CN1471519A - 氨基烯基苯甲酰基-苯并呋喃或苯并噻吩,它们的制备方法与含有它们的组合物 - Google Patents
氨基烯基苯甲酰基-苯并呋喃或苯并噻吩,它们的制备方法与含有它们的组合物 Download PDFInfo
- Publication number
- CN1471519A CN1471519A CNA018177654A CN01817765A CN1471519A CN 1471519 A CN1471519 A CN 1471519A CN A018177654 A CNA018177654 A CN A018177654A CN 01817765 A CN01817765 A CN 01817765A CN 1471519 A CN1471519 A CN 1471519A
- Authority
- CN
- China
- Prior art keywords
- formula
- compound
- group
- cumarone
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR00/10835 | 2000-08-23 | ||
| FR0010835A FR2813307B1 (fr) | 2000-08-23 | 2000-08-23 | Aminoalkenylbenzoyl-benzofurannes ou benzothiophenes, leur procede de preparation et les compositions les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1471519A true CN1471519A (zh) | 2004-01-28 |
Family
ID=8853675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA018177654A Pending CN1471519A (zh) | 2000-08-23 | 2001-08-23 | 氨基烯基苯甲酰基-苯并呋喃或苯并噻吩,它们的制备方法与含有它们的组合物 |
Country Status (25)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107827849A (zh) * | 2017-11-14 | 2018-03-23 | 沈阳药科大学 | 6‑[2‑羟基‑3‑(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
| CN107857748A (zh) * | 2017-11-14 | 2018-03-30 | 沈阳药科大学 | 5‑[2‑羟基‑3‑(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
| CN107935972A (zh) * | 2017-11-14 | 2018-04-20 | 沈阳药科大学 | 5‑[2‑羟基‑3‑(异丙胺基)丙氧基]苯并呋喃类衍生物及其应用 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG173014A1 (en) | 2009-01-16 | 2011-08-29 | Exelixis Inc | Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quin0lin-4-yl] oxy}phenyl)-n' - (4 -fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer |
| AU2011202542A1 (en) | 2010-07-14 | 2012-02-02 | Indian Institute Of Science | Benzothiophene carboxamide compounds, composition and applications thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3248401A (en) * | 1966-04-26 | Diethylaminoe hoxybenzoyl benzofurans | ||
| US4831054A (en) * | 1988-04-18 | 1989-05-16 | Taro Pharmaceuticals, Ltd. | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia |
| AT391316B (de) * | 1988-09-15 | 1990-09-25 | Ebewe Arzneimittel | Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
| US5364880A (en) * | 1993-06-16 | 1994-11-15 | Advanced Therapies, Inc. | Compound for treatment of cardiac arrhythmia, synthesis, and methods of use |
| US6756388B1 (en) * | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| US5622974A (en) * | 1995-03-10 | 1997-04-22 | Eli Lilly And Company | α-substituted-3-benzyl-benzofurans |
| US5523309A (en) * | 1995-03-10 | 1996-06-04 | Eli Lilly And Company | Benzofuran pharmaceutical compounds |
| CA2220991A1 (en) * | 1995-06-26 | 1997-01-16 | Eli Lilly And Company | Benzothiophene compounds |
| US5827876A (en) * | 1996-04-09 | 1998-10-27 | American Home Products Corporation | Inhibition of bone loss by 3-(4-acrylamidobenzoyl) benzo b!-thiophenes |
| AU3171099A (en) * | 1998-04-17 | 1999-11-08 | Senga Pharmaceutical Laboratory Inc. | 1-heteroindene derivatives and medicinal composition containing the same |
-
2000
- 2000-08-23 FR FR0010835A patent/FR2813307B1/fr not_active Expired - Fee Related
-
2001
- 2001-08-23 WO PCT/FR2001/002656 patent/WO2002016338A1/fr not_active Application Discontinuation
- 2001-08-23 EA EA200300063A patent/EA200300063A1/ru unknown
- 2001-08-23 MX MXPA03001592A patent/MXPA03001592A/es not_active Application Discontinuation
- 2001-08-23 IL IL15363701A patent/IL153637A0/xx unknown
- 2001-08-23 DE DE60104866T patent/DE60104866T2/de not_active Expired - Lifetime
- 2001-08-23 AT AT01963120T patent/ATE273293T1/de not_active IP Right Cessation
- 2001-08-23 HU HU0302892A patent/HUP0302892A3/hu unknown
- 2001-08-23 SK SK211-2003A patent/SK2112003A3/sk unknown
- 2001-08-23 AU AU2001284154A patent/AU2001284154A1/en not_active Abandoned
- 2001-08-23 CA CA002415846A patent/CA2415846A1/fr not_active Abandoned
- 2001-08-23 OA OA1200300034A patent/OA12358A/fr unknown
- 2001-08-23 PL PL01362123A patent/PL362123A1/xx not_active Application Discontinuation
- 2001-08-23 US US10/362,291 patent/US6946483B2/en not_active Expired - Lifetime
- 2001-08-23 JP JP2002521439A patent/JP4918209B2/ja not_active Expired - Fee Related
- 2001-08-23 EP EP01963120A patent/EP1315708B1/fr not_active Expired - Lifetime
- 2001-08-23 CN CNA018177654A patent/CN1471519A/zh active Pending
- 2001-08-23 CZ CZ2003520A patent/CZ2003520A3/cs unknown
- 2001-08-23 BR BR0113350-0A patent/BR0113350A/pt not_active IP Right Cessation
- 2001-08-23 KR KR10-2003-7002619A patent/KR20030023768A/ko not_active Application Discontinuation
-
2003
- 2003-01-13 IS IS6676A patent/IS6676A/is unknown
- 2003-01-28 ZA ZA200300746A patent/ZA200300746B/xx unknown
- 2003-02-13 BG BG107553A patent/BG107553A/xx unknown
- 2003-02-17 MA MA27043A patent/MA26944A1/fr unknown
- 2003-02-20 NO NO20030801A patent/NO20030801L/no not_active Application Discontinuation
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107827849A (zh) * | 2017-11-14 | 2018-03-23 | 沈阳药科大学 | 6‑[2‑羟基‑3‑(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
| CN107857748A (zh) * | 2017-11-14 | 2018-03-30 | 沈阳药科大学 | 5‑[2‑羟基‑3‑(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
| CN107935972A (zh) * | 2017-11-14 | 2018-04-20 | 沈阳药科大学 | 5‑[2‑羟基‑3‑(异丙胺基)丙氧基]苯并呋喃类衍生物及其应用 |
| CN107857748B (zh) * | 2017-11-14 | 2020-06-02 | 沈阳药科大学 | 5-[2-羟基-3-(烷胺基)丙氧基]苯并呋喃类化合物及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0302892A2 (hu) | 2003-12-29 |
| EP1315708B1 (fr) | 2004-08-11 |
| US6946483B2 (en) | 2005-09-20 |
| DE60104866D1 (de) | 2004-09-16 |
| ATE273293T1 (de) | 2004-08-15 |
| CZ2003520A3 (cs) | 2003-05-14 |
| ZA200300746B (en) | 2004-02-10 |
| MA26944A1 (fr) | 2004-12-20 |
| EP1315708A1 (fr) | 2003-06-04 |
| SK2112003A3 (en) | 2003-08-05 |
| US20030187060A1 (en) | 2003-10-02 |
| WO2002016338A1 (fr) | 2002-02-28 |
| WO2002016338A8 (fr) | 2002-05-10 |
| AU2001284154A1 (en) | 2002-03-04 |
| EA200300063A1 (ru) | 2003-08-28 |
| HUP0302892A3 (en) | 2005-02-28 |
| NO20030801D0 (no) | 2003-02-20 |
| IS6676A (is) | 2003-01-13 |
| BG107553A (en) | 2004-01-30 |
| JP2004506726A (ja) | 2004-03-04 |
| BR0113350A (pt) | 2003-07-08 |
| IL153637A0 (en) | 2003-07-06 |
| KR20030023768A (ko) | 2003-03-19 |
| OA12358A (fr) | 2006-05-16 |
| MXPA03001592A (es) | 2003-09-10 |
| NO20030801L (no) | 2003-04-23 |
| CA2415846A1 (fr) | 2002-02-28 |
| PL362123A1 (en) | 2004-10-18 |
| DE60104866T2 (de) | 2005-10-20 |
| FR2813307B1 (fr) | 2002-11-08 |
| FR2813307A1 (fr) | 2002-03-01 |
| JP4918209B2 (ja) | 2012-04-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |