CN101569708B - Medicament for treating ischemic heart disease and preparation method thereof - Google Patents

Medicament for treating ischemic heart disease and preparation method thereof Download PDF

Info

Publication number
CN101569708B
CN101569708B CN2008100496707A CN200810049670A CN101569708B CN 101569708 B CN101569708 B CN 101569708B CN 2008100496707 A CN2008100496707 A CN 2008100496707A CN 200810049670 A CN200810049670 A CN 200810049670A CN 101569708 B CN101569708 B CN 101569708B
Authority
CN
China
Prior art keywords
radix
medicine
ischemic heart
heart desease
atractylodis macrocephalae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2008100496707A
Other languages
Chinese (zh)
Other versions
CN101569708A (en
Inventor
孟凡香
徐泽明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN2008100496707A priority Critical patent/CN101569708B/en
Publication of CN101569708A publication Critical patent/CN101569708A/en
Application granted granted Critical
Publication of CN101569708B publication Critical patent/CN101569708B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention discloses a medicament for treating ischemic heart disease. The medicament comprises the following ingredients by weight percentage: 20 to 30 of astragalus, 20 to 30 of hawthorn pulp, 15to 20 of red sage roots, 8 to 10 of polygonum capitatum, 2 to 5 of panax notoginseng, 8 to 10 of cinnamon core, 8 to 10 of white peony roots, 8 to 10 of spine date seeds, 2 to 5 of hungry roots, 10 t o 20 of lanceolata, 2 to 5 of macrostem onion, 2 to 5 of trichosanthes fruit and 2 to 5 of atractylodes. The medicament has the functions of promoting the blood circulation, stimulating the endocrine and the digestive absorption of the spleen and the stomach, improving the myocardial blood supply, increasing the coronary blood flow, reducing the myocardial oxygen consumption, clearing the mind, calming the nerves, adjusting the yin and yang equilibrium of the viscera and treating both principal and secondary aspects of the disease.

Description

A kind of medicine for the treatment of ischemic heart desease and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of ischemic heart desease, being specifically related to a kind of is the Chinese medicine composition of raw material with the Chinese herbal medicine, the invention still further relates to the preparation method of this medicine.
Background technology
Ischemic heart desease such as coronary heart disease, myocardial infarction, angina pectoris, arrhythmia etc. are big persistent ailments that threatens world's healthy population.Along with the raising of people's living standard, the modern overworks, and mental pressure is excessive, does not note rationally arranging diet at ordinary times again, the living habit of not forming, and the essential motion of less participation, and the sickness rate of ischemic heart desease rises day by day.
Clinical application has nitroglycerin, Riboflavin Tetrabutyrate, loves medicines such as fixed in the Western medicine of cardiovascular disease in recent years, and its therapeutic effect is also better.But chemical drugs generally is used for acute patient more, and certain side effect is arranged.Aspect Chinese patent medicine, some are common, and to be used for the medicine such as the curative effects such as Radix Salviae Miltiorrhizae Tabellae, FUFANG DANSHEN PIAN of chronic ischemic heart disease limited; Be used for the clinical pills for curing heart disease that has immediate effect of heart acute disease, Styrax Pilulae, the main armaticity medical material that uses of this class medicine composition, have happy key, the effect of the mind of waking up, instant effect, effect is also better, but its effect is of short duration, is not suitable for the chronic heart disease patient and uses; New drug in recent years is used for clinical in DIAOXINXUE KANG, haydan capsule, heart treasured etc., and rare precious animals and plants such as toad Moschus moschiferous are arranged in the prescription of these medicines, costs an arm and a leg, and its curative effect is also not fully up to expectations.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, a kind of medicine for the treatment of ischemic heart desease and preparation method thereof is provided.
The objective of the invention is to be achieved through the following technical solutions:
The medicine of treatment ischemic heart desease of the present invention, form by following component by weight:
Radix Astragali 30~20 Fructus Crataegi 30~20
Radix Salviae Miltiorrhizae 20~15 Radixs Polygoni Multiflori 10~8
Radix Notoginseng 5~2 Cortex Cinnamomi 10~8
The Radix Paeoniae Alba 10~8 Semen Ziziphi Spinosaes 10~8
Radix Et Rhizoma Nardostachyos 5~2 Radix Codonopsis 20~10
Bulbus Allii Macrostemonis 5~2 trichosanthes fruits 5~2
The Rhizoma Atractylodis Macrocephalae 5~2.
Radix Astragali described in the medicine of the present invention is preferably Inner Mongolia Radix Astragali, described Fructus Crataegi is preferably Beishan Mountain Fructus Crataegi, described Radix Salviae Miltiorrhizae is preferably wild Radix Salviae Miltiorrhizae, the described Radix Polygoni Multiflori is preferably Yunnan-Guizhou Radix Polygoni Multiflori Preparata, described Radix Notoginseng is preferably the Yunnan Typhonium flagelliforme (Lodd.) Blume, the described Radix Paeoniae Alba is preferably Radix Paeoniae Alba, and described Radix Codonopsis is preferably wild codonopsis, and the described Rhizoma Atractylodis Macrocephalae is preferably the Zhejiang Rhizoma Atractylodis Macrocephalae.
The preparation method of the medicine of treatment ischemic heart desease is for to be: respectively Radix Astragali, Fructus Crataegi, Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 65~75 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1~1.2 times of medical material fine powder gross weight, every ball 9 grams.
The usage of medicine of the present invention: once-a-day, one time 3 ball (the serious symptom chronic heart failure can respectively be obeyed two balls sooner or later).
Technical scheme of the present invention belongs to the obstruction of heart-QI disease of Chinese medicine based on ischemic heart desease, and it is profound to belong to weakened YANG QI the moon, the YIN pathogen upper harassing syndrome, and blood stasis due to qi deficiency, blood follows not smooth, function of blood circulating system disappearance degree.The necessary benefiting QI for activating blood circulation trace of treatment, bar reaches mechanism of qi, unimpeded blood source.
Radix Astragali in the side: sweet, tepor.Day spleen lung meridian.The QI invigorating pudendum benefits consolidating superficial resistance, inducing diuresis to remove edema.Fructus Crataegi: acid is sweet little wet.Return spleen, stomach, Liver Channel.Promoting digestion and removing stagnation, the circulation of qi promoting dissipating blood stasis.Radix Salviae Miltiorrhizae: hardship is slightly cold.GUIXIN, Liver Channel.Promoting blood flow to regulate menstruation, removing heat from blood disappear bitterly, calm the nerves.The Radix Polygoni Multiflori: sweet, puckery, little wet.Return liver, kidney channel, heart channel.Enrich and benefit essence and blood, black palpus reinforces the kidney.Radix Notoginseng: sweet, little hardship, temperature.Return liver, the stomach warp.Removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation.Cortex Cinnamomi: suffering, sweet, heat.Return spleen, kidney, the heart, Liver Channel.It is supporing yang to mend fire, dispersing cold for relieving pain, warming the meridian and promoting blood circulation.The Radix Paeoniae Alba: hardship, acid is slightly cold.Return liver, spleen channel.Nourishing blood for regulating menstruation, suppressing the hyperactive liver pain relieving, astringing YIN to stop sweating.Semen Ziziphi Spinosae: sweet, acid, flat.GUIXIN, liver, gallbladder meridian.The liver benefiting that nourishes heart is calmed the nerves arresting sweating.Radix Et Rhizoma Nardostachyos: suffering, sweet, temperature.Return spleen, the stomach warp.Promoting the circulation of QI to relieve pain, relieving stagnation and activating the spleen.Radix Codonopsis: sweet, flat.Return spleen, lung meridian.QI invigorating is promoted the production of body fluid, and nourishes blood.Bulbus Allii Macrostemonis: suffering, hardship, temperature.GUIXIN, lung meridian.Regulate the flow of vital energy, alleviating distention in middle-JIAO activates yang, eliminating stagnation.Thoracic obstruction twinge.Fructus Trichosanthis: sweet, hardship, cold.Return lung, large intestine channel.The thoracic obstruction, constipation.The Rhizoma Atractylodis Macrocephalae: hardship, sweet, temperature.Return spleen, the stomach warp.Air making-up and spleen enlivening, the dampness diuretic.Mel: sweet, flat.Return lung, spleen, large intestine.Really strengthen the spleen and stomach nourishing the lung to arrest cough, laxation relieving constipation, slow middle pain relieving, detoxifcation.
Clinical drug of the present invention uses the result to show that this medicine has following advantage:
Have benefit and live, increase endocrine, impel taste to digest and assimilate, improve blood supply of cardiac muscle, strengthen coronary flow, reduce myocardial oxygen consumption, mind tranquilizing and the heart calming, and the function of regulating internal organs equilibrium between yin and yang and treating both the principal and secondary aspects of a disease is arranged.Medicine of the present invention need not to decoct taking convenience.
For showing medicine of the present invention to ischemic therapeutic effect, with the DIAOXINXUE KANG contrast, the clinical observation result of the present invention being treated ischemic heart desease is as follows.
1. observing time: in February, 1997-2008 year February.
2. clinical data
Among the 189 routine patients, male's 102 examples, women's 87 examples.The oldest 88 years old, minimum 34 years old of age, 61 years old mean age, wherein 34 years old-50 years old 34 examples, 51 years old-60 years old 48 examples, 61 years old-88 years old 107 examples.Type of deficiency of both QI and YIN wherein, myocardial ischemia 87 examples; Coronary heart disease, angina pectoris 54 examples; Hypertension, diabetes 48 examples.The sick 1 year time of bob, maximum duration 12 years, average 6.5 years.All cases are divided equally two groups and are carried out clinical observation, take glad ball 95 examples of heart and brain, take DIAOXINXUE KANG 94 examples, and two groups at the age, sex, and the course of disease, aspects such as clinical setting all have comparability, and through ambulatory electrocardiogram, electrocardio Doppler checks and is foundation.
3. the Therapeutic Method and the course of treatment
The treatment group: take medicine of the present invention, prepare requirement according to pill in appendix 1 rules of preparations of 2001 Pharmacopoeia of People's Republic of China versions and make honeyed pill, every ball 9 grams, ante cibum, sky was obeyed, once-a-day, and each 3 balls, taking medicine continuously 30 days is a course of treatment.
Matched group: take DIAOXINXUE KANG, produce lot number by Chengdu Diao Pharmaceutical Group Co., Ltd: the accurate word of traditional Chinese medicines (Z1090051), every 100mg, each oral 200mg, serve on 30 days one courses of treatment at every day three times.
Two groups of period in a medicine can carry out anti symptom treatment at patient's complication, can give the depressor treatment as the hyperpietic, and the concurrent infection person gives antibiotic therapy, but need not any other treatment ischemic heart desease Chinese and western drugs.
4. observational technique
Cardiovascular system sings and symptoms: check itemized record respectively at before the treatment and the back 30 days ends of taking medicine.
Electrocardio Doppler detects: blood supply changes before and after observing medication.
Electrocardio Doppler checks: observe medication front and back electrocardio, situation of change.
Blood pressure detects: observe medication front and back blood pressure situation.
5. result evaluation
Evaluate according to " the clinical research guideline of new Chinese medicine treatment ischemic heart desease " Chinese medicine criterion of therapeutical effect that Ministry of Health of the People's Republic of China formulates calendar year 2001.Full marks are 29 minutes before treating, and starting point is divided minimum being not less than 17 fens, and its treatment is imitated to evaluate and adopted DIAOXINXUE KANG method (the preceding integration of (integration before the treatment-treatment integration) ÷ treatment) * 100%, represents with percent.(1) basic blood supply improves 〉=86%; (2) produce effects 54%, effectively 〉=35%; Invalid 5%.
6. therapeutic outcome
95 examples are organized in treatment, type of deficiency of both QI and YIN wherein, myocardial ischemia 44 examples, effective 20 examples (45.5%), produce effects 22 examples (50%), invalid 2 examples (4.5%).Coronary heart disease, angina pectoris 27 examples, effective 13 examples (48.1%), produce effects 13 examples (48.1%), invalid 1 example (3.8%).Hypertension, diabetes 24 examples, effective 10 examples (41.7%), produce effects 12 examples (50%), invalid 2 examples (8.3%).
Matched group 94 examples, type of deficiency of both QI and YIN wherein, myocardial ischemia 43 examples, effective 19 examples (44.2%), produce effects 20 examples (46.5%), invalid 5 examples (9.3%).Coronary heart disease, angina pectoris 27 examples, effective 12 examples (44.4%), produce effects 10 examples (37%), invalid 5 examples (18.6%).Hypertension, diabetes 24 examples, effective 11 examples (45.8%), produce effects 10 examples (41.7%), invalid 3 examples (12.5%).
Clinical use result shows, compares medicine of the present invention with matched group and has the following advantages: (1) is good to the treatment and the comprehensive function recovery effects of cardiovascular system symptom.The total effective rate that medicine of the present invention is organized 95 routine patients to treatment is 95%; DIAOXINXUE KANG JIAONANG is 86% to 94 patients' total effective rate.(2) Chinese medical discrimination classification therapy benefiting QI for activating blood circulation, digestion promoting absorbs, and improves the blood supply of cardiac muscle effect and obviously is better than DIAOXINXUE KANG JIAONANG.Observe proof medicine benefiting QI for activating blood circulation of the present invention, removing obstruction in the collateral to relieve pain is promoted diet, improves dyspnea, and is tired out, optimum Ischemic Heart patient.(3) medicine of the present invention has reduction and stabilizing blood pressure to combining the disease hypertensive patient simultaneously, blood fat reducing, and the cholesterol effect is a kind of the have ischemic of controlling disease of ZANG-organs etc., Chinese patent medicine of Comprehensive Treatment effect.
The specific embodiment
Below in conjunction with the specific embodiment the present invention is elaborated.
Embodiment 1
Take by weighing raw material by following proportioning:
Radix Astragali 30 weight portion Fructus Crataegi 15 weight portions
The Radix Salviae Miltiorrhizae 15 weight portion Radixs Polygoni Multiflori 8 weight portions
Radix Notoginseng 3 weight portion Cortex Cinnamomi 8 weight portions
The Radix Paeoniae Alba 10 weight portion Semen Ziziphi Spinosaes 8 weight portions
Radix Et Rhizoma Nardostachyos 3 weight portion Radix Codonopsis 15 weight portions
Bulbus Allii Macrostemonis 2 weight portion trichosanthes fruits 3 weight portions
The Rhizoma Atractylodis Macrocephalae 5 weight portions.
Preparation method is as follows:
Respectively Radix Astragali, Fructus Crataegi, Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 65 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1 times of medical material fine powder gross weight, every ball 9 grams.
Instructions of taking: once-a-day, one time 3 ball.
Embodiment 2
Take by weighing raw material by following proportioning:
Inner Mongolia Radix Astragali 28 weight portion Fructus Crataegi 28 weight portions
The Radix Salviae Miltiorrhizae 16 weight portion Radixs Polygoni Multiflori 8.5 weight portions
Radix Notoginseng 4 weight portion Cortex Cinnamomi 8.5 weight portions
The Radix Paeoniae Alba 9.5 weight portion Semen Ziziphi Spinosaes 8.5 weight portions
Radix Et Rhizoma Nardostachyos 2 weight portion Radix Codonopsis 12 weight portions
Bulbus Allii Macrostemonis 3 weight portion trichosanthes fruits 4 weight portions
The Rhizoma Atractylodis Macrocephalae 4 weight portions.
Preparation method is as follows:
Respectively Inner Mongolia Radix Astragali, Fructus Crataegi, Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 70 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1.2 times of medical material fine powder gross weights, every ball 9 grams.
Instructions of taking: once-a-day, one time 3 ball.
Embodiment 3
Take by weighing raw material by following proportioning:
Radix Astragali 25 weight portion Beishan Mountain Fructus Crataegi 23 weight portions
The Radix Salviae Miltiorrhizae 18 weight portion Radixs Polygoni Multiflori 9 weight portions
Radix Notoginseng 5 weight portion Cortex Cinnamomi 9 weight portions
The Radix Paeoniae Alba 9 weight portion Semen Ziziphi Spinosaes 9 weight portions
Radix Et Rhizoma Nardostachyos 4 weight portion Radix Codonopsis 10 weight portions
Bulbus Allii Macrostemonis 4 weight portion trichosanthes fruits 3.5 weight portions
The Rhizoma Atractylodis Macrocephalae 3 weight portions.
Preparation method is as follows:
Respectively Radix Astragali, Beishan Mountain Fructus Crataegi, Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 70 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1.2 times of medical material fine powder gross weights, every ball 9 grams.
Instructions of taking: once-a-day, one time 3 ball.
Embodiment 4
Take by weighing raw material by following proportioning:
Inner Mongolia Radix Astragali 23 weight portion Fructus Crataegi 20 weight portions
The wild Radix Salviae Miltiorrhizae 19 weight portion Radixs Polygoni Multiflori 9.5 weight portions
Radix Notoginseng 2 weight portion Cortex Cinnamomi 10 weight portions
The Radix Paeoniae Alba 8.5 weight portion Semen Ziziphi Spinosaes 9.5 weight portions
Radix Et Rhizoma Nardostachyos 5 weight portion Radix Codonopsis 18 weight portions
Bulbus Allii Macrostemonis 5 weight portion trichosanthes fruits 2 weight portions
The Rhizoma Atractylodis Macrocephalae 2 weight portions.
Preparation method is as follows:
Respectively Inner Mongolia Radix Astragali, Fructus Crataegi, wild Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 75 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1.2 times of medical material fine powder gross weights, every ball 9 grams.
Instructions of taking: once-a-day, one time 3 ball.
Embodiment 5
Take by weighing raw material by following proportioning:
Radix Astragali 20 weight portion Beishan Mountain Fructus Crataegi 30 weight portions
The wild Radix Salviae Miltiorrhizae 20 weight portion Radixs Polygoni Multiflori 10 weight portions
Radix Notoginseng 2.5 weight portion Cortex Cinnamomi 9.5 weight portions
The Radix Paeoniae Alba 8 weight portion Semen Ziziphi Spinosaes 10 weight portions
Radix Et Rhizoma Nardostachyos 3.5 weight portion Radix Codonopsis 20 weight portions
Bulbus Allii Macrostemonis 3.5 weight portion trichosanthes fruits 5 weight portions
The Rhizoma Atractylodis Macrocephalae 2.5 weight portions.
Preparation method is as follows:
Respectively Radix Astragali, Beishan Mountain Fructus Crataegi, wild Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 70 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1.2 times of medical material fine powder gross weights, every ball 9 grams.
Instructions of taking: once-a-day, one time 3 ball.
Embodiment 6
Repeat the preparation method of embodiment 3, except that used Radix Salviae Miltiorrhizae was wild Radix Salviae Miltiorrhizae, other medicines were identical with embodiment 3, and each amount of drug is also identical with embodiment 3.
Embodiment 7
Repeat the preparation method of embodiment 1, except that the used Radix Polygoni Multiflori was Yunnan-Guizhou Radix Polygoni Multiflori Preparata, other medicines were identical with embodiment 1, and each amount of drug is also identical with embodiment 1.
Embodiment 8
Repeat the preparation method of embodiment 2, except that the used Radix Polygoni Multiflori was Yunnan-Guizhou Radix Polygoni Multiflori Preparata, other medicines were identical with embodiment 2, and each amount of drug is also identical with embodiment 2.
Embodiment 9
Repeat the preparation method of embodiment 6, except that the used Radix Polygoni Multiflori was Yunnan-Guizhou Radix Polygoni Multiflori Preparata, other medicines were identical with embodiment 6, and each amount of drug is also identical with embodiment 2.
Embodiment 10
Repeat the preparation method of embodiment 1, removing used Radix Notoginseng is the Yunnan Typhonium flagelliforme (Lodd.) Blume, and the used Radix Paeoniae Alba is a Radix Paeoniae Alba, and used Radix Codonopsis is a wild codonopsis, and the used Rhizoma Atractylodis Macrocephalae is outside the Rhizoma Atractylodis Macrocephalae of Zhejiang, and other medicines are identical with embodiment 1, and each amount of drug is also identical with embodiment 1.
Embodiment 11
Repeat the preparation method of embodiment 2, removing used Radix Notoginseng is the Yunnan Typhonium flagelliforme (Lodd.) Blume, and the used Radix Paeoniae Alba is a Radix Paeoniae Alba, and used Radix Codonopsis is a wild codonopsis, and the used Rhizoma Atractylodis Macrocephalae is outside the Rhizoma Atractylodis Macrocephalae of Zhejiang, and other medicines are identical with embodiment 2, and each amount of drug is also identical with embodiment 2.
Embodiment 12
Repeat the preparation method of embodiment 6, removing described is the Yunnan Typhonium flagelliforme (Lodd.) Blume with Radix Notoginseng, and the used Radix Paeoniae Alba is a Radix Paeoniae Alba, and used Radix Codonopsis is a wild codonopsis, and the used Rhizoma Atractylodis Macrocephalae is outside the Rhizoma Atractylodis Macrocephalae of Zhejiang, and other medicines are identical with embodiment 6, and each amount of drug is also identical with embodiment 6.
Weight portion in the foregoing description can be gram, kilogram or other unit of weight.
Medicine of the present invention also can decoct jointly to be made decoction and takes for the patient.

Claims (10)

1. medicine for the treatment of ischemic heart desease is characterized in that it is made up of following component by weight:
Radix Astragali 30~20 Fructus Crataegi 30~20
Radix Salviae Miltiorrhizae 20~15 Radixs Polygoni Multiflori 10~8
Radix Notoginseng 5~2 Cortex Cinnamomi 10~8
The Radix Paeoniae Alba 10~8 Semen Ziziphi Spinosaes 10~8
Radix Et Rhizoma Nardostachyos 5~2 Radix Codonopsis 20~10
Bulbus Allii Macrostemonis 5~2 trichosanthes fruits 5~2
The Rhizoma Atractylodis Macrocephalae 5~2.
2. the medicine of treatment ischemic heart desease according to claim 1 is characterized in that: described Radix Astragali is an Inner Mongolia Radix Astragali.
3. the medicine of treatment ischemic heart desease according to claim 1 and 2 is characterized in that: described Fructus Crataegi is a Beishan Mountain Fructus Crataegi.
4. the medicine of treatment ischemic heart desease according to claim 1 and 2 is characterized in that: described Radix Salviae Miltiorrhizae is a wild Radix Salviae Miltiorrhizae.
5. the medicine of treatment ischemic heart desease according to claim 3 is characterized in that: described Radix Salviae Miltiorrhizae is a wild Radix Salviae Miltiorrhizae.
6. the medicine of treatment ischemic heart desease according to claim 1 and 2 is characterized in that: the described Radix Polygoni Multiflori is Yunnan-Guizhou Radix Polygoni Multiflori Preparata.
7. the medicine of treatment ischemic heart desease according to claim 5 is characterized in that: the described Radix Polygoni Multiflori is Yunnan-Guizhou Radix Polygoni Multiflori Preparata.
8. the medicine of treatment ischemic heart desease according to claim 1 and 2 is characterized in that: described Radix Notoginseng is the Yunnan Typhonium flagelliforme (Lodd.) Blume, and the described Radix Paeoniae Alba is a Radix Paeoniae Alba, and described Radix Codonopsis is a wild codonopsis, and the described Rhizoma Atractylodis Macrocephalae is the Zhejiang Rhizoma Atractylodis Macrocephalae.
9. the medicine of treatment ischemic heart desease according to claim 7 is characterized in that: described Radix Notoginseng is the Yunnan Typhonium flagelliforme (Lodd.) Blume, and described Radix Paeoniae Alba is a Radix Paeoniae Alba, and described Radix Codonopsis is a wild codonopsis, and the described Rhizoma Atractylodis Macrocephalae is the Zhejiang Rhizoma Atractylodis Macrocephalae.
10. the preparation method of the medicine of claim 1 or 2 described treatment ischemic heart desease, it is characterized in that: respectively Radix Astragali, Fructus Crataegi, Radix Salviae Miltiorrhizae, the Radix Polygoni Multiflori, Radix Notoginseng, Cortex Cinnamomi, the Radix Paeoniae Alba, Semen Ziziphi Spinosae, Radix Et Rhizoma Nardostachyos, Radix Codonopsis, Bulbus Allii Macrostemonis, trichosanthes fruit, the Rhizoma Atractylodis Macrocephalae of above-mentioned weight portion are put into baking oven, 65~75 ℃ of oven dry, pulverize the back and cross 120 mesh sieves, mixing then, adding weight in the medical material fine powder is the Mel making pellets by mixing medical powder with honey of 1~1.2 times of medical material fine powder gross weight, every ball 9 grams.
CN2008100496707A 2008-04-29 2008-04-29 Medicament for treating ischemic heart disease and preparation method thereof Expired - Fee Related CN101569708B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2008100496707A CN101569708B (en) 2008-04-29 2008-04-29 Medicament for treating ischemic heart disease and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2008100496707A CN101569708B (en) 2008-04-29 2008-04-29 Medicament for treating ischemic heart disease and preparation method thereof

