CN1386531A - Chinese medicine for treating syringomyelia - Google Patents
Chinese medicine for treating syringomyelia Download PDFInfo
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- CN1386531A CN1386531A CN02109814A CN02109814A CN1386531A CN 1386531 A CN1386531 A CN 1386531A CN 02109814 A CN02109814 A CN 02109814A CN 02109814 A CN02109814 A CN 02109814A CN 1386531 A CN1386531 A CN 1386531A
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- angelicae sinensis
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- 206010010356 Congenital anomaly Diseases 0.000 description 1
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine for treating syringomyelia, lateral sclerosis, chronic spondylitis, arachnoid adhesion, etc is prepared from 13 Chinese-medicinal materials including pilose antler, prepared rehmannia root, wolfberry fruit, ginseng, astragalus root, etc. Its advantages are high curative effect, no toxic by-effect and no recurrence.
Description
Technical field:
The present invention relates to the medicine of diseases of spinal cord, especially a kind of Chinese medicine preparation for the treatment of syringomyelia belongs to Chinese traditional treatment spinal cord class disease pharmaceutical technology.
Background technology:
At present, in spinal cord class disease medically, clinical symptoms complexity, patient's misery does not still have ideal medicine.With regard to syringomyelia, medicine analgesics commonly used, vitamin B group, coenzyme A or employing radiotherapy, operation decompression method.Described Therapeutic Method does not all have obvious curative effects to recovering neurocyte, so record " primary disease does not still have specific treatment at present " on the doctor trained in Western medicine book.
Summary of the invention:
The invention provides a kind of Chinese medicine preparation for the treatment of syringomyelia, can promote the absorption of hydrocrania, empty formation and development in the marrow is dwindled in restriction, and is evident in efficacy, has no side effect.
The technology of the present invention solution is based on the pathogeny and the Therapeutic Principle of the right diseases of spinal cord of China's Chinese medicine, with reference to modern medical theory, with benefiting essence and marrow, wither in living marrow strengthening spleen and nourishing blood, supporing yang town, and excited spinal nerves is main, promote blood circulation relieving convulsion and make laws, select pure natural Chinese herbal medicine and animal drugs compatibility for use,, screen through strictness by the theory of Chinese medical science prescription, concoct respectively, combine in conjunction with modern advanced technologies method for making.Following consumption is weight portion, and basic recipe is as follows:
Cornu Cervi Pantotrichum 30～40, Radix Rehmanniae Preparata 40～55, Fructus Lycii 40～55, Rhizoma Polygonati 40～55, Radix Ginseng 40～55, the Radix Astragali 45～60, Caulis Spatholobi 35～45, crust halberd 45～55, Radix Salviae Miltiorrhizae 45～55, Radix Angelicae Sinensis 35～45, Rhizoma Chuanxiong 28～32, Poria 35～45, Cordyceps 20～25.
Its preferred weight proportioning is:
Cornu Cervi Pantotrichum 38kg, Radix Angelicae Sinensis 40kg, Rhizoma Chuanxiong 30kg, Radix Salviae Miltiorrhizae 45kg, Radix Rehmanniae Preparata 55kg, Fructus Lycii 50kg, Rhizoma Polygonati 50kg, Radix Ginseng 45kg, Radix Astragali 58kg, Caulis Spatholobi 45kg, crust halberd 50kg, Radix Salviae Miltiorrhizae 50kg, Poria 45kg, Cordyceps 22kg.
Processing procedure:
Take by weighing above medicine according to the above ratio.At first Cornu Cervi Pantotrichum is used 100 ℃ of dry heat sterilizations of baking oven, make fine powder with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae mixed grinding,, add four times of water gagings and decoct twice again with all the other medicament mixed, each 2 hours, collecting decoction filters, and filtrate is concentrated into relative density 1.20～1.25 (80～85 ℃), with above-mentioned fine powder mix homogeneously, xeraphium becomes fine powder, is that wetting agent is made granule with 60% ethanol, drying, granulate, sterilization packaging.
The present invention can adopt the pharmaceutical preparation technology on the pharmaceutics to make any dosage form.
The Fang Xieyu pharmacology analysis: the used 13 flavor Chinese medicines of the present invention, major part has kidney tonifying, essence replenishing, gives birth to the effect of marrow.Consider that myelopathy mostly is kidney spleen deficiency, so in the side, added relevant invigorating the spleen and benefiting QI, the medicine of granulation promoting.Marrow is given birth in the Cornu Cervi Pantotrichum replenishing essence; The Radix Rehmanniae Preparata blood enriching and generation of vital essence promoting, fill out bone marrow; Fructus Lycii liver nourishing kidney tonifying, living through supporing yang; The Rhizoma Polygonati replenishing essence, help muscles and bones; Radix Ginseng invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid; Radix Astragali tonifying Qi and lifting yang; The Caulis Spatholobi promoting the circulation of blood of enriching blood; The crust halberd is mended the lean kidney; Radix Salviae Miltiorrhizae removing blood stasis tissue regeneration promoting; Chinese Angelica blood replonishing is enriched blood; Rhizoma Chuanxiong nourishes blood, and is gas medicine in the blood; Cordyceps is mended the lean kidney; The sharp key of Poria eliminating dampness by diuresis.
The combination principle of preparation of the present invention: Cornu Cervi Pantotrichum, Radix Rehmanniae Preparata, Cordyceps, Fructus Lycii, crust halberd are the principal agent of the kidney invigorating.With Radix Angelicae Sinensis, Rhizoma Polygonati, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Caulis Spatholobi is mutual reinforcement between, encourages curative effect mutually, serves the same role.With Radix Ginseng, the Radix Astragali, the mutual-assistance of Poria position,, promote the full of congenital kidney essense by the tonification taste day after tomorrow.
Indication comprises syringomyelia, lateral sclerosis disease, chronic myelitis, arachnoid adhesion, trauma of spinal cord paralysis.
Usage and consumption: oral.Formulation rate of the present invention can be according to variations such as route of administration, patient age, body weight, disease type and the orders of severity, and daily dose is 10～16 grams.Each 5～7g, secondary took with eliminating cold for resuscitation water or yellow wine and to take after mixing it with water every day.
Good effect of the present invention is: preparation is that animal drugs and pure Chinese herbal medicine are made, and toxic and side effects is little, and treating both the principal and secondary aspects of a disease is evident in efficacy, and clinical symptom disappearance is rapid, cures the no rebound phenomena in back.
For showing the therapeutic effect of medicine of the present invention, selected 200 examples are the patient who suffers from the syringomyelia disease through nuclear magnetic resonance diagnosis, take medicine of the present invention and treat, and carry out statistical analysis through system's clinical observation and are summarized as follows:
One, curative effect determinate standard
Clinical cure: various symptoms all disappear.
Produce effects: refer to possess with the next item down person 1, sensory disturbance is most of recovers normal; 2, flesh appearance, muscular strength partly recover normal; 3, vegetative nerve functional disturbance is most of recovers normal; 4, pathologic reflex disappears.
Effectively: refer to possess with the next item down person, 1, subjective symptoms partly takes a turn for the better or conscious trouble limb is strong, flexibly; 2, sensory disturbance partly takes a turn for the better; 3, vegetative nerve functional disturbance partly takes a turn for the better.
Invalid: various symptoms and sign do not have change.
Two, therapeutic outcome
200 routine syringomyelia patients, clinical cure 5 examples (2.5%); Produce effects 131 examples (65.6%); Invalid 7 examples of effective 57 examples (28.5%) (3.5%).Total effective rate is 96.5%.
Model case:
1, Wang, the woman, 27 years old, medical record number 00242, left hemianesthesia 5 years, two lower extremity paralysiss 2 years, 1988 through MRI inspection C
2-T
8Hernia is (MRI number: 04199), take medicine of the present invention in January, 90 in hospital, treated 3 months under the syringomyelia companion tonsil of cerebellum, outpatient service continues to take this medicine treatment 2 years, and the symptom Signs is recovered normally fully, the unable disappearance of numb limbs and tense tendons, sensation is normal, and it is normal that lower limb amyotrophy is recovered.Check MRI (MRI number: 41068), except that myelocoele slightly wide, surplus no abnormal through Zhongshan Hospital Attached to Medical College of Fudan Univ. June calendar year 2001.
