CN101062263A - Medicine for treating coronary heart disease - Google Patents
Medicine for treating coronary heart disease Download PDFInfo
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- CN101062263A CN101062263A CNA2007100157489A CN200710015748A CN101062263A CN 101062263 A CN101062263 A CN 101062263A CN A2007100157489 A CNA2007100157489 A CN A2007100157489A CN 200710015748 A CN200710015748 A CN 200710015748A CN 101062263 A CN101062263 A CN 101062263A
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Abstract
The invention discloses a medicament for treating coronary disease which is prepared from the following constituents: Ligusticum wallichii, root of red rooted saliva, peach kernels, radix paeoniae rubrathe, leeches, notoginseng, astragalus root, pilose asiabell root, prepared aconite root, cassia twig, lilyturf root, earthworm, musk and boneol.
Description
Technical field
Medicine of the present invention belongs to pure Chinese medicine micropowder (more than 200 orders) technical field, is the medicine of raw material treatment coronary heart disease specifically with the Chinese herbal medicine
Background technology
The strong atherosclerotic heart disease of coronary heart disease full name hat, be the cardiovascular system commonly encountered diseases, frequently-occurring disease, at present China's sickness rate is in rapid rising, and age of onset is rejuvenation day by day, and the myocardial infarction due to the coronary heart disease has become current invisible killer, many doctors liken coronary heart disease to and are embedded in patient's intravital " Rhizoma Anemones flaccidae ", in case the meaning is that acute myocardial infarction takes place, fatal probability is very big, and visible coronary heart disease does not just have a strong impact on person people's live and work.Therefore concentrating on studies and studying intensively through the more than ten years in person, finally made a kind of medicine for the treatment of coronary heart disease, this medicine is coached by traditional theory of Chinese medical science, and with reference to the viewed pathological change of the advanced scientific method of modern medicine, checking is summed up and formed repeatedly.Clinical use through routine patients with coronary heart disease up to a hundred is observed, medicine of the present invention to coronary heart disease cause uncomfortable in chest, breathe hard, symptom instant effect such as angina pectoris, stable curative effect is definite, without any side effects, can effectively improve the strong arterial blood circulation of hat, reduce viscosity of blood, increase myocardial flow, improve myocardial hypoxia tolerance, strengthen myocardial contraction, softening hardened coronary artery improves myocardial function, reduce treating myocardial ischemia damage, all have remarkable advantages and curative effect.
The object of the present invention is to provide a kind of pure Chinese medicinal preparation for the treatment of coronary heart disease, have activating blood circulation to dissipate blood stasis, QI invigorating eliminating stagnation, inducing diuresis to remove edema, the promoting the circulation of QI the chest stuffiness relieving, fragrance, warming YANG a surname is logical, thereby reaches the purpose of curing coronary heart disease rapidly.
Summary of the invention
Technical scheme of the present invention is based on understanding and the Therapeutic Principle of motherland's traditional medicine to incidence of coronary heart disease mechanism, with reference to modern pharmacological research, select for use removing blood stasis pursue the handsome blood operation of silt, promoting blood circulation, enhancing, temperature logical in the heart yang-energy, resolving fluid-retention with drugs of warm nature, YIN nourishing and the production of body fluid promoting, promoting the circulation of QI the chest stuffiness relieving, activating blood circulation to dissipate blood stasis, invigorate vital energy and reinforce the heart, inducing diuresis to remove edema, sensible, the consciousness and resuscitation restoring class medicine composition of promoting the circulation of QI the chest stuffiness relieving fragrance, but activating blood circulation to dissipate blood stasis, invigorate vital energy and reinforce the heart, inducing diuresis to remove edema, promoting the circulation of QI the chest stuffiness relieving fragrance are led to, and consciousness and resuscitation restoring reaches the purpose of curing coronary heart disease rapidly.
