CN1213760C - Chinese medicine prepn for treating deficiency of spleen and stomach Yang type atrophic gastritis - Google Patents
Chinese medicine prepn for treating deficiency of spleen and stomach Yang type atrophic gastritis Download PDFInfo
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- CN1213760C CN1213760C CN 02113190 CN02113190A CN1213760C CN 1213760 C CN1213760 C CN 1213760C CN 02113190 CN02113190 CN 02113190 CN 02113190 A CN02113190 A CN 02113190A CN 1213760 C CN1213760 C CN 1213760C
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Abstract
The present invention relates to a traditional Chinese medicine preparation for treating spleen and stomach Yang-deficiency type atrophic gastritis, which belongs to the technical field of compound traditional Chinese medicine preparations. The present invention aims to provide a traditional Chinese medicine preparation for treating spleen and stomach Yang-deficiency type atrophic gastritis, which has the advantages of obvious and stable curative effect and no toxic side effect. The present invention has the technical scheme that raw material comprises the following components by weight percentage of 6 to 12% of radix codonopsitis, 2 to 8% of cassia bark, 1 to 7% of villous amomum fruit, 6 to 12% of psoralea fruit, 6 to 12% of steamed milkvetch root, 4 to 10% of prepared monkshood, 6 to 12% of stir-frying largehead atractylodes rhizome, 8 to 14% of stir-frying hawthorn, 6 to 12% of desertliving cistanche, 6 to 12% of common yan rhizome, 8 to 14% of smoked plum and 4 to 10% of dried tangerine peel; the raw material is prepared into capsules and granules by means of conventional producing processes. The present invention has specific curative effects and obvious effects on treating chronic superficial gastritis and atrophic gastritis, has the advantages of wide clinical application, safety and no toxic side effect, and is ideal new medicine for treating atrophic gastritis with traditional Chinese medicine.
Description
Technical field: the invention belongs to the Chinese medicine complex preparation, particularly a kind of Chinese medicine preparation for the treatment of deficiency of spleen and stomach Yang type atrophic gastritis.
Background technology: atrophic gastritis is a kind of chronic gastritis disease, because the conversion ratio of its gastric cancer is higher, so often be counted as the cercinoma prophase pathologic change of gastric cancer.Therefore, atrophic gastritis is the disease of a kind of serious harm health and safety.According to the theory of the traditional Chinese medical science " dialectical executing controlled, YIN and YANG in a relative equilibrium ", but the atrophic gastritis medicine typing is deficiency of spleen and stomach Yang type and deficiency of spleen and stomach Yin type.The tcm diagnosis standard of deficiency of spleen and stomach Yang type atrophic gastritis is: spleen-stomach deficiency-cold stomachache, vague epigastralgia, happiness temperature pain relieved by pressing, food back feeling of distension and oppression, indigestion and loss of appetite lack of appetite, loose stool, light red tongue or tooth seal, thready pulse are arranged.At present, the medicine that is used for the treatment of chronic gastritis is a lot, as MOLUO DAN, complex stomach spring, SANJIU WEITAI etc., though atrophic gastritis is all had certain curative effect, does not control because it carries out the medicine typing opinion, so be difficult to suit the remedy to the case, therefore, its therapeutic effect is undesirable.Curative effect is not high.
Summary of the invention: technical problem to be solved by this invention is: according to the traditional Chinese medical science " dialectical medication ", the theory of " suiting the remedy to the case ", chronic gastritis is carried out medicine typing opinion control, a kind of Chinese medicine preparation of evident in efficacy, the stable and treatment deficiency of spleen and stomach Yang type atrophic gastritis that has no side effect is provided.Its technical scheme is: a kind of Chinese medicine preparation for the treatment of deficiency of spleen and stomach Yang type atrophic gastritis, it is characterized in that it be following raw materials by weight percent medicine routinely technology make:
Radix Codonopsis 6-12 Cortex Cinnamomi 2-8 Fructus Amomi 1-7 Fructus Psoraleae 6-12
Radix Astragali 6-12 Radix Aconiti Lateralis Preparata 4-10 Rhizoma Atractylodis Macrocephalae (parched) 6-12 Fructus Crataegi (parched) 8-14
Rhizoma Dioscoreae 6-12 Fructus Mume 8-14 Pericarpium Citri Reticulatae 4-10 Herba Cistanches 6-12.
Radix Codonopsis, the Radix Astragali, Rhizoma Dioscoreae, QI invigorating are set upright and are principal agent in the preparation, and the regulating immunological function microcirculation improvement is repaired gastric mucosa, and the atrophy body of gland is had restitution.The Rhizoma Atractylodis Macrocephalae can anti-helicobacter pylori, suppress bile reflux, strengthens the merit of holding up the spleen stomach reinforcing.Fructus Mume, Fructus Crataegi are promoted the production of body fluid aid digestion, two-ways regulation gastric acid secretion function.Cortex Cinnamomi, Herba Cistanches, Radix Aconiti Lateralis Preparata etc. form YANG invigorating side, and are to play spleen kidney complementary action, particularly suitable to advanced age or the prolonged illness kidney qi person of declining.