Publications (2)

Publication Number Publication Date
CN101569708A CN101569708A (en) 2009-11-04
CN101569708B true CN101569708B (en) 2011-05-11

Family

ID=41229277

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008100496707A Expired - Fee Related CN101569708B (en) 2008-04-29 2008-04-29 Medicament for treating ischemic heart disease and preparation method thereof

Country Status (1)

Country Link
CN (1) CN101569708B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102058757B (en) * 2010-11-25 2012-07-04 代龙 Traditional Chinese medicinal composition for treating cardiovascular diseases and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1130527A (en) * 1995-08-24 1996-09-11 傅鹤年 Xinshouling capsule for treating heart diseases
CN1891279A (en) * 2005-07-06 2007-01-10 陈克治 Capsule for treating cardio-cerebrovasular disease
CN101057946A (en) * 2007-05-09 2007-10-24 王云花 Traditional Chinese medicine for treating heart disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1130527A (en) * 1995-08-24 1996-09-11 傅鹤年 Xinshouling capsule for treating heart diseases
CN1891279A (en) * 2005-07-06 2007-01-10 陈克治 Capsule for treating cardio-cerebrovasular disease
CN101057946A (en) * 2007-05-09 2007-10-24 王云花 Traditional Chinese medicine for treating heart disease

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
余信之.益气养心汤为主治疗难治性心力衰竭疗效观察.《湖北中医杂志》.2007,第29卷(第10期),25-26. *
曹长恩等.中医药治疗冠心病的研究近况.《中医药信息》.2000,(第6期),13-16. *

Also Published As

Publication number Publication date
CN101569708A (en) 2009-11-04

Similar Documents

Publication Publication Date Title
CN101716242B (en) Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases
CN101199738B (en) Medicament for treating cough and gasp disease
CN101095768B (en) Chinese traditional medicine capsule for treating primary hypertension for persons in middle and old age
CN101837060B (en) Chinese medicine for adjusting hypertension, hyperlipidemia and hyperglycemia
CN104069162B (en) A kind of Chinese medicine for treating urarthritis and various bone joint pains
CN103127366B (en) Chinese materia medica preparation for treating diabetic heart disease
CN101912567B (en) Chinese medicinal prescription for treating chronic myocarditis
CN103301386A (en) Pill for treating qi failing to consolidate semen and preparation method thereof
CN102743455B (en) Chinese patent medicine for treating diabetes mellitus
CN102210839A (en) Traditional Chinese medicine capsule for treating coronary heart disease
CN101284093B (en) Chinese herb medicine for treating coronary heart disease
CN101569708B (en) Medicament for treating ischemic heart disease and preparation method thereof
CN1253196C (en) Medicine for treating colitis
CN101703660B (en) Anti-aging medicament
CN101229360B (en) Anti-AIDS medicine
CN102652822A (en) Traditional Chinese medicine oral liquid used for curing coronary heart disease
CN102935214A (en) Traditional Chinese medicinal composition for treating uremia
CN105770834B (en) A kind of Chinese medicinal pill for treating polymyalgia rheumatica
CN104758888A (en) Traditional Chinese medicine composition for treating diabetes
CN104758889A (en) Traditional Chinese medicine composition for treating diabetes
CN104435900A (en) Medicine for treating rheumatic arthritis and preparation method
CN115300595A (en) Guxindan capsule
CN104042892A (en) Traditional Chinese medicine (TCM) granule for treating postnatal constipation and preparation method thereof
CN101837092B (en) Chinese medicament for curing cardiopathy
CN104042993A (en) Traditional Chinese medicinal ointment for relieving postnatal constipation and preparation method thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20110511

Termination date: 20140429