2, Wang, man, 48 years old, outpatient service number: 99807
The unable companion's pain of two upper limb numbness 3 years, in February, 95 through the Yellow River, the Zhengzhou City MRI of hospital check (MRIH number: 7787), C
7-T
1Syringomyelia.Outpatient service in July, 96 medication treatment is 2 years, clinical symptom disappearance.August calendar year 2001, (MRI numbers 9918: no abnormality seen in the spinal cord in the Yellow River, Zhengzhou City hospital check MRI.
3, Zhang, man, 15 years old, admission number: 00880
Right hemianesthesia joint aches 6 years was checked through the MRI of Shanghai Long March Hospital: C in 92 years
2-T
12Hernia under the syringomyelia companion tonsil of cerebellum.Medicine of the present invention is taken in JIUYUE, 96 outpatient service, and each 6 grams are treated half a year every day 2 times, and 97 years through first MRI of hospital of Xinjiang Medical College Affiliated Hospital inspection, (MRI number: 11035) C
2-T
12Syringomyelia disappears substantially.In July, 97, hospitalization was 1 month, and the symptom Signs disappears, and clinical cure goes out hospital.
The specific embodiment:
Embodiment 1
Take by weighing Cornu Cervi Pantotrichum 30kg, Radix Rehmanniae Preparata 45kg, Fructus Lycii 40kg, Rhizoma Polygonati 50kg, Radix Ginseng 55kg, Radix Astragali 50kg, Caulis Spatholobi 35kg, crust halberd 48kg, Radix Salviae Miltiorrhizae 43kg, Radix Angelicae Sinensis 40kg, Rhizoma Chuanxiong 28kg, Poria 42kg, Cordyceps 20kg respectively.Earlier Cornu Cervi Pantotrichum is used 100 ℃ of dry heat sterilizations of baking oven, make fine powder with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae mixed grinding,, add four times of water gagings and decoct twice again with all the other medicament mixed, each 2 hours, collecting decoction filters, and filtrate is concentrated into relative density 1.20～1.25 (80～85 ℃), with above-mentioned fine powder mix homogeneously, xeraphium becomes fine powder, is that wetting agent is made granule with 60% ethanol, drying, granulate, sterilization packaging.
Embodiment 2
Cornu Cervi Pantotrichum 38kg is used 100 ℃ of dry heat sterilizations of baking oven, with Radix Angelicae Sinensis 40kg, Rhizoma Chuanxiong 30kg, Radix Salviae Miltiorrhizae 45kg mixed grinding is made fine powder, again with Radix Rehmanniae Preparata 55kg, Fructus Lycii 50kg, Rhizoma Polygonati 50kg, Radix Ginseng 45kg, Radix Astragali 58kg, Caulis Spatholobi 45kg, crust halberd 50kg, Radix Salviae Miltiorrhizae 50kg, Poria 45kg, all the other medicament mixed such as Cordyceps 22kg, adding four times of water gagings decocts twice, each 2 hours, collecting decoction, filter, filtrate is concentrated into relative density 1.20～1.25 (80～85 ℃), with above-mentioned fine powder mix homogeneously, xeraphium becomes fine powder, is that wetting agent is made granule, drying with 60% ethanol, granulate, sterilization packaging.
Claims (4)
1, a kind of Chinese medicine preparation for the treatment of syringomyelia is characterized in that it being the medicine of being made by ratio of weight and the number of copies by following Chinese medicine:
Cornu Cervi Pantotrichum 30～40, Radix Rehmanniae Preparata 40～55, Fructus Lycii 40～55, Rhizoma Polygonati 40～55, Radix Ginseng 40～55, the Radix Astragali 45～60, Caulis Spatholobi 35～45, crust halberd 45～55, Radix Salviae Miltiorrhizae 45～55, Radix Angelicae Sinensis 35～45, Rhizoma Chuanxiong 28～32, Poria 35～45, Cordyceps 20～25.
2, Chinese medicine preparation according to claim 1, its preferred weight proportioning is:
Cornu Cervi Pantotrichum 38kg, Radix Angelicae Sinensis 40kg, Rhizoma Chuanxiong 30kg, Radix Salviae Miltiorrhizae 45kg, Radix Rehmanniae Preparata 55kg, Fructus Lycii 50kg, Rhizoma Polygonati 50kg, Radix Ginseng 45kg, Radix Astragali 58kg, Caulis Spatholobi 45kg, crust halberd 50kg, Radix Salviae Miltiorrhizae 50kg, Poria 45kg, Cordyceps 22kg.
3,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to claim 1,2 described Chinese medicine preparation.
4, the preparation method of Chinese medicine preparation according to claim 1 may further comprise the steps:
Cornu Cervi Pantotrichum is used 100 ℃ of dry heat sterilizations of baking oven, make fine powder with Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae mixed grinding,, add four times of water gagings and decoct twice again with all the other medicament mixed, each 2 hours, collecting decoction filters, and filtrate is concentrated into relative density 1.20～1.25 (80～85 ℃), with above-mentioned fine powder mix homogeneously, xeraphium becomes fine powder, is that wetting agent is made granule with 60% ethanol, drying, granulate, sterilization packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB02109814XA CN1172699C (en) | 2002-05-22 | 2002-05-22 | Chinese medicine for treating syringomyelia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB02109814XA CN1172699C (en) | 2002-05-22 | 2002-05-22 | Chinese medicine for treating syringomyelia |
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| Publication Number | Publication Date |
|---|---|
| CN1386531A true CN1386531A (en) | 2002-12-25 |
| CN1172699C CN1172699C (en) | 2004-10-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB02109814XA Expired - Fee Related CN1172699C (en) | 2002-05-22 | 2002-05-22 | Chinese medicine for treating syringomyelia |
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| Country | Link |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836345A (en) * | 2012-08-29 | 2012-12-26 | 马少川 | Traditional Chinese medicine formula of rehabilitation powder for syringomyelia |
| CN104800724A (en) * | 2015-04-20 | 2015-07-29 | 鞠芳 | Drug for improving toxic or side effects caused after tumor chemotherapy |
| CN105106761A (en) * | 2015-09-30 | 2015-12-02 | 山东大学齐鲁医院 | Traditional Chinese medicine for treating spinal cord injury and preparation method of traditional Chinese medicine |
| WO2023035867A1 (en) * | 2021-09-08 | 2023-03-16 | 宁夏杞肽科技有限公司 | Use of goji glycopeptide in preparation of drug for preventing and/or treating amyotrophic lateral sclerosis |
-
2002
- 2002-05-22 CN CNB02109814XA patent/CN1172699C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102836345A (en) * | 2012-08-29 | 2012-12-26 | 马少川 | Traditional Chinese medicine formula of rehabilitation powder for syringomyelia |
| CN104800724A (en) * | 2015-04-20 | 2015-07-29 | 鞠芳 | Drug for improving toxic or side effects caused after tumor chemotherapy |
| CN104800724B (en) * | 2015-04-20 | 2016-02-03 | 青岛市中心医院 | Improve the medicine of toxicity after chemotherapy of tumors |
| CN105106761A (en) * | 2015-09-30 | 2015-12-02 | 山东大学齐鲁医院 | Traditional Chinese medicine for treating spinal cord injury and preparation method of traditional Chinese medicine |
| WO2023035867A1 (en) * | 2021-09-08 | 2023-03-16 | 宁夏杞肽科技有限公司 | Use of goji glycopeptide in preparation of drug for preventing and/or treating amyotrophic lateral sclerosis |
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| Publication number | Publication date |
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| CN1172699C (en) | 2004-10-27 |
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