CN1438981A - 制备r－1－(芳氧基)丙－2－醇的方法 - Google Patents

制备r－1－(芳氧基)丙－2－醇的方法 Download PDF

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Publication number
CN1438981A
CN1438981A CN01808380A CN01808380A CN1438981A CN 1438981 A CN1438981 A CN 1438981A CN 01808380 A CN01808380 A CN 01808380A CN 01808380 A CN01808380 A CN 01808380A CN 1438981 A CN1438981 A CN 1438981A
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CN
China
Prior art keywords
aryloxy
propane
trialkylsiloxy
propan
catalyzer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN01808380A
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English (en)
Chinese (zh)
Inventor
J·F·拉罗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shasun Pharma Solutions Inc
Original Assignee
Rhodia Chirex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Chirex Inc filed Critical Rhodia Chirex Inc
Publication of CN1438981A publication Critical patent/CN1438981A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/02—Preparation of ethers from oxiranes
    • C07C41/03—Preparation of ethers from oxiranes by reaction of oxirane rings with hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B51/00—Introduction of protecting groups or activating groups, not provided for in the preceding groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1884—Preparation; Treatments not provided for in C07F7/20 by dismutation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CN01808380A 2000-04-21 2001-04-20 制备r－1－(芳氧基)丙－2－醇的方法 Pending CN1438981A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19894200P 2000-04-21 2000-04-21
US60/198,942 2000-04-21

Publications (1)

Publication Number Publication Date
CN1438981A true CN1438981A (zh) 2003-08-27

Family

ID=22735535

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01808380A Pending CN1438981A (zh) 2000-04-21 2001-04-20 制备r－1－(芳氧基)丙－2－醇的方法

Country Status (7)

Country Link
US (1) US6448449B2 (enExample)
EP (1) EP1280753A1 (enExample)
JP (1) JP2003531184A (enExample)
KR (1) KR20020097223A (enExample)
CN (1) CN1438981A (enExample)
CA (1) CA2406215A1 (enExample)
WO (1) WO2001081286A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112079958A (zh) * 2019-06-12 2020-12-15 中国石化扬子石油化工有限公司 一种碳五共聚石油树脂的制备方法

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ES2231275T3 (es) 1999-10-08 2005-05-16 Affinium Pharmaceuticals, Inc. Inhibidores de fab i.
AU2001268459A1 (en) * 2000-06-14 2001-12-24 Sleep Solutions, Inc. Secure test and test result delivery system
JP4387804B2 (ja) * 2001-04-06 2009-12-24 アフィニアム・ファーマシューティカルズ・インコーポレイテッド ＦａｂＩ阻害剤
PT1575951E (pt) 2002-12-06 2014-09-15 Debiopharm Int Sa Compostos heterocíclicos, métodos para os preparar e sua utilização em terapia
EP1608377B1 (en) 2003-03-17 2008-10-01 Affinium Pharmaceuticals, Inc. Pharmaceutical compositions comprising inhibitors of fab i and further antibiotics
US8450307B2 (en) * 2004-06-04 2013-05-28 Affinium Pharmaceuticals, Inc. Therapeutic agents, and methods of making and using the same
US20090156578A1 (en) * 2005-12-05 2009-06-18 PAULS Henry 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents
EP2054422B1 (en) 2006-07-20 2017-06-14 Debiopharm International SA Acrylamide derivatives as fab i inhibitors
WO2008098374A1 (en) * 2007-02-16 2008-08-21 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab i inhibitors
KR101503745B1 (ko) * 2010-02-25 2015-03-19 에스케이이노베이션 주식회사 나이트레이트 음이온의 이산화탄소/에폭사이드 공중합 촉매 시스템
EP2861608B8 (en) 2012-06-19 2019-06-19 Debiopharm International SA Prodrug derivatives of (e)-n-methyl-n-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
DK3419628T3 (da) 2016-02-26 2021-01-11 Debiopharm Int Sa Medikament til behandling af diabetiske fodinfektioner
ES2944535T3 (es) 2019-02-14 2023-06-22 Debiopharm Int Sa Formulación de afabicina, método para preparar la misma
UA129222C2 (uk) 2019-06-14 2025-02-12 Дебіофарм Інтернешнл С.А. Лікарський засіб і його застосування для лікування бактеріальних інфекцій, пов'язаних з біоплівкою

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
GB8525953D0 (en) * 1985-10-21 1985-11-27 Mcneilab Inc Preparation of galactopyranoside
GB8525954D0 (en) * 1985-10-21 1985-11-27 Mcneilab Inc Chlorination of carbohydrates &c alcohols
JP2620290B2 (ja) * 1988-03-11 1997-06-11 旭電化工業株式会社 シリルオキシ基を有するアリールエーテル化合物の製造法
AU4376589A (en) * 1988-11-07 1990-05-10 Gist-Brocades N.V. Optically active benzoxazines and benzothiazines
US5637739A (en) 1990-03-21 1997-06-10 Research Corporation Technologies, Inc. Chiral catalysts and catalytic epoxidation catalyzed thereby
US5559222A (en) * 1995-02-03 1996-09-24 Eli Lilly And Company Preparation of 1-(2'-deoxy-2',2'-difluoro-D-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose
US5665890A (en) * 1995-03-14 1997-09-09 President And Fellows Of Harvard College Stereoselective ring opening reactions
ATE249467T1 (de) 1997-07-10 2003-09-15 Du Pont Herstellung von optisch aktiven halohydrintrialkylsilylethern
JPH11269131A (ja) 1998-03-20 1999-10-05 Asahi Glass Co Ltd １−アシルオキシ−２−プロパノールの製造方法
JPH11279100A (ja) 1998-03-25 1999-10-12 Asahi Glass Co Ltd 光学活性な１−置換−２−プロパノールの製造方法
JP2000063314A (ja) 1998-08-14 2000-02-29 Asahi Glass Co Ltd 光学活性な１−置換−２−プロパノールの製造方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112079958A (zh) * 2019-06-12 2020-12-15 中国石化扬子石油化工有限公司 一种碳五共聚石油树脂的制备方法

Also Published As

Publication number Publication date
CA2406215A1 (en) 2001-11-01
WO2001081286A1 (en) 2001-11-01
JP2003531184A (ja) 2003-10-21
EP1280753A1 (en) 2003-02-05
US20020007090A1 (en) 2002-01-17
US6448449B2 (en) 2002-09-10
KR20020097223A (ko) 2002-12-31

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