This preparation is production technology routinely, can make two kinds of dosage forms of capsule and electuary respectively, so that take.
This preparation has the merit of anti-inflammatory and antalgic, warming and invigorating the spleen and stomach, strengthening the body resistance, treating both the principal and secondary aspects of a disease; gastric mucosa and anti-gastric mucosa injury had tangible reparation, protective effect; the gastritis model that freund adjuvant is caused has therapeutical effect preferably; lesion degrees such as gastric mucosal erosion, chronic inflammation cellular infiltration, hyperemia are alleviated or the incidence rate minimizing; alleviate and recover the atrophy of gastric gland body, improve stomach and secrete acid, facilitating digestion liquid and digestive enzyme secretion; strengthen gastric motility, strengthen and recovery immunity.
Through clarifying a diagnosis to deficiency of spleen and stomach Yang type chronic superficial gastritis and atrophic gastritis 60 routine patients to clinical, be divided into two groups at random, take the capsule of this preparation and electuary (its dosage and contain the crude drug amount suitable) respectively.Capsules group 30 examples, wherein atrophic gastritis 17 examples have 9 examples to observe half a year, superficial gastritis 13 examples; The oldest 65 years old, minimum 24 years old; The course of disease is the shortest 1 year, and is the longest 12 years; Electuary group 30 examples, atrophic gastritis 18 examples wherein, have 8 examples to observe half a year, superficial gastritis 12 examples: the oldest 64 years old, minimum 27 years old, the course of disease is the shortest 5 months, and was the longest 10 years.Its symptom total effects sees Table 1.
Table 1
The example number | Produce effects | Effectively | Invalid | Total effective rate (%) | |
Capsules group electuary group | 30 | 7 | 20 | 3 | 90 |
30 | 7 | 19 | 4 | 86.67 |
Its sick curative effect of planting sees Table 2.Table 2
Superficial gastritis | Atrophic gastritis | |||||
Two months | Two months | Six months | ||||
Capsules group | The electuary group | Capsules group | The electuary group | Capsules group | The electuary group | |
The example number | 13 | 12 | 17 | 18 | 9 | 8 |
Produce effects | 6 | 2 | 1 | 4 | 1 | 2 |
Effectively | 6 | 9 | 14 | 11 | 7 | 5 |
Invalid | 1 | 1 | 2 | 3 | 1 | 1 |
Total effective rate (%) | 92.31 | 91.63 | 88.23 | 88.33 | 88.89 | 87.5 |
Its cardinal symptom curative effect sees Table 3.Table 3
The example number | Produce effects | Effectively | Invalid | Total effective rate (%) | ||
Gastralgia | The electuary group | 29 | 14 | 12 | 4 | 86.67 |
Capsules group | 30 | 14 | 14 | 2 | 93.33 | |
Gastral cavity expands | The electuary group | 29 | 14 | 12 | 3 | 89.66 |
Capsules group | 27 | 15 | 9 | 3 | 88.89 | |
The desire for hot drinks aversion to cold and cold limbs | The electuary group | 24 | 10 | 10 | 4 | 83.33 |
Capsules group electuary group | 26 26 | 12 16 | 8 6 | 6 3 | >6.92 84.62 | |
Capsules group | 21 | 7 | 7 | 5 | >6.19 | |
Spiritlessness and weakness | The electuary group | 25 | 13 | 9 | 3 | 88 |
Capsules group | 22 | 10 | 8 | 4 | 81.82 |
Annotate: because of not adhering to bolter's 1 example of taking medicine; Lose visit person's 1 example.
Its gastroscopy effect sees Table 4.Table 4
Superficial gastritis | Atrophic gastritis | |||||
Two months | Six months | |||||
The electuary group | Capsules group | The electuary group | Capsules group | The electuary group | Capsules group | |
The example number | 13 | 12 | 17 | 18 | 9 | 8 |
Produce effects | 4 | 2 | 2 | 3 | 1 | 1 |
Effectively | 7 | 8 | 8 | 9 | 6 | 5 |
Invalid | 2 | 2 | 7 | 6 | 2 | 2 |
Total effective rate (%) | 84.62 | 83.33 | 58.82 | 66.67 | >7.78 | >5 |
Annotate: because it is former thereby reject 2 examples not carry out gastroscopy etc. before and after can not taking medicine on request or treat.
Through clinical observation more than a year, this preparation is not found side effect, and check routine blood test, liver, renal function etc. do not find that it has infringement to important organs such as the blood system heart, liver, kidneys before and after the treatment.Its safety sees that check sees Table 5.
Table 5
The unusual case load of Capsules group | The unusual case load of electuary group | |||
Before the treatment | After the treatment | Before the treatment | After the treatment | |
HB | 0 | 0 | 0 | 0 |
WBC | 0 | 0 | 0 | 0 |
RBC | 0 | 0 | 0 | 0 |
SGPT | 0 | 0 | 0 | 0 |
RUN | 0 | 0 | 0 | 0 |
CR | 0 | 0 | 0 | 0 |
OB | 0 | 0 | 0 | 0 |
Psychology figure | 0 | 0 | 0 | 0 |
In sum, this Chinese medicine preparation, no matter be capsule or electuary, treatment deficiency of yang type chronic superficial gastritis and atrophic gastritis all there are definite curative effect and significant effect, clinical application is extensive, safety, and has no side effect, to its course of treatment of curative effect proper extension of deficiency of yang type atrophic gastritis, more helping to improve curative effect, is the comparatively ideal new drug of treatment by Chinese herbs deficiency of yang type chronic superficial gastritis and atrophic gastritis.
Embodiment:
Embodiment 1: get Radix Codonopsis 6Kg, Rhizoma Dioscoreae 12kg, Radix Astragali 12kg, Cortex Cinnamomi 2kg, Fructus Amomi 1kg, Fructus Psoraleae 6kg, Radix Aconiti Lateralis Preparata 4kg, Fructus Mume 14kg, the Rhizoma Atractylodis Macrocephalae (stir-fry) 16kg, Fructus Crataegi (stir-fry) 8kg, Herba Cistanches 12kg, Pericarpium Citri Reticulatae 4.5kg, production technology is made capsule or electuary dosage form routinely.
Embodiment 2: get Radix Codonopsis 9kg, Rhizoma Dioscoreae 9kg, Radix Astragali 9kg, Cortex Cinnamomi 5kg, Fructus Amomi 4kg, Fructus Psoraleae 9kg, Radix Aconiti Lateralis Preparata 7kg, Pericarpium Citri Reticulatae 8kg, Fructus Mume 11kg, the Rhizoma Atractylodis Macrocephalae (stir-fry) 9kg, Fructus Crataegi 11kg, Herba Cistanches 9kg, production technology is made capsule or electuary dosage form routinely.
Embodiment 3: get Radix Codonopsis 12kg, Rhizoma Dioscoreae 6kg, Radix Astragali 6kg, Cortex Cinnamomi 8kg, Fructus Amomi 7kg, Fructus Psoraleae 12kg, Radix Aconiti Lateralis Preparata 11kg, Fructus Mume 8kg, the Rhizoma Atractylodis Macrocephalae (stir-fry) 12kg, Fructus Crataegi 14kg Herba Cistanches 6kg, Pericarpium Citri Reticulatae 10kg routinely production technology make capsule or electuary dosage form.
Claims (2)
1, a kind of Chinese medicine preparation for the treatment of deficiency of spleen and stomach Yang type atrophic gastritis, it is characterized in that it be following raw materials by weight percent medicine routinely technology make:
Radix Codonopsis 6-12 Cortex Cinnamomi 2-8 Fructus Amomi 1-7 Fructus Psoraleae 6-12
Radix Astragali 6-12 Radix Aconiti Lateralis Preparata 4-10 Rhizoma Atractylodis Macrocephalae (parched) 6-12 Fructus Crataegi (parched) 8-14
Rhizoma Dioscoreae 6-12 Fructus Mume 8-14 Pericarpium Citri Reticulatae 4-10 Herba Cistanches 6-12.
2, a kind of Chinese medicine preparation according to claim 1 is characterized in that described preparation is electuary or two kinds of dosage forms of capsule.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102406905A (en) * | 2011-11-07 | 2012-04-11 | 许从玉 | Medicinal composition for preventing or treating chronic atrophic gastritis and use thereof |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1709497B (en) * | 2005-06-29 | 2010-05-26 | 贵州苗莹药业科技开发有限公司 | Miao-medicine composition and its use |
CN101406599B (en) * | 2008-12-05 | 2010-12-15 | 正大青春宝药业有限公司 | Pharmaceutical composition for treating chronic atrophic gastritis |
CN101698079B (en) * | 2009-11-06 | 2012-05-02 | 合肥神鹿双鹤药业有限责任公司 | Quality test method of Wenweishu granules |
CN102327332B (en) * | 2011-10-12 | 2014-05-07 | 四川农业大学 | Chinese veterinary medicinal composition for treating hypothermia and preparation method for micro-capsule preparations thereof |
CN110339330A (en) * | 2019-07-25 | 2019-10-18 | 河南中医药大学 | A kind of Chewable Tablets of Chinese traditional medicine for treating superficial gastritis |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102406905A (en) * | 2011-11-07 | 2012-04-11 | 许从玉 | Medicinal composition for preventing or treating chronic atrophic gastritis and use thereof |
CN102406905B (en) * | 2011-11-07 | 2012-08-22 | 许从玉 | Medicinal composition for preventing or treating chronic atrophic gastritis and use thereof |
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