |
| CN108324732A (en) * | 2018-03-23 | 2018-07-27 | 山东太乙制药有限公司 | A kind of skin and mucosa hand sanitizing fluid |
| CN109362797A (en) * | 2018-12-04 | 2019-02-22 | 怀化学院 | Iodic disinfecting liquid and preparation method thereof |
-
2020
- 2020-03-06 CN CN202010151118.XA patent/CN111035674A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1480044A (en) * | 2003-07-04 | 2004-03-10 | 同联集团沈阳抗生素厂 | High performance iodine disinfection liquid |
| CN102846695A (en) * | 2012-08-14 | 2013-01-02 | 青岛叁鼎卫生制品有限公司 | Cleaning disinfectant and preparation method thereof |
| CN106163577A (en) * | 2014-03-31 | 2016-11-23 | 艾欧泰克国际股份有限公司 | The stable compositions of uncomplexed iodine and using method |
| CN104604934A (en) * | 2015-01-21 | 2015-05-13 | 成都科宏达科技有限公司 | Novel composite iodine disinfectant as well as preparation method and application thereof |
| CN108324732A (en) * | 2018-03-23 | 2018-07-27 | 山东太乙制药有限公司 | A kind of skin and mucosa hand sanitizing fluid |
| CN109362797A (en) * | 2018-12-04 | 2019-02-22 | 怀化学院 | Iodic disinfecting liquid and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 林辉，等: "3种皮肤消毒液对耐药菌株抑菌效果的检测", 《现代预防医学》 * |
| 江焕贞，等: "比较安尔碘与乙醇皮肤消毒液临床应用价值", 《按摩与康复医学》 * |
| 王桂杰，等: "静脉留置针不同消毒方法的效果对比观察", 《齐鲁护理杂志》 * |
| 许方蕾，等: "氯己定醇皮肤消毒液应用于儿童浅静脉留置针的效果评价", 《中华医院感染学杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114053299A (en) * | 2020-08-03 | 2022-02-18 | 成都中光洗消剂有限公司 | Compound iodine disinfectant and preparation method thereof |
| CN114129592A (en) * | 2021-12-06 | 2022-03-04 | 郑州大学第一附属医院 | Disinfection gel for obstetrics and gynecology department and preparation method thereof |
| CN114129592B (en) * | 2021-12-06 | 2023-03-10 | 郑州大学第一附属医院 | Disinfecting gel for obstetrics and gynecology department and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2459201B1 (en) | Hydrogel formulation comprising oxidative reductive potential water | |
| RU2436568C2 (en) | Self-preserved water pharmaceutical compositions | |
| EP1896043B1 (en) | Method of using oxidative reductive potential water solution in dental applications | |
| EP2066300B2 (en) | Self-preserved aqueous pharmaceutical compositions | |
| EP3205358A1 (en) | Oxidative reductive potential water solution and method of using the same | |
| US20050196462A1 (en) | Topical formulation containing oxidative reductive potential water solution and method for using same | |
| CN111297704B (en) | Foam disinfection composition with sterilization and skin care functions and preparation method and application thereof | |
| AU2011200390A1 (en) | Oxidative reductive potential water solution, processes for producing same and methods of using the same | |
| CN111035674A (en) | Aner iodine skin mucosa disinfectant as well as preparation method and application thereof | |
| CN108566954A (en) | A kind of disinfectant and its preparation method and application | |
| CN111214393A (en) | Hand-washing-free disinfection gel and preparation method and application thereof | |
| CN111437276A (en) | A pharmaceutical composition for killing fungi or bacteria | |
| TW548261B (en) | Composition and method for inhibiting uptake of biguanide disinfectants by poly(ethylene) | |
| US20100021561A1 (en) | Self-preserved aqueous pharmaceutical compositions | |
| CN104434994A (en) | Mucocutaneous disinfectant | |
| CA2727735A1 (en) | Disinfectant and/or bactericidal aqueous compositions | |
| CN111202088A (en) | Chlorhexidine acetate disinfectant and preparation method and application thereof | |
| CN107582737A (en) | A kind of compound chlorohexidene oral-cavity disinfectant and preparation method thereof | |
| CN113521042A (en) | Alcohol-free wash-free virus inactivation disinfectant special for children and preparation method thereof | |
| CN108272649B (en) | IgY-containing clear mouthwash and preparation method thereof | |
| US20170196783A1 (en) | Pharyngeal or buccal cavity rinse and process of use thereof | |
| CN111264566A (en) | Household disinfectant and preparation method thereof | |
| JP2022536927A (en) | Compositions, kits, methods and uses for preventing microbial growth | |
| Anger et al. | Preservation of Dispersed Systems | |
| Eryilmaz | New generation disinfectants |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |