CN1458925A - 亲脂性或两亲性闪烁剂和它们在测试中的应用 - Google Patents

亲脂性或两亲性闪烁剂和它们在测试中的应用 Download PDF

Info

Publication number
CN1458925A
CN1458925A CN01815712A CN01815712A CN1458925A CN 1458925 A CN1458925 A CN 1458925A CN 01815712 A CN01815712 A CN 01815712A CN 01815712 A CN01815712 A CN 01815712A CN 1458925 A CN1458925 A CN 1458925A
Authority
CN
China
Prior art keywords
scintillator
molecule
scintillator molecule
cell
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN01815712A
Other languages
English (en)
Chinese (zh)
Inventor
R·Z·科兹洛斯基
J·M·布莱克-伯恩
J·D·萨瑟兰
S·J·卡利福德
A·J·萨瑟兰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sense Proteomic Ltd
Original Assignee
Sense Proteomic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0020503A external-priority patent/GB0020503D0/en
Application filed by Sense Proteomic Ltd filed Critical Sense Proteomic Ltd
Publication of CN1458925A publication Critical patent/CN1458925A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Materials Engineering (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN01815712A 2000-08-18 2001-08-17 亲脂性或两亲性闪烁剂和它们在测试中的应用 Pending CN1458925A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0020503.9 2000-08-18
GB0020503A GB0020503D0 (en) 2000-08-18 2000-08-18 Compounds
US24799400P 2000-11-14 2000-11-14
US60/247,994 2000-11-14

Publications (1)

Publication Number Publication Date
CN1458925A true CN1458925A (zh) 2003-11-26

Family

ID=26244864

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01815712A Pending CN1458925A (zh) 2000-08-18 2001-08-17 亲脂性或两亲性闪烁剂和它们在测试中的应用

Country Status (10)

Country Link
EP (1) EP1315707A1 (ko)
JP (1) JP2004506754A (ko)
KR (1) KR20030066601A (ko)
CN (1) CN1458925A (ko)
AU (1) AU2001278633A1 (ko)
BR (1) BR0113328A (ko)
CA (1) CA2420006A1 (ko)
GB (1) GB2383329A (ko)
IL (1) IL154485A0 (ko)
WO (1) WO2002014290A1 (ko)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104327005A (zh) * 2014-10-21 2015-02-04 华烁科技股份有限公司 闪烁纯级别的2,5-二苯基噁唑的制备方法
CN113195103A (zh) * 2018-10-21 2021-07-30 堪萨斯大学 用于生成治疗递送平台的方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553559B2 (en) * 2005-12-21 2009-06-30 Lg Display Co., Ltd. Hexatriene derivatives for use as blue emitting materials for organic electroluminescent devices
EP1892530A1 (en) * 2006-08-25 2008-02-27 Boehringer Ingelheim Pharma GmbH & Co. KG Method for determining transport activity of a transport protein
WO2020197032A1 (ko) * 2019-03-26 2020-10-01 동국대학교 산학협력단 신틸레이터 조성물 및 이를 이용하는 신틸레이터
KR102288775B1 (ko) * 2019-03-26 2021-08-12 동국대학교 산학협력단 신틸레이터 조성물 및 이를 이용하는 신틸레이터

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63227576A (ja) * 1987-03-13 1988-09-21 Hamamatsu Photonics Kk ジフエニルオキサゾ−ル誘導体とその製造方法およびその利用方法
GB2342350A (en) * 1998-10-05 2000-04-12 Univ Nottingham Trent Solid supports containing oxazole scintillants

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104327005A (zh) * 2014-10-21 2015-02-04 华烁科技股份有限公司 闪烁纯级别的2,5-二苯基噁唑的制备方法
CN104327005B (zh) * 2014-10-21 2016-08-24 华烁科技股份有限公司 2,5-二苯基噁唑的制备方法
CN113195103A (zh) * 2018-10-21 2021-07-30 堪萨斯大学 用于生成治疗递送平台的方法

Also Published As

Publication number Publication date
KR20030066601A (ko) 2003-08-09
GB0306216D0 (en) 2003-04-23
AU2001278633A1 (en) 2002-02-25
IL154485A0 (en) 2003-09-17
GB2383329A (en) 2003-06-25
EP1315707A1 (en) 2003-06-04
WO2002014290A1 (en) 2002-02-21
BR0113328A (pt) 2003-07-29
JP2004506754A (ja) 2004-03-04
CA2420006A1 (en) 2002-02-21

Similar Documents

Publication Publication Date Title
CN1173954C (zh) 与磷酸酶反应产生化学发光的化合物、组合物和方法
CN1665790A (zh) 用于检测和分离磷酸化分子的组合物及方法
CN1031879C (zh) 腺嘌呤三磷酸类似物的制备方法
CN1314682C (zh) 抑制由α4整合素调介的白血球粘附的杂环化合物
CN1832939A (zh) 用于治疗癌症或病毒病的三杂环化合物、组合物和方法
CN1871233A (zh) 新型螯合剂和螯合物及其应用
Merkel et al. Scope and limitations of typical copper-free bioorthogonal reactions with DNA: reactive 2′-deoxyuridine triphosphates for postsynthetic labeling
CN1706855A (zh) 核苷酸膦酸酯类似物前药及其筛选和制备方法
CN1353719A (zh) 新的含磷前药
CN1819829A (zh) 作为促性激素释放激素受体拮抗剂的嘧啶-2,4-二酮衍生物
CN1151209A (zh) 用双-二阳离子芳基呋喃荧光检测核酸及细胞骨架成分的方法
CN1209060A (zh) 玻连蛋白受体拮抗剂
CN1216531A (zh) 用作内皮缩血管肽受体拮抗剂的吲哚衍生物
CN101068577A (zh) 施陶丁格连接在用于显像和治疗的显像和治疗目的试剂盒中的应用
CN1307571A (zh) 胍衍生物
CN100343668C (zh) 荧光标识化合物及其应用
CN1652789A (zh) 抑制由α4整合素介导的白细胞粘附的杂芳基化合物
JPH10508846A (ja) ハロアルコキシ基を有する新規な1,2−ジオキセタン化合物、その調製方法及びその用途
CN1606551A (zh) 作为雌激素制剂的取代的2-苯基苯并呋喃
CN1458925A (zh) 亲脂性或两亲性闪烁剂和它们在测试中的应用
CN1518536A (zh) 标记试剂,合成该试剂的方法以及检测生物分子的方法
CN1044911C (zh) 制备前体药的方法
CN1042149A (zh) 四氢化嘧啶及其制备和用途
CN100344647C (zh) 磷酸化肽的标记方法及选择吸附方法,使用于该方法的配位化合物、该配位化合物的制造方法及该配位化合物的原料化合物
CN1085901A (zh) 制备含咪唑并哒嗪衍生物的抗肿瘤药物组合物的方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication