Summary of the invention
Because acquired immune deficiency syndrome (AIDS) is a kind of acquired immunodeficiency disease (AIDS), its pathogen is HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) (HIV), and this virus enters heavy damage human immune system behind the human body, and the characteristics of variability and latency are arranged.So difficult point of the present invention is exactly at the above-mentioned cause of disease, and according to " invigorating YANG group " medical knowledge of traditional Chinese medical science Zheng Qinan, acquired immune deficiency syndrome (AIDS) is carried out the exploration and the research of pathology and medication, through the traditional Chinese medical science " invigorating YANG group " coordinating YIN and YANG, blood-enriching qi-invigorating, warm muscle is sensible, the medical knowledge of warming YANG virus killing, take to debate the method that disease executing controlled, can reach the effectively preventing effect.
The medicine of preventing and treating acquired immune deficiency syndrome (AIDS) that the object of the present invention is to provide a kind of good effect, has no side effect.
The present invention realizes by following technical proposal: a kind of medicine of preventing and treating acquired immune deficiency syndrome (AIDS) is characterized in that being made up of the raw material of following mass parts:
15~35 parts of Cortex Cinnamomis
10~30 parts of Radix Ginsengs
10~30 parts of the Radixs Astragali
5~15 parts in Bulbus Allii
10~25 parts in Radix Glycyrrhizae
10~30 parts of Rhizoma Zingiberiss
15~35 parts of Radix Angelicae Sinensis.
Cortex Cinnamomi in the described medicament composing prescription has the effect of the wind dispelling that is good for the stomach, energy complement sun, and warming the spleen and stomach, removing accumulated cold, promoting blood circulation, bone and muscle strengthening, the dyspnea with rapid and short breath of suffering from a deficiency of the kidney, conjunctival congestion and swelling pain, deficiency and coldness is vomited and diarrhoea, the diaphoresis expelling pathogenic factors from muscles, it is supporing yang to mend fire.Radix Ginseng is tonifying five ZANG-organs, peace spirit, decide soul, spasmolytic is throbbed with fear, except that pathogen, make eye bright, happily, the good medicine of Fructus Alpiniae Oxyphyllae, to all deficiency syndrome of men and women, heating night sweat, dizziness and headache, regurgitation tell food, cut off from malaria, the sliding chronic dysentery, frequent micturition pouring drop, overstrain internal injury, apoplexy heatstroke, flaccidity syndrome and arthralgia syndrome, haematemesis, hemoptysis, hematochezia, stranguria with blood metrorrhagia of rushing down have obvious curative effects, can strengthen body immunity.The Radix Astragali has that invigorating QI to consolidate the body surface resistance, diuresis toxin expelling, evacuation of pus, expelling pus and promoting granulation, the deficiency of vital energy are weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle are difficultly burst, burst for a long time do not hold back, function that blood deficiency is withered heat.Its sweet in the mouth of Radix Angelicae Sinensis and weighing specially can be enriched blood, again can promoting the circulation of blood, broken stagnant blood, support fresh blood, and invigorating middle warmer has, in the row benefit is arranged, and is the good medicine of QI invigorating spermatogenesis, settling five organs, benefit manner, the strong bodily form.Rhizoma Zingiberis has the power of recuperating depleted YANG, and all deficiency-cold of the stomach, Yuanyang are wild, stagnation of QI, vomiting are had loose bowels between isolated, the cholera distension of obstructed, the meridians obstruction of obstruction and rejection, cold numbness cold dysentery, regurgitation, all poison of ailment said due to cold or exposure, skin, cold extremities faint pulse etc. can both treat.Radix Glycyrrhizae is the medicine with middle QI invigorating, tonify deficiency detoxifcation, can remove pathogenic heat, slow healthy energy, yin nourishing blood, have strengthening the spleen and stomach, solid in void of gas win, association's negative and positive and uncomfortable battalion defends, the effect of fatigue and weakness, shortness of breath and palpitation, irregularly intermittent and regularly intermittent pulse, cough with copious phlegm, extremity contraction urgency, pain, carbuncle sore tumefacting virus, can control the internal injury of straining, deficiency-weakness of spleen-QI, first YANG deficiency, lung qi decline void, bone and muscle strengthening, longue meat.Bulbus Allii is warm in nature, can circulation of qi promoting removing food stagnancy, the parasite killing detoxifcation has the coldness and pain in the epigastrium of controlling, has loose bowels, effects such as swollen ulcer drug, tinea skin ulcer.
Described medicine makes by the method for following prior art: after raw material was cleaned, dried, powder became fine powder, and mix homogeneously is allocated an amount of medical accessory afterwards into and promptly be can be made into pharmaceutically acceptable any dosage forms such as tablet, capsule, pill, electuary.
Described medicine makes by the method for following prior art: raw material is decocted with water for several times, collecting decoction filters, and filtrate is condensed into thick paste, dry, pulverizing are allocated an amount of medical accessory again into and promptly be can be made into pharmaceutically acceptable any dosage forms such as tablet, capsule, pill, electuary.
The present invention has following advantage and effect: adopt such scheme, make the present invention have tonifying five ZANG-organs, peace spirit, the benefit manner, dredge the meridian passage is regulated the blood microcirculation function, warming the spleen and stomach, bone and muscle strengthening, diuresis, toxin expelling, evacuation of pus, enrich blood, promoting the circulation of blood, nourish blood QI invigorating spermatogenesis, tonify deficiency detoxifcation, strengthening the spleen and stomach, bone and muscle strengthening, longue meat, the circulation of qi promoting removing food stagnancy, cough-relieving, effects such as lung moistening, after the patient took medicine, appetite obviously increased, sleep improves, and body function recovers rapidly, can alleviate incident low grade fever's flu, nausea and vomiting, symptoms such as dysentery, make patient's mind clear, thinking is clear, and body skin ulcer stammerer is fast, fidgety alleviating, be emotionally stable, physical ability and complexion can both be effectively restored.
For showing the present invention's curative effect, the present invention is through following clinical experiment, and its result is as follows:
One, physical data
Selection meets patient's 120 examples of country's free AIDS virus resisting treatment medical science inclusion criteria, wherein, male's 80 examples, women's 40 examples, age between year, average 25 years old, is divided into two groups with 120 routine patients at 19-65 at random, both at aspects such as clinical manifestation, sex, ages by statistics credit analyse there was no significant difference (P>0.05).
Two, Therapeutic Method
All patient's antiviral therapy schemes all adopt standard one line scheme, promptly national free acquired immune deficiency syndrome (AIDS) antiviral therapy handbook (D4T+3TC+NVP or EFV), the medicine of the single clothes of matched group 60 examples AIDS virus resisting, test group 60 example clothes medicine provided by the invention, one time 1~3 gram, every day 3 times, total 4 months courses of treatment, and cut out other related drugs at period in a medicine.
Three, observation index
Observation index comprises clinical symptoms, sign and laboratory indexes, understands patient's medicine toxicity situation and assessment curative effect.Monitored body weight, complete blood count, blood glucose, creatinine, ALT etc., and monitored CD4 per February in every month
+Cell number.
Four, curative effect judgment criteria
1, criterion of therapeutical effect
Cure: the symptom complete obiteration, every index is normal, antisecosis;
Produce effects: clinical cardinal symptom obviously alleviates, and the muscle power part is recovered;
Effectively: cardinal symptom alleviates, and muscle power is not recovered;
Invalid: symptom does not alleviate, poor physical capacity.
2, statistical method
Enumeration data adopts X
2The t check is adopted in check, measurement data.
Total effective rate=cure rate+obvious effective rate+effective percentage
Five, result
1, the doing well,improving situation sees Table 1.
2, untoward reaction
Treatment group patient has no adverse reaction.The matched group patient has digestive tract disease, liver toxicity to take place, and also has symptoms such as erythra, peripheral neuritis to take place.
Table 1, doing well,improving situation (80 example)
|
Cure |
Produce effects |
Effectively |
Invalid |
Effective percentage |
50 matched groups 30 are organized in treatment |
15 |
20 5 |
10 10 |
5 15 |
90.00%50% |
Treatment group curative effect obviously is better than matched group ((p>0.01))
Six, discuss:
The present invention has tonifying five ZANG-organs, peace spirit, benefit manner, dredge the meridian passage is regulated the blood microcirculation function, warming the spleen and stomach, bone and muscle strengthening, diuresis, toxin expelling, evacuation of pus are enriched blood, promoting the circulation of blood, are nourished blood, the QI invigorating spermatogenesis, tonify deficiency detoxifcation, strengthening the spleen and stomach, bone and muscle strengthening, longue meat, circulation of qi promoting removing food stagnancy, effects such as cough-relieving, lung moistening, to human body have detoxifcation, the circulation of qi promoting of enriching blood, strengthening the spleen and stomach, promoting blood circulation, benefit consider, and strengthens important function such as body immunity, premunition.After the patient took, appetite obviously increased, and sleep improves, body function recovers rapidly, can alleviate symptoms such as incident low grade fever's flu, nausea and vomiting, dysentery, make patient's mind clear, thinking is clear, body skin ulcer stammerer is fast, fidgety alleviating is emotionally stable, and physical ability and complexion can both be effectively restored, to compare prevention effect obvious with similar medicine, and toxic and side effects is little.
The specific embodiment
Below in conjunction with embodiment the present invention is described further.
Embodiment 1
Get material by following prescription:
30 kilograms of 15 kilograms of Radix Ginsengs of Cortex Cinnamomi
15 kilograms in 10 kilograms of Bulbus Alliis of the Radix Astragali
30 kilograms of 10 kilograms of Rhizoma Zingiberiss of Radix Glycyrrhizae
15 kilograms of Radix Angelicae Sinensis
Method through following prior art: raw material is decocted with water 3 times, and collecting decoction filters, and filtrate is condensed into thick paste, and an amount of medical accessory is allocated in dry, pulverizing again into, makes tablet with the processing method of prior art.
Embodiment 2
Get material by following prescription:
10 kilograms of 35 kilograms of Radix Ginsengs of Cortex Cinnamomi
5 kilograms in 30 kilograms of Bulbus Alliis of the Radix Astragali
10 kilograms of 25 kilograms of Rhizoma Zingiberiss of Radix Glycyrrhizae
35 kilograms of Radix Angelicae Sinensis
Method through following prior art: raw material is decocted with water 2 times, and collecting decoction filters, and filtrate is condensed into thick paste, and an amount of medical accessory is allocated in dry, pulverizing again into, makes pill with the processing method of prior art.
Embodiment 3
Get material by following prescription:
20 kilograms of 25 kilograms of Radix Ginsengs of Cortex Cinnamomi
10 kilograms in 20 kilograms of Bulbus Alliis of the Radix Astragali
20 kilograms of 15 kilograms of Rhizoma Zingiberiss of Radix Glycyrrhizae
25 kilograms of Radix Angelicae Sinensis
Method through following prior art: raw material is decocted with water for several times, and collecting decoction filters, filtrate is condensed into thick paste, an amount of medical accessory is allocated in dry, pulverizing again into, makes the pharmaceutically acceptable dosage form of pill or electuary or other with the processing method of prior art.
Embodiment 4
Get material by following prescription:
10 kilograms of 15 kilograms of Radix Ginsengs of Cortex Cinnamomi
5 kilograms in 10 kilograms of Bulbus Alliis of the Radix Astragali
10 kilograms of 10 kilograms of Rhizoma Zingiberiss of Radix Glycyrrhizae
15 kilograms of Radix Angelicae Sinensis
Pass through the method for following prior art: after raw material was cleaned, dried, powder became fine powder, and mix homogeneously is allocated an amount of medical accessory afterwards into, and makes capsule with the processing method of prior art.
Embodiment 5
Get material by following prescription:
30 kilograms of 35 kilograms of Radix Ginsengs of Cortex Cinnamomi
15 kilograms in 30 kilograms of Bulbus Alliis of the Radix Astragali
30 kilograms of 25 kilograms of Rhizoma Zingiberiss of Radix Glycyrrhizae
35 kilograms of Radix Angelicae Sinensis
Pass through the method for following prior art: after raw material was cleaned, dried, powder became fine powder, and mix homogeneously is allocated an amount of medical accessory afterwards into, and makes electuary with the processing method of prior art.