Prescription of the present invention and deal are as follows:
Rhizoma Chuanxiong 100-150, Radix Salviae Miltiorrhizae 130-180, Semen Persicae 80-120, Radix Paeoniae Rubra 80-120, Hirudo 130-180, Radix Notoginseng 80-120, Radix Astragali 130-180, Radix Codonopsis 130-180, Radix Aconiti Lateralis Preparata 20-60, Ramulus Cinnamomi 80-120, Radix Ophiopogonis 80-120, Pheretima 80-120, Fructus Trichosanthis 80-120, the white 80-120 of a round bamboo basket, Moschus 2-6, Borneolum Syntheticum 4-8.
Prescription of the present invention and optimum feed stock deal are:
Rhizoma Chuanxiong 120, Radix Salviae Miltiorrhizae 150, Semen Persicae 100, Radix Paeoniae Rubra 100, Hirudo 150, Radix Notoginseng 100, the Radix Astragali 150, Radix Codonopsis 150, Radix Aconiti Lateralis Preparata 45, Ramulus Cinnamomi 100, Radix Ophiopogonis 100, Pheretima 100, Fructus Trichosanthis 100, a round bamboo basket are white 100, Moschus 4, Borneolum Syntheticum 6.
Use said medicine of the present invention, treatment coronary heart disease curative effect is obvious, and it is rapid, easy to use to remove coronary heart disease symptom, nontoxic pair and stimulation, effective percentage 83.4%, cure rate 43.3%.
The mechanism of medicine of the present invention is as follows:
Rhizoma Chuanxiong: meridian distribution of property and flavor: suffering, temperature.Return liver and gall, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping is seen high medical college teaching material " Chinese materia medica ", Shanghai science tech publishing house publishes, the 17th printing in May nineteen fifty-five, chief editor: insult a principle, associate editor: Yan Zhenghua (seeing 140 pages)
Radix Salviae Miltiorrhizae: meridian distribution of property and flavor: hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Effect: activating blood and removing stasis, loosening bowel to relieve constipation.(the same, see 154 pages)
Semen Persicae: meridian distribution of property and flavor: hardship, sweet, flat.Slightly poisonous GUIXIN, liver, large intestine channel.Effect: activating blood and removing stasis, loosening bowel to relieve constipation.(the same, as to see 157 pages)
Radix Paeoniae Rubra: meridian distribution of property and flavor: hardship is slightly cold.Return Liver Channel.Effect: clearing away heat and cooling blood, the silt pain relieving of dispelling.(the same, see 47 pages)
Hirudo: meridian distribution of property and flavor: salty, bitter, flat, slightly poisonous.Return Liver Channel.Effect: removing blood stasis is by becoming silted up.(the same, as to see 162 pages)
Radix Notoginseng: meridian distribution of property and flavor: sweet, little hardship, temperature.Return liver, the stomach warp.Effect: change the silt hemostasis, the analgesic therapy of invigorating blood circulation.(the same, as to see 144 pages)
The Radix Astragali: meridian distribution of property and flavor: sweet, tepor.Return spleen, lung meridian.Effect: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, inducing diuresis to remove edema.(the same, as to see 212 pages)
Radix Codonopsis: meridian distribution of property and flavor: sweet, flat.Return spleen, lung meridian.Effect: invigorating the spleen and replenishing QI, promote the production of body fluid and nourish blood.(the same, as to see 211 pages)
Radix Aconiti Lateralis Preparata: meridian distribution of property and flavor: suffering, heat, poisonous.GUIXIN, kidney, spleen channel.Effect: recuperating depleted YANG and rescuing the patient from collapse, it is supporing yang to mend fire, dispersing cold for relieving pain.(the same, see 108 pages)
Ramulus Cinnamomi: meridian distribution of property and flavor: suffering, sweet, temperature.GUIXIN, lung, urinary bladder channel.Effect: send out the Chinese and induce sweat warming the meridian for promoting the flow of YANG QI.(the same, as to see 17 pages)
Radix Ophiopogonis: meridian distribution of property and flavor: sweet, little hardship, cold.Return lung, the heart, stomach warp.Effect: nourishing lung-YIN, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.(the same, as to see 237 pages)
Pheretima: meridian distribution of property and flavor: salty, cold.Return liver, spleen, urinary bladder channel.Effect: clearing heat for calming endogenous wind, relieving asthma collateral dredging, diuresis.(the same, as to see 203 pages)
Fructus Trichosanthis: meridian distribution of property and flavor: sweet, cold.Return lung, stomach, large intestine channel.Effect: removing heat from the lung and dissipating phlegm, promoting the circulation of QI the chest stuffiness relieving.(the same, as to see 174 pages)
Moschus: meridian distribution of property and flavor: suffering, temperature.GUIXIN, spleen channel.Effect: the refreshment of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, pain relieving is hastened parturition.(the same, as to see 205 pages)
Borneolum Syntheticum: meridian distribution of property and flavor: suffering, hardship is slightly cold.GUIXIN, spleen, lung meridian.Effect: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.(the same, as to see 206 pages)
A round bamboo basket is white: meridian distribution of property and flavor: suffering, hardship, temperature.Return lung, stomach, large intestine channel.Effect: activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.See " middle hospital pharmacy ", the Guangdong college of traditional Chinese medicine writes, and the Guangdong People's Press publishes, the first impression in June, 1973.(seeing 491 pages)
Chinese medicine thinks that coronary heart disease belongs to the traditional Chinese medical science thoracic obstruction, the obstruction of heart-QI, angina pectoris category.Primary disease is the qi stagnation blood stasis stagnation of QI and blood may bring about pain, and what it was obstructed causes because of mostly being the stagnation of QI, blood stasis, cold coagulation, stagnation of phlegm etc.Pathogenesis is the disease of deficiency in origin and excess in superficiality, and this its void hot in nature of the heart must be trembled with fear, and cold coagulation heart network is obstructed to the bloody path obturation, and that disease is seen is uncomfortable in chest, breathe hard, angina pectoris.By becoming silted up, promoting blood circulation is dispeled the stasis of heart network with Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra, Hirudo, Radix Notoginseng removing blood stasis in the present invention; The Radix Astragali, Radix Codonopsis invigorate vital energy and reinforce the heart, and strengthen the ability of handsome blood operation; Radix Aconiti Lateralis Preparata, the logical yang-energy in the heart of Ramulus Cinnamomi temperature, resolving fluid-retention with drugs of warm nature; Radix Ophiopogonis, YIN nourishing and the production of body fluid promoting made Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi temperature and not dry; The diuresis of Pheretima collateral dredging makes the heresy of diseases caused by retention of fluid separate from urine; Fructus Trichosanthis, a round bamboo basket Brix gas the chest stuffiness relieving can be dispeled the stagnation of phlegm of heart network; All medicines share and play activating blood circulation to dissipate blood stasis altogether, invigorate vital energy and reinforce the heart, inducing diuresis to remove edema, the merit of promoting the circulation of QI the chest stuffiness relieving; Add Moschus, Borneolum Syntheticum fragrance is sensible, consciousness and resuscitation restoring draws all medicines and goes into heart channel and heighten the effect of a treatment and reach the purpose of curing coronary heart disease rapidly.
The specific embodiment
The invention will be further described below in conjunction with embodiment.
Embodiment: get that Rhizoma Chuanxiong 120, Radix Salviae Miltiorrhizae 150, Semen Persicae 100, Chinese herbaceous peony 100, Hirudo 150, Radix Notoginseng 100, the Radix Astragali 150, Radix Codonopsis 150, Radix Aconiti Lateralis Preparata 45, Ramulus Cinnamomi 100, Radix Ophiopogonis 100, Pheretima 100, Fructus Trichosanthis 100, a round bamboo basket are white 100, Moschus 4, Borneolum Syntheticum 6.Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Semen Persicae, Radix Paeoniae Rubra, Hirudo, Radix Notoginseng, the Radix Astragali, Radix Codonopsis, Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, Radix Ophiopogonis, Pheretima, Fructus Trichosanthis, white 14 herbal medicines of a round bamboo basket are made micropowder (200 order), then Moschus, Borneolum Syntheticum are ground into fine powder with grinding bowl, standby Moschus, Borneolum Syntheticum and the abundant mix homogeneously of preceding 14 flavor Chinese medicine micropowders.A 6-9 gram 3 times on the one, soaks 15 minutes clothes with certain amount of boiling water with medicated powder after meal.
For showing curative effect of medication of the present invention, divide matched group and the test group shelves of existing side by side to stay to examine and add up contrast: matched group oral administered compound Radix Salviae Miltiorrhizae drop pill, obey 10 at every turn, every day 3 (production of sky, Tianjin Shi Li drugmaker, lot numbers: 040615).Test group medicine of the present invention, a 6-9 gram 3 times on the one, soaks 15 minutes clothes with certain amount of boiling water with medicated powder after meal.Two groups are all treated 2 months was 1 course of treatment, totally 3 courses of treatment.Since two thousand three,, carried out the clinical efficacy contrast, included 120 routine patients altogether in FUFANG DANSHEN DIWAN for determining the curative effect and the advantage of this medicine.Ratio was distributed by 1: 1, forbade other drug during two groups of treatments.
Clinical data
Diagnostic criteria: with reference to the treatment thoracic obstruction (angina pectoris) standard formulation in " new Chinese medicine clinical research guideline ".Suffocating pain over the chest, even chest pain radiating to the back, that the lighter tightly feels is uncomfortable in chest, feel suffocated, hypopnea.
MethodsThe cases enrolled: include case in and be age 25-75 year, have typical thoracic obstruction primary symptom, meet the tcm diagnosis standard, medical history more than 6 months is arranged, the out-patient who is ready and can adheres to treating.Selected case is assigned as two groups of test group and matched groups, test group (taking medicine group of the present invention); Matched group (taking Composite Salvia Dropping Pill group).Test group male's 36 examples, women's 24 examples, year mean age (56.30 ± 6.8), body weight (61.5 ± 8.9) kg, individual month of medical history (62.5 ± 45.7); Matched group male 29 examples, women's 31 examples, year mean age (59.6 ± 6.1), body weight (57.3 ± 9.2) kg, individual month of medical history (60.1 ± 39.5).Not having significant difference aspect sex, age, the course of disease, the state of an illness, has comparability between two groups.
Observation index: health giving quality observation respectively at test before, following project is observed in 2nd month, test back in the test: (1) clinical symptoms: chest pain, uncomfortable in chest, cardiopalmus, breathe hard the frequency of angina pectoris attacks, position, persistent period, pain degree etc.(2) sign: picture of the tongue and pulse condition change.(3) objective observation: electrocardiogram, ambulatory electrocardiogram, exercise stress test.
Criterion of therapeutical effect: (1) clinic control: chest pain, uncomfortable in chest, the transference cure of breathing hard are for curing.(2) produce effects: chest pain, uncomfortable in chest, breathe hard disappearance or basic the disappearance.(3) effective: the chest pain outbreak obviously reduces, uncomfortable in chest, breathing hard obviously alleviates.(4) invalid: chest pain, uncomfortable in chest, the symptom of breathing hard do not have improvement.
Therapeutic outcome: test group clinic control 26 examples (43.3%), produce effects 15 examples (25%), effective 9 examples (15%), invalid 10 examples (16,6%), total effective rate 83.4%, cure rate 43.3%.Matched group clinic control 19 examples (31.6%), produce effects 22 examples (36.6%), effective 5 examples (8.3%), invalid 14 examples (23.3%), total effective rate 76.7%, cure rate 30%.
By above clinical trial preliminary identification the effectiveness of Drug therapy coronary heart disease of the present invention, symptom such as this medicine can effectively improve chest pain that coronary heart disease causes, uncomfortable in chest, cardiopalmus, breathe hard, curative effect is better than FUFANG DANSHEN DIWAN.
Claims (2)
1, a kind of medicine for the treatment of coronary heart disease, it is characterized in that: it is the medicine that the deal by following raw material of Chinese medicine prescription proportioning is made, Rhizoma Chuanxiong 100-150, Radix Salviae Miltiorrhizae 130-180, Semen Persicae 80-120, Radix Paeoniae Rubra 80-120, Hirudo 130-180, Radix Notoginseng 80-120, Radix Astragali 130-180, Radix Codonopsis 130-180, Radix Aconiti Lateralis Preparata 20-60, Ramulus Cinnamomi 80-120, Radix Ophiopogonis 80-120, Pheretima 80-120, Fructus Trichosanthis 80-120, the white 80-120 of a round bamboo basket, Moschus 2-6, Borneolum Syntheticum 4-8.
2, a kind of medicine for the treatment of coronary heart disease according to claim 1, it is characterized in that: it is the medicine that the deal by following raw material of Chinese medicine prescription proportioning is made, and Rhizoma Chuanxiong 120, Radix Salviae Miltiorrhizae 150, Semen Persicae 100, Radix Paeoniae Rubra 100, Hirudo 150, Radix Notoginseng 100, the Radix Astragali 150, Radix Codonopsis 150, Radix Aconiti Lateralis Preparata 45, Ramulus Cinnamomi 100, Radix Ophiopogonis 100, Pheretima 100, Fructus Trichosanthis 100, a round bamboo basket are white 100, Moschus 4, Borneolum Syntheticum 6.
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CNA2007100157489A CN101062263A (en) | 2007-05-18 | 2007-05-18 | Medicine for treating coronary heart disease |
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CNA2007100157489A CN101062263A (en) | 2007-05-18 | 2007-05-18 | Medicine for treating coronary heart disease |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102631655A (en) * | 2012-04-05 | 2012-08-15 | 徐学军 | Medicine for treating coronary heart disease and preparation method for medicine |
CN102631538A (en) * | 2012-04-20 | 2012-08-15 | 蔡惠磊 | Traditional Chinese medicine for treating heart disease |
CN102872455A (en) * | 2012-09-28 | 2013-01-16 | 贵阳中医学院 | Medicament for preventing in-stent restenosis after coronary stent implantation and preparation method |
CN104208416A (en) * | 2014-08-16 | 2014-12-17 | 济南伟传信息技术有限公司 | Traditional Chinese medicine for treatment of myocardial infarction |
CN104840739A (en) * | 2015-05-25 | 2015-08-19 | 闫明昌 | Traditional Chinese medicine composition for treating coronary heart disease |
-
2007
- 2007-05-18 CN CNA2007100157489A patent/CN101062263A/en active Pending
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102631655A (en) * | 2012-04-05 | 2012-08-15 | 徐学军 | Medicine for treating coronary heart disease and preparation method for medicine |
CN102631655B (en) * | 2012-04-05 | 2013-10-30 | 徐学军 | Medicine for treating coronary heart disease and preparation method for medicine |
CN102631538A (en) * | 2012-04-20 | 2012-08-15 | 蔡惠磊 | Traditional Chinese medicine for treating heart disease |
CN102631538B (en) * | 2012-04-20 | 2014-01-15 | 蔡惠磊 | Traditional Chinese medicine for treating heart disease |
CN102872455A (en) * | 2012-09-28 | 2013-01-16 | 贵阳中医学院 | Medicament for preventing in-stent restenosis after coronary stent implantation and preparation method |
CN104208416A (en) * | 2014-08-16 | 2014-12-17 | 济南伟传信息技术有限公司 | Traditional Chinese medicine for treatment of myocardial infarction |
CN104840739A (en) * | 2015-05-25 | 2015-08-19 | 闫明昌 | Traditional Chinese medicine composition for treating coronary heart disease |
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